ATE274521T1 - Steroidnitrate zur behandlung von oxidativen schädigungen und endothelialer dysfunktion - Google Patents
Steroidnitrate zur behandlung von oxidativen schädigungen und endothelialer dysfunktionInfo
- Publication number
- ATE274521T1 ATE274521T1 AT00917075T AT00917075T ATE274521T1 AT E274521 T1 ATE274521 T1 AT E274521T1 AT 00917075 T AT00917075 T AT 00917075T AT 00917075 T AT00917075 T AT 00917075T AT E274521 T1 ATE274521 T1 AT E274521T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- nitrates
- steroid
- oxidative damage
- endothelial dysfunction
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Biochemistry (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Toxicology (AREA)
- Vascular Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1999MI000751A IT1311922B1 (it) | 1999-04-13 | 1999-04-13 | Composti farmaceutici. |
PCT/EP2000/003238 WO2000061604A2 (en) | 1999-04-13 | 2000-04-11 | Pharmaceutical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE274521T1 true ATE274521T1 (de) | 2004-09-15 |
Family
ID=11382683
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00917075T ATE274521T1 (de) | 1999-04-13 | 2000-04-11 | Steroidnitrate zur behandlung von oxidativen schädigungen und endothelialer dysfunktion |
Country Status (25)
Country | Link |
---|---|
US (3) | US6909007B1 (de) |
EP (2) | EP1475386A3 (de) |
JP (1) | JP2002542162A (de) |
KR (2) | KR100744701B1 (de) |
CN (2) | CN1916013A (de) |
AT (1) | ATE274521T1 (de) |
AU (2) | AU766798B2 (de) |
BR (1) | BR0009696A (de) |
CA (2) | CA2586538C (de) |
DE (1) | DE60013266T2 (de) |
DK (1) | DK1169337T3 (de) |
ES (1) | ES2226805T3 (de) |
HU (1) | HUP0201872A3 (de) |
IL (2) | IL145633A0 (de) |
IT (1) | IT1311922B1 (de) |
MX (1) | MXPA01010212A (de) |
NO (2) | NO323374B1 (de) |
NZ (1) | NZ514572A (de) |
PL (1) | PL199579B1 (de) |
PT (1) | PT1169337E (de) |
RU (1) | RU2240325C2 (de) |
SI (1) | SI1169337T1 (de) |
TR (2) | TR200102929T2 (de) |
WO (1) | WO2000061604A2 (de) |
ZA (1) | ZA200108124B (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001045703A1 (en) | 1999-12-23 | 2001-06-28 | Nitromed, Inc. | Nitrosated and nitrosylated cyclooxygenase-2 inhibitors, compositions and methods of use |
CA2432642A1 (en) | 2000-12-21 | 2002-08-08 | Subhash P. Khanapure | Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use |
IT1320176B1 (it) * | 2000-12-22 | 2003-11-26 | Nicox Sa | Dispersioni solide di principi attivi nitrati. |
EP1219306A1 (de) * | 2000-12-29 | 2002-07-03 | Nicox S.A. | Zyklodextrin und NO-abgebende Arzneimittlen enthaltende Zusammensetzungen |
US6696592B2 (en) | 2001-05-22 | 2004-02-24 | Nicox-S.A. | Methods of making 21-[4′-(nitrooxyalkyl)benzoate] corticosteroid derivatives and intermediates useful in the synthesis thereof |
ITMI20011307A1 (it) * | 2001-06-21 | 2002-12-21 | Nicox Sa | Farmaci per l'epilessia |
ITMI20020148A1 (it) | 2002-01-29 | 2003-07-29 | Nicox Sa | Nuovi corticosteroidi |
ITMI20021025A1 (it) * | 2002-05-14 | 2003-11-14 | Nicox Sa | Farmaci per il trattamento acuto di disfunzioni del circolo venoso epatico e portale |
WO2003103602A2 (en) | 2002-06-11 | 2003-12-18 | Nitromed, Inc. | Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use |
