AR108068A1 - Compuestos bicíclicos - Google Patents
Compuestos bicíclicosInfo
- Publication number
- AR108068A1 AR108068A1 ARP170100825A ARP170100825A AR108068A1 AR 108068 A1 AR108068 A1 AR 108068A1 AR P170100825 A ARP170100825 A AR P170100825A AR P170100825 A ARP170100825 A AR P170100825A AR 108068 A1 AR108068 A1 AR 108068A1
- Authority
- AR
- Argentina
- Prior art keywords
- alkyl
- alkoxy
- substituted
- cycloalkyl
- unsubstituted
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01P—BIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
- A01P7/00—Arthropodicides
- A01P7/04—Insecticides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/14—Ectoparasiticides, e.g. scabicides
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N2300/00—Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Environmental Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Dentistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Insects & Arthropods (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pretreatment Of Seeds And Plants (AREA)
- Catching Or Destruction (AREA)
- Plural Heterocyclic Compounds (AREA)
- Fodder In General (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Reivindicación 1: Un compuesto de la fórmula (1), en donde el círculo en el anillo significa que el anillo es totalmente insaturado; Y es C=X, en donde X es O ó S; P es N(Rˣ) o C(R³); Q es N(Rʸ) o C(R⁴); siempre que si P es N(Rˣ), Q sea C(R⁴) y si P es C(R³), Q sea N(Rʸ); Rˣ, Rʸ se seleccionan, independientemente entre sí, del grupo que consiste en C₁₋₆-alquilo, C₁₋₆-alcoxi, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₁₋₆-alcoxi-C₁₋₄-alcoxi, C₃₋₆-cicloalquilo, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno, C(O)-ORᵃ, NRᵇRᶜ, C₁₋₆-alquilen-NRᵇRᶜ, O-C₁₋₆-alquilen-NRᵇRᶜ, C₁₋₆-alquilen-CN, NH-C₁₋₆-alquilen-NRᵇRᶜ, C(O)-NRᵇRᶜ, C(O)-Rᵈ, SO₂NRᵇRᶜ, S(=O)ₘRᵉ, fenilo y bencilo, en donde el anillo de fenilo es no sustituido o sustituido con radicales Rᶠ; R¹ es C₁₋₆-alquilo, C₁₋₆-alcoxi, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₃₋₆-cicloalquilo, C₃₋₆-cicloalcoxi, C₁₋₆-sulfenilo, C₁₋₆-sulfinilo o C₁₋₆-sulfonilo, en donde cada uno de los radicales antes mencionados es parcial o totalmente halogenado; R² R³, R⁴ se seleccionan, independientemente entre sí, del grupo que consiste en H, halógeno, N₃, CN, NO₂, -SCN, -SF₅, C₁₋₆-alquilo, C₁₋₆-alcoxi, C₂₋₆-alquenilo, tri-C₁₋₆-alquilsililo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₁₋₆-alcoxi-C₁₋₄-alcoxi, C₃₋₆-cicloalquilo, C₃₋₆-cicloalcoxi, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno, C(O)-ORᵃ, NRᵇRᶜ, C₁₋₆-alquilen-NRᵇRᶜ, O-C₁₋₆-alquilen-NRᵇRᶜ, C₁₋₆-alquilen-CN, NH-C₁₋₆-alquilen-NRᵇRᶜ, C(O)-NRᵇRᶜ, C(O)-Rᵈ, SO₂NRᵇRᶜ y S(=O)ₘRᵉ, un radical también puede ser fenilo, fenoxi, fenilcarbonilo, feniltio o bencilo, en donde el anillo de fenilo es no sustituido o sustituido con radicales Rᶠ; Ar es fenilo o heteroarilo de 5 ó 6 miembros, que son no sustituidos o sustituidos con radicales RAʳ, que son idénticos o diferentes, en donde RAʳ se seleccionan, independientemente entre sí, del grupo que consiste en halógeno, N₃, OH, CN, NO₂, -SCN, -SF₅, C₁₋₆-alquilo, C₁₋₆-alcoxi, C₂₋₆-alquenilo, tri-C₁₋₆-alquilsililo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₁₋₆-alcoxi-C₁₋₄-alcoxi, C₃₋₆-cicloalquilo, C₃₋₆-cicloalcoxi, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno, C(O)-ORᵃ, NRᵇRᶜ, C₁₋₆-alquilen-NRᵇRᶜ, O-C₁₋₆-alquilen-NRᵇRᶜ, C₁₋₆-alquilen-CN, NH-C₁₋₆-alquilen-NRᵇRᶜ, C(O)-NRᵇRᶜ, C(O)-Rᵈ, SO₂NRᵇRᶜ y S(=O)ₘRᵉ, un radical también puede ser fenilo, fenoxi, fenilcarbonilo, feniltio o bencilo, en donde el anillo de fenilo es no sustituido o sustituido con radicales Rᶠ; cada Rᵃ se selecciona de H, C₁₋₆-alquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₃₋₆-cicloalquilo, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno, C₁₋₆-alquilen-NRᵇRᶜ, C₁₋₆-alquilen-CN, fenilo