TR201819270T4 - Glikozaminoglikanlar Ve Siklodekstrinlerin Kombinasyonu - Google Patents
Glikozaminoglikanlar Ve Siklodekstrinlerin Kombinasyonu Download PDFInfo
- Publication number
- TR201819270T4 TR201819270T4 TR2018/19270T TR201819270T TR201819270T4 TR 201819270 T4 TR201819270 T4 TR 201819270T4 TR 2018/19270 T TR2018/19270 T TR 2018/19270T TR 201819270 T TR201819270 T TR 201819270T TR 201819270 T4 TR201819270 T4 TR 201819270T4
- Authority
- TR
- Turkey
- Prior art keywords
- combination
- cyclodextrins
- glycosaminoglycans
- therapy
- treatment
- Prior art date
Links
- 229920000858 Cyclodextrin Polymers 0.000 title abstract 2
- 229920002683 Glycosaminoglycan Polymers 0.000 title abstract 2
- 229940097362 cyclodextrins Drugs 0.000 title abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 abstract 1
- 229920001287 Chondroitin sulfate Polymers 0.000 abstract 1
- 229940059329 chondroitin sulfate Drugs 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Abstract
Bu buluş, hiyalüronik asit ve kondroitin sülfat olmak üzere iki spesifik glikozaminoglikan ile siklodekstrinlerin enjekte edilebilir bir kombinasyonuyla, ve bu kombinasyonun, iskelet sistemleriyle ilgili hastalıkların tedavisinin, özellikle eklem içi tedavinin yanı sıra deri içi tedavide kullanımı ile ilgilidir.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT002116A ITMI20132116A1 (it) | 2013-12-18 | 2013-12-18 | Associazione di glicosamminoglicani e ciclodestrine |
Publications (1)
Publication Number | Publication Date |
---|---|
TR201819270T4 true TR201819270T4 (tr) | 2019-01-21 |
Family
ID=50115999
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2018/19270T TR201819270T4 (tr) | 2013-12-18 | 2014-12-15 | Glikozaminoglikanlar Ve Siklodekstrinlerin Kombinasyonu |
Country Status (13)
Country | Link |
---|---|
US (1) | US9974803B2 (tr) |
EP (1) | EP3082869B1 (tr) |
CN (1) | CN105899233B (tr) |
BR (1) | BR112016013834B1 (tr) |
CA (1) | CA2932987C (tr) |
EA (1) | EA032372B1 (tr) |
ES (1) | ES2707971T3 (tr) |
IT (1) | ITMI20132116A1 (tr) |
MA (1) | MA39077A1 (tr) |
PT (1) | PT3082869T (tr) |
TN (1) | TN2016000206A1 (tr) |
TR (1) | TR201819270T4 (tr) |
WO (1) | WO2015092516A1 (tr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ITUB20153110A1 (it) * | 2015-08-13 | 2017-02-13 | Alfakjn S R L | Composizione liquida iniettabile per uso nella terapia infiltrativa intra-articolare |
IT201600075246A1 (it) | 2016-07-19 | 2018-01-19 | Jointherapeutics S R L | Composizioni comprendenti una matrice polisaccaridica per il rilascio controllato di principi attivi. |
IT201800010415A1 (it) * | 2018-11-19 | 2020-05-19 | Innate S R L | Composizione iniettabile comprendente acido ialuronico e trealosio e uso della detta composizione. |
KR20230019195A (ko) * | 2020-06-02 | 2023-02-07 | 내셔널 유니버시티 오브 싱가포르 | 조성물들, 요법에서 그것들의 용도들 및 이의 방법들 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SK282717B6 (sk) * | 2000-03-10 | 2002-11-06 | �Stav Experiment�Lnej Farmakol�Gie Sav | Spôsob prípravy ultravysokomolekulových hyalurónanov |
FR2811572B1 (fr) | 2000-07-17 | 2003-04-18 | Adir | Utilisation de cyclodextrines polysulfatees pour le traitement de l'arthrose |