AU2003247792B2 (en) | 2002-07-03 | 2009-09-24 | Nicox S.A. | Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use |
US7244753B2 (en) | 2002-07-29 | 2007-07-17 | Nitromed, Inc. | Cyclooxygenase-2 selective inhibitors, compositions and methods of use |
CN100513415C (zh) * | 2005-08-03 | 2009-07-15 | 中国人民解放军军事医学科学院毒物药物研究所 | 胆汁酸衍生物及其医药用途 |
AU2006286838C1 (en) | 2005-09-02 | 2013-05-02 | Ferrer Internacional S.A. | Nitrooxy derivatives of glucocorticoids |
US8802726B2 (en) | 2006-02-03 | 2014-08-12 | Nicox S.A. | Use of nitrooxyderivative of drug for the treatment of muscular dystrophies |
US7645749B2 (en) * | 2006-04-03 | 2010-01-12 | Forbes Medi-Tech Inc. | Sterol/stanol nitroderivatives and use thereof |
US7645748B2 (en) * | 2006-04-03 | 2010-01-12 | Forbes Medi-Tech Inc. | Sterol/stanol phosphorylnitroderivatives and use thereof |
EP2109617A1 (de) | 2007-02-05 | 2009-10-21 | Nicox S.A. | Steroide zur freisetzung von stickoxid |
WO2009037584A2 (en) * | 2007-08-10 | 2009-03-26 | Topigen Pharmaceuticals Inc. | Combination of nitroderivatized steroid and bronchodilator for treating respiratory disease |
WO2009071990A2 (en) * | 2007-08-31 | 2009-06-11 | Topigen Pharmaceuticals Inc. | No-donating cordicosteroid with improved pharmacokinetic, anti-inflammatory and vasodilatory properties |
AU2008311824A1 (en) * | 2007-10-19 | 2009-04-23 | Burnham Institute For Medical Research | Inhibitors of anti-apoptotic proteins |
CA2731520A1 (en) | 2008-08-05 | 2010-02-11 | Nicox S.A. | New no-releasing steroids for the treatment of retina and macula lutea diseases |
MX2012012225A (es) | 2010-04-23 | 2013-08-27 | Piramal Entpr Ltd | Profármacos de agentes tearapéuticos de liberación de óxido nítrico. |
CU20110244A7 (es) | 2011-12-27 | 2013-08-29 | Ct De Investigación Y Desarrollo De Medicamentos Cidem | Sistemas espiroesteroidales con efectos neuroactivos y anti-inflamatorios |
WO2014111957A1 (en) | 2013-01-21 | 2014-07-24 | Apparao Satyam | Nitric oxide releasing prodrugs of therapeutic agents |
KR101711513B1 (ko) * | 2015-06-26 | 2017-03-02 | 주식회사 엘지생활건강 | 피부 개선용 조성물 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2077750B1 (de) | 1970-02-11 | 1973-03-16 | Clin Byla Ets | |
GB1458372A (en) | 1973-03-05 | 1976-12-15 | Leo Ab | Steroid carbamates and allophanates |
JPS5845724A (ja) | 1981-09-11 | 1983-03-17 | Oriza Yuka Kk | オリザノ−ル乳化液の製造法 |
FR2600653B1 (fr) | 1986-06-24 | 1988-12-16 | Pasteur Strasbourg Universite | Composes de synthese associative d'acides amines soufres ou non soufres avec des derives du d-4 pregnene 3,20-dione ou avec des derives du d-1,4 pregnadiene 3,20-dione aux proprietes glucocorticoides et anti-inflammatoires, procedes d'obtention, compositions pharmaceutiques les contenant. proprietes pharmacologiques et applications |
IT1204571B (it) * | 1987-05-08 | 1989-03-10 | Chiesi Farma Spa | Esteri di 1,4:3,6-dianidrosorbitolo-2-mononitrato e 5-mononitrato,loro procedimento di preparazione e loro composizioni farmaceutiche |
ATE212052T1 (de) * | 1987-06-29 | 2002-02-15 | Massachusetts Inst Technology | Nucleotidsequenz für acetoacetyl-coa reduktase kodierend und verfahren zur herstellung von polyester-biopolymeren |
