ZA200606070B - Substituted quinolines and their use as mycrobacterial inhibitors - Google Patents

Substituted quinolines and their use as mycrobacterial inhibitors

Info

Publication number
ZA200606070B
ZA200606070B ZA200606070A ZA200606070A ZA200606070B ZA 200606070 B ZA200606070 B ZA 200606070B ZA 200606070 A ZA200606070 A ZA 200606070A ZA 200606070 A ZA200606070 A ZA 200606070A ZA 200606070 B ZA200606070 B ZA 200606070B
Authority
ZA
South Africa
Prior art keywords
mycrobacterial
inhibitors
substituted quinolines
quinolines
substituted
Prior art date
Application number
ZA200606070A
Other languages
English (en)
Inventor
Jerome Emile Georges Guillemont
Elisabeth Therese Jeanne Pasquier
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZA200606070B publication Critical patent/ZA200606070B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA200606070A 2004-01-23 2006-07-21 Substituted quinolines and their use as mycrobacterial inhibitors ZA200606070B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53876804P 2004-01-23 2004-01-23

Publications (1)

Publication Number Publication Date
ZA200606070B true ZA200606070B (en) 2007-12-27

Family

ID=34807224

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200606070A ZA200606070B (en) 2004-01-23 2006-07-21 Substituted quinolines and their use as mycrobacterial inhibitors

Country Status (20)

Country Link
US (1) US7338949B2 (ko)
EP (1) EP1711492B1 (ko)
JP (1) JP4773975B2 (ko)
KR (1) KR101150172B1 (ko)
CN (1) CN1910177B (ko)
AP (1) AP2188A (ko)
AT (1) ATE392423T1 (ko)
AU (1) AU2005206330B2 (ko)
BR (1) BRPI0507076B8 (ko)
CA (1) CA2553266C (ko)
DE (1) DE602005006101T2 (ko)
EA (1) EA011359B1 (ko)
ES (1) ES2306082T3 (ko)
HK (1) HK1100927A1 (ko)
IL (1) IL177013A0 (ko)
NO (1) NO337705B1 (ko)
NZ (1) NZ547277A (ko)
UA (1) UA85570C2 (ko)
WO (1) WO2005070924A1 (ko)
ZA (1) ZA200606070B (ko)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005210036B2 (en) * 2004-01-29 2010-12-23 Janssen Pharmaceutica N.V. Quinoline derivatives for use as mycobacterial inhibitors
CA2528849C (en) 2005-06-08 2014-01-14 Janssen Pharmaceutica N.V. Quinoline derivatives as antibacterial agents
JO2855B1 (en) 2005-08-03 2015-03-15 شركة جانسين فارماسوتيكا ان. في Quinoline derivatives acting as antibacterial agents
JO2837B1 (en) * 2005-08-03 2014-09-15 جانسن فارمسيتكا ان في Quinoline derivatives acting as antibacterial agents
EP1917245A1 (de) 2005-08-21 2008-05-07 Abbott GmbH & Co. KG Heterocyclische verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren
JO2970B1 (en) 2006-12-06 2016-03-15 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2684B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
JO3271B1 (ar) 2006-12-06 2018-09-16 Janssen Pharmaceutica Nv مشتقات الكوينولين المضادة للجراثيم
JO2685B1 (en) 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
US20110059948A1 (en) * 2008-01-14 2011-03-10 Jyoti Chattopadhyaya Quinoline, naphthalene and conformationally constrained quinoline or naphthalene derivatives as anti-mycobacterial agents
EA038350B1 (ru) * 2012-04-27 2021-08-12 Янссен Фармацевтика Нв Антибактериальные хинолиновые производные
ES2576491T3 (es) * 2012-04-27 2016-07-07 Janssen Pharmaceutica, N.V. Derivados de quinolina antibacterianos
US10674732B2 (en) * 2015-04-29 2020-06-09 The State Of Israel, Ministry Of Agriculture & Rural Development Agricultural Research Organization Anti-phytopathogenic compositions

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2270123A1 (en) * 1996-10-28 1998-05-07 Department Of The Army, U.S. Government Compounds, compositions and methods for treating antibiotic-resistant infections
RU2209066C2 (ru) * 1997-06-02 2003-07-27 Янссен Фармацевтика Н.В. Производные (имидазол-5-ил)метил-2-хинолинона в качестве ингибиторов пролиферации клеток гладкой мышцы
US6103905A (en) * 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
HUP0003364A3 (en) * 1997-06-19 2002-03-28 Sepracor Inc Marlborough Quinoline-indole antimicrobial agents, uses and compositions related thereto
DE60130976T2 (de) * 2000-02-24 2008-07-17 Janssen Pharmaceutica N.V. Dosierschema enthaldend farnesyl protein transferase inhibitoren für die behandlung von krebs
BR0114253A (pt) * 2000-10-02 2003-07-01 Janssen Pharmaceutica Nv Antagonistas de receptor de glutamato metabotrópico
PL222801B1 (pl) * 2002-07-25 2016-09-30 Janssen Pharmaceutica Nv Pochodne chinoliny, ich zastosowanie, sposób ich wytwarzania oraz kompozycja farmaceutyczna zawierająca je

Also Published As

Publication number Publication date
BRPI0507076A (pt) 2007-06-19
AU2005206330B2 (en) 2010-09-16
KR20060127016A (ko) 2006-12-11
AU2005206330A1 (en) 2005-08-04
EA200601363A1 (ru) 2006-12-29
IL177013A0 (en) 2006-12-10
ATE392423T1 (de) 2008-05-15
WO2005070924A1 (en) 2005-08-04
WO2005070924A8 (en) 2006-05-11
NO20063747L (no) 2006-08-22
BRPI0507076B8 (pt) 2021-05-25
UA85570C2 (uk) 2009-02-10
AP2188A (en) 2010-12-14
CA2553266C (en) 2013-03-12
EP1711492A1 (en) 2006-10-18
ES2306082T3 (es) 2008-11-01
KR101150172B1 (ko) 2012-05-25
CA2553266A1 (en) 2005-08-04
US20070082895A1 (en) 2007-04-12
DE602005006101D1 (de) 2008-05-29
HK1100927A1 (en) 2007-10-05
NZ547277A (en) 2009-08-28
DE602005006101T2 (de) 2009-07-02
JP4773975B2 (ja) 2011-09-14
JP2007518775A (ja) 2007-07-12
US7338949B2 (en) 2008-03-04
CN1910177A (zh) 2007-02-07
BRPI0507076B1 (pt) 2019-06-25
CN1910177B (zh) 2010-05-05
NO337705B1 (no) 2016-06-06
AP2006003693A0 (en) 2006-08-31
EA011359B1 (ru) 2009-02-27
EP1711492B1 (en) 2008-04-16

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