ATE485034T1 - Beschichteter nikotinhaltiger kaugummi, seine herstellung und verwendung - Google Patents

Beschichteter nikotinhaltiger kaugummi, seine herstellung und verwendung

Info

Publication number
ATE485034T1
ATE485034T1 AT02744014T AT02744014T ATE485034T1 AT E485034 T1 ATE485034 T1 AT E485034T1 AT 02744014 T AT02744014 T AT 02744014T AT 02744014 T AT02744014 T AT 02744014T AT E485034 T1 ATE485034 T1 AT E485034T1
Authority
AT
Austria
Prior art keywords
production
chewing gum
nicotine chewing
coated nicotine
coated
Prior art date
Application number
AT02744014T
Other languages
English (en)
Inventor
Katarina Lindell
Nils-Olof Lindberg
Roland Olsson
Original Assignee
Mcneil Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mcneil Ab filed Critical Mcneil Ab
Application granted granted Critical
Publication of ATE485034T1 publication Critical patent/ATE485034T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00Chewing gum
    • A23G4/06Chewing gum characterised by the composition containing organic or inorganic compounds
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23BPRESERVING, e.g. BY CANNING, MEAT, FISH, EGGS, FRUIT, VEGETABLES, EDIBLE SEEDS; CHEMICAL RIPENING OF FRUIT OR VEGETABLES; THE PRESERVED, RIPENED, OR CANNED PRODUCTS
    • A23B4/00General methods for preserving meat, sausages, fish or fish products
    • A23B4/10Coating with a protective layer; Compositions or apparatus therefor
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00Chewing gum
    • A23G4/02Apparatus specially adapted for manufacture or treatment of chewing gum
    • A23G4/04Apparatus specially adapted for manufacture or treatment of chewing gum for moulding or shaping
    • A23G4/043Apparatus specially adapted for manufacture or treatment of chewing gum for moulding or shaping for composite chewing gum
    • A23G4/046Apparatus specially adapted for manufacture or treatment of chewing gum for moulding or shaping for composite chewing gum with a centre made of chewing gum
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00Chewing gum
    • A23G4/06Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/12Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G4/126Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing vitamins, antibiotics
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00Chewing gum
    • A23G4/18Chewing gum characterised by shape, structure or physical form, e.g. aerated products
    • A23G4/20Composite products, e.g. centre-filled, multi-layer, laminated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058Chewing gums
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34Tobacco-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT02744014T 2001-06-20 2002-06-14 Beschichteter nikotinhaltiger kaugummi, seine herstellung und verwendung ATE485034T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0102197A SE0102197D0 (sv) 2001-06-20 2001-06-20 New product and use and manufacture thereof
PCT/SE2002/001158 WO2002102357A1 (en) 2001-06-20 2002-06-14 A coated nicotine-containing chewing gum, manufacture and use thereof

Publications (1)

Publication Number Publication Date
ATE485034T1 true ATE485034T1 (de) 2010-11-15

Family

ID=20284551

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02744014T ATE485034T1 (de) 2001-06-20 2002-06-14 Beschichteter nikotinhaltiger kaugummi, seine herstellung und verwendung

Country Status (19)

