UY29709A1 - "compuestos quimicos" - Google Patents
"compuestos quimicos"Info
- Publication number
- UY29709A1 UY29709A1 UY29709A UY29709A UY29709A1 UY 29709 A1 UY29709 A1 UY 29709A1 UY 29709 A UY29709 A UY 29709A UY 29709 A UY29709 A UY 29709A UY 29709 A1 UY29709 A1 UY 29709A1
- Authority
- UY
- Uruguay
- Prior art keywords
- compounds
- chemical compounds
- pyrimidine
- activity
- ylcarbonyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Abstract
Se describen compuestos de fórmula (I): que poseen actividad inhibitoria del ciclo celular. Los compuestos son derivados de pirimidina e imidazol, utiles debido a su actividad antiproliferacion celular (anticancer), para el tratamiento del cuerpo humano y animal. Se citan 208 ejemplos de compuestos, siendo el primero: 5-fluoro-4-(1-isopropil-2-metil-1H-imidazol-5-il)-N-(4-(morfolin-4-ilcarbonil) fenil) pirimidin-2-amida.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0515743A GB0515743D0 (en) | 2005-07-30 | 2005-07-30 | Chemical compounds |
GB0520281A GB0520281D0 (en) | 2005-10-06 | 2005-10-06 | Chemical compounds |
GB0526015A GB0526015D0 (en) | 2005-12-22 | 2005-12-22 | Chemical compounds |
GB0608371A GB0608371D0 (en) | 2006-04-28 | 2006-04-28 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
UY29709A1 true UY29709A1 (es) | 2007-02-28 |
Family
ID=37339792
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY29709A UY29709A1 (es) | 2005-07-30 | 2006-07-28 | "compuestos quimicos" |
Country Status (14)
Country | Link |
---|---|
US (1) | US20080280906A1 (es) |
EP (2) | EP2301928A1 (es) |
JP (2) | JP4278172B2 (es) |
KR (1) | KR20080033450A (es) |
AR (1) | AR054879A1 (es) |
AU (1) | AU2006274733B2 (es) |
BR (1) | BRPI0614502A2 (es) |
CA (1) | CA2617170A1 (es) |
IL (1) | IL188390A0 (es) |
MX (1) | MX2008001428A (es) |
NO (1) | NO20080061L (es) |
TW (1) | TW200738686A (es) |
UY (1) | UY29709A1 (es) |
WO (1) | WO2007015064A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20080033450A (ko) * | 2005-07-30 | 2008-04-16 | 아스트라제네카 아베 | 증식성 질환의 치료에 사용하기 위한 이미다졸릴-피리미딘화합물 |
AR058073A1 (es) * | 2005-10-03 | 2008-01-23 | Astrazeneca Ab | Derivados de imidazol 5-il-pirimidina, procesos de obtencion, composiciones farmaceuticas y usos |
TW200811169A (en) * | 2006-05-26 | 2008-03-01 | Astrazeneca Ab | Chemical compounds |
AR076300A1 (es) | 2009-04-15 | 2011-06-01 | Astrazeneca Ab | Derivados de pirimidin imidazoles sustituidos, inhibidores de gsk3, composiciones farmaceuticas que los contienen y usos de los mismos en el tratamiento del alzheimer, enfermedades neurodegenerativas agudas, diabetes y otras enfermedades. |
CA2764387A1 (en) | 2009-06-05 | 2010-12-09 | Link Medicine Corporation | Aminopyrrolidinone derivatives and uses thereof |
WO2016016131A1 (en) | 2014-07-31 | 2016-02-04 | Syngenta Participations Ag | Pesticidally active cyclic enaminones |
US10774064B2 (en) | 2016-06-02 | 2020-09-15 | Cadent Therapeutics, Inc. | Potassium channel modulators |
EP3571193B1 (en) | 2017-01-23 | 2021-12-01 | Cadent Therapeutics, Inc. | Potassium channel modulators |
