SG11201406079TA - Diagnosis and treatments relating to her3 inhibitors - Google Patents

Diagnosis and treatments relating to her3 inhibitors

Info

Publication number
SG11201406079TA
SG11201406079TA SG11201406079TA SG11201406079TA SG11201406079TA SG 11201406079T A SG11201406079T A SG 11201406079TA SG 11201406079T A SG11201406079T A SG 11201406079TA SG 11201406079T A SG11201406079T A SG 11201406079TA SG 11201406079T A SG11201406079T A SG 11201406079TA
Authority
SG
Singapore
Prior art keywords
diagnosis
her3 inhibitors
treatments relating
treatments
relating
Prior art date
Application number
SG11201406079TA
Inventor
Lukas Amler
David Shames
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of SG11201406079TA publication Critical patent/SG11201406079TA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
SG11201406079TA 2012-03-27 2013-03-15 Diagnosis and treatments relating to her3 inhibitors SG11201406079TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261616241P 2012-03-27 2012-03-27
PCT/US2013/032076 WO2013148315A1 (en) 2012-03-27 2013-03-15 Diagnosis and treatments relating to her3 inhibitors

Publications (1)

Publication Number Publication Date
SG11201406079TA true SG11201406079TA (en) 2014-10-30

Family

ID=48045754

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201406079TA SG11201406079TA (en) 2012-03-27 2013-03-15 Diagnosis and treatments relating to her3 inhibitors

Country Status (13)

Country Link
US (1) US20130259867A1 (en)
EP (1) EP2831115A1 (en)
JP (1) JP2015514710A (en)
KR (1) KR20140148388A (en)
CN (1) CN104220457A (en)
AU (1) AU2013240261A1 (en)
BR (1) BR112014024017A8 (en)
CA (1) CA2865082A1 (en)
HK (1) HK1205143A1 (en)
MX (1) MX2014011500A (en)
RU (1) RU2014136886A (en)
SG (1) SG11201406079TA (en)
WO (1) WO2013148315A1 (en)

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BR112015005369A2 (en) * 2012-09-17 2017-08-08 Hoffmann La Roche usp30 inhibitors and methods for their use
EP2970494B1 (en) * 2013-03-14 2017-12-13 The Board of Regents of The University of Texas System Her3 specific monoclonal antibodies for diagnostic and therapeutic use
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WO2015130173A1 (en) 2014-02-28 2015-09-03 Merus B.V. Antibody that binds erbb-2 and erbb-3
AU2015223566B2 (en) * 2014-02-28 2020-10-08 Merus N.V. Antibodies that bind EGFR and ErbB3
KR20230149328A (en) * 2014-12-22 2023-10-26 시스트이뮨, 인코포레이티드 Bispecific tetravalent antibodies and methods of making and using thereof
EP3283111A4 (en) * 2015-04-17 2019-04-17 Celldex Therapeutics, Inc. Biomarkers related to treatment of cancer with her3 and egfr inhibitors
US10184006B2 (en) 2015-06-04 2019-01-22 Merrimack Pharmaceuticals, Inc. Biomarkers for predicting outcomes of cancer therapy with ErbB3 inhibitors
SG11201803359VA (en) 2015-10-23 2018-05-30 Merus Nv Binding molecules that inhibit cancer growth
CN108602890A (en) 2015-12-11 2018-09-28 瑞泽恩制药公司 Method for reducing or preventing the tumour growth resistant to EGFR and/or ERBB3 retarding agents
WO2018182422A1 (en) 2017-03-31 2018-10-04 Merus N.V. Erbb-2 and erbb3 binding bispecific antibodies for use in the treatment f cells that have an nrg1 fusion gene
SG11202001050PA (en) 2017-08-09 2020-03-30 Merus Nv Antibodies that bind egfr and cmet
JP7072792B2 (en) * 2017-12-11 2022-05-23 国立大学法人神戸大学 Bispecific antibody
GB201913079D0 (en) * 2019-09-11 2019-10-23 Hummingbird Bioscience Holdings Pte Ltd Treatment and prevention of cancer using her3 antigen-binding molecules
EP4352095A2 (en) * 2021-05-30 2024-04-17 Biolojic Design Ltd. Engineered dual binding antibodies and uses thereof

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