YU40452B - Process for the elimination of contaminating impurities from clavulinic acid - Google Patents

Process for the elimination of contaminating impurities from clavulinic acid

Info

Publication number
YU40452B
YU40452B YU290/76A YU29076A YU40452B YU 40452 B YU40452 B YU 40452B YU 290/76 A YU290/76 A YU 290/76A YU 29076 A YU29076 A YU 29076A YU 40452 B YU40452 B YU 40452B
Authority
YU
Yugoslavia
Prior art keywords
elimination
contaminating impurities
clavulinic acid
clavulinic
acid
Prior art date
Application number
YU290/76A
Other languages
English (en)
Other versions
YU29076A (en
Inventor
I D Fleming
D Noble
H M Noble
W Wall
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB540975A external-priority patent/GB1543563A/en
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Publication of YU29076A publication Critical patent/YU29076A/xx
Publication of YU40452B publication Critical patent/YU40452B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D503/00Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
YU290/76A 1975-02-07 1976-02-06 Process for the elimination of contaminating impurities from clavulinic acid YU40452B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB540975A GB1543563A (en) 1975-02-07 1975-02-07 Beta-lactam antibiotic in purified form
GB1107675 1975-03-17

Publications (2)

Publication Number Publication Date
YU29076A YU29076A (en) 1982-08-31
YU40452B true YU40452B (en) 1986-02-28

Family

ID=26239868

Family Applications (1)

Application Number Title Priority Date Filing Date
YU290/76A YU40452B (en) 1975-02-07 1976-02-06 Process for the elimination of contaminating impurities from clavulinic acid

Country Status (15)

Country Link
US (3) US4490294A (ja)
JP (2) JPS51101994A (ja)
AT (1) AT353409B (ja)
AU (1) AU509313B2 (ja)
CH (1) CH624956A5 (ja)
DE (1) DE2604697A1 (ja)
DK (1) DK141099B (ja)
ES (1) ES444948A1 (ja)
FI (1) FI63580C (ja)
FR (1) FR2368276A1 (ja)
IE (1) IE43790B1 (ja)
IT (2) IT1059403B (ja)
NL (1) NL7601227A (ja)
SE (1) SE421796B (ja)
YU (1) YU40452B (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ177159A (en) * 1974-04-20 1978-03-06 Beecham Group Ltd Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions
GB1542405A (en) * 1975-04-15 1979-03-21 Beecham Group Ltd Clavulanic acid derivatives
DE2862254D1 (en) * 1977-12-02 1983-06-16 Beecham Group Plc A process for the preparation of ether derivatives of clavulanic acid
DE3063683D1 (en) * 1979-08-24 1983-07-14 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
GB9702216D0 (en) * 1997-02-04 1997-03-26 Smithkline Beecham Plc Novel product
GB9702218D0 (en) * 1997-02-04 1997-03-26 Smithkline Beecham Plc Novel product
PT867515E (pt) * 1997-03-24 2000-05-31 Cipan Companhia Ind P De Antib Processo para isolar um sal de acido clavulanico e de um metal alcalino farmaceuticamente aceitavel
JPH11254368A (ja) * 1998-03-12 1999-09-21 Central Motor Co Ltd 部材保持装置
MXPA00012930A (es) * 1998-07-03 2002-05-08 Dsm Nv Proceso de fermentacion para producir acido clavulanico en una concentracion baja de aminoacidos libres.
PT102181A (pt) * 1998-07-20 2000-01-31 Dsm Nv Processo melhorado para a producao de acido clavulanico
IL155194A0 (en) * 2000-10-05 2003-11-23 Biogal Pharmaceutical Co Ltd Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same
US20040072815A1 (en) * 2002-02-12 2004-04-15 Koppel Gary A. Antibiotic composition and method
KR100461278B1 (ko) * 2002-10-23 2004-12-10 현대자동차주식회사 용접 대상물의 위치규제 및 취출장치
BR112020006001A2 (pt) 2017-10-02 2020-10-13 Metabolic Explorer método para produção de sais de ácido orgânico a partir de caldo de fermentação

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754693A (fr) * 1969-08-12 1971-02-11 Lilly Co Eli Nouvel antibiotique et procede pour le preparer
NZ177159A (en) * 1974-04-20 1978-03-06 Beecham Group Ltd Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions
JO984B1 (en) * 1977-10-11 1979-12-01 بيتشام غروب ليمتد A dry pharmaceutical compound with a suitable dosage unit for oral administration

Also Published As

Publication number Publication date
DE2604697C2 (ja) 1992-10-29
ES444948A1 (es) 1977-08-16
AT353409B (de) 1979-11-12
IT1066098B (it) 1985-03-04
IE43790B1 (en) 1981-06-03
DK141099B (da) 1980-01-14
US4367175A (en) 1983-01-04
ATA83476A (de) 1979-04-15
YU29076A (en) 1982-08-31
AU1089176A (en) 1977-08-11
NL7601227A (nl) 1976-08-10
FI63580B (fi) 1983-03-31
SE421796B (sv) 1982-02-01
DK141099C (ja) 1980-07-21
CH624956A5 (de) 1981-08-31
US4490295A (en) 1984-12-25
JPS51101994A (ja) 1976-09-08
IE43790L (en) 1976-08-07
AU509313B2 (en) 1980-05-08
FR2368276A1 (fr) 1978-05-19
US4490294A (en) 1984-12-25
FI760285A (ja) 1976-08-08
FR2368276B1 (ja) 1979-03-16
IT1059403B (it) 1982-05-31
SE7601337L (sv) 1976-11-03
DK49876A (ja) 1976-08-08
FI63580C (fi) 1983-07-11
JPH0222281A (ja) 1990-01-25
DE2604697A1 (de) 1976-08-19

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