YU66900A - Derivati higromicina a - Google Patents

Derivati higromicina a

Info

Publication number
YU66900A
YU66900A YU66900A YU66900A YU66900A YU 66900 A YU66900 A YU 66900A YU 66900 A YU66900 A YU 66900A YU 66900 A YU66900 A YU 66900A YU 66900 A YU66900 A YU 66900A
Authority
YU
Yugoslavia
Prior art keywords
compounds
formula
infections
relates
hygromycin
Prior art date
Application number
YU66900A
Other languages
English (en)
Inventor
Katherine Elizabeth Brighty
Subramanian Sam Guhan
Martin Raymond Jefson
Ii Robert Gerald Linde
Ellen Lester Mccormick
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of YU66900A publication Critical patent/YU66900A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides

Abstract

Pronalazak se odnosi na jedinjenja formule 1 i na njihove farmaceutski prihvatljive soli, prekursore lekova i solvate, gde su R1 i R2 kao što je ovde definisano. Jedinjenja formule (1) pokazuju antibakterijska i antiprotozozolna dejstva. Pronalazak se odnosi na farmaceutske preparate koji sadrže jedinjenja formule (1) koji takodje imaju antibakterijske i antiprotozoalne osobine.[The invention relates to compounds of formula (1) and to pharmaceutically acceptable salts, prodrugs and solvates thereof, wherein R1 and R2 are as defined herein. The compounds of formula (1) are antibacterial and antiprotozoal agents that may be used to treat various bacterial and protozoal infections and disorders related to such infections. The invention also relates to pharmaceutical compositions containing the compounds of formula (1) and the methods of treating bacterial and protozoal infections by administering the compounds of formula (1).
YU66900A 1998-05-04 1999-05-03 Derivati higromicina a YU66900A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8404298P 1998-05-04 1998-05-04

Publications (1)

Publication Number Publication Date
YU66900A true YU66900A (sh) 2003-12-31

Family

ID=22182520

Family Applications (1)

Application Number Title Priority Date Filing Date
YU66900A YU66900A (sh) 1998-05-04 1999-05-03 Derivati higromicina a

Country Status (37)

Country Link
US (1) US6313100B1 (sh)
EP (1) EP1075483B1 (sh)
JP (1) JP2002513796A (sh)
KR (1) KR100402560B1 (sh)
CN (1) CN1299365A (sh)
AP (3) AP0102296A0 (sh)
AR (1) AR016251A1 (sh)
AT (2) ATE255588T1 (sh)
AU (1) AU755806B2 (sh)
BG (1) BG105008A (sh)
BR (1) BR9910206A (sh)
CA (1) CA2331297C (sh)
DE (2) DE69929723D1 (sh)
DK (1) DK1075483T3 (sh)
DZ (1) DZ2780A1 (sh)
EA (2) EA200200779A1 (sh)
ES (1) ES2209419T3 (sh)
GT (1) GT199900064A (sh)
HR (1) HRP20000747A2 (sh)
HU (1) HUP0102066A3 (sh)
ID (1) ID27030A (sh)
IL (1) IL139165A0 (sh)
IS (1) IS5681A (sh)
MA (1) MA24852A1 (sh)
NO (1) NO20005552L (sh)
NZ (1) NZ507452A (sh)
OA (1) OA11508A (sh)
PA (1) PA8471801A1 (sh)
PE (1) PE20000478A1 (sh)
PL (1) PL344521A1 (sh)
PT (1) PT1075483E (sh)
SK (1) SK16452000A3 (sh)
TN (1) TNSN99083A1 (sh)
TR (1) TR200003250T2 (sh)
WO (1) WO1999057125A2 (sh)
YU (1) YU66900A (sh)
ZA (1) ZA993064B (sh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK7302001A3 (en) * 1998-12-02 2001-12-03 Pfizer Prod Inc Hygromycin a derivatives as antibacterial agents
GB9923078D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
US6771019B1 (en) * 1999-05-14 2004-08-03 Ifire Technology, Inc. Electroluminescent laminate with patterned phosphor structure and thick film dielectric with improved dielectric properties
PL359179A1 (en) 2000-06-02 2004-08-23 Pfizer Products Inc. Hygromycin a derivatives for the treatment of bacterial and protozoal infections
CN102168034B (zh) * 2010-11-29 2012-12-05 中国科学院南海海洋研究所 一种海洋链霉菌以及利用该菌制备替达霉素a和b的方法
JP2016069333A (ja) * 2014-09-30 2016-05-09 公益財団法人微生物化学研究会 新規化合物、その製造方法、及びその用途、並びに、新規微生物
CN104480039B (zh) * 2014-11-25 2017-09-12 辽宁大学 抗生素产生菌及其应用
US20210275559A1 (en) * 2018-08-20 2021-09-09 Kim Lewis Hygromycin a compounds and methods of treating spirochete diseases
TWI771766B (zh) 2019-10-04 2022-07-21 美商輝瑞股份有限公司 二醯基甘油醯基轉移酶２ 抑制劑
JP2022058085A (ja) 2020-02-24 2022-04-11 ファイザー・インク ジアシルグリセロールアシルトランスフェラーゼ２阻害剤とアセチル－ＣｏＡカルボキシラーゼ阻害剤との組合せ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3674513D1 (de) * 1985-06-27 1990-10-31 Takeda Chemical Industries Ltd Verwendung von hygromycin und epihygromycin zur behandlung von dysentrie bei schweinen.
GB8605245D0 (en) * 1986-03-04 1986-04-09 Fujisawa Pharmaceutical Co Prophylactic & therapeutic agent

