SE9303574D0 - Composition for drug delivery and method the manufacturing thereof - Google Patents

Composition for drug delivery and method the manufacturing thereof

Info

Publication number
SE9303574D0
SE9303574D0 SE9303574A SE9303574A SE9303574D0 SE 9303574 D0 SE9303574 D0 SE 9303574D0 SE 9303574 A SE9303574 A SE 9303574A SE 9303574 A SE9303574 A SE 9303574A SE 9303574 D0 SE9303574 D0 SE 9303574D0
Authority
SE
Sweden
Prior art keywords
pct
manufacturing
pharmaceutical composition
around
starch microspheres
Prior art date
Application number
SE9303574A
Other languages
English (en)
Inventor
Sten Albrechtsen
Lene Orup-Jacobsen
Jens Hansen
Birgitte Moellgaard
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Priority to SE9303574A priority Critical patent/SE9303574D0/sv
Publication of SE9303574D0 publication Critical patent/SE9303574D0/sv
Priority to ES95900330T priority patent/ES2160689T3/es
Priority to PCT/SE1994/000917 priority patent/WO1995012399A1/en
Priority to AT95900330T priority patent/ATE203407T1/de
Priority to NZ275903A priority patent/NZ275903A/en
Priority to US08/640,873 priority patent/US5939100A/en
Priority to DK95900330T priority patent/DK0739206T3/da
Priority to CA002173504A priority patent/CA2173504C/en
Priority to AU81184/94A priority patent/AU682228B2/en
Priority to EP95900330A priority patent/EP0739206B1/en
Priority to PT95900330T priority patent/PT739206E/pt
Priority to DE69427832T priority patent/DE69427832T2/de
Priority to JP7513154A priority patent/JPH09504305A/ja
Priority to GR20010401834T priority patent/GR3036964T3/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
SE9303574A 1993-11-01 1993-11-01 Composition for drug delivery and method the manufacturing thereof SE9303574D0 (sv)

Priority Applications (14)

Application Number Priority Date Filing Date Title
SE9303574A SE9303574D0 (sv) 1993-11-01 1993-11-01 Composition for drug delivery and method the manufacturing thereof
JP7513154A JPH09504305A (ja) 1993-11-01 1994-10-03 ニコチンまたはその誘導体およびデンプン微小球からなるドラッグデリバリー用組成物およびその製法
DK95900330T DK0739206T3 (da) 1993-11-01 1994-10-03 Præparat til afgivelse af lægemiddel indeholdende nikotin eller et derivat deraf og stivelsesmikrokugler, samt fremgangsmåde til fremstilling heraf
PCT/SE1994/000917 WO1995012399A1 (en) 1993-11-01 1994-10-03 Composition for drug delivery comprising nicotine or a derivative thereof and starch microspheres and method for the manufacturing thereof
AT95900330T ATE203407T1 (de) 1993-11-01 1994-10-03 Arzneistoffabgabepräparat, das nikotin oder ein derivat davon und stärkemikrokügelchen enthält, und verfahren für seine herstellung
NZ275903A NZ275903A (en) 1993-11-01 1994-10-03 Nicotine bound to starch microspheres in a composition that is suitable for oral or nasal administration by smokers
US08/640,873 US5939100A (en) 1993-11-01 1994-10-03 Composition for drug delivery comprising nicotine or a derivative thereof and starch microspheres and method for the manufacturing thereof
ES95900330T ES2160689T3 (es) 1993-11-01 1994-10-03 Composicion para aporte de farmacos que comprende nicotina o un derivado de la misma y microesferas de almidon y metodo para la fabricacion de la misma.
CA002173504A CA2173504C (en) 1993-11-01 1994-10-03 Composition for drug delivery comprising nicotine or a derivative thereof and starch microspheres and method for the manufacturing thereof
AU81184/94A AU682228B2 (en) 1993-11-01 1994-10-03 Composition for drug delivery comprising nicotine or a derivative thereof and starch microspheres and method for the manufacturing thereof
EP95900330A EP0739206B1 (en) 1993-11-01 1994-10-03 Composition for drug delivery comprising nicotine or a derivative thereof and starch microspheres and method for the manufacturing thereof
PT95900330T PT739206E (pt) 1993-11-01 1994-10-03 Composicoes para a entrega de medicamentos que compreende nicotina ou um seu derivado e microsferas de amido e um metodo de procedimento
DE69427832T DE69427832T2 (de) 1993-11-01 1994-10-03 Arzneistoffabgabepräparat, das nikotin oder ein derivat davon und stärkemikrokügelchen enthält, und verfahren für seine herstellung
GR20010401834T GR3036964T3 (en) 1993-11-01 2001-10-22 Composition for drug delivery comprising nicotine or a derivative thereof and starch microspheres and method for the manufacturing thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9303574A SE9303574D0 (sv) 1993-11-01 1993-11-01 Composition for drug delivery and method the manufacturing thereof

