AP2188A - Substituted quinolines and their use as mycobacterial inhibitors. - Google Patents

Substituted quinolines and their use as mycobacterial inhibitors.

Info

Publication number
AP2188A
AP2188A AP2006003693A AP2006003693A AP2188A AP 2188 A AP2188 A AP 2188A AP 2006003693 A AP2006003693 A AP 2006003693A AP 2006003693 A AP2006003693 A AP 2006003693A AP 2188 A AP2188 A AP 2188A
Authority
AP
ARIPO
Prior art keywords
substituted quinolines
mycobacterial inhibitors
mycobacterial
inhibitors
quinolines
Prior art date
Application number
AP2006003693A
Other languages
English (en)
Other versions
AP2006003693A0 (en
Inventor
Jerome Emile Georges Guillemont
Elisabeth Therese Jeanne Pasquier
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of AP2006003693A0 publication Critical patent/AP2006003693A0/xx
Application granted granted Critical
Publication of AP2188A publication Critical patent/AP2188A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AP2006003693A 2004-01-23 2005-01-21 Substituted quinolines and their use as mycobacterial inhibitors. AP2188A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53876804P 2004-01-23 2004-01-23
PCT/EP2005/050267 WO2005070924A1 (en) 2004-01-23 2005-01-21 Substituted quinolines and their use as mycobacterial inhibitors

Publications (2)

Publication Number Publication Date
AP2006003693A0 AP2006003693A0 (en) 2006-08-31
AP2188A true AP2188A (en) 2010-12-14

Family

ID=34807224

Family Applications (1)

Application Number Title Priority Date Filing Date
AP2006003693A AP2188A (en) 2004-01-23 2005-01-21 Substituted quinolines and their use as mycobacterial inhibitors.

Country Status (20)

Country Link
US (1) US7338949B2 (xx)
EP (1) EP1711492B1 (xx)
JP (1) JP4773975B2 (xx)
KR (1) KR101150172B1 (xx)
CN (1) CN1910177B (xx)
AP (1) AP2188A (xx)
AT (1) ATE392423T1 (xx)
AU (1) AU2005206330B2 (xx)
BR (1) BRPI0507076B8 (xx)
CA (1) CA2553266C (xx)
DE (1) DE602005006101T2 (xx)
EA (1) EA011359B1 (xx)
ES (1) ES2306082T3 (xx)
HK (1) HK1100927A1 (xx)
IL (1) IL177013A0 (xx)
NO (1) NO337705B1 (xx)
NZ (1) NZ547277A (xx)
UA (1) UA85570C2 (xx)
WO (1) WO2005070924A1 (xx)
ZA (1) ZA200606070B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005210036B2 (en) * 2004-01-29 2010-12-23 Janssen Pharmaceutica N.V. Quinoline derivatives for use as mycobacterial inhibitors
CA2528849C (en) 2005-06-08 2014-01-14 Janssen Pharmaceutica N.V. Quinoline derivatives as antibacterial agents
JO2855B1 (en) 2005-08-03 2015-03-15 شركة جانسين فارماسوتيكا ان. في Quinoline derivatives acting as antibacterial agents
JO2837B1 (en) * 2005-08-03 2014-09-15 جانسن فارمسيتكا ان في Quinoline derivatives acting as antibacterial agents
EP1917245A1 (de) 2005-08-21 2008-05-07 Abbott GmbH & Co. KG Heterocyclische verbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren
JO2970B1 (en) 2006-12-06 2016-03-15 جانسين فارماسوتيكا ان. في Quinoline antibacterial derivatives
JO2684B1 (en) * 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
JO3271B1 (ar) 2006-12-06 2018-09-16 Janssen Pharmaceutica Nv مشتقات الكوينولين المضادة للجراثيم
JO2685B1 (en) 2006-12-06 2013-03-03 جانسين فارماسوتيكا ان في Quinoline antibacterial derivatives
US20110059948A1 (en) * 2008-01-14 2011-03-10 Jyoti Chattopadhyaya Quinoline, naphthalene and conformationally constrained quinoline or naphthalene derivatives as anti-mycobacterial agents
EA038350B1 (ru) * 2012-04-27 2021-08-12 Янссен Фармацевтика Нв Антибактериальные хинолиновые производные
ES2576491T3 (es) * 2012-04-27 2016-07-07 Janssen Pharmaceutica, N.V. Derivados de quinolina antibacterianos
US10674732B2 (en) * 2015-04-29 2020-06-09 The State Of Israel, Ministry Of Agriculture & Rural Development Agricultural Research Organization Anti-phytopathogenic compositions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965572A (en) * 1996-10-28 1999-10-12 The United States Of America As Respresented By The Secretary Of The Army Methods for treating antibiotic-resistant infections
WO2000034265A2 (en) * 1998-12-11 2000-06-15 Sepracor, Inc. Quinoline-indole antimicrobial agents

