SE0102439D0 - New compounds - Google Patents
New compoundsInfo
- Publication number
- SE0102439D0 SE0102439D0 SE0102439A SE0102439A SE0102439D0 SE 0102439 D0 SE0102439 D0 SE 0102439D0 SE 0102439 A SE0102439 A SE 0102439A SE 0102439 A SE0102439 A SE 0102439A SE 0102439 D0 SE0102439 D0 SE 0102439D0
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- SE
- Sweden
- Prior art keywords
- sup
- new compounds
- active compounds
- new
- compounds
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
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- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
Priority Applications (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0102439A SE0102439D0 (sv) | 2001-07-05 | 2001-07-05 | New compounds |
RU2004102389/04A RU2004102389A (ru) | 2001-07-05 | 2002-07-03 | Ариламины для лечения состояний, ассоциированных с киназой-3 гликогенсинтазы (gsk-3) |
BR0210838-0A BR0210838A (pt) | 2001-07-05 | 2002-07-03 | Composto, formulação farmacêutica, uso de um composto, métodos de prevenção e/ou tratamento de condições associadas com glicogênio sintase quinase-3, e de doenças, e medicação contraceptiva, e, processos para a preparação de um composto |
PL02367782A PL367782A1 (en) | 2001-07-05 | 2002-07-03 | Arylamines for the treatment of conditions associated with gsk-3 |
CNA028135458A CN1551869A (zh) | 2001-07-05 | 2002-07-03 | 新化合物 |
IL15934702A IL159347A0 (en) | 2001-07-05 | 2002-07-03 | Arylamines for the treatment of conditions associated with gsk-3 |
JP2003510640A JP2005505515A (ja) | 2001-07-05 | 2002-07-03 | Gsk−3に関連する病態の治療のためのアリールアミン |
PCT/SE2002/001339 WO2003004472A1 (en) | 2001-07-05 | 2002-07-03 | Arylamines for the treatment of conditions associated with gsk-3 |
EP02747795A EP1414801A1 (en) | 2001-07-05 | 2002-07-03 | Arylamines for the treatment of conditions associated with gsk-3 |
MXPA03011972A MXPA03011972A (es) | 2001-07-05 | 2002-07-03 | Arilaminas para tratamiento de condiciones asociadas con gsk-3. |
KR10-2004-7000080A KR20040013102A (ko) | 2001-07-05 | 2002-07-03 | Gsk-3와 관련된 질환의 치료를 위한 아릴아민 |
CA002452686A CA2452686A1 (en) | 2001-07-05 | 2002-07-03 | Arylamines for the treatment of conditions associated with gsk-3 |
US10/481,721 US20060052396A1 (en) | 2001-07-05 | 2002-07-03 | Arylamines for the treatment of conditions associated with gsk-3 |
HU0500339A HUP0500339A2 (hu) | 2001-07-05 | 2002-07-03 | GSK3-mal kapcsolatos állapotok kezelésére használható aril-aminok, eljárás előállításukra, az ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk |
ARP020102533A AR036132A1 (es) | 2001-07-05 | 2002-07-05 | Pirazinas, formulacion farmaceutica, uso de estos compuestos en la fabricacion de medicamentos, procesos para la preparacion de estos compuestos e intermediarios |
ZA200309977A ZA200309977B (en) | 2001-07-05 | 2003-12-23 | Arylamines for the treatment of conditions associated with GSK-3. |
CO03113306A CO5540341A2 (es) | 2001-07-05 | 2003-12-30 | Arilaminas para el tratamiento de condiciones asociadas con gsk-3 |
IS7095A IS7095A (is) | 2001-07-05 | 2003-12-31 | Arýlamín til meðhöndlunar á ástandi sem tengist GSK-3 |
NO20040014A NO20040014L (no) | 2001-07-05 | 2004-01-02 | Nye forbindelser |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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SE0102439A SE0102439D0 (sv) | 2001-07-05 | 2001-07-05 | New compounds |
Publications (1)
Publication Number | Publication Date |