Publications (1)

Publication Number Publication Date
SE9303574D0 true SE9303574D0 (sv) 1993-11-01

Family

ID=20391581

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9303574A SE9303574D0 (sv) 1993-11-01 1993-11-01 Composition for drug delivery and method the manufacturing thereof

Country Status (13)

Country Link
US (1) US5939100A (sv)
EP (1) EP0739206B1 (sv)
JP (1) JPH09504305A (sv)
AT (1) ATE203407T1 (sv)
AU (1) AU682228B2 (sv)
DE (1) DE69427832T2 (sv)
DK (1) DK0739206T3 (sv)
ES (1) ES2160689T3 (sv)
GR (1) GR3036964T3 (sv)
NZ (1) NZ275903A (sv)
PT (1) PT739206E (sv)
SE (1) SE9303574D0 (sv)
WO (1) WO1995012399A1 (sv)

Families Citing this family (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2231968A1 (en) * 1998-03-11 1999-09-11 Smoke-Stop, A Partnership Consisting Of Art Slutsky Method of producing a nicotine medicament
US6344222B1 (en) 1998-09-03 2002-02-05 Jsr Llc Medicated chewing gum delivery system for nicotine
US6358060B2 (en) 1998-09-03 2002-03-19 Jsr Llc Two-stage transmucosal medicine delivery system for symptom relief
US20080138399A1 (en) * 1999-07-16 2008-06-12 Aradigm Corporation Dual release nicotine formulations, and systems and methods for their use
US8256433B2 (en) * 1999-07-16 2012-09-04 Aradigm Corporation Systems and methods for effecting cessation of tobacco use
US6799576B2 (en) * 1999-07-16 2004-10-05 Aradigm Corporation System for effecting smoking cessation
US20080138398A1 (en) * 1999-07-16 2008-06-12 Aradigm Corporation Dual release nicotine formulations, and systems and methods for their use
US20080138294A1 (en) * 1999-07-16 2008-06-12 Igor Gonda Systems and methods for effecting cessation of tobacco use
AU777326B2 (en) * 1999-07-16 2004-10-14 Aradigm Corporation System for effecting smoke cessation
WO2001089476A1 (en) * 2000-05-19 2001-11-29 Npd Llc Chewing gums, lozenges, candies, tablets, liquids, and sprays for efficient delivery of medications and dietary supplements
US8067032B2 (en) 2000-12-22 2011-11-29 Baxter International Inc. Method for preparing submicron particles of antineoplastic agents
US6951656B2 (en) * 2000-12-22 2005-10-04 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US9700866B2 (en) 2000-12-22 2017-07-11 Baxter International Inc. Surfactant systems for delivery of organic compounds
US6884436B2 (en) * 2000-12-22 2005-04-26 Baxter International Inc. Method for preparing submicron particle suspensions
US6607784B2 (en) * 2000-12-22 2003-08-19 Baxter International Inc. Microprecipitation method for preparing submicron suspensions
US20040256749A1 (en) * 2000-12-22 2004-12-23 Mahesh Chaubal Process for production of essentially solvent-free small particles
US20050048126A1 (en) 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
US6977085B2 (en) * 2000-12-22 2005-12-20 Baxter International Inc. Method for preparing submicron suspensions with polymorph control
US7193084B2 (en) 2000-12-22 2007-03-20 Baxter International Inc. Polymorphic form of itraconazole
US20030051728A1 (en) 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
US7458374B2 (en) 2002-05-13 2008-12-02 Alexza Pharmaceuticals, Inc. Method and apparatus for vaporizing a compound
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US7645442B2 (en) 2001-05-24 2010-01-12 Alexza Pharmaceuticals, Inc. Rapid-heating drug delivery article and method of use
SE0102197D0 (sv) * 2001-06-20 2001-06-20 Pharmacia Ab New product and use and manufacture thereof
SE521512C2 (sv) * 2001-06-25 2003-11-11 Niconovum Ab Anordning för administrering av en substans till främre delen av en individs munhåla
US20060003012A9 (en) * 2001-09-26 2006-01-05 Sean Brynjelsen Preparation of submicron solid particle suspensions by sonication of multiphase systems
AU2002337692B2 (en) 2001-09-26 2007-09-13 Baxter International Inc. Preparation of submicron sized nanoparticles via dispersion and solvent or liquid phase removal
US7112340B2 (en) 2001-10-19 2006-09-26 Baxter International Inc. Compositions of and method for preparing stable particles in a frozen aqueous matrix
US20030111088A1 (en) * 2001-10-29 2003-06-19 Addiction Therapies, Inc. Device and method for treating combination dependencies
US20030159702A1 (en) * 2002-01-21 2003-08-28 Lindell Katarina E.A. Formulation and use manufacture thereof
US7767698B2 (en) * 2002-06-03 2010-08-03 Mcneil Ab Formulation and use thereof
US20040091581A1 (en) * 2002-11-08 2004-05-13 Ghislaine Joly Starch/collagen casings for co-extruded food products
US20040105818A1 (en) 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7913688B2 (en) 2002-11-27 2011-03-29 Alexza Pharmaceuticals, Inc. Inhalation device for producing a drug aerosol
BR0317392A (pt) * 2002-12-19 2005-12-20 Pharmacia Corp Formulação não-higroscópica incluindo uma droga higroscópica
PT1578422E (pt) 2002-12-20 2007-06-14 Niconovum Ab Material particulado contendo nicotina fisicamente e quimicamente estável
SE0302947D0 (sv) * 2003-01-24 2003-11-07 Magle Ab A composition material for transmucosal delivery
WO2004073729A1 (ja) 2003-02-21 2004-09-02 Translational Research Ltd. 薬物の経鼻投与用組成物