Country Link
US (2) US20040194793A1 (de)
EP (1) EP1404306B1 (de)
JP (2) JP4571402B2 (de)
AR (1) AR034527A1 (de)
AT (1) ATE485034T1 (de)
AU (1) AU2002345454B2 (de)
BR (1) BR0210342A (de)
CA (1) CA2449298C (de)
CZ (1) CZ20033458A3 (de)
DE (1) DE60238054D1 (de)
DK (1) DK1404306T3 (de)
ES (1) ES2352681T3 (de)
IL (2) IL159425A0 (de)
MX (1) MXPA03011557A (de)
NZ (1) NZ529780A (de)
RU (1) RU2291688C2 (de)
SE (1) SE0102197D0 (de)
WO (1) WO2002102357A1 (de)
ZA (1) ZA200309204B (de)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1578422E (pt) 2002-12-20 2007-06-14 Niconovum Ab Material particulado contendo nicotina fisicamente e quimicamente estável
SE0302947D0 (sv) 2003-01-24 2003-11-07 Magle Ab A composition material for transmucosal delivery
EP1617823B1 (de) * 2003-01-24 2019-01-09 Nicachet AB Beutel mit nikotinhaltiger zusammensetzung zur transmukosalen abgabe
ATE369750T1 (de) * 2003-02-04 2007-09-15 Gumlink As Gepresste kaugummitablette
EP1449525A1 (de) * 2003-02-20 2004-08-25 Cross Chem Llc Kaugummi in der Form von Mehrschichttabletten
US8529875B2 (en) 2004-06-29 2013-09-10 Fertin Pharma A/S Tobacco alkaloid releasing chewing gum
BRPI0513465B1 (pt) * 2004-08-11 2015-08-11 Intercontinental Great Brands Llc Composições orais, artigo comestível, composições para balas e goma de mascar, métodos para preparação do referido artigo e para fornercer sensação às áreas receptoras orais
US7780981B2 (en) 2004-09-13 2010-08-24 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
CN101039587B (zh) 2004-10-08 2012-07-18 古木林科有限公司 糖果产品
US8524196B2 (en) 2004-11-30 2013-09-03 Fertin Pharma A/S Method of providing fast relief to a user of a nicotine chewing gum
US8323683B2 (en) 2005-05-18 2012-12-04 Mcneil-Ppc, Inc. Flavoring of drug-containing chewing gums
US8709502B2 (en) * 2005-09-23 2014-04-29 Chanel Parfums Beaute Extract of Vanilla planifolia
US8024911B2 (en) 2006-02-16 2011-09-27 Mcneil Ab Method for blister packing
EP1998754A2 (de) * 2006-03-16 2008-12-10 NicoNovum AB Stabile lutschtabletten-zusammensetzungen mit schneller nikotinfreisetzung
EP1998748B1 (de) 2006-03-16 2015-01-14 NicoNovum AB Verbesserte schnupftabakzusammensetzung
US20070269386A1 (en) 2006-05-16 2007-11-22 Per Steen New product and use and manufacture thereof
US20070269492A1 (en) * 2006-05-16 2007-11-22 Per Steen New product and use and manufacture thereof
US8642016B2 (en) * 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
AU2012241150B2 (en) * 2006-07-21 2015-04-16 Jsrnti, Llc Medicinal delivery system and related methods
US20100209359A1 (en) * 2007-02-26 2010-08-19 Revolymer Limited Medicated chewing gum
CA2682323A1 (en) * 2007-04-02 2008-10-09 Parkinson's Institute Methods and compositions for reduction of side effects of therapeutic treatments
US20080286340A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered nicotine containing products
US20080286341A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered coated nicotine containing products
JP2010538669A (ja) * 2007-09-18 2010-12-16 ニコノヴァム エービー ニコチンの迅速な放出をもたらす、マルチトールを含有する安定なチューイングガム組成物
JP2009102287A (ja) * 2007-10-19 2009-05-14 Seiji Sakao 禁煙用の辛い唐辛子
WO2009080022A1 (en) * 2007-12-20 2009-07-02 Fertin Pharma A/S Compressed chewing gum tablet
DK2229156T3 (en) 2007-12-20 2017-02-06 Fertin Pharma As CHEW GUM TABLE AND PROCEDURE FOR DOSING PHARMACEUTICAL ACTIVE INGREDIENTS IN SUCH CHEW GUM TABLE
DK2229157T3 (en) 2007-12-20 2016-12-05 Fertin Pharma As Compressed chewing gum tablet
CL2009001025A1 (es) 2008-05-01 2010-09-24 Smithkline Beecham Corp Composicion de pastilla para chupar que comprende: a) un granulo patron con al menos: un agente tampon alcalino, un modificador de la disolucion y una carga, b) un principio activo de nicotina definido extragranular y al menos un agente tampon alcalino; procedimiento de preparacion; util para eliminar o reducir el uso de tabaco.
AR071850A1 (es) 2008-05-21 2010-07-21 Novartis Ag Gomas de mascar en forma de tableta
DK2282645T3 (en) 2008-05-26 2015-07-13 Fertin Pharma As Flavor impregnation of a chewing gum
US9700525B2 (en) 2008-08-20 2017-07-11 Board Of Supervisors Of Louisiana State University And Agricultural & Mechanical College Continuous local slow-release of therapeutics for head and neck problems and upper aerodigestive disorders
CA2736531C (en) * 2008-09-17 2016-10-25 Niconovum Ab Process for preparing snuff composition
JP2012505878A (ja) * 2008-10-14 2012-03-08 マクニール アーベー 複数部分口内剤形及びその使用
US8506936B2 (en) 2008-11-25 2013-08-13 Watson Laboratories, Inc. Stabilized nicotine chewing gum