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SE0102439D0 true SE0102439D0 (sv) | 2001-07-05 |
Family
ID=20284777
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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SE0102439A SE0102439D0 (sv) | 2001-07-05 | 2001-07-05 | New compounds |
Country Status (19)
Country | Link |
---|---|
US (1) | US20060052396A1 (sv) |
EP (1) | EP1414801A1 (sv) |
JP (1) | JP2005505515A (sv) |
KR (1) | KR20040013102A (sv) |
CN (1) | CN1551869A (sv) |
AR (1) | AR036132A1 (sv) |
BR (1) | BR0210838A (sv) |
CA (1) | CA2452686A1 (sv) |
CO (1) | CO5540341A2 (sv) |
HU (1) | HUP0500339A2 (sv) |
IL (1) | IL159347A0 (sv) |
IS (1) | IS7095A (sv) |
MX (1) | MXPA03011972A (sv) |
NO (1) | NO20040014L (sv) |
PL (1) | PL367782A1 (sv) |
RU (1) | RU2004102389A (sv) |
SE (1) | SE0102439D0 (sv) |
WO (1) | WO2003004472A1 (sv) |
ZA (1) | ZA200309977B (sv) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6455587B1 (en) * | 2000-03-15 | 2002-09-24 | Pharmacor Inc. | Amino acid derivatives as HIV aspartyl protease inhibitors |
EP1501514B1 (en) * | 2002-05-03 | 2012-12-19 | Exelixis, Inc. | Protein kinase modulators and methods of use |
US7704995B2 (en) | 2002-05-03 | 2010-04-27 | Exelixis, Inc. | Protein kinase modulators and methods of use |
ES2263058T3 (es) | 2002-08-19 | 2006-12-01 | Glaxo Group Limited | Derivados de pirimidina como inhibidores selectivos de cox-2. |
GB0221443D0 (en) | 2002-09-16 | 2002-10-23 | Glaxo Group Ltd | Pyridine derivates |
SE0203754D0 (sv) * | 2002-12-17 | 2002-12-17 | Astrazeneca Ab | New compounds |
SE0203752D0 (sv) * | 2002-12-17 | 2002-12-17 | Astrazeneca Ab | New compounds |
BRPI0408251A (pt) | 2003-03-11 | 2006-03-01 | Pfizer Prod Inc | compostos de pirazina como inibidores do fator de crescimento transformante (tgf) |
JP4058368B2 (ja) * | 2003-03-27 | 2008-03-05 | ジーイー・メディカル・システムズ・グローバル・テクノロジー・カンパニー・エルエルシー | 超音波診断装置 |
CN1989131A (zh) | 2004-03-30 | 2007-06-27 | 希龙公司 | 取代的噻吩衍生物用作抗癌药 |
PL1786785T3 (pl) | 2004-08-26 | 2010-08-31 | Pfizer | Enancjomerycznie czyste związki aminoheteroarylowe jako kinazy białkowe |
CN101018780B (zh) * | 2004-08-26 | 2012-01-11 | 辉瑞大药厂 | 作为蛋白激酶抑制剂的吡唑取代的氨基杂芳基化合物 |
CA2587642C (en) | 2004-11-30 | 2013-04-09 | Amgen Inc. | Substituted heterocycles and methods of use |
JO2787B1 (en) | 2005-04-27 | 2014-03-15 | امجين إنك, | Alternative amide derivatives and methods of use |
EP1885454A2 (en) | 2005-05-04 | 2008-02-13 | DeveloGen Aktiengesellschaft | Use of gsk-3 inhibitors for preventing and treating pancreatic autoimmune disorders |
EP1749523A1 (en) * | 2005-07-29 | 2007-02-07 | Neuropharma, S.A. | GSK-3 inhibitors |
AU2006274733B2 (en) | 2005-07-30 | 2010-09-16 | Astrazeneca Ab | Imidazolyl-pyrimidine compounds for use in the treatment of proliferative disorders |
AR058073A1 (es) | 2005-10-03 | 2008-01-23 | Astrazeneca Ab | Derivados de imidazol 5-il-pirimidina, procesos de obtencion, composiciones farmaceuticas y usos |
TW200730512A (en) * | 2005-12-12 | 2007-08-16 | Astrazeneca Ab | Novel compounds |
AU2007221207A1 (en) | 2006-02-28 | 2007-09-07 | Merck Sharp & Dohme Corp. | Inhibitors of histone deacetylase |
TW200800203A (en) * | 2006-03-08 | 2008-01-01 | Astrazeneca Ab | New use |
CA2645487A1 (en) | 2006-03-23 | 2007-10-04 | Amgen Inc. | 1-phenylsulfonyl-diaza heterocyclic amide compounds and their uses as modulators of hydroxsteroid dehydrogenases |
MX2009004140A (es) | 2006-10-21 | 2009-07-10 | Abbott Gmbh & Co Kg | Compuestos heterociclicos y su uso como inhibidores de la glucogeno sintasa quinasa 3. |
WO2008063888A2 (en) | 2006-11-22 | 2008-05-29 | Plexxikon, Inc. | Compounds modulating c-fms and/or c-kit activity and uses therefor |
MX2009008253A (es) * | 2007-01-31 | 2009-10-12 | Vertex Pharma | Derivados de 2-aminopiridina utiles como inhibidores de cinasa. |
US20100190777A1 (en) | 2007-07-17 | 2010-07-29 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
TWI469782B (zh) * | 2007-10-31 | 2015-01-21 | Abbvie Deutschland | 適合用於治療對多巴胺d3受體之調節有反應的疾病之苯磺醯胺化合物 |
WO2010045095A1 (en) | 2008-10-14 | 2010-04-22 | Ning Xi | Compounds and methods of use |
EP2370424A1 (en) | 2008-11-10 | 2011-10-05 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
RU2604066C2 (ru) * | 2008-12-19 | 2016-12-10 | Вертекс Фармасьютикалз Инкорпорейтед | Производные пиразина, используемые в качестве ингибиторов киназы atr |
MX2011009926A (es) * | 2009-03-21 | 2012-01-27 | Ning Xi | Derivados de amino esteres, sales de los mismos, y metodos de uso. |
MX2011008303A (es) | 2009-04-03 | 2011-11-29 | Plexxikon Inc | Composiciones del acido propano-1-sulfonico {3-[5-(4-cloro-fenil)- 1h-pirrolo [2,3-b]-piridina-3-carbonil]-2,4-difluoro-fenil}-amida y el uso de las mismas. |
AU2010315126B2 (en) | 2009-11-06 | 2015-06-25 | Plexxikon, Inc. | Compounds and methods for kinase modulation, and indications therefor |
CN102812017A (zh) | 2010-01-19 | 2012-12-05 | 阿斯利康(瑞典)有限公司 | 吡嗪衍生物 |
JP2013526539A (ja) | 2010-05-12 | 2013-06-24 | バーテックス ファーマシューティカルズ インコーポレイテッド | Atrキナーゼ阻害剤として有用なピラジン |
JP2013526538A (ja) | 2010-05-12 | 2013-06-24 | バーテックス ファーマシューティカルズ インコーポレイテッド | Atrキナーゼ阻害剤として有用な化合物 |
MX2012013082A (es) | 2010-05-12 | 2013-05-09 | Vertex Pharma | Derivados de 2-aminopiridina utiles como iinhibidores de cinasa atr. |
US9334244B2 (en) | 2010-05-12 | 2016-05-10 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
US9630956B2 (en) | 2010-05-12 | 2017-04-25 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
US9062008B2 (en) | 2010-05-12 | 2015-06-23 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
EP2585468A1 (en) | 2010-06-23 | 2013-05-01 | Vertex Pharmaceuticals Incorporated | Pyrrolo- pyrazine derivatives useful as inhibitors of atr kinase |
US9266855B2 (en) | 2010-09-27 | 2016-02-23 | AbbVie Deutschland GmbH & Co. KG | Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors |
US9090592B2 (en) | 2010-12-30 | 2015-07-28 | AbbVie Deutschland GmbH & Co. KG | Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors |
AU2012214762B2 (en) | 2011-02-07 | 2015-08-13 | Plexxikon Inc. | Compounds and methods for kinase modulation, and indications therefor |
TWI558702B (zh) | 2011-02-21 | 2016-11-21 | 普雷辛肯公司 | 醫藥活性物質的固態形式 |
CN102718745A (zh) * | 2011-03-30 | 2012-10-10 | 中国科学院上海药物研究所 | 新型胺基吡啶类化合物、其制备方法、包含此类化合物的药物组合物及其用途 |
AU2012240030A1 (en) | 2011-04-05 | 2013-10-24 | Vertex Pharmaceuticals Incorporated | Aminopyrazine compounds useful as inhibitors of TRA kinase |
BR112013029640A2 (pt) * | 2011-05-23 | 2017-06-13 | Merck Patent Gmbh | derivados de piridina e pirazina |
US8822469B2 (en) | 2011-06-22 | 2014-09-02 | Vertex Pharmaceuticals Incorporated | Pyrrolo[2,3-B]pyrazines useful as inhibitors of ATR kinase |
JP2014517079A (ja) | 2011-06-22 | 2014-07-17 | バーテックス ファーマシューティカルズ インコーポレイテッド | Atrキナーゼ阻害剤として有用な化合物 |
EP2723747A1 (en) | 2011-06-22 | 2014-04-30 | Vertex Pharmaceuticals Inc. | Compounds useful as inhibitors of atr kinase |
WO2013049720A1 (en) | 2011-09-30 | 2013-04-04 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
EP2751088B1 (en) | 2011-09-30 | 2016-04-13 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
EP2751099B1 (en) | 2011-09-30 | 2017-06-14 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
SG11201401093WA (en) | 2011-09-30 | 2014-04-28 | Vertex Pharma | Processes for making compounds useful as inhibitors of atr kinase |
CN103957917A (zh) | 2011-09-30 | 2014-07-30 | 沃泰克斯药物股份有限公司 | 用atr抑制剂治疗胰腺癌和非小细胞肺癌 |
WO2013071093A1 (en) | 2011-11-09 | 2013-05-16 | Vertex Pharmaceuticals Incorporated | Pyrazine compounds useful as inhibitors of atr kinase |
WO2013071085A1 (en) | 2011-11-09 | 2013-05-16 | Vertex Pharmaceuticals Incorporated | Pyrazine compounds useful as inhibitors of atr kinase |
US8841337B2 (en) | 2011-11-09 | 2014-09-23 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of ATR kinase |
WO2013071088A1 (en) | 2011-11-09 | 2013-05-16 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
EP2776429A1 (en) | 2011-11-09 | 2014-09-17 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
RS56673B1 (sr) | 2012-04-05 | 2018-03-30 | Vertex Pharma | Jedinjenja korisna kao inhibitori atr kinaze i kombinovane terapije koje ih koriste |
US9150570B2 (en) | 2012-05-31 | 2015-10-06 | Plexxikon Inc. | Synthesis of heterocyclic compounds |
DK2904406T3 (en) | 2012-10-04 | 2018-06-18 | Vertex Pharma | METHOD OF DETERMINING THE ATR INHIBITION, INCREASED DNA DAMAGE |
EP2909202A1 (en) | 2012-10-16 | 2015-08-26 | Vertex Pharmaceuticals Incorporated | Compounds useful as inhibitors of atr kinase |
SI3808749T1 (sl) | 2012-12-07 | 2023-07-31 | Vertex Pharmaceuticals Incorporated | Pirazolo(1,5-A)pirimidini za uporabo kot zaviralci ATR kinaze pri zdravljenju rakavih bolezni |
JP2016512815A (ja) | 2013-03-15 | 2016-05-09 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | Atrキナーゼの阻害剤として有用な縮合ピラゾロピリミジン誘導体 |
RU2687276C2 (ru) | 2013-12-06 | 2019-05-13 | Вертекс Фармасьютикалз Инкорпорейтед | Соединения, пригодные для использования в качестве ингибиторов atr киназы |
NZ764151A (en) | 2014-06-05 | 2023-12-22 | Vertex Pharma | Radiolabelled derivatives of a 2-amino-6-fluoro-n-[5-fluoro-pyridin-3-yl]- pyrazolo[1,5-a]pyrimidin-3-carboxamide compound useful as atr kinase inhibitor, the preparation of said compound and different solid forms thereof |
CA2950780C (en) | 2014-06-17 | 2023-05-16 | Vertex Pharmaceuticals Incorporated | Method for treating cancer using a combination of chk1 and atr inhibitors |
JP2017524739A (ja) | 2014-07-17 | 2017-08-31 | アンセルムInserm | 神経筋接合部関連疾患の処置方法 |
JO3589B1 (ar) | 2014-08-06 | 2020-07-05 | Novartis Ag | مثبطات كيناز البروتين c وطرق استخداماتها |
WO2016207366A1 (en) | 2015-06-26 | 2016-12-29 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the treatment of viral infections |
EP3355926A4 (en) | 2015-09-30 | 2019-08-21 | Vertex Pharmaceuticals Inc. | METHOD FOR THE TREATMENT OF CANCER WITH A COMBINATION OF DNA DAMAGING AGENTS AND ATR INHIBITORS |
GB201519573D0 (en) | 2015-11-05 | 2015-12-23 | King S College London | Combination |
CN116211803A (zh) | 2016-01-11 | 2023-06-06 | 梅里麦克制药股份有限公司 | 抑制共济失调毛细血管扩张和Rad3相关蛋白(ATR) |
US20190177696A1 (en) | 2016-06-16 | 2019-06-13 | Ecole Polytechnique Federale De Lausanne (Epfl) | Method for preparing induced hepatic progenitor cells |
EA037520B1 (ru) | 2016-07-20 | 2021-04-07 | Новартис Аг | Производные аминопиридина и их применение в качестве селективных ингибиторов alk–2 |
