ZA200704451B - Multiple promoters and the use thereof for gene expression - Google Patents
Multiple promoters and the use thereof for gene expressionInfo
- Publication number
- ZA200704451B ZA200704451B ZA200704451A ZA200704451A ZA200704451B ZA 200704451 B ZA200704451 B ZA 200704451B ZA 200704451 A ZA200704451 A ZA 200704451A ZA 200704451 A ZA200704451 A ZA 200704451A ZA 200704451 B ZA200704451 B ZA 200704451B
- Authority
- ZA
- South Africa
- Prior art keywords
- gmo
- vector
- nucleic acid
- sequence
- new
- Prior art date
Links
- 230000014509 gene expression Effects 0.000 title abstract 4
- 108091026890 Coding region Proteins 0.000 abstract 1
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 abstract 1
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 abstract 1
- 230000001851 biosynthetic effect Effects 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/34—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Corynebacterium (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102004061846A DE102004061846A1 (de) | 2004-12-22 | 2004-12-22 | Mehrfachpromotoren |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200704451B true ZA200704451B (en) | 2009-05-27 |
Family
ID=36052084
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200704451A ZA200704451B (en) | 2004-12-22 | 2007-05-30 | Multiple promoters and the use thereof for gene expression |
Country Status (17)
Country | Link |
---|---|
US (1) | US7968699B2 (xx) |
EP (2) | EP1831374A1 (xx) |
JP (2) | JP2008523834A (xx) |
KR (1) | KR101155461B1 (xx) |
CN (2) | CN101230345B (xx) |
AT (1) | ATE542906T1 (xx) |
AU (1) | AU2005321577A1 (xx) |
BR (2) | BRPI0520842A2 (xx) |
CA (1) | CA2591311A1 (xx) |
DE (1) | DE102004061846A1 (xx) |
DK (1) | DK1908841T3 (xx) |
ES (1) | ES2380000T3 (xx) |
MX (1) | MX2007007392A (xx) |
PL (1) | PL1908841T3 (xx) |
RU (1) | RU2007127792A (xx) |
WO (1) | WO2006069711A1 (xx) |
ZA (1) | ZA200704451B (xx) |
Families Citing this family (36)
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JP5584470B2 (ja) * | 2007-01-12 | 2014-09-03 | アクトジェニックス・エヌブイ | ラクトコッカスプロモーター及びその使用 |
WO2008101857A2 (en) * | 2007-02-19 | 2008-08-28 | Evonik Degussa Gmbh | Coryneform bacteria with formate-thf-synthetase and/or glycine cleavage activity |
EP2121735A1 (en) * | 2007-02-19 | 2009-11-25 | Evonik Degussa GmbH | Method of producing methionine in corynebacteria by over-expressing enzymes of the pentose phosphate pathway |
GB0715416D0 (en) * | 2007-08-07 | 2007-09-19 | Phico Therapeutics Ltd | Modified bacteriophage |
EP2235194B1 (de) | 2008-01-23 | 2011-07-20 | Basf Se | Verfahren zur fermentativen Herstellung von 1,5-Diaminopentan |
US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
DE102009030342A1 (de) | 2009-06-25 | 2010-12-30 | Evonik Degussa Gmbh | Verfahren zur fermentativen Herstellung von organisch chemischen Verbindungen |
CN102753682A (zh) | 2009-12-17 | 2012-10-24 | 巴斯夫欧洲公司 | 用于生产尸胺的方法和重组微生物 |
DE102010003419B4 (de) | 2010-03-30 | 2019-09-12 | Evonik Degussa Gmbh | Verfahren zur fermentativen Herstellung von L-Ornithin |
WO2012114256A1 (en) | 2011-02-22 | 2012-08-30 | Basf Se | Processes and recombinant microorganisms for the production of cadaverine |
DE102011006716A1 (de) | 2011-04-04 | 2012-10-04 | Evonik Degussa Gmbh | Mikroorganismus und Verfahren zur fermentativen Herstellung einer organisch-chemischen Verbindung |
DE102011118019A1 (de) | 2011-06-28 | 2013-01-03 | Evonik Degussa Gmbh | Varianten des Promotors des für die Glyzerinaldehyd-3-phosphat-Dehydrogenase kodierenden gap-Gens |