DE4000397A1 (de) | 1990-01-09 | 1991-07-11 | Hoechst Ag | Lipidselektive antioxidantien sowie deren herstellung und verwendung |
JPH04273892A (ja) | 1991-02-27 | 1992-09-30 | Kao Corp | 新規な21−置換ステロイド化合物 |
JP3108474B2 (ja) | 1991-08-07 | 2000-11-13 | 日清製粉株式会社 | 活性型ビタミンd誘導体 |
DE69214617T2 (de) | 1991-12-26 | 1997-05-28 | Wisconsin Alumni Res Found | 26,27-Dimethylen-1-Alpha, 25-Dihydroxyvitamin-D2 und 26,27-Dihydroxyvitamin-D2 und Verfahren zu ihrer Herstellung |
EP0562497A1 (de) | 1992-03-27 | 1993-09-29 | Nisshin Flour Milling Co., Ltd. | 1-Alpha-Hydroxy-Vitamine D7 und D4', Verfahren zur ihren Herstellung und pharmazeutische Präparate davon |
US5194431A (en) | 1992-07-08 | 1993-03-16 | Wisconsin Alumni Research Foundation | 24-cyclopropane vitamin D derivatives |
US5707984A (en) | 1995-12-08 | 1998-01-13 | G. D. Searle & Co. | Steroid nitrite/nitrate ester derivatives useful as anti-inflammatory drugs |
US5837698A (en) | 1996-05-02 | 1998-11-17 | G. D. Searle & Co. | Steroid nitrite and nitrate ester derivatives useful as anti-inflammatory drugs |
US5985862A (en) * | 1996-05-02 | 1999-11-16 | G.D. Searle & Co. | Pharmaceutical compositions having steroid nitrate ester derivatives useful as anti-inflammatory drugs |
DE19634793A1 (de) | 1996-08-29 | 1998-03-05 | Sanol Arznei Schwarz Gmbh | S- und O-Nitratoacylverbindungen |
IT1285770B1 (it) * | 1996-10-04 | 1998-06-18 | Nicox Sa | Composti corticoidei |
-
1999
- 1999-04-13 IT IT1999MI000751A patent/IT1311922B1/it active
-
2000
- 2000-04-11 PT PT00917075T patent/PT1169337E/pt unknown
- 2000-04-11 CN CNA2006101516855A patent/CN1916013A/zh active Pending
- 2000-04-11 CA CA2586538A patent/CA2586538C/en not_active Expired - Fee Related
- 2000-04-11 HU HU0201872A patent/HUP0201872A3/hu unknown
- 2000-04-11 IL IL14563300A patent/IL145633A0/xx active IP Right Grant
- 2000-04-11 KR KR1020067024049A patent/KR100744701B1/ko not_active IP Right Cessation
- 2000-04-11 CA CA002370446A patent/CA2370446C/en not_active Expired - Fee Related
- 2000-04-11 MX MXPA01010212A patent/MXPA01010212A/es active IP Right Grant
- 2000-04-11 KR KR1020017012940A patent/KR100687821B1/ko not_active IP Right Cessation
- 2000-04-11 JP JP2000611546A patent/JP2002542162A/ja active Pending
- 2000-04-11 CN CNB008087741A patent/CN1296380C/zh not_active Expired - Fee Related
- 2000-04-11 SI SI200030523T patent/SI1169337T1/xx unknown
- 2000-04-11 WO PCT/EP2000/003238 patent/WO2000061604A2/en active IP Right Grant
- 2000-04-11 EP EP04102751A patent/EP1475386A3/de not_active Withdrawn
- 2000-04-11 PL PL350775A patent/PL199579B1/pl unknown
- 2000-04-11 DE DE60013266T patent/DE60013266T2/de not_active Expired - Lifetime
- 2000-04-11 EP EP00917075A patent/EP1169337B1/de not_active Expired - Lifetime
- 2000-04-11 BR BR0009696-2A patent/BR0009696A/pt not_active IP Right Cessation
- 2000-04-11 TR TR2001/02929T patent/TR200102929T2/xx unknown
- 2000-04-11 NZ NZ514572A patent/NZ514572A/xx unknown
- 2000-04-11 ES ES00917075T patent/ES2226805T3/es not_active Expired - Lifetime
- 2000-04-11 AT AT00917075T patent/ATE274521T1/de not_active IP Right Cessation
- 2000-04-11 DK DK00917075T patent/DK1169337T3/da active
