PA8471801A1 - Derivados de higromicina a - Google Patents

Derivados de higromicina a

Info

Publication number
PA8471801A1
PA8471801A1 PA19998471801A PA8471801A PA8471801A1 PA 8471801 A1 PA8471801 A1 PA 8471801A1 PA 19998471801 A PA19998471801 A PA 19998471801A PA 8471801 A PA8471801 A PA 8471801A PA 8471801 A1 PA8471801 A1 PA 8471801A1
Authority
PA
Panama
Prior art keywords
compounds
formula
infections
protozous
hygromycin
Prior art date
Application number
PA19998471801A
Other languages
English (en)
Inventor
Katherine Elizabeth Brighty
Ii Robert Gerald Linde
Martin Raymond Jefson
Ellen Lester Mccormick
Subramanian Sam Guhan
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PA8471801A1 publication Critical patent/PA8471801A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides

Abstract

ESTA INVENCION SE REFIERE A COMPUESTOS DE FORMULA 1 Y A SALES, PROFARMACOS Y SOLVATOS FARMACEUTICAMENTE ACEPTABLES DE LOS MISMOS, EN LA QUE R1 Y R2 SON COMO SE HAN DEFINIDO EN LA PRESENTE. LOS COMPUESTOS DE FORMULA 1 SON AGENTES ANTIBACTERIANOS Y ANTIPROTOZOARIOS QUE SE PUEDEN UTILIZAR PARA TRATAR DIVERSAS INFECCIONES POR BACTERIAS Y POR PROTOZOOS Y LOS TRASTORNOS RELACIONADOS CON TALES INFECCIONES. LA INVENCION TAMBIEN SE REFIERE A COMPOSICIONES FARMACEUTICAS QUE CONTIENEN LOS COMPUESTOS DE FORMULA 1 Y LOS PROCEDIMIENTOS DE TRATAMIENTO DE INFECCIONES POR BACTERIAS Y POR PROTOZOOS MEDIANTE LA ADMINISTRACION DE COMPUESTOS DE FORMULA 1.
PA19998471801A 1998-05-04 1999-05-04 Derivados de higromicina a PA8471801A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8404298P 1998-05-04 1998-05-04

Publications (1)

Publication Number Publication Date
PA8471801A1 true PA8471801A1 (es) 2000-09-29

Family

ID=22182520

Family Applications (1)

Application Number Title Priority Date Filing Date
PA19998471801A PA8471801A1 (es) 1998-05-04 1999-05-04 Derivados de higromicina a

Country Status (37)

Country Link
US (1) US6313100B1 (es)
EP (1) EP1075483B1 (es)
JP (1) JP2002513796A (es)
KR (1) KR100402560B1 (es)
CN (1) CN1299365A (es)
AP (3) AP0102296A0 (es)
AR (1) AR016251A1 (es)
AT (2) ATE255588T1 (es)
AU (1) AU755806B2 (es)
BG (1) BG105008A (es)
BR (1) BR9910206A (es)
CA (1) CA2331297C (es)
DE (2) DE69929723D1 (es)
DK (1) DK1075483T3 (es)
DZ (1) DZ2780A1 (es)
EA (2) EA200200779A1 (es)
ES (1) ES2209419T3 (es)
GT (1) GT199900064A (es)
HR (1) HRP20000747A2 (es)
HU (1) HUP0102066A3 (es)
ID (1) ID27030A (es)
IL (1) IL139165A0 (es)
IS (1) IS5681A (es)
MA (1) MA24852A1 (es)
NO (1) NO20005552L (es)
NZ (1) NZ507452A (es)
OA (1) OA11508A (es)
PA (1) PA8471801A1 (es)
PE (1) PE20000478A1 (es)
PL (1) PL344521A1 (es)
PT (1) PT1075483E (es)
SK (1) SK16452000A3 (es)
TN (1) TNSN99083A1 (es)
TR (1) TR200003250T2 (es)
WO (1) WO1999057125A2 (es)
YU (1) YU66900A (es)
ZA (1) ZA993064B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK7302001A3 (en) * 1998-12-02 2001-12-03 Pfizer Prod Inc Hygromycin a derivatives as antibacterial agents
GB9923078D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
US6771019B1 (en) * 1999-05-14 2004-08-03 Ifire Technology, Inc. Electroluminescent laminate with patterned phosphor structure and thick film dielectric with improved dielectric properties
PL359179A1 (en) 2000-06-02 2004-08-23 Pfizer Products Inc. Hygromycin a derivatives for the treatment of bacterial and protozoal infections
CN102168034B (zh) * 2010-11-29 2012-12-05 中国科学院南海海洋研究所 一种海洋链霉菌以及利用该菌制备替达霉素a和b的方法
JP2016069333A (ja) * 2014-09-30 2016-05-09 公益財団法人微生物化学研究会 新規化合物、その製造方法、及びその用途、並びに、新規微生物
CN104480039B (zh) * 2014-11-25 2017-09-12 辽宁大学 抗生素产生菌及其应用
US20210275559A1 (en) * 2018-08-20 2021-09-09 Kim Lewis Hygromycin a compounds and methods of treating spirochete diseases
TWI771766B (zh) 2019-10-04 2022-07-21 美商輝瑞股份有限公司 二醯基甘油醯基轉移酶２ 抑制劑
JP2022058085A (ja) 2020-02-24 2022-04-11 ファイザー・インク ジアシルグリセロールアシルトランスフェラーゼ２阻害剤とアセチル－ＣｏＡカルボキシラーゼ阻害剤との組合せ