US9307787B2 (en) * 2008-12-19 2016-04-12 U.S. Smokeless Tobacco Company Llc Tobacco granules and method of producing tobacco granules
WO2010069311A1 (en) 2008-12-19 2010-06-24 Fertin Pharma A/S Multi-part kit
EP2233134A1 (de) * 2009-03-27 2010-09-29 McNeil AB Mehrteilige intraorale Darreichungsform mit organoleptischen Eigenschaften
EP2442668B1 (de) 2009-06-19 2016-08-10 Fertin Pharma A/S Gepufferte gummibasis für hohe ph-freisetzung
RU2417095C1 (ru) * 2010-02-12 2011-04-27 Александр Ицхокович Кашлинский Средство "куримало" ("км"), снижающее тягу к курению
US20110268809A1 (en) 2010-04-28 2011-11-03 Paul Andrew Brinkley Nicotine-Containing Pharmaceutical Compositions
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
US8529914B2 (en) * 2010-06-28 2013-09-10 Richard C. Fuisz Bioactive dose having containing a material for modulating pH of a bodily fluid to help or hinder absorption of a bioactive
CA2841785A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
EP2768477A1 (de) * 2011-10-19 2014-08-27 Fertin Pharma A/S Nikotinkaugummi mit verbesserter nikotinnutzung
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
US20130177646A1 (en) * 2012-01-05 2013-07-11 Mcneil Ab Solid Nicotine-Comprising Dosage Form with Reduced Organoleptic Disturbance
US10130120B2 (en) 2013-03-15 2018-11-20 Altria Client Services Llc Use of pectin or other anionic polymers in the stabilization and controlled release of nicotine in oral sensorial tobacco products or nicotine containing non-tobacco oral sensorial products
EP3021699B1 (de) * 2013-07-19 2023-09-13 Altria Client Services LLC Flüssigaerosolformulierung eines elektronischen rauchartikels
CN103478893B (zh) * 2013-09-09 2016-02-10 湖南中烟工业有限责任公司 茶氨酸在胶基咀嚼型无烟气烟草制品中的应用
CN106456560B (zh) 2014-04-08 2021-04-06 费尔廷制药公司 医用口香糖
US9744128B2 (en) * 2014-06-05 2017-08-29 Mastix LLC Method for manufacturing medicated chewing gum without cooling
JP2018511355A (ja) 2015-01-28 2018-04-26 クロノ セラピューティクス インコーポレイテッドChrono Therapeutics Inc. 薬剤送達方法及びシステム
WO2016145373A1 (en) 2015-03-12 2016-09-15 Chrono Therapeutics Inc. Craving input and support system
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
US11311623B2 (en) 2016-04-21 2022-04-26 Fertin Pharma A/S Nicotine delivery product, related uses and oral dosage forms, and methods of production
US10765658B2 (en) 2016-06-22 2020-09-08 Mastix LLC Oral compositions delivering therapeutically effective amounts of cannabinoids
US10632076B2 (en) 2016-11-18 2020-04-28 Fertin Pharma A/S Tablet comprising separate binder and erythritol
US10543205B2 (en) 2016-11-18 2020-01-28 Fertin Pharma A/S Oral delivery vehicle containing nicotine
CA3049529A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
SE541358C2 (en) 2017-05-30 2019-08-13 Enorama Pharma Ab Nicotine-containing chewing gum compositions
RU2770035C1 (ru) * 2018-05-17 2022-04-14 Фертин Фарма А/С Таблетированная жевательная резинка, подходящая для активных фармацевтических ингредиентов
US20190350858A1 (en) 2018-05-17 2019-11-21 Fertin Pharma A/S Oral tablet for delivery of active ingredients to the gastrointestinal tract
US11058641B2 (en) 2018-05-17 2021-07-13 Fertin Pharma A/S Oral tablet for taste masking of active ingredients
US11052047B2 (en) 2018-05-17 2021-07-06 Fertin Pharma A/S Oral tablet suitable for fast release of active pharmaceutical ingredients
US11096894B2 (en) 2018-05-17 2021-08-24 Fertin Pharma A/S Oral tablet for induced saliva generation
US11135157B2 (en) 2018-05-17 2021-10-05 Fertin Pharma A/S Oral tablet for delivery of active ingredients to the throat
US11090263B2 (en) 2018-05-22 2021-08-17 Fertin Pharma A/S Tableted chewing gum suitable for active pharmaceutical ingredients
US11058633B2 (en) 2018-05-17 2021-07-13 Fertin Pharma A/S Disintegrating oral tablet suitable for active pharmaceutical ingredients
US11096895B2 (en) * 2018-05-17 2021-08-24 Fertin Pharma A/S Oral tablet suitable for active pharmaceutical ingredients
US11096896B2 (en) 2018-05-17 2021-08-24 Fertin Pharma A/S Tablet dosage form for buccal absorption of active ingredients
JP7420797B2 (ja) 2018-05-29 2024-01-23 モーニングサイド ベンチャー インベストメンツ リミテッド 薬剤送達の方法及びシステム
EP3807260A1 (de) 2018-06-15 2021-04-21 R. J. Reynolds Tobacco Company Reinigung von nikotin
MX2021000466A (es) 2018-07-13 2021-03-25 Mcneil Ab Goma de mascar que comprende nicotina.
CN108991596B (zh) * 2018-10-11 2020-07-28 玉溪开元金蓝生物科技有限责任公司 复方滇橄榄添加料、制备方法及其在香烟滤嘴棒上的应用
WO2021144365A1 (en) * 2020-01-15 2021-07-22 Mcneil Ab Product and manufacturing process for a gum
WO2022224200A1 (en) * 2021-04-22 2022-10-27 Nicoventures Trading Limited Oral compositions and methods of manufacture