Family Cites Families (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4659363A (en) * | 1983-07-25 | 1987-04-21 | Ciba-Geigy Corporation | N-(2-nitrophenyl)-2-aminopyrimidine derivatives, the preparation and use thereof |
US4983608A (en) * | 1989-09-05 | 1991-01-08 | Hoechst-Roussell Pharmaceuticals, Inc. | N-substituted-4-pyrimidinamines and pyrimidinediamines |
US5521184A (en) * | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
JP2932693B2 (ja) * | 1992-10-05 | 1999-08-09 | 宇部興産株式会社 | ピリミジン化合物 |
US5516184A (en) * | 1994-04-21 | 1996-05-14 | Henninges Elastomer-Und Kunststofftechnik, Gmbh & Co. | Motor-vehicle window pivot |
US5739143A (en) * | 1995-06-07 | 1998-04-14 | Smithkline Beecham Corporation | Imidazole compounds and compositions |
ATE294174T1 (de) * | 1996-06-10 | 2005-05-15 | Merck & Co Inc | Substituierte imidazole mit cytokinin- inhibirender wirkung |
ES2267873T3 (es) | 1997-10-27 | 2007-03-16 | Agouron Pharmaceuticals, Inc. | Derivados de 4-aminotiazol, su preparacion y uso como inhibidores de kinasas dependientes de ciclina. |
US6432963B1 (en) * | 1997-12-15 | 2002-08-13 | Yamanouchi Pharmaceutical Co., Ltd. | Pyrimidine-5-carboxamide derivatives |
ATE245641T1 (de) * | 1998-02-17 | 2003-08-15 | Tularik Inc | Antivirale pyrimidinderivate |
AU5438499A (en) * | 1998-08-29 | 2000-03-21 | Astrazeneca Ab | Pyrimidine compounds |
DE69933680T2 (de) * | 1998-08-29 | 2007-08-23 | Astrazeneca Ab | Pyrimidine verbindungen |
GB9828511D0 (en) * | 1998-12-24 | 1999-02-17 | Zeneca Ltd | Chemical compounds |
GB9905075D0 (en) * | 1999-03-06 | 1999-04-28 | Zeneca Ltd | Chemical compounds |
GB9907658D0 (en) * | 1999-04-06 | 1999-05-26 | Zeneca Ltd | Chemical compounds |
GB9919778D0 (en) * | 1999-08-21 | 1999-10-27 | Zeneca Ltd | Chemical compounds |
US7101869B2 (en) * | 1999-11-30 | 2006-09-05 | Pfizer Inc. | 2,4-diaminopyrimidine compounds useful as immunosuppressants |
GB0004888D0 (en) * | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
GB0004887D0 (en) * | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
GB0004890D0 (en) * | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
GB0004886D0 (en) * | 2000-03-01 | 2000-04-19 | Astrazeneca Uk Ltd | Chemical compounds |
GB0007371D0 (en) * | 2000-03-28 | 2000-05-17 | Astrazeneca Uk Ltd | Chemical compounds |
GB0016877D0 (en) * | 2000-07-11 | 2000-08-30 | Astrazeneca Ab | Chemical compounds |
GB0021726D0 (en) * | 2000-09-05 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
GB0103926D0 (en) * | 2001-02-17 | 2001-04-04 | Astrazeneca Ab | Chemical compounds |
RS94703A (en) * | 2001-05-29 | 2007-02-05 | Schering Aktiengesellschaft, | Cdk inhibiting pyrimidines, production thereof and their use as medicaments |
GB0113041D0 (en) * | 2001-05-30 | 2001-07-18 | Astrazeneca Ab | Chemical compounds |
SE0102439D0 (sv) | 2001-07-05 | 2001-07-05 | Astrazeneca Ab | New compounds |
WO2003011837A1 (en) * | 2001-08-01 | 2003-02-13 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
CN1582284A (zh) * | 2001-11-07 | 2005-02-16 | 霍夫曼-拉罗奇有限公司 | 氨基嘧啶类和吡啶类化合物 |
