ATE141166T1 - Guanidinaminoglycosid enthaltende liposome - Google Patents
Guanidinaminoglycosid enthaltende liposomeInfo
- Publication number
- ATE141166T1 ATE141166T1 AT92106331T AT92106331T ATE141166T1 AT E141166 T1 ATE141166 T1 AT E141166T1 AT 92106331 T AT92106331 T AT 92106331T AT 92106331 T AT92106331 T AT 92106331T AT E141166 T1 ATE141166 T1 AT E141166T1
- Authority
- AT
- Austria
- Prior art keywords
- minoglycoside
- liposomes containing
- containing guanidine
- aminoglycoside
- liposomes
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2242—Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US94639186A | 1986-12-23 | 1986-12-23 | |
US94639886A | 1986-12-23 | 1986-12-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE141166T1 true ATE141166T1 (de) | 1996-08-15 |
Family
ID=27130236
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT87901176T ATE87503T1 (de) | 1986-12-23 | 1987-01-13 | Liposomes praeparat und antibiotikum. |
AT92106331T ATE141166T1 (de) | 1986-12-23 | 1987-01-13 | Guanidinaminoglycosid enthaltende liposome |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT87901176T ATE87503T1 (de) | 1986-12-23 | 1987-01-13 | Liposomes praeparat und antibiotikum. |
Country Status (8)
Country | Link |
---|---|
EP (3) | EP0498471B1 (de) |
JP (1) | JP2528153B2 (de) |
AT (2) | ATE87503T1 (de) |
AU (1) | AU609711B2 (de) |
CA (1) | CA1314481C (de) |
DE (3) | DE3785198T3 (de) |
IL (2) | IL97538A (de) |
WO (1) | WO1988004573A1 (de) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4920016A (en) * | 1986-12-24 | 1990-04-24 | Linear Technology, Inc. | Liposomes with enhanced circulation time |
IL90561A (en) * | 1988-06-08 | 1993-08-18 | Fountain Pharm Inc | Method for making solvent dilution microcarriers |
US5269979A (en) * | 1988-06-08 | 1993-12-14 | Fountain Pharmaceuticals, Inc. | Method for making solvent dilution microcarriers |
BE1001869A3 (fr) * | 1988-10-12 | 1990-04-03 | Franz Legros | Procede d'encapsulation liposomiale d'antibiotiques aminoglucosidiques, en particulier de la gentamycine. |
US5843473A (en) * | 1989-10-20 | 1998-12-01 | Sequus Pharmaceuticals, Inc. | Method of treatment of infected tissues |
US6060080A (en) * | 1990-07-16 | 2000-05-09 | Daiichi Pharmaceutical Co., Ltd. | Liposomal products |
CA2046997C (en) * | 1990-07-16 | 2000-12-12 | Hiroshi Kikuchi | Liposomal products |
PT100486B (pt) * | 1992-05-14 | 1999-07-30 | Ineti Inst Nac Engenh E Tecnol | Aminoglucosidos lipossomais com altas eficacia de encapsulacao e actividade terapeutica, nomeadamente a netilmicina, e processo para a sua preparcao |
WO1994012155A1 (en) * | 1992-12-02 | 1994-06-09 | Vestar, Inc. | Antibiotic formulation and process |
US5958449A (en) | 1992-12-02 | 1999-09-28 | Nexstar Pharmaceuticals, Inc. | Antibiotic formulation and use for bacterial infections |
CN1040177C (zh) * | 1993-04-23 | 1998-10-14 | 江苏省微生物研究所 | 一种含1-N-乙基庆大霉素C1a或其盐的药用制剂及制备方法 |
US5759571A (en) * | 1993-05-11 | 1998-06-02 | Nexstar Pharmaceuticals, Inc. | Antibiotic formulation and use for drug resistant infections |
PT729351E (pt) * | 1993-11-16 | 2000-12-29 | Skyepharma Inc | Vesiculas com libertacao controlada de activos |
US6613352B2 (en) | 1999-04-13 | 2003-09-02 | Universite De Montreal | Low-rigidity liposomal formulation |
EP1404297B1 (de) | 2001-06-12 | 2011-04-27 | The Johns Hopkins University School Of Medicine | Reservoirvorrichtung für die intraokulare arzneimittelabgabe |
US20050085432A1 (en) * | 2001-12-26 | 2005-04-21 | Aviva Lapidot | Methods of using conjugates of saccharides and acetamidino or guanidino compounds for treating bacterial infections |
US7544369B2 (en) * | 2002-10-29 | 2009-06-09 | Transave, Inc. | Sustained release of antiinfectives |