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2209066C2 (ru) * 1997-06-02 2003-07-27 Янссен Фармацевтика Н.В. Производные (имидазол-5-ил)метил-2-хинолинона в качестве ингибиторов пролиферации клеток гладкой мышцы
HUP0003364A3 (en) * 1997-06-19 2002-03-28 Sepracor Inc Marlborough Quinoline-indole antimicrobial agents, uses and compositions related thereto
DE60130976T2 (de) * 2000-02-24 2008-07-17 Janssen Pharmaceutica N.V. Dosierschema enthaldend farnesyl protein transferase inhibitoren für die behandlung von krebs
BR0114253A (pt) * 2000-10-02 2003-07-01 Janssen Pharmaceutica Nv Antagonistas de receptor de glutamato metabotrópico
PL222801B1 (pl) * 2002-07-25 2016-09-30 Janssen Pharmaceutica Nv Pochodne chinoliny, ich zastosowanie, sposób ich wytwarzania oraz kompozycja farmaceutyczna zawierająca je

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5965572A (en) * 1996-10-28 1999-10-12 The United States Of America As Respresented By The Secretary Of The Army Methods for treating antibiotic-resistant infections
WO2000034265A2 (en) * 1998-12-11 2000-06-15 Sepracor, Inc. Quinoline-indole antimicrobial agents

Also Published As

Publication number Publication date
BRPI0507076A (pt) 2007-06-19
AU2005206330B2 (en) 2010-09-16
KR20060127016A (ko) 2006-12-11
AU2005206330A1 (en) 2005-08-04
EA200601363A1 (ru) 2006-12-29
IL177013A0 (en) 2006-12-10
ATE392423T1 (de) 2008-05-15
WO2005070924A1 (en) 2005-08-04
WO2005070924A8 (en) 2006-05-11
NO20063747L (no) 2006-08-22
BRPI0507076B8 (pt) 2021-05-25
UA85570C2 (uk) 2009-02-10
CA2553266C (en) 2013-03-12
EP1711492A1 (en) 2006-10-18
ES2306082T3 (es) 2008-11-01
KR101150172B1 (ko) 2012-05-25
CA2553266A1 (en) 2005-08-04
US20070082895A1 (en) 2007-04-12
DE602005006101D1 (de) 2008-05-29
HK1100927A1 (en) 2007-10-05
NZ547277A (en) 2009-08-28
DE602005006101T2 (de) 2009-07-02
ZA200606070B (en) 2007-12-27
JP4773975B2 (ja) 2011-09-14
JP2007518775A (ja) 2007-07-12
US7338949B2 (en) 2008-03-04
CN1910177A (zh) 2007-02-07
BRPI0507076B1 (pt) 2019-06-25
CN1910177B (zh) 2010-05-05
NO337705B1 (no) 2016-06-06
AP2006003693A0 (en) 2006-08-31
EA011359B1 (ru) 2009-02-27
EP1711492B1 (en) 2008-04-16

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