YU59201A - Matrica koja se može direktno komprimovati, za kontrolisano oslobadjanje pojedinačnih dnevnih doza klaritromicina - Google Patents
Matrica koja se može direktno komprimovati, za kontrolisano oslobadjanje pojedinačnih dnevnih doza klaritromicinaInfo
- Publication number
- YU59201A YU59201A YU59201A YUP59201A YU59201A YU 59201 A YU59201 A YU 59201A YU 59201 A YU59201 A YU 59201A YU P59201 A YUP59201 A YU P59201A YU 59201 A YU59201 A YU 59201A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- clarithromycin
- controlled release
- daily doses
- single daily
- directly compressible
- Prior art date
Links
- AGOYDEPGAOXOCK-KCBOHYOISA-N clarithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)C(=O)[C@H](C)C[C@](C)([C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)OC)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 AGOYDEPGAOXOCK-KCBOHYOISA-N 0.000 title abstract 2
- 229960002626 clarithromycin Drugs 0.000 title abstract 2
- 238000013270 controlled release Methods 0.000 title abstract 2
- 239000011159 matrix material Substances 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 abstract 1
- 230000002730 additional effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Pronalazak se odnosi na poboljšanu farmaceutsku formulaciju za kontrolisano oslobadjanje klaritromicina ili njegovih derivata, što je omogućeno sa novom kombinovanom matricom, koja se sastoji od masne komponente i od hidrofilne komponente, kojoj takodje mogu biti dodati surfaktant i pH modulator, kada je poželjan dodatni uticaj na profil oslobadjanja aktivne materije.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI9900039A SI20150A (sl) | 1999-02-19 | 1999-02-19 | Direktno stisljivi matriks za nadzorovano sproščanje celodnevne doze klaritromicina |
Publications (2)
Publication Number | Publication Date |
---|---|
YU59201A true YU59201A (sh) | 2004-07-15 |
RS50298B RS50298B (sr) | 2009-09-08 |
Family
ID=20432410
Country Status (21)
Country | Link |
---|---|
EP (1) | EP1150686B1 (sh) |
AT (1) | ATE286736T1 (sh) |
AU (1) | AU776912B2 (sh) |
BG (1) | BG65324B1 (sh) |
CY (1) | CY1107454T1 (sh) |
CZ (1) | CZ302781B6 (sh) |
DE (1) | DE60017361T2 (sh) |
DK (1) | DK1150686T3 (sh) |
EE (1) | EE05422B1 (sh) |
ES (1) | ES2235834T3 (sh) |
HR (1) | HRP20010684B1 (sh) |
HU (1) | HUP0105481A3 (sh) |
PL (1) | PL196665B1 (sh) |
PT (1) | PT1150686E (sh) |
RS (1) | RS50298B (sh) |
RU (1) | RU2237480C2 (sh) |
SI (2) | SI20150A (sh) |
SK (1) | SK287525B6 (sh) |
TR (1) | TR200102396T2 (sh) |
UA (1) | UA74778C2 (sh) |
WO (1) | WO2000048607A1 (sh) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TR200000054A2 (tr) * | 2000-01-05 | 2001-08-21 | Sanovel İlaç San. Ve Ti̇c. Anoni̇m Şi̇rketi̇ | Klaritromisin içeren sürekli salım sağlayan tablet formülasyonları. |
US6544555B2 (en) | 2000-02-24 | 2003-04-08 | Advancis Pharmaceutical Corp. | Antibiotic product, use and formulation thereof |
IN192748B (sh) * | 2000-08-29 | 2004-05-15 | Ranbaxy Lab Ltd | |
US20020068078A1 (en) | 2000-10-13 | 2002-06-06 | Rudnic Edward M. | Antifungal product, use and formulation thereof |
US6673369B2 (en) | 2001-08-29 | 2004-01-06 | Ranbaxy Laboratories Limited | Controlled release formulation |
CA2405918A1 (en) * | 2001-10-01 | 2003-04-01 | Ind-Swift Limited | Controlled release macrolide pharmaceutical formulations |
SE0103369D0 (sv) * | 2001-10-09 | 2001-10-09 | Astrazeneca Ab | Pharmaceutical formulation |
CA2465405A1 (en) | 2001-11-02 | 2003-05-08 | Wockhardt Limited | Controlled release compositions for macrolide antimicrobial agents |
AU2003214506A1 (en) * | 2002-04-03 | 2003-10-13 | Ranbaxy Laboratories Limited | Clarithromycin formulations having improved bioavailability |
US20060083759A1 (en) * | 2002-07-17 | 2006-04-20 | Aleksander Resman | Stabilization of the profile of release of active substances from a formulation |
US20050232995A1 (en) | 2002-07-29 | 2005-10-20 | Yam Nyomi V | Methods and dosage forms for controlled delivery of paliperidone and risperidone |
AU2003256848A1 (en) * | 2002-07-29 | 2004-02-16 | Alza Corporation | Formulations and dosage forms for controlled delivery of topiramate |
CA2535398C (en) | 2003-08-12 | 2013-11-12 | Advancis Pharmaceuticals Corporation | Antibiotic product, use and formulation thereof |
