ATE397458T1 - Neue heilmittel für krebs - Google Patents

Neue heilmittel für krebs

Info

Publication number
ATE397458T1
ATE397458T1 AT01954360T AT01954360T ATE397458T1 AT E397458 T1 ATE397458 T1 AT E397458T1 AT 01954360 T AT01954360 T AT 01954360T AT 01954360 T AT01954360 T AT 01954360T AT E397458 T1 ATE397458 T1 AT E397458T1
Authority
AT
Austria
Prior art keywords
cancer
new cure
cure
new
medicament
Prior art date
Application number
AT01954360T
Other languages
English (en)
Inventor
Toshihiro Noguchi
Akemi Baba
Mitsuharu Hanada
Original Assignee
Dainippon Sumitomo Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Sumitomo Pharma Co filed Critical Dainippon Sumitomo Pharma Co
Application granted granted Critical
Publication of ATE397458T1 publication Critical patent/ATE397458T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
AT01954360T 2000-07-28 2001-07-26 Neue heilmittel für krebs ATE397458T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2000228239 2000-07-28

Publications (1)

Publication Number Publication Date
ATE397458T1 true ATE397458T1 (de) 2008-06-15

Family

ID=18721568

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01954360T ATE397458T1 (de) 2000-07-28 2001-07-26 Neue heilmittel für krebs

Country Status (13)

