ZA976340B - Synthetic polysaccharides process for their preparation and pharmaceutical compositions containing them - Google Patents

Synthetic polysaccharides process for their preparation and pharmaceutical compositions containing them

Info

Publication number
ZA976340B
ZA976340B ZA976340A ZA976340A ZA976340B ZA 976340 B ZA976340 B ZA 976340B ZA 976340 A ZA976340 A ZA 976340A ZA 976340 A ZA976340 A ZA 976340A ZA 976340 B ZA976340 B ZA 976340B
Authority
ZA
South Africa
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
synthetic polysaccharides
polysaccharides
Prior art date
Application number
ZA976340A
Other languages
English (en)
Inventor
Pierre Alexandre Driguez
Philippe Duchaussoy
Jaen Marc Herbert
Maurice Petitou
Constant Van Boeckel
Peter Grootenhuis
Cornelia Dreef-Tromp
Johannes Basten
Original Assignee
Sanofi Sa
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa, Akzo Nobel Nv filed Critical Sanofi Sa
Publication of ZA976340B publication Critical patent/ZA976340B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA976340A 1996-07-19 1997-07-17 Synthetic polysaccharides process for their preparation and pharmaceutical compositions containing them ZA976340B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9609116A FR2751334B1 (fr) 1996-07-19 1996-07-19 Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Publications (1)

Publication Number Publication Date
ZA976340B true ZA976340B (en) 1999-01-22

Family

ID=9494266

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA976340A ZA976340B (en) 1996-07-19 1997-07-17 Synthetic polysaccharides process for their preparation and pharmaceutical compositions containing them

Country Status (36)