- 2000-04-11 US US09/926,327 patent/US6909007B1/en not_active Expired - Fee Related
- 2000-04-11 TR TR2002/01899T patent/TR200201899T2/xx unknown
- 2000-04-11 RU RU2001127575/04A patent/RU2240325C2/ru not_active IP Right Cessation
- 2000-04-11 AU AU38201/00A patent/AU766798B2/en not_active Ceased
-
2001
- 2001-10-03 ZA ZA200108124A patent/ZA200108124B/xx unknown
- 2001-10-10 NO NO20014925A patent/NO323374B1/no unknown
-
2004
- 2004-01-22 AU AU2004200263A patent/AU2004200263B2/en not_active Ceased
-
2005
- 2005-01-04 US US11/028,198 patent/US7186708B2/en not_active Expired - Fee Related
-
2006
- 2006-05-02 IL IL175398A patent/IL175398A0/en unknown
- 2006-12-13 NO NO20065784A patent/NO20065784L/no not_active Application Discontinuation
- 2006-12-22 US US11/643,887 patent/US7524836B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE274521T1 (de) | Steroidnitrate zur behandlung von oxidativen schädigungen und endothelialer dysfunktion | |
DE60019556D1 (de) | 2-amino-benzoxazinonderivate zur behandlung von fettleibigkeit | |
DE60019555D1 (de) | 2-oxy-benzoxazinonderivate zur behandlung von fettleibigkeit | |
ATE271385T1 (de) | Verwendung von cyclooxygenase-2 inhibitoren zur behandlung und verbeugung von neoplasia | |
DE60011570D1 (de) | Arylpiperazinyl-cyclohexyl indolderivate zur behandlung von depressionen | |
DE60124302D1 (de) | Thiazolderivate zur behandlung von ppar-lierte krankheiten | |
ATE300597T1 (de) | Behandlung von geweben | |
DE60019158D1 (de) | Neue oxabispidin-verbindungen zur behandlung von herzarrhythmien | |
DE60027913D1 (de) | 5-beta-sapogenin und pseudosapogeninderivate und ihre verwendung zur behandlung von demenz | |
ATE254913T1 (de) | Diacerein zur behandlung von psoriasis | |
DE60231969D1 (de) | sPLA2-INHIBITOREN ZUR BEHANDLUNG VON ARTERIOSKLEROSE | |
DE60001255T2 (de) | Zusammensetzung zur Behandlung von Polyesterfaser | |
ATE289196T1 (de) | Verwendung von pleuromutilinderivaten zur transdermalen behandlung bakterieller erkrankungen | |
DE60021252D1 (de) | Antikonvulsiva zur behandlung von autismus | |
ATE230741T1 (de) | 3-tetrahydropyridin-4-yl-indole zur behandlung von psychotischen störungen | |
DE60021521D1 (de) | Isonipecotamide zur behandlung von integrin vermittelten störungen | |
DE60005154D1 (de) | S-nitrosothiole als agentien zur behandlung von fehlfunktionen des kreislaufs | |
DE59904564D1 (de) | Verwendung von acetylcholinesterase-inhibitoren zur behandlung von delirien | |
ES2185154T3 (es) | Metodo de uso de inhibidores de la ciclooxigenasa-2 en el tratamiento y prevencion de la demencia. | |
ATE292970T1 (de) | Topische zusammensetzung enthaltend brucin und ihre verwendung zur behandlung von hautschäden | |
ATE259809T1 (de) | Bispidin-derivate zur behandlung von herzarrhythmien | |
DE60034580D1 (de) | Peptid zur behandlung von nervenerkrankungen | |
DE60016934D1 (de) | Thrombopoietin zur behandlung von neurologischen schäden | |
DE69833655D1 (de) | Methoden und zusammensetzungen zur behandlung der hyperlipidämie |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1169337 Country of ref document: EP |
|
REN | Ceased due to non-payment of the annual fee |