US7718189B2 (en) | 2002-10-29 | 2010-05-18 | Transave, Inc. | Sustained release of antiinfectives |
CA2896083A1 (en) | 2005-12-08 | 2007-06-14 | Insmed Incorporated | Lipid-based compositions of antiinfectives for treating pulmonary infections and methods of use thereof |
WO2008137717A1 (en) | 2007-05-04 | 2008-11-13 | Transave, Inc. | Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof |
US9114081B2 (en) | 2007-05-07 | 2015-08-25 | Insmed Incorporated | Methods of treating pulmonary disorders with liposomal amikacin formulations |
US9119783B2 (en) | 2007-05-07 | 2015-09-01 | Insmed Incorporated | Method of treating pulmonary disorders with liposomal amikacin formulations |
US9333214B2 (en) | 2007-05-07 | 2016-05-10 | Insmed Incorporated | Method for treating pulmonary disorders with liposomal amikacin formulations |
WO2010088548A1 (en) | 2009-01-29 | 2010-08-05 | Forsight Labs, Llc | Posterior segment drug delivery |
US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
WO2012019139A1 (en) | 2010-08-05 | 2012-02-09 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
EP3861969A1 (de) | 2010-08-05 | 2021-08-11 | ForSight Vision4, Inc. | Injektorvorrichtung zur arzneimittelabgabe |
SI2600812T1 (sl) | 2010-08-05 | 2021-12-31 | ForSight Vision4, Inc., | Naprava za zdravljenje očesa |
US20140031769A1 (en) | 2010-11-19 | 2014-01-30 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
EP4249059A3 (de) | 2011-06-28 | 2023-11-29 | ForSight Vision4, Inc. | Vorrichtung zum sammeln einer flüssigkeitsprobe aus einer reservoirkammer einer therapeutischen vorrichtung für das auge |
EP2739252A4 (de) | 2011-08-05 | 2015-08-12 | Forsight Vision4 Inc | Abgabe kleiner moleküle über eine implantierbare therapeutische vorrichtung |
LT2755600T (lt) | 2011-09-16 | 2021-04-26 | Forsight Vision4, Inc. | Skysčio pakeitimo aparatas |
WO2013116061A1 (en) | 2012-02-03 | 2013-08-08 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
JP6402097B2 (ja) | 2012-05-21 | 2018-10-10 | インスメッド インコーポレイテッド | 肺感染症を処置するためのシステム |
RU2018135921A (ru) | 2012-11-29 | 2019-02-05 | Инсмед Инкорпорейтед | Стабилизированные составы ванкомицина |
EP2968113B8 (de) | 2013-03-14 | 2020-10-28 | Forsight Vision4, Inc. | Systeme zur verzögerten intraokularen abgabe schwerlöslicher verbindungen aus einem implantat mit einem portabgabesystem |
CA2907681C (en) | 2013-03-28 | 2022-11-22 | Forsight Vision4, Inc. | Ophthalmic implant for delivering therapeutic substances |
BR112016026699B1 (pt) | 2014-05-15 | 2022-09-13 | Insmed Incorporated | Uso de uma composição farmaceutica de amicacina ou de um sal farmaceuticamente aceitável desta |
KR102416726B1 (ko) | 2014-07-15 | 2022-07-05 | 포사이트 비젼4, 인크. | 안구 이식물 전달 디바이스 및 방법 |
EP3177289A4 (de) | 2014-08-08 | 2018-03-21 | Forsight Vision4, Inc. | Stabile und lösliche formulierungen von rezeptortyrosinkinaseinhibitoren und verfahren zur herstellung davon |
AU2015346450B2 (en) | 2014-11-10 | 2020-01-30 | Forsight Vision4, Inc. | Expandable drug delivery devices and method of use |
EP3377009B1 (de) | 2015-11-20 | 2020-10-28 | ForSight Vision4, Inc. | Poröse strukturen für arzneimittelabgabevorrichtungen mit verlängerter freisetzung |
EP3439591B1 (de) | 2016-04-05 | 2020-09-23 | ForSight Vision4, Inc. | Implantierbare okulare arzneimittelabgabevorrichtungen |
KR20200093581A (ko) | 2017-11-21 | 2020-08-05 | 포사이트 비젼4, 인크. | 확장 가능한 포트 전달 시스템을 위한 유체 교환 기기 및 사용 방법 |
JP7460534B2 (ja) | 2018-03-30 | 2024-04-02 | インスメッド インコーポレイテッド | リポソーム医薬品の連続製造方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3993754A (en) * | 1974-10-09 | 1976-11-23 | The United States Of America As Represented By The United States Energy Research And Development Administration | Liposome-encapsulated actinomycin for cancer chemotherapy |