Country Link
US (1) US6534481B1 (zh)
EP (1) EP0912613B1 (zh)
JP (1) JP3345020B2 (zh)
KR (1) KR100311857B1 (zh)
CN (1) CN1200003C (zh)
AR (1) AR008068A1 (zh)
AT (1) ATE224917T1 (zh)
AU (1) AU726679B2 (zh)
BR (1) BR9710739B1 (zh)
CA (1) CA2261597C (zh)
CZ (1) CZ301009B6 (zh)
DE (1) DE69715866T2 (zh)
DK (1) DK0912613T3 (zh)
EE (1) EE03929B1 (zh)
ES (1) ES2184123T3 (zh)
FR (1) FR2751334B1 (zh)
HK (1) HK1019757A1 (zh)
HU (1) HU223691B1 (zh)
ID (1) ID20604A (zh)
IL (2) IL128018A0 (zh)
IS (1) IS1968B (zh)
MY (1) MY124548A (zh)
NO (1) NO319682B1 (zh)
NZ (1) NZ333721A (zh)
PL (1) PL190397B1 (zh)
PT (1) PT912613E (zh)
RU (1) RU2167163C2 (zh)
SA (1) SA99200037B1 (zh)
SI (1) SI0912613T1 (zh)
SK (1) SK284881B6 (zh)
TR (1) TR199900114T2 (zh)
TW (1) TW520376B (zh)
UA (1) UA61921C2 (zh)
WO (1) WO1998003554A1 (zh)
YU (1) YU49247B (zh)
ZA (1) ZA976340B (zh)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2773801B1 (fr) 1998-01-19 2000-05-12 Sanofi Sa Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
US7138531B2 (en) * 2001-10-15 2006-11-21 Kemin Pharma B.V.B.A. Preparation and use of carbohydrate-based bicyclic ring structures with antimicrobial and cytostatic activity
EP1574516A1 (en) * 2004-03-05 2005-09-14 Sanofi-Aventis Antithrombotic compound
US7563780B1 (en) * 2004-06-18 2009-07-21 Advanced Cardiovascular Systems, Inc. Heparin prodrugs and drug delivery stents formed therefrom
FR2874924B1 (fr) 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) * 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) * 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
IL181431A0 (en) * 2007-02-19 2007-07-04 Micha Shemer Fruit juice and puree with a lowered amount of available sugars
MX338213B (es) * 2007-10-16 2016-04-07 Progen Pharmaceuticals Ltd Derivados de oligosacaridos sulfatados novedosos.
KR101529061B1 (ko) 2008-05-30 2015-06-16 모멘타 파머슈티컬스 인코포레이티드 당류 구조물, 그리고 이러한 구조물의 제조 및 사용 방법
FR2935386B1 (fr) * 2008-08-26 2010-09-10 Sanofi Aventis Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine
CN104245718B (zh) 2009-07-31 2016-11-09 可靠生物医药公司 制备磺达肝素钠的方法及其合成中使用的中间体
FR2949115B1 (fr) 2009-08-14 2012-11-02 Sanofi Aventis OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2949114B1 (fr) 2009-08-14 2011-08-26 Sanofi Aventis OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
KR101682466B1 (ko) * 2010-02-01 2016-12-05 롯데정밀화학 주식회사 아세틸화 셀룰로오스 에테르 및 이를 포함하는 물품
JP2013537181A (ja) 2010-09-10 2013-09-30 サノフイ 抗血栓活性及び改善された代謝安定性を有するビオチン化多糖類
FR2970969B1 (fr) 2011-01-27 2013-10-18 Sanofi Aventis Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique
CN109134555B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途
CN109134553B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途
CN109134554B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801583A (en) 1982-01-15 1989-01-31 Choay S.A. Oligosaccharides and their biological applications
EP0300099A1 (en) 1987-07-20 1989-01-25 Akzo N.V. New pentasaccharides
US5378829A (en) 1990-04-23 1995-01-03 Akzo N.V. Sulfated glycosaminoglycanoid derivatives of the heparin and heparan sulfate type
US5382570A (en) 1990-04-23 1995-01-17 Akzo, N.V. Sulfated glycosaminoglycanoid derivatives of the dermatan sulfate and chondroitin sulfate type
IL102758A (en) 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
FR2704226B1 (fr) 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
DK0649854T3 (da) 1993-09-01 2000-07-03 Akzo Nobel Nv Biskonjugater omfattende to saccharider og en spacer
FR2749849B1 (fr) * 1996-06-14 1998-09-04 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
CN1228785A (zh) 1999-09-15
IL128018A0 (en) 1999-11-30
EP0912613A1 (fr) 1999-05-06
DE69715866D1 (de) 2002-10-31
UA61921C2 (uk) 2003-12-15
CN1200003C (zh) 2005-05-04
IL128018A (en) 2007-10-31
IS4945A (is) 1999-01-18
HUP9902287A1 (hu) 1999-10-28
RU2167163C2 (ru) 2001-05-20
MY124548A (en) 2006-06-30
ATE224917T1 (de) 2002-10-15
ES2184123T3 (es) 2003-04-01
SI0912613T1 (en) 2003-04-30
CZ16099A3 (cs) 1999-06-16
DE69715866T2 (de) 2003-05-28
EP0912613B1 (fr) 2002-09-25
CZ301009B6 (cs) 2009-10-14
AR008068A1 (es) 1999-12-09
IS1968B (is) 2004-12-15
FR2751334B1 (fr) 1998-10-16
BR9710739B1 (pt) 2008-11-18
TW520376B (en) 2003-02-11
CA2261597A1 (fr) 1998-01-29
AU726679B2 (en) 2000-11-16
YU49247B (sh) 2004-12-31
NZ333721A (en) 2000-08-25
TR199900114T2 (xx) 1999-03-22
CA2261597C (fr) 2004-12-14
PL190397B1 (pl) 2005-12-30
JP3345020B2 (ja) 2002-11-18
US6534481B1 (en) 2003-03-18
KR100311857B1 (ko) 2001-11-14
KR20000067909A (ko) 2000-11-25
EE03929B1 (et) 2002-12-16
EE9900015A (et) 1999-08-16
DK0912613T3 (da) 2003-01-27
NO990215L (no) 1999-03-18
NO990215D0 (no) 1999-01-18
PT912613E (pt) 2003-01-31
ID20604A (id) 1999-01-21
HUP9902287A3 (en) 2001-09-28
JP2000500807A (ja) 2000-01-25
AU3774797A (en) 1998-02-10
PL331259A1 (en) 1999-07-05
SK5399A3 (en) 2000-05-16
SK284881B6 (sk) 2006-02-02
NO319682B1 (no) 2005-09-05
YU1999A (sh) 2000-03-21
HK1019757A1 (en) 2000-02-25
FR2751334A1 (fr) 1998-01-23
WO1998003554A1 (fr) 1998-01-29
SA99200037B1 (ar) 2006-08-23
HU223691B1 (hu) 2004-12-28
BR9710739A (pt) 1999-08-17

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