MXPA05010379A (es) 2003-03-27 2006-05-31 Bioactis Ltd Aparato para administrar una medicina en polvo en la cavidad intranasal.
JP2007516404A (ja) 2003-05-21 2007-06-21 アレックザ ファーマシューティカルズ， インコーポレイテッド 光学点火されたかまたは電気点火された内蔵式加熱ユニットおよびそれを使用する薬剤供給ユニット
CA2537488A1 (en) * 2003-09-08 2005-03-17 Pfizer Health Ab Nicotine formulations and use thereof
US8627828B2 (en) 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
AU2004289248B2 (en) 2003-11-07 2012-05-03 U.S. Smokeless Tobacco Company Llc Tobacco compositions
ES2334681T3 (es) * 2004-03-19 2010-03-15 Mcneil Ab Medios para la administracion transdermica de nicotina.
US7540286B2 (en) 2004-06-03 2009-06-02 Alexza Pharmaceuticals, Inc. Multiple dose condensation aerosol devices and methods of forming condensation aerosols
EP1785145A4 (en) * 2004-08-10 2008-08-13 Translational Res Ltd TRANSNASAL COMPOSITION WITH IMMEDIATE EFFECT AND HIGH RESORBIBILITY
US8322350B2 (en) 2004-12-30 2012-12-04 Philip Morris Usa Inc. Aerosol generator
US8323683B2 (en) 2005-05-18 2012-12-04 Mcneil-Ppc, Inc. Flavoring of drug-containing chewing gums
EP1901733B1 (en) * 2005-05-23 2016-04-06 President and Fellows of Harvard College Huperzine for use in the treatment of neuropathic pain
EP1998748B1 (en) 2006-03-16 2015-01-14 NicoNovum AB Improved snuff composition
US20070269386A1 (en) * 2006-05-16 2007-11-22 Per Steen New product and use and manufacture thereof
US20070269492A1 (en) * 2006-05-16 2007-11-22 Per Steen New product and use and manufacture thereof
US8642016B2 (en) 2006-07-21 2014-02-04 Jsrnti, Llc Medicinal delivery system, and related methods
EP2114414B1 (en) 2006-12-21 2013-11-06 Trustees Of Tufts College Synthetic lipophilic inositol glycans for treatment of cancer and glucose-metabolism disorders
EP2116264B1 (en) 2006-12-26 2017-09-27 Shin Nippon Biomedical Laboratories, Ltd. Preparation for transnasal application
US20080216828A1 (en) 2007-03-09 2008-09-11 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
US20080286340A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered nicotine containing products
US20080286341A1 (en) * 2007-05-16 2008-11-20 Sven-Borje Andersson Buffered coated nicotine containing products
US8426467B2 (en) 2007-05-22 2013-04-23 Baxter International Inc. Colored esmolol concentrate
US8722736B2 (en) 2007-05-22 2014-05-13 Baxter International Inc. Multi-dose concentrate esmolol with benzyl alcohol
US20110224245A1 (en) * 2008-09-04 2011-09-15 President And Fellows Of Harvard College Treatment Of Neurological Disorders Using Huperzine
US20100124560A1 (en) * 2008-11-14 2010-05-20 Mcneil Ab Multi portion intra-oral dosage form and use thereof
US20100247586A1 (en) * 2009-03-27 2010-09-30 Andreas Hugerth Multi-Portion Intra-Oral Dosage Form With Organoleptic Properties
EP2233134A1 (en) 2009-03-27 2010-09-29 McNeil AB Multi-portion intra-oral dosage form with organoleptic properties
US9101539B2 (en) * 2009-05-15 2015-08-11 Shin Nippon Biomedical Laboratories, Ltd. Intranasal pharmaceutical compositions with improved pharmacokinetics
GB2472327B (en) 2009-07-31 2013-03-13 Shin Nippon Biomedical Lab Ltd Intranasal granisetron and nasal applicator
KR20120130166A (ko) * 2009-12-04 2012-11-29 마글레 홀딩 아베 내생 하전 리간드를 가지는 가수 분해 전분의 미소구체
US20110182831A1 (en) * 2010-01-25 2011-07-28 Aradigm Corporation Systems and methods used in conjunction with nicotine vaccines for effecting cessation of tobacco use
US20110268809A1 (en) 2010-04-28 2011-11-03 Paul Andrew Brinkley Nicotine-Containing Pharmaceutical Compositions
US20110274628A1 (en) 2010-05-07 2011-11-10 Borschke August J Nicotine-containing pharmaceutical compositions
EA201390660A1 (ru) 2010-11-05 2013-11-29 Селекта Байосайенсиз, Инк. Модифицированные никотиновые соединения и связанные способы
US9474303B2 (en) 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9629392B2 (en) 2011-09-22 2017-04-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US20130078307A1 (en) 2011-09-22 2013-03-28 Niconovum Usa, Inc. Nicotine-containing pharmaceutical composition
US9084439B2 (en) 2011-09-22 2015-07-21 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
US9907748B2 (en) 2011-10-21 2018-03-06 Niconovum Usa, Inc. Excipients for nicotine-containing therapeutic compositions
US9763928B2 (en) 2012-02-10 2017-09-19 Niconovum Usa, Inc. Multi-layer nicotine-containing pharmaceutical composition
US20140255452A1 (en) 2013-03-11 2014-09-11 Niconovum Usa, Inc. Method and apparatus for differentiating oral pouch products
EP3021691B1 (en) 2013-07-19 2019-09-04 Altria Client Services LLC Methods and systems for incorporating nicotine into oral products
US20160193188A1 (en) * 2013-08-15 2016-07-07 Antivirus Therapeutics Methods and compositions for increasing the effectiveness of antiviral agents
US20170165252A1 (en) 2015-12-10 2017-06-15 Niconovum Usa Inc. Protein-enriched therapeutic composition
SE541358C2 (en) 2017-05-30 2019-08-13 Enorama Pharma Ab Nicotine-containing chewing gum compositions
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
EP3807260A1 (en) 2018-06-15 2021-04-21 R. J. Reynolds Tobacco Company Purification of nicotine
EP4232006A4 (en) * 2020-12-16 2024-05-08 Liw Innovation Ab NEW POWDER COMPOSITION

