SE421796B - Forfarande for rening av klavulansyra och dess salter - Google Patents

Forfarande for rening av klavulansyra och dess salter

Info

Publication number
SE421796B
SE421796B SE7601337A SE7601337A SE421796B SE 421796 B SE421796 B SE 421796B SE 7601337 A SE7601337 A SE 7601337A SE 7601337 A SE7601337 A SE 7601337A SE 421796 B SE421796 B SE 421796B
Authority
SE
Sweden
Prior art keywords
purification
salts
procedure
clavulanic acid
clavulanic
Prior art date
Application number
SE7601337A
Other languages
English (en)
Other versions
SE7601337L (sv
Inventor
I D Fleming
D Noble
H M Noble
W F Wall
Original Assignee
Glaxo Lab Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB540975A external-priority patent/GB1543563A/en
Application filed by Glaxo Lab Ltd filed Critical Glaxo Lab Ltd
Publication of SE7601337L publication Critical patent/SE7601337L/sv
Publication of SE421796B publication Critical patent/SE421796B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SE7601337A 1975-02-07 1976-02-06 Forfarande for rening av klavulansyra och dess salter SE421796B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB540975A GB1543563A (en) 1975-02-07 1975-02-07 Beta-lactam antibiotic in purified form
GB1107675 1975-03-17

Publications (2)

Publication Number Publication Date
SE7601337L SE7601337L (sv) 1976-11-03
SE421796B true SE421796B (sv) 1982-02-01

Family

ID=26239868

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7601337A SE421796B (sv) 1975-02-07 1976-02-06 Forfarande for rening av klavulansyra och dess salter

Country Status (15)

Country Link
US (3) US4490294A (sv)
JP (2) JPS51101994A (sv)
AT (1) AT353409B (sv)
AU (1) AU509313B2 (sv)
CH (1) CH624956A5 (sv)
DE (1) DE2604697A1 (sv)
DK (1) DK141099B (sv)
ES (1) ES444948A1 (sv)
FI (1) FI63580C (sv)
FR (1) FR2368276A1 (sv)
IE (1) IE43790B1 (sv)
IT (2) IT1059403B (sv)
NL (1) NL7601227A (sv)
SE (1) SE421796B (sv)
YU (1) YU40452B (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ177159A (en) * 1974-04-20 1978-03-06 Beecham Group Ltd Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions
GB1542405A (en) * 1975-04-15 1979-03-21 Beecham Group Ltd Clavulanic acid derivatives
DE2862254D1 (en) * 1977-12-02 1983-06-16 Beecham Group Plc A process for the preparation of ether derivatives of clavulanic acid
DE3063683D1 (en) * 1979-08-24 1983-07-14 Beecham Group Plc Amine salt of clavulanic acid, its preparation and use
GB9702216D0 (en) * 1997-02-04 1997-03-26 Smithkline Beecham Plc Novel product
GB9702218D0 (en) * 1997-02-04 1997-03-26 Smithkline Beecham Plc Novel product
PT867515E (pt) * 1997-03-24 2000-05-31 Cipan Companhia Ind P De Antib Processo para isolar um sal de acido clavulanico e de um metal alcalino farmaceuticamente aceitavel
JPH11254368A (ja) * 1998-03-12 1999-09-21 Central Motor Co Ltd 部材保持装置
MXPA00012930A (es) * 1998-07-03 2002-05-08 Dsm Nv Proceso de fermentacion para producir acido clavulanico en una concentracion baja de aminoacidos libres.
PT102181A (pt) * 1998-07-20 2000-01-31 Dsm Nv Processo melhorado para a producao de acido clavulanico
IL155194A0 (en) * 2000-10-05 2003-11-23 Biogal Pharmaceutical Co Ltd Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same
US20040072815A1 (en) * 2002-02-12 2004-04-15 Koppel Gary A. Antibiotic composition and method
KR100461278B1 (ko) * 2002-10-23 2004-12-10 현대자동차주식회사 용접 대상물의 위치규제 및 취출장치
BR112020006001A2 (pt) 2017-10-02 2020-10-13 Metabolic Explorer método para produção de sais de ácido orgânico a partir de caldo de fermentação