Country Link
US (3) US7449181B2 (de)
EP (1) EP1308168B1 (de)
JP (1) JP5117660B2 (de)
KR (1) KR20030019623A (de)
CN (2) CN100581585C (de)
AT (1) ATE397458T1 (de)
AU (1) AU2001276689A1 (de)
CA (1) CA2417255C (de)
DE (1) DE60134324D1 (de)
DK (1) DK1308168T3 (de)
ES (1) ES2307633T3 (de)
TW (1) TWI317285B (de)
WO (1) WO2002009754A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7625859B1 (en) * 2000-02-16 2009-12-01 Oregon Health & Science University HER-2 binding antagonists
US7393823B1 (en) 1999-01-20 2008-07-01 Oregon Health And Science University HER-2 binding antagonists
MXPA02011379A (es) * 2000-05-19 2003-06-06 Genentech Inc Ensayo de deteccion de genes para mejorar la probabilidad de una respuesta efectiva a terapia de cancer con el antagonista erbb.
ES2381408T3 (es) * 2002-03-18 2012-05-28 Dainippon Sumitomo Pharma Co., Ltd. Remedios para el cáncer de pulmón.
FR2844455B1 (fr) * 2002-09-13 2007-12-14 Lab Francais Du Fractionnement Traitement des pathologies echappant a la reponse immune par des anticorps optimises
CA2583230A1 (en) * 2004-10-05 2006-04-20 Oregon Health And Science University Compositions and methods for treating disease
CN100464783C (zh) * 2004-11-22 2009-03-04 山东蓝金生物工程有限公司 一种含抗肿瘤抗生素的抗癌药物组合物
KR20170134771A (ko) 2005-01-21 2017-12-06 제넨테크, 인크. Ｈｅｒ 항체의 고정 용량 투여법
UA95902C2 (ru) 2005-02-23 2011-09-26 Дженентек, Инк. Способ увеличения времени развития заболевания или выживаемости у раковых пациентов
WO2006096861A2 (en) * 2005-03-08 2006-09-14 Genentech, Inc. METHODS FOR IDENTIFYING TUMORS RESPONSIVE TO TREATMENT WITH HER DIMERIZATION INHIBITORS (HDIs)
JP2006316040A (ja) 2005-05-13 2006-11-24 Genentech Inc Ｈｅｒｃｅｐｔｉｎ（登録商標）補助療法
ES2477497T3 (es) 2007-03-02 2014-07-17 Genentech, Inc. Predicción de la respuesta a un inhibidor de la dimerización de HER basado en la expresión de HER3 bajo
EP2171090B1 (de) * 2007-06-08 2013-04-03 Genentech, Inc. Genexpressionsmarker für tumorresistenz gegen behandlung mit her2-inhibitor
US9551033B2 (en) 2007-06-08 2017-01-24 Genentech, Inc. Gene expression markers of tumor resistance to HER2 inhibitor treatment
BRPI0812682A2 (pt) 2008-06-16 2010-06-22 Genentech Inc tratamento de cáncer de mama metastático
US8734795B2 (en) 2008-10-31 2014-05-27 Biogen Idec Ma Inc. Light targeting molecules and uses thereof
UA106070C2 (uk) 2009-03-20 2014-07-25 Дженентек, Інк. Антитіло, що специфічно зв'язується з egfr і her3
JP5705836B2 (ja) 2009-05-29 2015-04-22 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト Ｈｅｒ２を発現する胃癌患者のｈｅｒ２シグナル伝達のためのモジュレーター
SG183333A1 (en) 2010-02-18 2012-09-27 Genentech Inc Neuregulin antagonists and use thereof in treating cancer
WO2011146568A1 (en) 2010-05-19 2011-11-24 Genentech, Inc. Predicting response to a her inhibitor
EP2643353A1 (de) 2010-11-24 2013-10-02 Novartis AG Multispezifische moleküle
EP2655413B1 (de) 2010-12-23 2019-01-16 F.Hoffmann-La Roche Ag Polypeptid-polynukleotid-komplex und verwendung bei der gezielten effektorrest-bereitstellung
EP2744824A1 (de) 2011-08-17 2014-06-25 F.Hoffmann-La Roche Ag Neuregulin-antikörper und verwendungen davon
US9327023B2 (en) 2011-10-25 2016-05-03 The Regents Of The University Of Michigan HER2 targeting agent treatment in non-HER2-amplified cancers having HER2 expressing cancer stem cells
AU2012346540C1 (en) 2011-11-30 2019-07-04 Genentech, Inc. ErbB3 mutations in cancer
WO2013083810A1 (en) 2011-12-09 2013-06-13 F. Hoffmann-La Roche Ag Identification of non-responders to her2 inhibitors
SG11201406079TA (en) 2012-03-27 2014-10-30 Genentech Inc Diagnosis and treatments relating to her3 inhibitors
MX363188B (es) 2012-11-30 2019-03-13 Hoffmann La Roche Identificación de pacientes con necesidad de coterapia del inhibidor de pd-l1.
EP3454863A1 (de) 2016-05-10 2019-03-20 INSERM (Institut National de la Santé et de la Recherche Médicale) Kombinationstherapien zur behandlung von krebs
CN107349426B (zh) * 2017-07-12 2018-03-23 马骥 阿司匹林与曲妥珠单抗联合或协同在肿瘤治疗中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6075473A (ja) * 1983-09-30 1985-04-27 Sumitomo Chem Co Ltd アミノナフタセン誘導体
US5185432A (en) * 1986-02-26 1993-02-09 Oncogen Monoclonal antibodies and antigen for human non-small cell lung carcinoma and other certain human carcinomas
JP3040121B2 (ja) * 1988-01-12 2000-05-08 ジェネンテク，インコーポレイテッド 増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法
US5077220A (en) * 1988-08-26 1991-12-31 John Muir Cancer & Aging Institute Monoclonal antibody specific to a novel glycoprotein antigen on human carcinoma cells
JPH035397A (ja) 1989-05-31 1991-01-11 Toshiba Corp 酸化物結晶薄膜の気相成長方法
JP3005397B2 (ja) 1993-09-06 2000-01-31 関西日本電気ソフトウェア株式会社 デッドロック多発自動回避方式
US5686278A (en) * 1994-03-25 1997-11-11 Indiana University Foundation Methods for enhanced retrovirus-mediated gene transfer
CN1164238A (zh) * 1994-09-12 1997-11-05 国际生物免疫有限公司 抗人结肠癌相关抗原的单克隆抗体及其应用
CZ291386B6 (cs) * 1996-02-13 2003-02-12 Zeneca Limited Chinazolinové deriváty jako inhibitory VEGF, způsob jejich přípravy a farmaceutický prostředek, který je obsahuje
CN1082187C (zh) * 1996-11-26 2002-04-03 北京市肿瘤防治研究所 一种检测***受体水平的生物试剂及免疫组化方法
JP2002514201A (ja) * 1997-01-22 2002-05-14 ボード オブ リージェンツ，ザ ユニバーシティ オブ テキサス システム 凝固および腫瘍の処置のための組織因子の方法および組成物
US20030068318A1 (en) * 2001-09-28 2003-04-10 O'brien Timothy Treatment of uterine serous papillary cancer

