ZA200605226B - A crystalline form of the salt of 4-(3-chloro-4-(cyclo-propylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide or the solvate of the salt and a process for preparing the same - Google Patents
A crystalline form of the salt of 4-(3-chloro-4-(cyclo-propylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide or the solvate of the salt and a process for preparing the same Download PDFInfo
- Publication number
- ZA200605226B ZA200605226B ZA200605226A ZA200605226A ZA200605226B ZA 200605226 B ZA200605226 B ZA 200605226B ZA 200605226 A ZA200605226 A ZA 200605226A ZA 200605226 A ZA200605226 A ZA 200605226A ZA 200605226 B ZA200605226 B ZA 200605226B
- Authority
- ZA
- South Africa
- Prior art keywords
- crystalline form
- chloro
- methoxy
- aminophenoxy
- cyclopropylaminocarbonyl
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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| CN110563644A (zh) * | 2019-10-30 | 2019-12-13 | 北京赛思源生物医药技术有限公司 | 一种仑伐替尼甲磺酸盐的新晶型 |
| US11059787B2 (en) | 2019-11-12 | 2021-07-13 | Shenzhen Bolan Pharmaceutical Co., Ltd | Crystalline form of lenvatinib mesylate and methods thereof |
| CN111233762B (zh) * | 2020-02-20 | 2021-12-28 | 天津理工大学 | 一种乐伐替尼与对羟基苯甲酸共晶及其制备方法 |
| JP7466642B2 (ja) * | 2020-04-24 | 2024-04-12 | 成都苑東生物制薬股▲フン▼有限公司 | レンバチニブメシル酸塩結晶形ｘｉ及びその調製方法 |
| CN113999173A (zh) * | 2020-07-28 | 2022-02-01 | 药源药物化学（上海）有限公司 | 一种高纯度结晶的制备方法 |
| CN111793027B (zh) * | 2020-08-07 | 2021-12-03 | 天津理工大学 | 一种乐伐替尼与苯甲酸的共晶及其制备方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1339136C (fr) | 1987-07-01 | 1997-07-29 | Sailesh Amilal Varia | Forme amorphe de l'aztreonam |
| JP2517424Y2 (ja) | 1987-07-30 | 1996-11-20 | 株式会社 ナブコ | ポンプ装置 |
| JP2001131071A (ja) | 1999-10-29 | 2001-05-15 | Meiji Seika Kaisha Ltd | 非晶質および非晶質を含有する医薬組成物 |
| MX242553B (es) * | 2000-10-20 | 2006-12-06 | Eisai Co Ltd | Derivados aromaticos que contienen nitrogeno. |
| GB0119467D0 (en) | 2001-08-09 | 2001-10-03 | Smithkline Beecham Plc | Novel compound |
| JPWO2004039782A1 (ja) | 2002-10-29 | 2006-03-02 | 麒麟麦酒株式会社 | Ｆｌｔ３自己リン酸化を阻害するキノリン誘導体およびキナゾリン誘導体並びにそれらを含有する医薬組成物 |
| ATE508747T1 (de) * | 2003-03-10 | 2011-05-15 | Eisai R&D Man Co Ltd | C-kit kinase-hemmer |
| US20070117842A1 (en) * | 2003-04-22 | 2007-05-24 | Itaru Arimoto | Polymorph of 4-[3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy]-7-methoxy-6- quinolinecarboxamide and a process for the preparation of the same |
| JP4303726B2 (ja) | 2003-11-11 | 2009-07-29 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ウレア誘導体およびその製造方法 |
| CN101337933B (zh) | 2003-12-25 | 2011-03-02 | 卫材R&D管理有限公司 | 喹啉羧酰胺的甲磺酸盐的结晶(a)及其制备方法 |
| CN101001629B (zh) * | 2004-09-17 | 2010-05-05 | 卫材R&D管理有限公司 | 药物组合物 |
| US7550483B2 (en) * | 2005-06-23 | 2009-06-23 | Eisai R&D Management Co., Ltd. | Amorphous salt of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide and process for preparing the same |
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