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3674513D1 (de) * 1985-06-27 1990-10-31 Takeda Chemical Industries Ltd Verwendung von hygromycin und epihygromycin zur behandlung von dysentrie bei schweinen.
GB8605245D0 (en) * 1986-03-04 1986-04-09 Fujisawa Pharmaceutical Co Prophylactic & therapeutic agent

Also Published As

Publication number Publication date
US6313100B1 (en) 2001-11-06
AU3341999A (en) 1999-11-23
IS5681A (is) 2000-10-24
SK16452000A3 (sk) 2001-09-11
MA24852A1 (fr) 1999-12-31
WO1999057125A2 (en) 1999-11-11
EP1075483B1 (en) 2003-12-03
DE69929723D1 (de) 2006-04-20
NO20005552L (no) 2001-01-02
PE20000478A1 (es) 2000-05-31
AP9901527A0 (en) 1999-06-30
AU755806B2 (en) 2002-12-19
YU66900A (sh) 2003-12-31
NZ507452A (en) 2003-04-29
AP1266A (en) 2004-03-29
AP2001002296A0 (en) 2001-12-31
CA2331297C (en) 2004-12-28
AP0102296A0 (en) 2000-11-04
PL344521A1 (en) 2001-11-05
DZ2780A1 (fr) 2005-04-23
EP1075483A2 (en) 2001-02-14
ATE317448T1 (de) 2006-02-15
HUP0102066A2 (hu) 2001-11-28
KR100402560B1 (ko) 2003-10-17
AR016251A1 (es) 2001-06-20
ES2209419T3 (es) 2004-06-16
EA200001029A1 (ru) 2001-04-23
CN1299365A (zh) 2001-06-13
EA200200779A1 (ru) 2002-12-26
KR20010043303A (ko) 2001-05-25
CA2331297A1 (en) 1999-11-11
OA11508A (en) 2004-02-09
EA003305B1 (ru) 2003-04-24
HUP0102066A3 (en) 2003-07-28
PT1075483E (pt) 2004-03-31
ZA993064B (en) 2000-12-06
NO20005552D0 (no) 2000-11-03
ATE255588T1 (de) 2003-12-15
ID27030A (id) 2001-02-22
HRP20000747A2 (en) 2001-06-30
DE69913333D1 (de) 2004-01-15
BG105008A (en) 2001-09-28
DE69913333T2 (de) 2004-10-07
IL139165A0 (en) 2001-11-25
JP2002513796A (ja) 2002-05-14
TR200003250T2 (tr) 2001-01-22
TNSN99083A1 (fr) 2005-11-10
WO1999057125A3 (en) 1999-12-29
DK1075483T3 (da) 2004-03-15
BR9910206A (pt) 2001-01-30
GT199900064A (es) 2000-10-24

Similar Documents

Publication Publication Date Title
PA8489501A1 (es) Antibioticos cetolidos
PA8472301A1 (es) Derivados de isotiazol utiles como agentes anticancerosos
PA8486001A1 (es) Composiciones de celecoxib
PA8487601A1 (es) Derivados biciclicos sustituidos utiles como agentes contra el cancer
PA8452201A1 (es) Derivados de 9-desoxo-9a-aza-9a -homoeritromicina a c-4"sustituidos.
PA8452001A1 (es) Derivados de macrolidos c-4" sustituidos
UY25780A1 (es) Nuevos antibióticos macrólidos
BRPI0008614B8 (pt) composto inibidor tricíclico de poli(adp-ribose) polimerase, e composição farmacêuticas contendo tal composto.
PA8485601A1 (es) Azalidas de 13 miembros y su uso como agentes antibioticos.
PA8451801A1 (es) Derivados de la 9-oxima eritromicina
BR0010938A (pt) Derivados da 13-metil eritromicina
PA8471801A1 (es) Derivados de higromicina a
DE60102171D1 (de) Ketolidantibiotika
BR0006301A (pt) Macrólidos antibacterianos e pró-cinéticos
PA8471901A1 (es) Derivados de 2"-desoxi higromicina
PT1167376E (pt) Antibioticos macrolidos
SV2002000474A (es) Derivados de higromicina a ref.pc11o32abcz/bb
PA8474401A1 (es) 3-ceto derivados triciclicos de 6-0-metileritromicina
PA8505801A1 (es) Derivados de higromicina
AR019784A1 (es) Derivados de higromicina
ECSP992943A (es) Derivados de higromicina a
AR021816A1 (es) Antibioticos de carbamato y carbazato cetolida.
PA8505601A1 (es) Profarmacos de higromicina a
SV2002000210A (es) Profarmacos de higromicina a ref. pc10548ajnm/bb
ES2164892T3 (es) Polimorfos del profarmaco 6-n-(l-ala-l-ala)-trovafloxacino.