Also Published As

Publication number Publication date
TWI317285B (en) 2009-11-21
JP5117660B2 (ja) 2013-01-16
US7449181B2 (en) 2008-11-11
CN100581585C (zh) 2010-01-20
US9139658B2 (en) 2015-09-22
AU2001276689A1 (en) 2002-02-13
CN1466464A (zh) 2004-01-07
DK1308168T3 (da) 2008-07-28
US20080031881A1 (en) 2008-02-07
CN101732333B (zh) 2012-08-15
US7879327B2 (en) 2011-02-01
CA2417255C (en) 2011-08-02
CA2417255A1 (en) 2003-01-24
US20110104160A1 (en) 2011-05-05
ES2307633T3 (es) 2008-12-01
EP1308168B1 (de) 2008-06-04
US20030157097A1 (en) 2003-08-21
DE60134324D1 (de) 2008-07-17
WO2002009754A1 (fr) 2002-02-07
EP1308168A1 (de) 2003-05-07
EP1308168A4 (de) 2004-09-01
KR20030019623A (ko) 2003-03-06
CN101732333A (zh) 2010-06-16

Similar Documents

Publication Publication Date Title
ATE397458T1 (de) Neue heilmittel für krebs
PT1196172E (pt) (s,s)-reboxetina para tratar a dor cronica
CY1119029T1 (el) Θεραπευτικη αντιμετωπιση συμπαγων εγκεφαλικων νεοπλασιων με ενα παραγωγο ραπαμυκινης
DE60121988D1 (de) Kombinationstherapie mit antidiabetischen und antikonvulsiven mitteln
AR027355A1 (es) Acidos tiazolidincarboxilicos
BR0012196A (pt) Método de tratamento de um tumor em mamìferos através do uso de conjugados de maitansinóide e anticorpo receptor anti-erbb e artigo industrializado
DK0740650T3 (da) Codrugs som metode til styret transport af lægemiddel
IT1317735B1 (it) Sali di agenti antimicrobici.
DK1525177T3 (da) Substituerede 1,3-diphenylprop-2-en-1-on-derivater, fremstilling og anvendelse deraf
MXPA03006093A (es) Derivados de n(fenilsulfonil)glicina y su uso terapeutico.
PT1244650E (pt) Derivados arilaminas e sua aplicacao como agentes anti-telomerase
PT1401841E (pt) Derivados substituidos de 1-oxa-2,8-diaza-espiro[4.5]dec-2-eno como medicamentos para o tratamento da dor
ES2156603T3 (es) Medicamentos a base de una mezcla sinergetica de metronidazol y de clindamicina.
GB0019283D0 (en) Organic compounds
EE04752B1 (et) Monoklonaalne antikeha, seda tootev hübridoom ja antikeha kasutamine
ATE430586T1 (de) Pegyliertes liposomales doxorubicin in kombination mit ecteinescidin 743
BRPI0418589A (pt) composições farmacêuticas e métodos para tratamento por insulina
DK1465625T3 (da) Opløste topoisomerase-gifte
GB0008305D0 (en) Treatment of fungal infections
NO20053339D0 (no) Levalbuterolsalt.
EP1354896A4 (de) Neuer monoklonaler antikörper
CY1105142T1 (el) Χρηση υποκατεστημενων ενωσεων 6-διμεθυλαμινομεθυλο-1-φαινυλο-κυκλοεξανιου για τη θepαπεια της ακρατειας ουρων
DE60315288D1 (de) Cyanoguanidin prodrugs
EE200300082A (et) Farmatseutilne kompositsioon urineerimishäire raviks
EE200200605A (et) Asendatud akrüloüüldistamütsiini derivaadi kasutamine ravimi valmistamiseks, mis on ette nähtud glutatiooni kõrge tasemega seotud kasvajate raviks

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1308168

Country of ref document: EP