JPS5186117A (en) * | 1975-01-27 | 1976-07-28 | Tanabe Seiyaku Co | Johoseibiryushiseizainoseiho |
US4086257A (en) * | 1976-10-12 | 1978-04-25 | Sears Barry D | Phosphatidyl quaternary ammonium compounds |
CH624011A5 (de) * | 1977-08-05 | 1981-07-15 | Battelle Memorial Institute | |
US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
US4397846A (en) * | 1981-05-15 | 1983-08-09 | Murray Weiner | Storage-stable lipid vesicles and method of preparation |
JPS59500952A (ja) * | 1982-03-29 | 1984-05-31 | ザ リポソ−ム カンパニ−、インコ−ポレ−テッド | 安定なプルリラメラベシクル類 |
US4522803A (en) * | 1983-02-04 | 1985-06-11 | The Liposome Company, Inc. | Stable plurilamellar vesicles, their preparation and use |
SU1123697A1 (ru) * | 1982-08-18 | 1984-11-15 | Всесоюзный научно-исследовательский институт фармации | Способ получени липосомальной формы антибиотиков стрептомицинового р да |
US4588578A (en) * | 1983-08-08 | 1986-05-13 | The Liposome Company, Inc. | Lipid vesicles prepared in a monophase |
JPS59210013A (ja) * | 1983-05-04 | 1984-11-28 | Ajinomoto Co Inc | 活性物質含有リポソ−ム |
US4515736A (en) * | 1983-05-12 | 1985-05-07 | The Regents Of The University Of California | Method for encapsulating materials into liposomes |
MX160365A (es) * | 1983-08-31 | 1990-02-12 | Rockwell International Corp | Mejoras a metodo para formar un piston de frenado para freno de disco |
US4532089A (en) * | 1984-01-14 | 1985-07-30 | Northwestern University | Method of preparing giant size liposomes |
US4610868A (en) * | 1984-03-20 | 1986-09-09 | The Liposome Company, Inc. | Lipid matrix carriers for use in drug delivery systems |
JPH0655676B2 (ja) * | 1984-07-26 | 1994-07-27 | ザ リポソ−ム カンパニ−、インコ−ポレ−テツド | 脂質小胞体中に含有された抗菌物質の混合物による抗菌活性の増高 |
JPH0680767A (ja) * | 1992-09-03 | 1994-03-22 | Matsushita Electric Ind Co Ltd | 電子・電気機器用エポキシ樹脂組成物 |
-
1987
- 1987-01-13 AT AT87901176T patent/ATE87503T1/de not_active IP Right Cessation
- 1987-01-13 DE DE3785198T patent/DE3785198T3/de not_active Expired - Lifetime
- 1987-01-13 CA CA000527232A patent/CA1314481C/en not_active Expired - Fee Related
- 1987-01-13 DE DE3751871T patent/DE3751871T4/de not_active Expired - Lifetime
- 1987-01-13 IL IL9753887A patent/IL97538A/en not_active IP Right Cessation
- 1987-01-13 AU AU69345/87A patent/AU609711B2/en not_active Ceased
- 1987-01-13 JP JP62501069A patent/JP2528153B2/ja not_active Expired - Fee Related
- 1987-01-13 WO PCT/US1987/000077 patent/WO1988004573A1/en active IP Right Grant
- 1987-01-13 EP EP92106331A patent/EP0498471B1/de not_active Expired - Lifetime
- 1987-01-13 EP EP19920106330 patent/EP0500143A3/en not_active Withdrawn
- 1987-01-13 DE DE3751871A patent/DE3751871D1/de not_active Expired - Fee Related
- 1987-01-13 AT AT92106331T patent/ATE141166T1/de not_active IP Right Cessation
- 1987-01-13 EP EP87901176A patent/EP0295248B2/de not_active Expired - Lifetime
-
1991
- 1991-03-13 IL IL97538A patent/IL97538A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE3785198T3 (de) | 1999-09-02 |
IL97538A0 (en) | 1992-06-21 |
WO1988004573A1 (en) | 1988-06-30 |
EP0295248B1 (de) | 1993-03-31 |
EP0295248B2 (de) | 1999-04-28 |
AU609711B2 (en) | 1991-05-09 |
DE3751871T4 (de) | 1998-03-26 |
CA1314481C (en) | 1993-03-16 |
EP0500143A3 (en) | 1993-03-03 |
EP0500143A2 (de) | 1992-08-26 |
DE3785198D1 (de) | 1993-05-06 |
DE3751871T2 (de) | 1997-03-13 |
IL97538A (en) | 1995-03-15 |
AU6934587A (en) | 1988-07-15 |
JPH01501619A (ja) | 1989-06-08 |
DE3751871D1 (de) | 1996-09-19 |
EP0498471A2 (de) | 1992-08-12 |
ATE87503T1 (de) | 1993-04-15 |
EP0498471B1 (de) | 1996-08-14 |
DE3785198T2 (de) | 1993-07-15 |
EP0295248A1 (de) | 1988-12-21 |
JP2528153B2 (ja) | 1996-08-28 |
EP0295248A4 (de) | 1988-12-19 |
EP0498471A3 (en) | 1993-03-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |