TR200002904T2 - Amidin bileşikleri - Google Patents

Amidin bileşikleri

Info

Publication number
TR200002904T2
TR200002904T2 TR2000/02904T TR200002904T TR200002904T2 TR 200002904 T2 TR200002904 T2 TR 200002904T2 TR 2000/02904 T TR2000/02904 T TR 2000/02904T TR 200002904 T TR200002904 T TR 200002904T TR 200002904 T2 TR200002904 T2 TR 200002904T2
Authority
TR
Turkey
Prior art keywords
compound
amidine compounds
salt
inhibitor
thrombosis
Prior art date
Application number
TR2000/02904T
Other languages
English (en)
Inventor
Katoh Susumu
Yokota Katsuyuki
Hayashi Mikio
Original Assignee
Japan Tobacco Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc. filed Critical Japan Tobacco Inc.
Publication of TR200002904T2 publication Critical patent/TR200002904T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)

Abstract

Tarifnamede tanimlandigi haliyle (I) formülünün bir bilesigi, bu bilesigin bir tuzu ya da ön-ilaci. Bu bulusun bilesigi, bu bilesigin bir tuzu ya da bir ön-ilaci Xa faktörü inhibitörü ve kan pihtilasma inhibitörü olarak kullanima yöneliktir ve bu maddeler, kan pihtilasmasi ya da trombozun neden oldugu hastaliklarin profilaksi ve/veya tedavisi için yararlidir.
TR2000/02904T 1998-04-10 1999-04-09 Amidin bileşikleri TR200002904T2 (tr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP11623398 1998-04-10
JP23786998 1998-08-25

Publications (1)

Publication Number Publication Date
TR200002904T2 true TR200002904T2 (tr) 2001-02-21

Family

ID=26454606

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02904T TR200002904T2 (tr) 1998-04-10 1999-04-09 Amidin bileşikleri

Country Status (23)

Country Link
US (2) US6562828B1 (tr)
EP (1) EP1070714B1 (tr)
KR (1) KR100416111B1 (tr)
CN (1) CN1305470A (tr)
AR (1) AR015269A1 (tr)
AT (1) ATE272630T1 (tr)
AU (1) AU752588B2 (tr)
BR (1) BR9910122A (tr)
CA (1) CA2327488A1 (tr)
CO (1) CO5021130A1 (tr)
DE (1) DE69919149D1 (tr)
HU (1) HUP0101137A3 (tr)
ID (1) ID28266A (tr)
IL (1) IL138899A0 (tr)
NO (1) NO20005083L (tr)
NZ (1) NZ508101A (tr)
PE (1) PE20000422A1 (tr)
PL (1) PL343424A1 (tr)
RU (1) RU2201927C2 (tr)
SG (1) SG74717A1 (tr)
SK (1) SK15072000A3 (tr)
TR (1) TR200002904T2 (tr)
WO (1) WO1999052895A1 (tr)

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US7544678B2 (en) * 2002-11-05 2009-06-09 The Trustees Of Columbia University In The City Of New York Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2)
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Also Published As

Publication number Publication date
HUP0101137A2 (hu) 2001-10-28
IL138899A0 (en) 2001-11-25
ATE272630T1 (de) 2004-08-15
CA2327488A1 (en) 1999-10-21
KR100416111B1 (ko) 2004-01-31
SK15072000A3 (sk) 2001-08-06
NO20005083D0 (no) 2000-10-09
NO20005083L (no) 2000-12-08
US20040006099A1 (en) 2004-01-08
EP1070714A9 (en) 2005-10-19
CO5021130A1 (es) 2001-03-27
US6562828B1 (en) 2003-05-13
NZ508101A (en) 2002-12-20
KR20010042606A (ko) 2001-05-25
ID28266A (id) 2001-05-10
HUP0101137A3 (en) 2003-03-28
EP1070714A4 (en) 2002-10-30
CN1305470A (zh) 2001-07-25
AU3167799A (en) 1999-11-01
EP1070714B1 (en) 2004-08-04
WO1999052895A1 (en) 1999-10-21
BR9910122A (pt) 2001-10-16
AR015269A1 (es) 2001-04-18
PL343424A1 (en) 2001-08-13
RU2201927C2 (ru) 2003-04-10
PE20000422A1 (es) 2000-05-19
DE69919149D1 (de) 2004-09-09
EP1070714A1 (en) 2001-01-24
SG74717A1 (en) 2000-08-22
AU752588B2 (en) 2002-09-26

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