GB0205693D0 (en) | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
GB0205690D0 (en) | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
JP2005524672A (ja) | 2002-03-09 | 2005-08-18 | アストラゼネカ アクチボラグ | Cdk阻害活性を有するイミダゾリル置換ピリミジン誘導体 |
GB0205688D0 (en) * | 2002-03-09 | 2002-04-24 | Astrazeneca Ab | Chemical compounds |
GB0215844D0 (en) * | 2002-07-09 | 2002-08-14 | Novartis Ag | Organic compounds |
GB0311276D0 (en) * | 2003-05-16 | 2003-06-18 | Astrazeneca Ab | Chemical compounds |
PL1682528T3 (pl) | 2003-11-07 | 2008-01-31 | Hoffmann La Roche | Pochodne benzo[b][1,4]dioksepiny |
CN1906188A (zh) * | 2004-01-09 | 2007-01-31 | 诺瓦提斯公司 | 作为igf-1r抑制剂的苯基-[4-(3-苯基-1h-吡唑-4-基)-嘧啶-2-基]-胺衍生物 |
JP2008514571A (ja) * | 2004-09-29 | 2008-05-08 | バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト | 細胞周期−キナーゼまたはレセプター−チロシン−キナーゼインヒビターとしての置換2−置換アニリノピリミジン類、それらの製造および薬剤としての使用 |
MX2007004488A (es) * | 2004-10-13 | 2007-09-11 | Wyeth Corp | Analogos de anilino-pirimidina n-bencenosulfonilo sustituidos. |
KR20080033450A (ko) * | 2005-07-30 | 2008-04-16 | 아스트라제네카 아베 | 증식성 질환의 치료에 사용하기 위한 이미다졸릴-피리미딘화합물 |
-
2006
- 2006-07-27 KR KR1020087004572A patent/KR20080033450A/ko not_active Application Discontinuation
- 2006-07-27 JP JP2008514205A patent/JP4278172B2/ja not_active Expired - Fee Related
- 2006-07-27 MX MX2008001428A patent/MX2008001428A/es not_active Application Discontinuation
- 2006-07-27 US US11/995,159 patent/US20080280906A1/en not_active Abandoned
- 2006-07-27 CA CA002617170A patent/CA2617170A1/en not_active Abandoned
- 2006-07-27 AU AU2006274733A patent/AU2006274733B2/en not_active Ceased
- 2006-07-27 WO PCT/GB2006/002801 patent/WO2007015064A1/en active Application Filing
- 2006-07-27 BR BRPI0614502-7A patent/BRPI0614502A2/pt not_active IP Right Cessation
- 2006-07-27 EP EP10184712A patent/EP2301928A1/en not_active Withdrawn
- 2006-07-27 EP EP06765122A patent/EP1912974A1/en not_active Withdrawn
- 2006-07-28 UY UY29709A patent/UY29709A1/es not_active Application Discontinuation
- 2006-07-28 AR ARP060103296A patent/AR054879A1/es not_active Application Discontinuation
- 2006-07-28 TW TW095127608A patent/TW200738686A/zh unknown
-
2007
- 2007-12-24 IL IL188390A patent/IL188390A0/en unknown
-
2008
- 2008-01-04 NO NO20080061A patent/NO20080061L/no not_active Application Discontinuation
-
2009
- 2009-01-09 JP JP2009003310A patent/JP2009137990A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP4278172B2 (ja) | 2009-06-10 |
NO20080061L (no) | 2008-04-07 |
CA2617170A1 (en) | 2007-02-08 |
TW200738686A (en) | 2007-10-16 |
KR20080033450A (ko) | 2008-04-16 |
AU2006274733A1 (en) | 2007-02-08 |
BRPI0614502A2 (pt) | 2011-03-29 |
US20080280906A1 (en) | 2008-11-13 |
AR054879A1 (es) | 2007-07-25 |
EP2301928A1 (en) | 2011-03-30 |
JP2009137990A (ja) | 2009-06-25 |
EP1912974A1 (en) | 2008-04-23 |
MX2008001428A (es) | 2008-04-04 |
JP2008542350A (ja) | 2008-11-27 |
WO2007015064A1 (en) | 2007-02-08 |
IL188390A0 (en) | 2008-04-13 |
AU2006274733B2 (en) | 2010-09-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20161205 |