PL2841568T3 (pl) | 2012-04-27 | 2018-07-31 | Evonik Technochemie Gmbh | Odporne na sprzężenie zwrotne syntazy alfa-izopropylojabłczanowe |
US20150353940A1 (en) * | 2013-08-05 | 2015-12-10 | Absci, Llc | Vectors for use in an inducible coexpression system |
EP2762571A1 (de) | 2013-01-30 | 2014-08-06 | Evonik Industries AG | Mikroorganismus und Verfahren zur fermentativen Herstellung von Aminosäuren |
PL2811028T3 (pl) | 2013-06-03 | 2017-07-31 | Evonik Degussa Gmbh | Sposób wytwarzania L-waliny z zastosowaniem zrekombinowanych bakterii maczugowatych zawierających operon ilvBN indukowany propionianem |
WO2014205518A1 (en) * | 2013-06-26 | 2014-12-31 | Phylogica Limited | Method of monitoring cellular trafficking of peptides |
CN104845923B (zh) | 2014-02-14 | 2018-03-23 | 中国科学院微生物研究所 | 生产l‑组氨酸的方法及其专用重组菌 |
CN105779447B (zh) * | 2014-12-22 | 2018-09-14 | 中国科学院大连化学物理研究所 | 3-磷酸甘油醛脱氢酶启动子和终止子及其应用 |
CN105779445B (zh) * | 2014-12-22 | 2018-09-28 | 中国科学院大连化学物理研究所 | 果糖-1,6-二磷酸醛缩酶启动子和终止子及其应用 |
CN105779446B (zh) * | 2014-12-22 | 2018-09-14 | 中国科学院大连化学物理研究所 | 3-磷酸甘油酸激酶启动子和终止子及其应用 |
US9988624B2 (en) | 2015-12-07 | 2018-06-05 | Zymergen Inc. | Microbial strain improvement by a HTP genomic engineering platform |
US11208649B2 (en) | 2015-12-07 | 2021-12-28 | Zymergen Inc. | HTP genomic engineering platform |
CA3007635A1 (en) | 2015-12-07 | 2017-06-15 | Zymergen Inc. | Promoters from corynebacterium glutamicum |
EP3478833A4 (en) | 2016-06-30 | 2019-10-02 | Zymergen, Inc. | METHODS OF GENERATING A BACTERIAL HEMOGLOBIN LIBRARY AND USES THEREOF |
WO2018005793A1 (en) | 2016-06-30 | 2018-01-04 | Zymergen Inc. | Methods for generating a glucose permease library and uses thereof |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
ES2921017T3 (es) * | 2016-12-30 | 2022-08-16 | Natures Toolbox Inc | Sistema de expresión libre de células que tiene una nueva regeneración de energía basada en polifosfato inorgánico |
CN110869504A (zh) | 2017-06-07 | 2020-03-06 | 齐默尔根公司 | 来自谷氨酸棒状杆菌的启动子及其在调节辅助基因表达中的用途 |
CN109142578B (zh) * | 2018-09-12 | 2021-08-10 | 中国人民解放军军事科学院军事医学研究院 | 检测生物细胞中两种基因对目标代谢物调控关系的方法 |
JP7498598B2 (ja) * | 2020-05-29 | 2024-06-12 | 花王株式会社 | 新規プロモーター |
CN115322990A (zh) * | 2021-05-10 | 2022-11-11 | 中国科学院天津工业生物技术研究所 | 具有启动子活性的多核苷酸及其在生产目标化合物中的用途 |
KR102604399B1 (ko) | 2021-07-21 | 2023-11-21 | 성균관대학교산학협력단 | 코리네박테리움 글루타미쿰의 모듈화 클로닝용 벡터 및 이의 용도 |
KR102632294B1 (ko) | 2021-08-27 | 2024-02-01 | 성균관대학교산학협력단 | 코리네박테리움 글루타미쿰의 모듈화 클로닝을 위한 프로모터 라이브러리 및 터미네이터 라이브러리, 및 이의 용도 |
CN114717237B (zh) * | 2022-06-10 | 2022-08-19 | 北京中科伊品生物科技有限公司 | 一种ep6启动子与其相关生物材料及应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5835197A (ja) | 1981-08-26 | 1983-03-01 | Kyowa Hakko Kogyo Co Ltd | プラスミドpcg2 |
US4601893A (en) | 1984-02-08 | 1986-07-22 | Pfizer Inc. | Laminate device for controlled and prolonged release of substances to an ambient environment and method of use |
GB2165546B (en) | 1984-08-21 | 1989-05-17 | Asahi Chemical Ind | A plasmid containing a gene for tetracycline resistance and dna fragments derived therefrom |
DE4027453A1 (de) | 1990-08-30 | 1992-03-05 | Degussa | Neue plasmide aus corynebacterium glutamicum und davon abgeleitete plasmidvektoren |
DE4440118C1 (de) | 1994-11-11 | 1995-11-09 | Forschungszentrum Juelich Gmbh | Die Genexpression in coryneformen Bakterien regulierende DNA |
JPH10229891A (ja) | 1997-02-20 | 1998-09-02 | Mitsubishi Rayon Co Ltd | マロン酸誘導体の製造法 |
