AR108068A1 - Compuestos bicíclicos - Google Patents

Compuestos bicíclicos

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Publication number
AR108068A1
AR108068A1 ARP170100825A ARP170100825A AR108068A1 AR 108068 A1 AR108068 A1 AR 108068A1 AR P170100825 A ARP170100825 A AR P170100825A AR P170100825 A ARP170100825 A AR P170100825A AR 108068 A1 AR108068 A1 AR 108068A1
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AR
Argentina
Prior art keywords
alkyl
alkoxy
substituted
cycloalkyl
unsubstituted
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ARP170100825A
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English (en)
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Basf Se
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Publication of AR108068A1 publication Critical patent/AR108068A1/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P7/00—Arthropodicides
    • A01P7/04—Insecticides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N2300/00—Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Insects & Arthropods (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Catching Or Destruction (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Fodder In General (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Reivindicación 1: Un compuesto de la fórmula (1), en donde el círculo en el anillo significa que el anillo es totalmente insaturado; Y es C=X, en donde X es O ó S; P es N(Rˣ) o C(R³); Q es N(Rʸ) o C(R⁴); siempre que si P es N(Rˣ), Q sea C(R⁴) y si P es C(R³), Q sea N(Rʸ); Rˣ, Rʸ se seleccionan, independientemente entre sí, del grupo que consiste en C₁₋₆-alquilo, C₁₋₆-alcoxi, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₁₋₆-alcoxi-C₁₋₄-alcoxi, C₃₋₆-cicloalquilo, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno, C(O)-ORᵃ, NRᵇRᶜ, C₁₋₆-alquilen-NRᵇRᶜ, O-C₁₋₆-alquilen-NRᵇRᶜ, C₁₋₆-alquilen-CN, NH-C₁₋₆-alquilen-NRᵇRᶜ, C(O)-NRᵇRᶜ, C(O)-Rᵈ, SO₂NRᵇRᶜ, S(=O)ₘRᵉ, fenilo y bencilo, en donde el anillo de fenilo es no sustituido o sustituido con radicales Rᶠ; R¹ es C₁₋₆-alquilo, C₁₋₆-alcoxi, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₃₋₆-cicloalquilo, C₃₋₆-cicloalcoxi, C₁₋₆-sulfenilo, C₁₋₆-sulfinilo o C₁₋₆-sulfonilo, en donde cada uno de los radicales antes mencionados es parcial o totalmente halogenado; R² R³, R⁴ se seleccionan, independientemente entre sí, del grupo que consiste en H, halógeno, N₃, CN, NO₂, -SCN, -SF₅, C₁₋₆-alquilo, C₁₋₆-alcoxi, C₂₋₆-alquenilo, tri-C₁₋₆-alquilsililo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₁₋₆-alcoxi-C₁₋₄-alcoxi, C₃₋₆-cicloalquilo, C₃₋₆-cicloalcoxi, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno, C(O)-ORᵃ, NRᵇRᶜ, C₁₋₆-alquilen-NRᵇRᶜ, O-C₁₋₆-alquilen-NRᵇRᶜ, C₁₋₆-alquilen-CN, NH-C₁₋₆-alquilen-NRᵇRᶜ, C(O)-NRᵇRᶜ, C(O)-Rᵈ, SO₂NRᵇRᶜ y S(=O)ₘRᵉ, un radical también puede ser fenilo, fenoxi, fenilcarbonilo, feniltio o bencilo, en donde el anillo de fenilo es no sustituido o sustituido con radicales Rᶠ; Ar es fenilo o heteroarilo de 5 ó 6 miembros, que son no sustituidos o sustituidos con radicales RAʳ, que son idénticos o diferentes, en donde RAʳ se seleccionan, independientemente entre sí, del grupo que consiste en