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3877468A (en) * 1970-07-22 1975-04-15 Leo Ab Chewable tobacco substitute composition
US3901248A (en) * 1970-07-22 1975-08-26 Leo Ab Chewable smoking substitute composition
US3845217A (en) * 1972-11-16 1974-10-29 Helsingborg L Ab Buffered smoking substitute compositions
US4366211A (en) 1981-09-21 1982-12-28 Westinghouse Electric Corp. Control of electrolyte fill to fuel cell stack
GB8301659D0 (en) * 1983-01-21 1983-02-23 Leo Ab Smoking substitutes
US4920989A (en) * 1985-04-25 1990-05-01 Regents Of The University Of California Method and apparatus for aiding in the reduction of incidence of tobacco smoking
GB8615676D0 (en) * 1986-06-26 1986-07-30 Stoppers Co Ltd Nicotine containing lozenge
US5057328A (en) * 1988-11-14 1991-10-15 Warner-Lambert Company Food acid delivery systems containing polyvinyl acetate
US5154939A (en) * 1989-04-19 1992-10-13 Wm. Wrigley Jr. Company Use of salt to improve extrusion encapsulation of chewing gum ingredients
US5167242A (en) * 1990-06-08 1992-12-01 Kabi Pharmacia Aktiebolaq Nicotine-impermeable container and method of fabricating the same
GB9200047D0 (en) * 1992-01-03 1992-02-26 Univ Alberta Nicotine-containing nasal spray
US6024097A (en) * 1992-02-20 2000-02-15 J Mom Trust Product for assisting a smoker in giving up the habit
US5869505A (en) * 1993-02-02 1999-02-09 Keenan; Robert M. Nicotine metabolites and nicotine dependence
US5549906A (en) * 1993-07-26 1996-08-27 Pharmacia Ab Nicotine lozenge and therapeutic method for smoking cessation
US5362496A (en) * 1993-08-04 1994-11-08 Pharmetrix Corporation Method and therapeutic system for smoking cessation
SE9303574D0 (sv) * 1993-11-01 1993-11-01 Kabi Pharmacia Ab Composition for drug delivery and method the manufacturing thereof
GB2289204B (en) 1994-04-21 1998-01-14 Williamson Research Limited A chewing gum for use as a nicotine substitute and slimming aid
US5810018A (en) * 1994-12-29 1998-09-22 Monte; Woodrow C. Method, composition and apparatus for reducing the incidence of cigarette smoking
ATE300937T1 (de) * 1995-05-11 2005-08-15 Univ Utah Res Found Tabakersatz
US5955098A (en) * 1996-04-12 1999-09-21 Flemington Pharmaceutical Corp. Buccal non polar spray or capsule
HU224035B1 (hu) * 1996-05-13 2005-05-30 Novartis Consumer Health S.A. Bukkális adagolórendszer
WO2000035298A1 (en) * 1996-11-27 2000-06-22 Wm. Wrigley Jr. Company Chewing gum containing medicament active agents
WO1998023165A1 (en) 1996-11-27 1998-06-04 Wm. Wrigley Jr. Company Method of controlling release of caffeine in chewing gum and gum produced thereby
US6413496B1 (en) * 1996-12-04 2002-07-02 Biogland Ireland (R&D) Limited Pharmaceutical compositions and devices for their administration
ATE388687T1 (de) * 1998-09-03 2008-03-15 Jsr Nti Llc Medikamentöse verabreichung von nikotin in form von kaugummi
AU6412299A (en) 1998-10-08 2000-04-26 Biovail Technologies Limited Composition and method for medicated chewing gum delivery system
US6586023B1 (en) * 1998-12-15 2003-07-01 Wm. Wrigley Jr. Company Process for controlling release of active agents from a chewing gum coating and product thereof
BR9917220A (pt) * 1999-03-22 2001-12-26 Atp Avant Garde Technologies & Composição para gomas de mascarmedicamentosas, processo para produção damesma, e tabletes assim obtidos

