ZA200807748B - Dihydropyrazolopyrimidinone derivatives - Google Patents

Dihydropyrazolopyrimidinone derivatives

Info

Publication number
ZA200807748B
ZA200807748B ZA200807748A ZA200807748A ZA200807748B ZA 200807748 B ZA200807748 B ZA 200807748B ZA 200807748 A ZA200807748 A ZA 200807748A ZA 200807748 A ZA200807748 A ZA 200807748A ZA 200807748 B ZA200807748 B ZA 200807748B
Authority
ZA
South Africa
Prior art keywords
dihydropyrazolopyrimidinone
derivatives
dihydropyrazolopyrimidinone derivatives
Prior art date
Application number
ZA200807748A
Other languages
English (en)
Inventor
Sakamoto Toshihiro
Yamamoto Fuyuki
Bamba Makoto
Furuyama Hidetomo
Otsuki Sachie
Yoshizumi Takashi
Sunami Satoshi
Niiyama Kenji
Takahashi Keiji
Sagara Takeshi
Nishibata Toshihide
Hirai Hiroshi
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38655640&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA200807748(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Publication of ZA200807748B publication Critical patent/ZA200807748B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200807748A 2006-04-27 2008-09-09 Dihydropyrazolopyrimidinone derivatives ZA200807748B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2006124208 2006-04-27

Publications (1)

Publication Number Publication Date
ZA200807748B true ZA200807748B (en) 2009-10-28

Family

ID=38655640

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200807748A ZA200807748B (en) 2006-04-27 2008-09-09 Dihydropyrazolopyrimidinone derivatives

Country Status (39)

Country Link
US (4) US7834019B2 (xx)
EP (2) EP2017278B1 (xx)
JP (2) JP4513919B2 (xx)
KR (1) KR101409161B1 (xx)
CN (1) CN101432284B (xx)
AR (1) AR060635A1 (xx)
AT (1) ATE475662T1 (xx)
AU (1) AU2007244185B2 (xx)
BR (1) BRPI0710081A2 (xx)
CA (1) CA2650119C (xx)
CR (1) CR10359A (xx)
CY (2) CY1111069T1 (xx)
DE (1) DE602007008085D1 (xx)
DK (2) DK2017278T3 (xx)
DO (1) DOP2007000084A (xx)
EC (1) ECSP088812A (xx)
ES (2) ES2609087T3 (xx)
GT (1) GT200800211A (xx)
HK (1) HK1132498A1 (xx)
HN (1) HN2008001532A (xx)
HR (2) HRP20100563T1 (xx)
HU (1) HUE032987T2 (xx)
IL (1) IL194367A (xx)
LT (1) LT2017278T (xx)
MA (1) MA30428B1 (xx)
MX (1) MX2008013063A (xx)
MY (1) MY145408A (xx)
NO (1) NO341617B1 (xx)
NZ (1) NZ571196A (xx)
PE (1) PE20080695A1 (xx)
PL (2) PL2017278T3 (xx)
PT (2) PT2017278T (xx)
RU (1) RU2437885C2 (xx)
SI (2) SI2016080T1 (xx)
SV (1) SV2009003060A (xx)
TW (1) TWI409262B (xx)
UA (1) UA96152C2 (xx)
WO (2) WO2007126128A1 (xx)
ZA (1) ZA200807748B (xx)

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JP6692423B2 (ja) * 2015-11-01 2020-05-13 ザ リージェンツ オブ ザ ユニヴァーシティ オブ コロラド，ア ボディ コーポレイト Ｗｅｅ１キナーゼ阻害剤、並びにそれを作製及び使用する方法
CN106271589B (zh) * 2016-06-23 2018-12-28 中山市美捷时包装制品有限公司 一种用于预装阀杆、弹簧、垫片的组装设备
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CN116848117A (zh) * 2021-02-09 2023-10-03 微境生物医药科技(上海)有限公司 作为Wee-1抑制剂的稠环化合物
JP2024515828A (ja) 2021-04-29 2024-04-10 ノバルティス アーゲー デユビキチナーゼ標的化キメラ及び関連する方法
CN117222648A (zh) 2021-04-30 2023-12-12 微境生物医药科技(上海)有限公司 作为Wee-1抑制剂的稠环化合物及其制备方法和用途
WO2022247641A1 (zh) 2021-05-28 2022-12-01 江苏天士力帝益药业有限公司 Wee1抑制剂及其用途
CN115838375A (zh) * 2021-09-18 2023-03-24 优领医药科技(香港)有限公司 含嘧啶并二氢吡唑啉酮类衍生物、其药学上可接受的盐及其制备方法和应用
CN113735863A (zh) * 2021-09-29 2021-12-03 武汉九州钰民医药科技有限公司 Wee1抑制剂adavosertib的制备工艺
CN113880844B (zh) * 2021-09-29 2023-02-14 武汉九州钰民医药科技有限公司 Wee1蛋白激酶抑制剂adavosertib的化学合成方法
WO2023072301A1 (zh) * 2021-11-01 2023-05-04 正大天晴药业集团股份有限公司 吡唑[3,4-d]嘧啶-3-酮类化合物及其医药用途
CN116462687A (zh) * 2022-01-18 2023-07-21 江苏天士力帝益药业有限公司 Wee1抑制剂及其制备和用途
CN116836184A (zh) * 2022-03-25 2023-10-03 药雅科技(上海)有限公司 Wee1激酶抑制剂的制备及其应用
CN115073460B (zh) * 2022-07-13 2023-07-25 苏州施安鼎泰生物医药技术有限公司 一种嘧啶并[5,4-c][2,6]萘啶衍生物及其制备方法以及药物组合物和应用
WO2024012549A1 (zh) * 2022-07-15 2024-01-18 映恩生物制药（苏州）有限公司 一种嘧啶并五元杂环化合物、其制备方法和用途

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