Also Published As

Publication number Publication date
US6313100B1 (en) 2001-11-06
AU3341999A (en) 1999-11-23
IS5681A (is) 2000-10-24
SK16452000A3 (sk) 2001-09-11
MA24852A1 (fr) 1999-12-31
WO1999057125A2 (en) 1999-11-11
EP1075483B1 (en) 2003-12-03
DE69929723D1 (de) 2006-04-20
NO20005552L (no) 2001-01-02
PE20000478A1 (es) 2000-05-31
AP9901527A0 (en) 1999-06-30
AU755806B2 (en) 2002-12-19
NZ507452A (en) 2003-04-29
AP1266A (en) 2004-03-29
AP2001002296A0 (en) 2001-12-31
CA2331297C (en) 2004-12-28
AP0102296A0 (en) 2000-11-04
PL344521A1 (en) 2001-11-05
DZ2780A1 (fr) 2005-04-23
EP1075483A2 (en) 2001-02-14
ATE317448T1 (de) 2006-02-15
HUP0102066A2 (hu) 2001-11-28
KR100402560B1 (ko) 2003-10-17
AR016251A1 (es) 2001-06-20
ES2209419T3 (es) 2004-06-16
EA200001029A1 (ru) 2001-04-23
CN1299365A (zh) 2001-06-13
EA200200779A1 (ru) 2002-12-26
KR20010043303A (ko) 2001-05-25
CA2331297A1 (en) 1999-11-11
OA11508A (en) 2004-02-09
EA003305B1 (ru) 2003-04-24
HUP0102066A3 (en) 2003-07-28
PT1075483E (pt) 2004-03-31
ZA993064B (en) 2000-12-06
NO20005552D0 (no) 2000-11-03
PA8471801A1 (es) 2000-09-29
ATE255588T1 (de) 2003-12-15
ID27030A (id) 2001-02-22
HRP20000747A2 (en) 2001-06-30
DE69913333D1 (de) 2004-01-15
BG105008A (en) 2001-09-28
DE69913333T2 (de) 2004-10-07
IL139165A0 (en) 2001-11-25
JP2002513796A (ja) 2002-05-14
TR200003250T2 (tr) 2001-01-22
TNSN99083A1 (fr) 2005-11-10
WO1999057125A3 (en) 1999-12-29
DK1075483T3 (da) 2004-03-15
BR9910206A (pt) 2001-01-30
GT199900064A (es) 2000-10-24

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