WO2005023221A1 (en) * | 2003-09-05 | 2005-03-17 | Ranbaxy Laboratories Limited | Clarithromycin formulations having improved biovailability |
US7943585B2 (en) * | 2003-12-22 | 2011-05-17 | Sandoz, Inc. | Extended release antibiotic composition |
WO2005102289A1 (en) * | 2004-03-24 | 2005-11-03 | Lupin Limited | Clarithromycin extended release formulation |
EP2283824B1 (en) | 2009-07-30 | 2017-04-19 | Special Products Line S.p.A. | Compositions and formulations based on swellable matrices for sustained release of poorly soluble drugs such as clarithromycin |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4331803A (en) * | 1980-06-04 | 1982-05-25 | Taisho Pharmaceutical Co., Ltd. | Novel erythromycin compounds |
JPS60163823A (ja) * | 1984-02-03 | 1985-08-26 | Taisho Pharmaceut Co Ltd | 経口投与製剤 |
JPS60214796A (ja) * | 1984-04-06 | 1985-10-28 | Taisho Pharmaceut Co Ltd | 6−0−メチルエリスロマイシン類の製法 |
JPS63188621A (ja) * | 1987-01-30 | 1988-08-04 | Taisho Pharmaceut Co Ltd | 矯味経口製剤 |
US4808411A (en) * | 1987-06-05 | 1989-02-28 | Abbott Laboratories | Antibiotic-polymer compositions |
IL87219A0 (en) * | 1987-08-07 | 1988-12-30 | Abbott Lab | Erythromycin formulations for oral administration |
JP2553882B2 (ja) * | 1987-08-08 | 1996-11-13 | 富士写真光機株式会社 | 走査結像光学系 |
US5599556A (en) * | 1991-12-31 | 1997-02-04 | Abbott Laboratories | Prolamine coatings for taste masking |
CA2182282C (en) * | 1994-02-16 | 2006-04-18 | Jacqueline E. Briskin | Process for preparing fine particle pharmaceutical formulations |
-
1999
- 1999-02-19 SI SI9900039A patent/SI20150A/sl not_active IP Right Cessation
-
2000
- 2000-02-17 SK SK1197-2001A patent/SK287525B6/sk not_active IP Right Cessation
- 2000-02-17 EP EP00905514A patent/EP1150686B1/en not_active Expired - Lifetime
- 2000-02-17 UA UA2001096230A patent/UA74778C2/uk unknown
- 2000-02-17 SI SI200030647T patent/SI1150686T1/xx unknown
- 2000-02-17 PT PT00905514T patent/PT1150686E/pt unknown
- 2000-02-17 AT AT00905514T patent/ATE286736T1/de active
- 2000-02-17 WO PCT/SI2000/000002 patent/WO2000048607A1/en active IP Right Grant
- 2000-02-17 PL PL350419A patent/PL196665B1/pl unknown
- 2000-02-17 CZ CZ20012964A patent/CZ302781B6/cs not_active IP Right Cessation
- 2000-02-17 DK DK00905514T patent/DK1150686T3/da active
- 2000-02-17 RS YUP-592/01A patent/RS50298B/sr unknown
- 2000-02-17 TR TR2001/02396T patent/TR200102396T2/xx unknown
- 2000-02-17 RU RU2001125667A patent/RU2237480C2/ru not_active IP Right Cessation
- 2000-02-17 DE DE60017361T patent/DE60017361T2/de not_active Expired - Lifetime
- 2000-02-17 EE EEP200100433A patent/EE05422B1/xx not_active IP Right Cessation
- 2000-02-17 HU HU0105481A patent/HUP0105481A3/hu unknown
- 2000-02-17 AU AU27049/00A patent/AU776912B2/en not_active Ceased
- 2000-02-17 ES ES00905514T patent/ES2235834T3/es not_active Expired - Lifetime
-
2001
- 2001-09-18 HR HR20010684A patent/HRP20010684B1/xx not_active IP Right Cessation
- 2001-09-19 BG BG105914A patent/BG65324B1/bg unknown
-
2005
- 2005-03-10 CY CY20051100330T patent/CY1107454T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
HUP0105481A2 (hu) | 2002-05-29 |
RU2237480C2 (ru) | 2004-10-10 |
CZ20012964A3 (cs) | 2002-01-16 |
BG65324B1 (bg) | 2008-02-29 |
DE60017361D1 (de) | 2005-02-17 |
SK287525B6 (sk) | 2011-01-04 |
DK1150686T3 (da) | 2005-04-04 |
HUP0105481A3 (en) | 2003-04-28 |
PT1150686E (pt) | 2005-05-31 |
PL196665B1 (pl) | 2008-01-31 |
UA74778C2 (en) | 2006-02-15 |
CZ302781B6 (cs) | 2011-11-02 |
ES2235834T3 (es) | 2005-07-16 |
WO2000048607A1 (en) | 2000-08-24 |
EE200100433A (et) | 2002-12-16 |
EP1150686B1 (en) | 2005-01-12 |
HRP20010684A2 (en) | 2002-10-31 |
DE60017361T2 (de) | 2005-12-22 |
CY1107454T1 (el) | 2012-12-19 |
HRP20010684B1 (en) | 2011-01-31 |
SK11972001A3 (sk) | 2002-02-05 |
EE05422B1 (et) | 2011-06-15 |
SI1150686T1 (en) | 2005-06-30 |
ATE286736T1 (de) | 2005-01-15 |
PL350419A1 (en) | 2002-12-16 |
BG105914A (bg) | 2002-05-31 |
RS50298B (sr) | 2009-09-08 |
AU2704900A (en) | 2000-09-04 |
TR200102396T2 (tr) | 2002-01-21 |
AU776912B2 (en) | 2004-09-23 |
EP1150686A1 (en) | 2001-11-07 |
SI20150A (sl) | 2000-08-31 |
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