Also Published As

Publication number Publication date
WO2002102357A1 (en) 2002-12-27
RU2003137595A (ru) 2005-02-10
DE60238054D1 (de) 2010-12-02
CA2449298C (en) 2011-08-02
AR034527A1 (es) 2004-02-25
JP4571402B2 (ja) 2010-10-27
AU2002345454B2 (en) 2006-07-20
US20040194793A1 (en) 2004-10-07
CA2449298A1 (en) 2002-12-27
IL159425A0 (en) 2004-06-01
ZA200309204B (en) 2005-02-23
MXPA03011557A (es) 2004-03-18
US20120017924A1 (en) 2012-01-26
SE0102197D0 (sv) 2001-06-20
ES2352681T3 (es) 2011-02-22
NZ529780A (en) 2006-04-28
EP1404306A1 (de) 2004-04-07
IL159425A (en) 2006-12-10
BR0210342A (pt) 2004-07-13
EP1404306B1 (de) 2010-10-20
JP2010070564A (ja) 2010-04-02
RU2291688C2 (ru) 2007-01-20
CZ20033458A3 (en) 2004-05-12
JP2005500296A (ja) 2005-01-06
DK1404306T3 (da) 2011-01-24

Similar Documents

Publication Publication Date Title
ATE485034T1 (de) Beschichteter nikotinhaltiger kaugummi, seine herstellung und verwendung
DE60044790D1 (de) Aerogelsubstrat und seine Herstellung
DE60038200D1 (de) ren Herstellung und Verwendung
ATE286021T1 (de) Substituierte phenylderivate, ihre herstellung und verwendung
ATE294171T1 (de) Phenylsulfonyl-1,3-dihydro-2h-indol-2-on derivate,deren herstellung und deren therapeutische verwendung
NO20024293L (no) Flekkfjernende tyggegummi og konfektblandinger, og fremgangsmÕter for fremstilling av samme
ATE441635T1 (de) 4-cyanopyrazol-3-carbonsäureamidderivate, herstellung und therapeutische anwendung davon
AU2003241185A1 (en) Antibacterial flavor and fragrance composition and halitosis-inhibition flavor and fragrance composition and oral care composition containing the same
DE60239896D1 (de) Velourskunstleder und seine herstellung
DE60041916D1 (de) Elektonikbauteil-träger und seine herstellung
ATE372998T1 (de) 1-aminophthalazinderivate, deren herstellung und deren therapeutische verwendung
DE59901613D1 (de) Beta-1,3-Glucan aus Euglena enthaltendes gefriergetrocknetes Erzeugnis, seine Herstellung und Verwendung
EP1654114A4 (de) Silberhaltige wundpflegevorrichtung, zusammensetzung dafür und herstellungsverfahren
ITTO20000394A0 (it) Gomma da masticare.
DE69901177T2 (de) Platinkomplex, dessen herstellung und dessen therapeutische verwendung
ATE409184T1 (de) Dioxan-2-alkylkarbamaten derivaten, deren herstellung und deren therapeutischen verwendung
AU2003298583A8 (en) Chewing gum formulation and method of making the same
ATE336491T1 (de) Piperazinylacylpiperidinderivate, deren herstellung und deren therapeutische anwendung
DE60015004D1 (de) Russ, seine Herstellung und Verwendungen
ATE380568T1 (de) Kaugummi und konfekt zur mundpflege
DE60208044D1 (de) Acylaminothiazolderivate, deren herstellung und deren therapeutische verwendung
ZA200309825B (en) Chewing gum to control malodorous breath
ATE251170T1 (de) Titanverbindungen, deren herstellung und verwendung
DE69810521D1 (de) Abbeizzusammensetzungen, ihre Herstellung und Verwendung
DE60228468D1 (de) Kunstzähne und ihre herstellung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties