MX2010008187A - Uso combinado de inhibidor de angiogenesis y taxano. - Google Patents
Uso combinado de inhibidor de angiogenesis y taxano.Info
- Publication number
- MX2010008187A MX2010008187A MX2010008187A MX2010008187A MX2010008187A MX 2010008187 A MX2010008187 A MX 2010008187A MX 2010008187 A MX2010008187 A MX 2010008187A MX 2010008187 A MX2010008187 A MX 2010008187A MX 2010008187 A MX2010008187 A MX 2010008187A
- Authority
- MX
- Mexico
- Prior art keywords
- taxane
- combined use
- angiogenesis inhibitor
- compound
- acceptable salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
El objeto es descubrir una composición farmacéutica que tiene un excelente efecto anti-tumoral y un método terapéutico para el cáncer. La 4-(3-cloro-4-(ciclopropilaminocarbonil)aminofenoxi)-7-m etoxi-6-quinolincarboxamida, un compuesto análogo o una de sus sales farmacológicamente aceptables o uno de sus solvatos pueden exhibir un excelente efecto anti-tumoral cuando se utiliza en combinación con texano.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2435908P | 2008-01-29 | 2008-01-29 | |
PCT/JP2009/051244 WO2009096377A1 (ja) | 2008-01-29 | 2009-01-27 | 血管阻害物質とタキサンとの併用 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010008187A true MX2010008187A (es) | 2010-08-10 |
Family
ID=40912730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010008187A MX2010008187A (es) | 2008-01-29 | 2009-01-27 | Uso combinado de inhibidor de angiogenesis y taxano. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20100324087A1 (es) |
EP (1) | EP2248804A4 (es) |
JP (1) | JP5399926B2 (es) |
KR (1) | KR101506062B1 (es) |
CN (1) | CN102036962B (es) |
AU (1) | AU2009210098B2 (es) |
BR (1) | BRPI0906576A2 (es) |
CA (1) | CA2713930A1 (es) |
IL (1) | IL207089A (es) |
MX (1) | MX2010008187A (es) |
WO (1) | WO2009096377A1 (es) |
Families Citing this family (23)
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US8969379B2 (en) | 2004-09-17 | 2015-03-03 | Eisai R&D Management Co., Ltd. | Pharmaceutical compositions of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7=methoxy-6-quinolinecarboxide |
US20100105031A1 (en) * | 2005-08-01 | 2010-04-29 | Esai R & D Management Co., Ltd. | Method for prediction of the efficacy of vascularization inhibitor |
WO2007015578A1 (ja) * | 2005-08-02 | 2007-02-08 | Eisai R & D Management Co., Ltd. | 血管新生阻害物質の効果を検定する方法 |
WO2007052849A1 (ja) | 2005-11-07 | 2007-05-10 | Eisai R & D Management Co., Ltd. | 血管新生阻害物質とc-kitキナーゼ阻害物質との併用 |
CA2652442C (en) | 2006-05-18 | 2014-12-09 | Eisai R & D Management Co., Ltd. | Antitumor agent for thyroid cancer |
KR101472600B1 (ko) | 2006-08-28 | 2014-12-15 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 미분화형 위암에 대한 항종양제 |
CA2676796C (en) | 2007-01-29 | 2016-02-23 | Eisai R & D Management Co., Ltd. | Composition for treatment of undifferentiated gastric cancer |
WO2009060945A1 (ja) | 2007-11-09 | 2009-05-14 | Eisai R & D Management Co., Ltd. | 血管新生阻害物質と抗腫瘍性白金錯体との併用 |
EP2586443B1 (en) * | 2010-06-25 | 2016-03-16 | Eisai R&D Management Co., Ltd. | Antitumor agent using compounds having kinase inhibitory effect in combination |
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CA2828946C (en) * | 2011-04-18 | 2016-06-21 | Eisai R&D Management Co., Ltd. | Therapeutic agent for tumor |
ES2705950T3 (es) | 2011-06-03 | 2019-03-27 | Eisai R&D Man Co Ltd | Biomarcadores para predecir y valorar la capacidad de respuesta de sujetos con cáncer de tiroides y de riñón a compuestos de lenvatinib |
TWI594986B (zh) | 2011-12-28 | 2017-08-11 | Taiho Pharmaceutical Co Ltd | Antineoplastic agent effect enhancer |
CN104755463A (zh) | 2012-12-21 | 2015-07-01 | 卫材R&D管理有限公司 | 非晶态形式的喹啉衍生物及其生产方法 |
MX368099B (es) | 2013-05-14 | 2019-09-19 | Eisai R&D Man Co Ltd | Biomarcadores para predecir y evaluar el grado de respuesta de sujetos con cancer de endometrio a compuestos de tipo lenvatinib. |
ES2705698T3 (es) | 2013-06-26 | 2019-03-26 | Eisai R&D Man Co Ltd | Terapia de combinación para el tratamiento del cáncer que comprende eribulina y lenvatinib |
JO3783B1 (ar) | 2014-08-28 | 2021-01-31 | Eisai R&D Man Co Ltd | مشتق كوينولين عالي النقاء وطريقة لإنتاجه |
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CN107801379B (zh) | 2015-06-16 | 2021-05-25 | 卫材R&D管理有限公司 | 抗癌剂 |
US20190000797A1 (en) * | 2015-08-20 | 2019-01-03 | Eisai R&D Management Co., Ltd. | Tumor therapeutic agent |
WO2017221214A1 (en) * | 2016-06-23 | 2017-12-28 | Sun Pharmaceutical Industries Limited | Crystalline forms of salts of lenvatinib |
WO2018151177A1 (ja) | 2017-02-15 | 2018-08-23 | 大鵬薬品工業株式会社 | 医薬組成物 |
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2009
- 2009-01-27 AU AU2009210098A patent/AU2009210098B2/en active Active
- 2009-01-27 MX MX2010008187A patent/MX2010008187A/es active IP Right Grant
- 2009-01-27 KR KR1020107018835A patent/KR101506062B1/ko active IP Right Grant
- 2009-01-27 CN CN2009801032187A patent/CN102036962B/zh active Active
- 2009-01-27 US US12/864,817 patent/US20100324087A1/en not_active Abandoned
- 2009-01-27 JP JP2009551518A patent/JP5399926B2/ja active Active
- 2009-01-27 CA CA2713930A patent/CA2713930A1/en not_active Abandoned
- 2009-01-27 EP EP09705712.9A patent/EP2248804A4/en not_active Withdrawn
- 2009-01-27 BR BRPI0906576-8A patent/BRPI0906576A2/pt not_active Application Discontinuation
- 2009-01-27 WO PCT/JP2009/051244 patent/WO2009096377A1/ja active Application Filing
-
2010
- 2010-07-19 IL IL207089A patent/IL207089A/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
CA2713930A1 (en) | 2009-08-06 |
WO2009096377A1 (ja) | 2009-08-06 |
AU2009210098A1 (en) | 2009-08-06 |
AU2009210098B2 (en) | 2013-06-13 |
KR101506062B1 (ko) | 2015-03-25 |
CN102036962B (zh) | 2013-08-07 |
EP2248804A4 (en) | 2014-09-10 |
IL207089A0 (en) | 2010-12-30 |
CN102036962A (zh) | 2011-04-27 |
US20100324087A1 (en) | 2010-12-23 |
JP5399926B2 (ja) | 2014-01-29 |
KR20100131439A (ko) | 2010-12-15 |
JPWO2009096377A1 (ja) | 2011-05-26 |
IL207089A (en) | 2015-02-26 |
EP2248804A1 (en) | 2010-11-10 |
BRPI0906576A2 (pt) | 2015-07-07 |
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