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754693A (fr) * 1969-08-12 1971-02-11 Lilly Co Eli Nouvel antibiotique et procede pour le preparer
NZ177159A (en) * 1974-04-20 1978-03-06 Beecham Group Ltd Clavulanic acid, salts, esters and preparation thereof from streptomyces clavuligerus: pharmaceutical compositions
JO984B1 (en) * 1977-10-11 1979-12-01 بيتشام غروب ليمتد A dry pharmaceutical compound with a suitable dosage unit for oral administration

Also Published As

Publication number Publication date
DE2604697C2 (sv) 1992-10-29
ES444948A1 (es) 1977-08-16
AT353409B (de) 1979-11-12
IT1066098B (it) 1985-03-04
IE43790B1 (en) 1981-06-03
DK141099B (da) 1980-01-14
US4367175A (en) 1983-01-04
ATA83476A (de) 1979-04-15
YU29076A (en) 1982-08-31
AU1089176A (en) 1977-08-11
NL7601227A (nl) 1976-08-10
FI63580B (fi) 1983-03-31
DK141099C (sv) 1980-07-21
CH624956A5 (de) 1981-08-31
US4490295A (en) 1984-12-25
YU40452B (en) 1986-02-28
JPS51101994A (sv) 1976-09-08
IE43790L (en) 1976-08-07
AU509313B2 (en) 1980-05-08
FR2368276A1 (fr) 1978-05-19
US4490294A (en) 1984-12-25
FI760285A (sv) 1976-08-08
FR2368276B1 (sv) 1979-03-16
IT1059403B (it) 1982-05-31
SE7601337L (sv) 1976-11-03
DK49876A (sv) 1976-08-08
FI63580C (fi) 1983-07-11
JPH0222281A (ja) 1990-01-25
DE2604697A1 (de) 1976-08-19

Similar Documents

Publication Publication Date Title
JPS5223016A (en) Method of purification acetic acid
SE7611604L (sv) Forfarande for rening av halogensilaner
US6031093C1 (en) Solid salts of clavulanic acid
SE421796B (sv) Forfarande for rening av klavulansyra och dess salter
SE7607875L (sv) Forfarande for framstellning av prostansyraderivat
NZ182120A (en) Production of clavulanic acid and its salts from streptomyces jumanjinensis
SE7514548L (sv) Forfarande for framstellning och rening av chenodioxicholsyra
SE7608767L (sv) Forfarande for framstellning av glasforemal
JPS5217413A (en) Method of purification acetic acid
SE405597B (sv) Sett for kontinuerlig framstellning av vattenfria losningar av perpropionsyra
SE440080B (sv) Forfarande for framstellning av klavulansyraderivat
SE7600369L (sv) Anordning for behandling av utsede
HU171662B (hu) Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh apovinkaminola i ikh kislotnykh adduktov
SE7804261L (sv) Forfarande for framstellning av prostansyraderivat
JPS5236624A (en) Method of manufacturing 55oxohfxanic acid and its derivatives
BG27365A3 (en) Method of obtaining of perpropionic acid solutions
SE431980B (sv) Forfarande for framstellning av tiokarbamidsyraestrar
SE7603801L (sv) Filter for behandling av vetskor
DK561776A (da) Thiadiazolylderivater af 7-acylamido-3-cephem-4-carboxylsyre og fremgangsmade til fremstilling deraf
SE7603768L (sv) Forfarande och anordning for framstellning av optiska formdelar
SE7610890L (sv) Forfarande for framstellning av cyanursyra
BG27364A3 (en) Method of obtaining of perpropionic acid solutions
SE423551B (sv) Forfaringssett och anleggning for behandling av sur tjera
SE442748B (sv) Forfarande for framstellning av etrar av klavulansyra
SE7601542L (sv) Forfarande for samtidig koncentrering och rening av fosforsyralosningar

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7601337-4

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 7601337-4

Format of ref document f/p: F