halógeno, N₃, OH, CN, NO₂, -SCN, -SF₅, C₁₋₆-alquilo, C₁₋₆-alcoxi, C₂₋₆-alquenilo, tri-C₁₋₆-alquilsililo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₁₋₆-alcoxi-C₁₋₄-alcoxi, C₃₋₆-cicloalquilo, C₃₋₆-cicloalcoxi, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno, C(O)-ORᵃ, NRᵇRᶜ, C₁₋₆-alquilen-NRᵇRᶜ, O-C₁₋₆-alquilen-NRᵇRᶜ, C₁₋₆-alquilen-CN, NH-C₁₋₆-alquilen-NRᵇRᶜ, C(O)-NRᵇRᶜ, C(O)-Rᵈ, SO₂NRᵇRᶜ y S(=O)ₘRᵉ, un radical también puede ser fenilo, fenoxi, fenilcarbonilo, feniltio o bencilo, en donde el anillo de fenilo es no sustituido o sustituido con radicales Rᶠ; cada Rᵃ se selecciona de H, C₁₋₆-alquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₃₋₆-cicloalquilo, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno, C₁₋₆-alquilen-NRᵇRᶜ, C₁₋₆-alquilen-CN, fenilo y bencilo, en donde el anillo de fenilo es no sustituido o sustituido con radicales Rᶠ; cada Rᵇ se selecciona de H, C₁₋₆-alquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₃₋₆-cicloalquilo, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno, C₁₋₆-alquilen-CN, fenilo y bencilo, en donde el fenilo es no sustituido o sustituido con radicales Rᶠ; cada Rᶜ se selecciona de H, C₁₋₆-alquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₃₋₆-cicloalquilo, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno, C₁₋₆-alquilen-CN, fenilo y bencilo, en donde el anillo de fenilo es no sustituido o sustituido con radicales Rᶠ; cada porción NRᵇRᶜ también puede formar un heterociclo unido a N, saturado de 5 a 8 miembros, que además del átomo de nitrógeno, puede tener 1 ó 2 heteroátomos adicionales o porciones de heteroátomos seleccionadas de O, S(=O)ₘ y N-R’, en donde R’ es H o C₁₋₆-alquilo y en donde el heterociclo unido a N es no sustituido o sustituido con radicales seleccionados de halógeno, C₁₋₄-alquilo, C₁₋₄-haloalquilo, C₁₋₄-alcoxi y C₁₋₄-haloalcoxi; cada Rᵈ se selecciona de H, C₁₋₆-alquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₃₋₆-cicloalquilo, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno, fenilo y bencilo, en donde el anillo de fenilo es no sustituido o sustituido con radicales Rᶠ; cada Rᵉ se selecciona de C₁₋₆-alquilo, C₃₋₆-cicloalquilo, C₃₋₆-cicloalquil-C₁₋₄ alquilo, que son no sustituidos o sustituidos con halógeno, fenilo y bencilo, en donde el anillo de fenilo es no sustituido o sustituido con Rᶠ; cada Rᶠ se selecciona de halógeno, N₃, OH, CN, NO₂, SCN, SF₅, C₁₋₆-alquilo, C₁₋₆-alcoxi, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₁₋₆-alcoxi-C₁₋₄-alcoxi, C₃₋₆-cicloalquilo, C₃₋₆-cicloalcoxi, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno; m es 0, 1 ó 2; y los N-óxidos, estereoisómeros, tautómeros y las sales aceptables en la agricultura o veterinaria de aquel.
ARP170100825A 2016-04-01 2017-03-31 Compuestos bicíclicos AR108068A1 (es)

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IN201621011658 2016-04-01

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US (1) US11570992B2 (es)
EP (1) EP3436457B1 (es)
JP (1) JP7027329B2 (es)
KR (1) KR102411744B1 (es)
CN (1) CN108779121A (es)
AR (1) AR108068A1 (es)
AU (2) AU2017242539B2 (es)
BR (1) BR112018068851B1 (es)
CA (1) CA3015934A1 (es)
CL (1) CL2018002794A1 (es)
CO (1) CO2018010715A2 (es)
EA (1) EA038878B1 (es)
ES (1) ES2928005T3 (es)
IL (1) IL261551B (es)
MX (1) MX2018012016A (es)
PE (1) PE20181898A1 (es)
PL (1) PL3436457T3 (es)
UA (1) UA123912C2 (es)
WO (1) WO2017167832A1 (es)

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