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US865026A (en) * 1906-12-15 1907-09-03 Ellis Foster Co Masticable tobacco preparation.
US940521A (en) * 1909-05-06 1909-11-16 George A Endicott Wire-stretching appliance.
US3901248A (en) * 1970-07-22 1975-08-26 Leo Ab Chewable smoking substitute composition
US3877468A (en) * 1970-07-22 1975-04-15 Leo Ab Chewable tobacco substitute composition
US3845217A (en) * 1972-11-16 1974-10-29 Helsingborg L Ab Buffered smoking substitute compositions
SE420565B (sv) * 1974-06-06 1981-10-19 Pharmacia Ab Hjelpmedel for intravaskuler administraring for anvendning i samband med intravaskuler administrering av en losning eller en suspension av ett diagnostiseringsmedel
GB1528391A (en) * 1976-01-05 1978-10-11 Gildemeister V Aerosol compositions
GB2030862A (en) * 1978-04-10 1980-04-16 Smith A A composition for treating drug addiction such as smoking nicotine-containing products
GB8301659D0 (en) * 1983-01-21 1983-02-23 Leo Ab Smoking substitutes
JPS59163313A (ja) * 1983-03-09 1984-09-14 Teijin Ltd 経鼻投与用ペプチドホルモン類組成物
AU587863B2 (en) * 1985-10-07 1989-08-31 Basf Aktiengesellschaft Vitamin-containing granules and production thereof
GB8712176D0 (en) * 1987-05-22 1987-06-24 Cosmas Damian Ltd Drug delivery system
GB8723846D0 (en) * 1987-10-10 1987-11-11 Danbiosyst Ltd Bioadhesive microsphere drug delivery system
US4915950A (en) * 1988-02-12 1990-04-10 Cygnus Research Corporation Printed transdermal drug delivery device
SE8904295D0 (sv) * 1989-12-21 1989-12-21 Pharmacia Ab Smoking substitute
US5026697A (en) * 1990-05-30 1991-06-25 Nda International, Inc. Rapid method for interrupting or attenuating the nicotine/tobacco dependency syndrome
US5167242A (en) * 1990-06-08 1992-12-01 Kabi Pharmacia Aktiebolaq Nicotine-impermeable container and method of fabricating the same
GB9310412D0 (en) * 1993-05-20 1993-07-07 Danbiosyst Uk Nasal nicotine system

Also Published As

Publication number Publication date
AU8118494A (en) 1995-05-23
DK0739206T3 (da) 2001-10-01
WO1995012399A1 (en) 1995-05-11
NZ275903A (en) 1998-01-26
DE69427832D1 (de) 2001-08-30
PT739206E (pt) 2002-01-30
DE69427832T2 (de) 2001-11-22
GR3036964T3 (en) 2002-01-31
US5939100A (en) 1999-08-17
EP0739206B1 (en) 2001-07-25
ES2160689T3 (es) 2001-11-16
AU682228B2 (en) 1997-09-25
ATE203407T1 (de) 2001-08-15
EP0739206A1 (en) 1996-10-30
JPH09504305A (ja) 1997-04-28

Similar Documents

Publication Publication Date Title
SE9303574D0 (sv) Composition for drug delivery and method the manufacturing thereof
MY137348A (en) Highly selective norepinephrine reuptake inhibitors and methods of using the same
FI955583A (sv) Nasal, nicotin innehållande distributionskomposition för läkemedel
FI941770A0 (sv) Effektiverat hudpenetreringssystem för förbättrad lokal administration av läkemedel
IL127244A (en) Substituted amines, methods of their preparation and pharmaceutical compositions containing them
DK1117383T3 (da) Doseringsformer omfattende terapeutisk formulering
MX9703429A (es) Composiciones hermorroidales y metodos de uso.
NO972980D0 (no) Anvendelse av nebivolol som et anti-aterogent middel
UA88270C2 (ru) Фармацевтический препарат и его применение для профилактики удара, диабета
DE69920757D1 (de) Immunsuppressive wirkungen von pteridinderivaten
HUP9801128A2 (hu) Fukopeptidek, eljárás azok előállítására és alkalmazására, valamint ilyen vegyületeket tartalmazó gyógyszerkészítmények
NO972623L (no) Farmasöytisk blanding omfattende lamotrigin
BG104179A (en) Phanquinon administration for the treatment of the alzheimer's disease
BG105342A (en) Optically active pyridyl-4h-1,2,4-oxadiazine derivative and its use in the treatment of vascular diseases
FR2763592B1 (fr) Nouveaux derives glycosyles des ginkgolides, leur application en tant que medicaments et compositions pharmaceutiques les contenant
EA200200914A1 (ru) Система контроля дозирования для однократного ежедневного приема назначенного ципрофлоксацина
BG102707A (en) New triazolopurinpurines, method for their preparation and appplication as medicamentous forms
SE9403905D0 (sv) New formulations
ATE256134T1 (de) Sulfatierte phosphatidylinositole, ihre herstellung und verwendung
CA2221793A1 (en) Novel antibacterial protein
CA2173504A1 (en) Composition for drug delivery comprising nicotine or a derivative thereof and starch microspheres and method for the manufacturing thereof
HUP9701284A2 (hu) 2,3-Benzodiazepin-származékok felhasználása az endogén opioid rendszerrel összefüggő betegségek és állapotok kezelésére, és megelőzésére alkalmas gyógyászati készítmények előállítására
PT986390E (pt) Composicoes farmaceuticas que contem cicloridrato de cinchonina
TH25619A (th) ยาเม็ดวาลาซิโคลเวอร์ที่มีคอลลอยด์ซิลิกอนไดออกไซด์
CA2532330A1 (en) Highly selective norepinephrine reuptake inhibitors and methods of using the same