y bencilo, en donde el anillo de fenilo es no sustituido o sustituido con radicales Rᶠ; cada Rᵇ se selecciona de H, C₁₋₆-alquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₃₋₆-cicloalquilo, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno, C₁₋₆-alquilen-CN, fenilo y bencilo, en donde el fenilo es no sustituido o sustituido con radicales Rᶠ; cada Rᶜ se selecciona de H, C₁₋₆-alquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₃₋₆-cicloalquilo, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno, C₁₋₆-alquilen-CN, fenilo y bencilo, en donde el anillo de fenilo es no sustituido o sustituido con radicales Rᶠ; cada porción NRᵇRᶜ también puede formar un heterociclo unido a N, saturado de 5 a 8 miembros, que además del átomo de nitrógeno, puede tener 1 ó 2 heteroátomos adicionales o porciones de heteroátomos seleccionadas de O, S(=O)ₘ y N-R, en donde R es H o C₁₋₆-alquilo y en donde el heterociclo unido a N es no sustituido o sustituido con radicales seleccionados de halógeno, C₁₋₄-alquilo, C₁₋₄-haloalquilo, C₁₋₄-alcoxi y C₁₋₄-haloalcoxi; cada Rᵈ se selecciona de H, C₁₋₆-alquilo, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₃₋₆-cicloalquilo, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno, fenilo y bencilo, en donde el anillo de fenilo es no sustituido o sustituido con radicales Rᶠ; cada Rᵉ se selecciona de C₁₋₆-alquilo, C₃₋₆-cicloalquilo, C₃₋₆-cicloalquil-C₁₋₄ alquilo, que son no sustituidos o sustituidos con halógeno, fenilo y bencilo, en donde el anillo de fenilo es no sustituido o sustituido con Rᶠ; cada Rᶠ se selecciona de halógeno, N₃, OH, CN, NO₂, SCN, SF₅, C₁₋₆-alquilo, C₁₋₆-alcoxi, C₂₋₆-alquenilo, C₂₋₆-alquinilo, C₁₋₆-alcoxi-C₁₋₄-alquilo, C₁₋₆-alcoxi-C₁₋₄-alcoxi, C₃₋₆-cicloalquilo, C₃₋₆-cicloalcoxi, C₃₋₆-cicloalquil-C₁₋₄-alquilo, C₃₋₆-cicloalcoxi-C₁₋₄-alquilo, que son no sustituidos o sustituidos con halógeno; m es 0, 1 ó 2; y los N-óxidos, estereoisómeros, tautómeros y las sales aceptables en la agricultura o veterinaria de aquel.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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IN201621011658 | 2016-04-01 |
Publications (1)
Publication Number | Publication Date |
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AR108068A1 true AR108068A1 (es) | 2018-07-11 |
Family
ID=58448567
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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ARP170100825A AR108068A1 (es) | 2016-04-01 | 2017-03-31 | Compuestos bicíclicos |
Country Status (19)
Country | Link |
---|---|
US (1) | US11570992B2 (es) |
EP (1) | EP3436457B1 (es) |
JP (1) | JP7027329B2 (es) |
KR (1) | KR102411744B1 (es) |
CN (1) | CN108779121A (es) |
AR (1) | AR108068A1 (es) |
AU (2) | AU2017242539B2 (es) |
BR (1) | BR112018068851B1 (es) |
CA (1) | CA3015934A1 (es) |
CL (1) | CL2018002794A1 (es) |
CO (1) | CO2018010715A2 (es) |
EA (1) | EA038878B1 (es) |
ES (1) | ES2928005T3 (es) |
IL (1) | IL261551B (es) |
MX (1) | MX2018012016A (es) |
PE (1) | PE20181898A1 (es) |
PL (1) | PL3436457T3 (es) |
UA (1) | UA123912C2 (es) |
WO (1) | WO2017167832A1 (es) |
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GB201116559D0 (en) | 2011-09-26 | 2011-11-09 | Univ Leuven Kath | Novel viral replication inhibitors |
JOP20160086B1 (ar) | 2015-05-08 | 2021-08-17 | 2 Katholieke Univ Leuven Ku Leuven Research And Development | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
JO3633B1 (ar) | 2015-09-16 | 2020-08-27 | Katholieke Univ Leuven Ku Leuven Research & Development | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
JOP20160198B1 (ar) | 2015-09-16 | 2022-03-14 | Janssen Pharmaceuticals Inc | مشتقات اندول مستبدلة احاديا او ثنائيا بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