TW201811766A (zh) | 2016-08-29 | 2018-04-01 | 瑞士商諾華公司 | N-(吡啶-2-基)吡啶-磺醯胺衍生物及其用於疾病治療之用途 |
AU2020218366A1 (en) | 2019-02-08 | 2021-09-16 | Frequency Therapeutics, Inc. | Valproic acid compounds and Wnt agonists for treating ear disorders |
EP4061367A1 (en) | 2019-11-22 | 2022-09-28 | Incyte Corporation | Combination therapy comprising an alk2 inhibitor and a jak2 inhibitor |
WO2021257532A1 (en) | 2020-06-16 | 2021-12-23 | Incyte Corporation | Alk2 inhibitors for the treatment of anemia |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5547004A (en) * | 1992-01-28 | 1996-08-20 | Klockner Hansel Tevopharm B.V. | Method and device for arranging a stream of products |
MA26473A1 (fr) * | 1997-03-01 | 2004-12-20 | Glaxo Group Ltd | Composes pharmacologiquement actifs. |
HUP0301573A3 (en) * | 2000-02-16 | 2004-03-29 | Neurogen Corp Branford | Substituted arylpyrazines, pharmaceutical compositions containing them and their use |
AR029489A1 (es) * | 2000-03-10 | 2003-07-02 | Euro Celtique Sa | Piridinas, pirimidinas, pirazinas, triazinas sustituidas por arilo, composiciones farmaceuticas y el uso de las mismas para la manufactura de un medicamento |
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2001
- 2001-07-05 SE SE0102439A patent/SE0102439D0/sv unknown
-
2002
- 2002-07-03 MX MXPA03011972A patent/MXPA03011972A/es unknown
- 2002-07-03 US US10/481,721 patent/US20060052396A1/en not_active Abandoned
- 2002-07-03 KR KR10-2004-7000080A patent/KR20040013102A/ko not_active Application Discontinuation
- 2002-07-03 EP EP02747795A patent/EP1414801A1/en not_active Withdrawn
- 2002-07-03 CA CA002452686A patent/CA2452686A1/en not_active Abandoned
- 2002-07-03 PL PL02367782A patent/PL367782A1/xx not_active Application Discontinuation
- 2002-07-03 WO PCT/SE2002/001339 patent/WO2003004472A1/en not_active Application Discontinuation
- 2002-07-03 CN CNA028135458A patent/CN1551869A/zh active Pending
- 2002-07-03 RU RU2004102389/04A patent/RU2004102389A/ru not_active Application Discontinuation
- 2002-07-03 BR BR0210838-0A patent/BR0210838A/pt not_active Application Discontinuation
- 2002-07-03 JP JP2003510640A patent/JP2005505515A/ja active Pending
- 2002-07-03 IL IL15934702A patent/IL159347A0/xx unknown
- 2002-07-03 HU HU0500339A patent/HUP0500339A2/hu unknown
- 2002-07-05 AR ARP020102533A patent/AR036132A1/es unknown
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2003
- 2003-12-23 ZA ZA200309977A patent/ZA200309977B/xx unknown
- 2003-12-30 CO CO03113306A patent/CO5540341A2/es not_active Application Discontinuation
- 2003-12-31 IS IS7095A patent/IS7095A/is unknown
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2004
- 2004-01-02 NO NO20040014A patent/NO20040014L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
NO20040014L (no) | 2004-03-02 |
CA2452686A1 (en) | 2003-01-16 |
CN1551869A (zh) | 2004-12-01 |
WO2003004472A8 (en) | 2003-03-13 |
IL159347A0 (en) | 2004-06-01 |
KR20040013102A (ko) | 2004-02-11 |
PL367782A1 (en) | 2005-03-07 |
HUP0500339A2 (hu) | 2005-07-28 |
EP1414801A1 (en) | 2004-05-06 |
BR0210838A (pt) | 2004-07-13 |
US20060052396A1 (en) | 2006-03-09 |
IS7095A (is) | 2003-12-31 |
WO2003004472A1 (en) | 2003-01-16 |
CO5540341A2 (es) | 2005-07-29 |
JP2005505515A (ja) | 2005-02-24 |
AR036132A1 (es) | 2004-08-11 |
RU2004102389A (ru) | 2005-07-10 |
ZA200309977B (en) | 2005-03-23 |
MXPA03011972A (es) | 2004-03-26 |
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