MXPA01011542A (es) * | 2001-11-13 | 2003-05-22 | Alcon Inc | Regeneracion del cartilago articular da°ado por la osteoartritis de grado i y ii, mediante la aplicacion intra-articular de una mezcla de hialuronato de sodio y de condroitin sulfato en un vehiculo de gel. |
AU2003279835B2 (en) * | 2002-10-07 | 2009-09-10 | Zymogenetics, Inc. | Methods of administering FGF18 |
US8455458B2 (en) * | 2002-10-16 | 2013-06-04 | Arthrodynamic Technologies, Animal Health Division, Inc. | Composition and method for treating connective tissue damage |
CN1451369A (zh) * | 2003-03-13 | 2003-10-29 | 吉林大学 | 环糊精衍生物在化妆品中的应用 |
EP1967186B1 (en) * | 2005-12-27 | 2015-03-11 | Lion Corporation | Composition for soft contact lens and adsorption suppressing method |
CN100594029C (zh) * | 2006-07-24 | 2010-03-17 | 凌沛学 | 一种关节腔内注射用药物组合物 |
US8394784B2 (en) * | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having multi-stage bioactive agent delivery |
CN101259139A (zh) * | 2008-03-13 | 2008-09-10 | 北京阜康仁生物制药科技有限公司 | 一种用于消炎镇痛的药用组合物 |
KR20110067130A (ko) * | 2008-09-22 | 2011-06-21 | 아카리오스 비.브이. | 약제로서 유용한 카르복시에틸화 사이클로덱스트린 폴리설페이트 |
ITPD20120098A1 (it) * | 2012-03-30 | 2013-10-01 | Fidia Farmaceutici | "nuove formulazioni faramaceutiche contenenti condroitin solfato e derivati dell'acido ialuronico" |
CH705713B1 (de) * | 2012-09-21 | 2013-05-15 | Labo Cosprophar Ag | Dermokosmetische Zusammensetzung zur topischen Anwendung. |
CN103301118A (zh) * | 2013-06-27 | 2013-09-18 | 海南卫康制药(潜山)有限公司 | 注射用精氨酸布洛芬组合物 |
-
2013
- 2013-12-18 IT IT002116A patent/ITMI20132116A1/it unknown
-
2014
- 2014-12-15 TR TR2018/19270T patent/TR201819270T4/tr unknown
- 2014-12-15 ES ES14830561T patent/ES2707971T3/es active Active
- 2014-12-15 TN TN2016000206A patent/TN2016000206A1/en unknown
- 2014-12-15 US US15/105,595 patent/US9974803B2/en active Active
- 2014-12-15 MA MA39077A patent/MA39077A1/fr unknown
- 2014-12-15 WO PCT/IB2014/002774 patent/WO2015092516A1/en active Application Filing
- 2014-12-15 CN CN201480069024.0A patent/CN105899233B/zh active Active
- 2014-12-15 BR BR112016013834-1A patent/BR112016013834B1/pt active IP Right Grant
- 2014-12-15 CA CA2932987A patent/CA2932987C/en active Active
- 2014-12-15 PT PT14830561T patent/PT3082869T/pt unknown
- 2014-12-15 EP EP14830561.8A patent/EP3082869B1/en active Active
- 2014-12-15 EA EA201691246A patent/EA032372B1/ru unknown
Also Published As
Publication number | Publication date |
---|---|
EP3082869A1 (en) | 2016-10-26 |
BR112016013834B1 (pt) | 2022-11-22 |
EP3082869B1 (en) | 2018-10-31 |
CN105899233B (zh) | 2020-01-17 |
CA2932987C (en) | 2021-10-12 |
PT3082869T (pt) | 2019-02-06 |
ES2707971T3 (es) | 2019-04-08 |
MA39077A1 (fr) | 2017-11-30 |
CN105899233A (zh) | 2016-08-24 |
BR112016013834A2 (tr) | 2017-08-08 |
EA032372B1 (ru) | 2019-05-31 |
CA2932987A1 (en) | 2015-06-25 |
EA201691246A1 (ru) | 2016-10-31 |
TN2016000206A1 (en) | 2017-10-06 |
WO2015092516A1 (en) | 2015-06-25 |
ITMI20132116A1 (it) | 2015-06-19 |
US20170035799A1 (en) | 2017-02-09 |
US9974803B2 (en) | 2018-05-22 |
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