EP3436435B1 (en) | 2016-03-31 | 2021-05-12 | Janssen Pharmaceuticals, Inc. | Substituted indole derivatives as dengue viral replication inhibitors |
SG11201808270PA (en) | 2016-03-31 | 2018-10-30 | Janssen Pharmaceuticals Inc | Substituted indoline derivatives as dengue viral replication inhibitors |
JOP20170069B1 (ar) | 2016-04-01 | 2021-08-17 | 1 Janssen Pharmaceuticals Inc | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
MA44502A (fr) | 2016-04-01 | 2019-02-06 | Janssen Pharmaceuticals Inc | Dérivés d'indole substitués utilisés en tant qu'inhibiteurs de réplication du virus de la dengue |
CN109415280A (zh) | 2016-07-07 | 2019-03-01 | 巴斯夫欧洲公司 | 用于制备杀虫环戊烯类化合物的Oxy-Cope重排 |
UA125313C2 (uk) | 2017-03-28 | 2022-02-16 | Басф Се | Пестициди |
JOP20180026A1 (ar) | 2017-03-31 | 2019-01-30 | Univ Leuven Kath | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
JOP20180025B1 (ar) | 2017-03-31 | 2021-08-17 | Janssen Pharmaceuticals Inc | مشتقات اندولين مستبدلة بصفتها مانعات للتكاثر الفيروسي لحمى الفنك |
US11591335B2 (en) * | 2017-05-10 | 2023-02-28 | Basf Se | Bicyclic pesticidal compounds |
KR102625991B1 (ko) | 2017-05-22 | 2024-01-16 | 얀센 파마슈티칼즈, 인코포레이티드 | 뎅기 바이러스 복제 억제제로서의 치환 인돌린 유도체 |
KR102625988B1 (ko) | 2017-05-22 | 2024-01-16 | 얀센 파마슈티칼즈, 인코포레이티드 | 뎅기 바이러스 복제 억제제로서의 치환 인돌린 유도체 |
US11690378B2 (en) | 2017-12-26 | 2023-07-04 | Sumitomo Chemical Company, Limited | Substituted pyridines as noxious arthropod control agents |
EP3765465B1 (de) * | 2018-03-12 | 2022-05-25 | Bayer Aktiengesellschaft | Kondensierte bicyclische heterocyclen-derivate als schädlingsbekämpfungsmittel |
UA127747C2 (uk) | 2018-10-23 | 2023-12-20 | Басф Се | Трициклічні пестицидні сполуки |
AR118243A1 (es) * | 2019-03-07 | 2021-09-22 | Pi Industries Ltd | Compuestos heterocíclicos fusionados y su uso como agentes de control de plagas |
EP4061815B1 (en) | 2019-11-22 | 2024-03-20 | Basf Se | Pyrimidone derivatives containing two fused bicyclic rings |
US20230183245A1 (en) | 2020-04-06 | 2023-06-15 | Basf Se | Imidazo-pyrimidone compounds as pesticides |
CN115427408A (zh) | 2020-04-14 | 2022-12-02 | 巴斯夫欧洲公司 | 杀害虫的三环化合物 |
JP2024501464A (ja) | 2020-12-14 | 2024-01-12 | ビーエーエスエフ ソシエタス・ヨーロピア | スルホキシミン系殺虫剤 |
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WO2023041422A1 (en) | 2021-09-20 | 2023-03-23 | Basf Se | Heterocyclic compounds for the control of invertebrate pests |
WO2023088718A1 (en) | 2021-11-19 | 2023-05-25 | Basf Se | Bicyclic compounds for the control of invertebrate pests |
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- 2017-03-29 US US16/089,732 patent/US11570992B2/en active Active
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- 2017-03-29 CA CA3015934A patent/CA3015934A1/en active Pending
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- 2017-03-29 KR KR1020187030949A patent/KR102411744B1/ko active IP Right Grant
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BR112018068851A2 (pt) | 2019-01-22 |
US20190104738A1 (en) | 2019-04-11 |
KR102411744B1 (ko) | 2022-06-21 |
UA123912C2 (uk) | 2021-06-23 |
BR112018068851B1 (pt) | 2022-11-22 |
WO2017167832A1 (en) | 2017-10-05 |
KR20180132730A (ko) | 2018-12-12 |
EA038878B1 (ru) | 2021-11-01 |
US11570992B2 (en) | 2023-02-07 |
AU2017242539B2 (en) | 2020-10-15 |
MX2018012016A (es) | 2019-01-24 |
PE20181898A1 (es) | 2018-12-11 |
AU2017242539A1 (en) | 2018-09-27 |
EP3436457B1 (en) | 2022-07-20 |
PL3436457T3 (pl) | 2022-11-28 |
IL261551A (en) | 2018-10-31 |
IL261551B (en) | 2022-02-01 |
JP7027329B2 (ja) | 2022-03-01 |
CO2018010715A2 (es) | 2018-12-28 |
CL2018002794A1 (es) | 2018-11-16 |
EP3436457A1 (en) | 2019-02-06 |
CN108779121A (zh) | 2018-11-09 |
EA201892147A1 (ru) | 2019-04-30 |
AU2020281064A1 (en) | 2021-01-07 |
JP2019515890A (ja) | 2019-06-13 |
ES2928005T3 (es) | 2022-11-14 |
CA3015934A1 (en) | 2017-10-05 |
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