JP4623825B2 (ja) * | 1999-12-16 | 2011-02-02 | 協和発酵バイオ株式会社 | 新規ポリヌクレオチド |
DE10046870A1 (de) | 2000-09-20 | 2002-03-28 | Basf Ag | Verfahren zur Veränderung des Genoms von Corynebakterien |
US7141388B2 (en) * | 2000-11-15 | 2006-11-28 | Archer-Daniels-Midland Company | Nucleotide sequences for transcriptional regulation in corynebacterium glutamicum |
CN1140628C (zh) * | 2001-11-02 | 2004-03-03 | 武汉大学 | 人白细胞白介素-12重组昆虫病毒株及其制备方法 |
DE10154180A1 (de) * | 2001-11-05 | 2003-05-15 | Basf Ag | gene die für genetische Stabilitäts-, genexpressions-und Faltungsproteine codieren |
DE10359660A1 (de) | 2003-12-18 | 2005-07-28 | Basf Ag | Psod-Expressionseinheiten |
DE10359595A1 (de) * | 2003-12-18 | 2005-07-28 | Basf Ag | Pgro-Expressionseinheiten |
DE10359594A1 (de) | 2003-12-18 | 2005-07-28 | Basf Ag | PEF-TU-Expressionseinheiten |
DE102004035065A1 (de) | 2004-07-20 | 2006-02-16 | Basf Ag | P-ET-TS-Expressionseinheiten |
-
2004
- 2004-12-22 DE DE102004061846A patent/DE102004061846A1/de not_active Withdrawn
-
2005
- 2005-12-21 PL PL07123772T patent/PL1908841T3/pl unknown
- 2005-12-21 JP JP2007547344A patent/JP2008523834A/ja not_active Withdrawn
- 2005-12-21 MX MX2007007392A patent/MX2007007392A/es not_active Application Discontinuation
- 2005-12-21 RU RU2007127792/13A patent/RU2007127792A/ru not_active Application Discontinuation
- 2005-12-21 KR KR1020077016617A patent/KR101155461B1/ko active IP Right Grant
- 2005-12-21 AU AU2005321577A patent/AU2005321577A1/en not_active Abandoned
- 2005-12-21 WO PCT/EP2005/013809 patent/WO2006069711A1/de active Application Filing
- 2005-12-21 DK DK07123772.1T patent/DK1908841T3/da active
- 2005-12-21 ES ES07123772T patent/ES2380000T3/es active Active
- 2005-12-21 EP EP05850322A patent/EP1831374A1/de not_active Withdrawn
- 2005-12-21 CN CN200710301192XA patent/CN101230345B/zh not_active Expired - Fee Related
- 2005-12-21 BR BRPI0520842-4A patent/BRPI0520842A2/pt not_active Application Discontinuation
- 2005-12-21 AT AT07123772T patent/ATE542906T1/de active
- 2005-12-21 CA CA002591311A patent/CA2591311A1/en not_active Abandoned
- 2005-12-21 EP EP07123772A patent/EP1908841B1/de not_active Revoked
- 2005-12-21 BR BRPI0519165-3A patent/BRPI0519165A2/pt not_active IP Right Cessation
- 2005-12-21 CN CNA2005800444228A patent/CN101087883A/zh active Pending
-
2007
- 2007-05-30 ZA ZA200704451A patent/ZA200704451B/xx unknown
-
2008
- 2008-03-14 US US12/048,599 patent/US7968699B2/en not_active Expired - Fee Related
- 2008-04-02 JP JP2008095920A patent/JP4763017B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US7968699B2 (en) | 2011-06-28 |
BRPI0519165A2 (pt) | 2008-12-30 |
RU2007127792A (ru) | 2009-01-27 |
JP4763017B2 (ja) | 2011-08-31 |
BRPI0520842A2 (pt) | 2012-07-03 |
EP1908841A1 (de) | 2008-04-09 |
MX2007007392A (es) | 2007-07-16 |
CA2591311A1 (en) | 2006-07-06 |
KR101155461B1 (ko) | 2012-09-07 |
JP2008212157A (ja) | 2008-09-18 |
DE102004061846A1 (de) | 2006-07-13 |
CN101230345A (zh) | 2008-07-30 |
PL1908841T3 (pl) | 2012-07-31 |
WO2006069711A1 (de) | 2006-07-06 |
AU2005321577A1 (en) | 2006-07-06 |
KR20070092745A (ko) | 2007-09-13 |
EP1831374A1 (de) | 2007-09-12 |
CN101230345B (zh) | 2013-03-20 |
ES2380000T3 (es) | 2012-05-07 |
CN101087883A (zh) | 2007-12-12 |
US20080268502A1 (en) | 2008-10-30 |
DK1908841T3 (da) | 2012-05-14 |
EP1908841B1 (de) | 2012-01-25 |
ATE542906T1 (de) | 2012-02-15 |
JP2008523834A (ja) | 2008-07-10 |
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