DE60121461D1 - Kondensierte pyridoindolderivate - Google Patents
Kondensierte pyridoindolderivateInfo
- Publication number
- DE60121461D1 DE60121461D1 DE60121461T DE60121461T DE60121461D1 DE 60121461 D1 DE60121461 D1 DE 60121461D1 DE 60121461 T DE60121461 T DE 60121461T DE 60121461 T DE60121461 T DE 60121461T DE 60121461 D1 DE60121461 D1 DE 60121461D1
- Authority
- DE
- Germany
- Prior art keywords
- pyridoindol
- condensed
- derivatives
- compounds
- solvates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D515/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D515/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D515/14—Ortho-condensed systems
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US23773400P | 2000-10-03 | 2000-10-03 | |
US237734P | 2000-10-03 | ||
PCT/US2001/042175 WO2002028865A2 (en) | 2000-10-03 | 2001-09-17 | Condensed pyridoindole derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60121461D1 true DE60121461D1 (de) | 2006-08-24 |
DE60121461T2 DE60121461T2 (de) | 2007-02-08 |
Family
ID=22894936
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60121461T Expired - Lifetime DE60121461T2 (de) | 2000-10-03 | 2001-09-17 | Kondensierte pyridoindolderivate |
Country Status (10)
Country | Link |
---|---|
US (1) | US6858620B2 (de) |
EP (1) | EP1335923B1 (de) |
JP (1) | JP4246488B2 (de) |
AT (1) | ATE332903T1 (de) |
AU (1) | AU2002213421A1 (de) |
CA (1) | CA2423312A1 (de) |
DE (1) | DE60121461T2 (de) |
ES (1) | ES2267831T3 (de) |
MX (1) | MXPA03002911A (de) |
WO (1) | WO2002028865A2 (de) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7115621B2 (en) | 2001-04-25 | 2006-10-03 | Lilly Icos Llc | Chemical compounds |
RU2331438C2 (ru) | 2002-12-13 | 2008-08-20 | Уорнер-Ламберт Компани Ллс | Альфа-2-дельта лиганд для лечения симптомов нижних мочевыводящих путей |
EP1708718A1 (de) | 2004-01-22 | 2006-10-11 | Pfizer Limited | Triazol-derivate zur hemmung der vasopressing-antagonistischen aktivität |
CA2559545A1 (en) * | 2004-03-15 | 2005-09-29 | Ptc Therapeutics, Inc. | Tetra-cyclic carboline derivatives for inhibiting angiogenesis |
CN101106997A (zh) | 2004-08-17 | 2008-01-16 | 约翰·霍普金斯大学 | Pde5抑制剂组合物及治疗心脏病征候的方法 |
ATE486878T1 (de) | 2004-08-18 | 2010-11-15 | 4Sc Ag | Benzothienopyridine zur verwendung als inhibitoren von eg5-kinesin |
US20080114017A1 (en) * | 2005-01-27 | 2008-05-15 | Matthias Vennemann | Novel Indolopyridines, Benzofuranopyridines and Benzothienopyridines |
AU2006208710A1 (en) * | 2005-01-28 | 2006-08-03 | 4Sc Ag | Indolopyridines, benzofuranopyridines and benzothienopyridines |
EP2824105B1 (de) | 2006-02-22 | 2021-03-31 | 4Sc Ag | Indolopyridine als Eg5 Kinesin-Modulatoren |
FR2914924A1 (fr) * | 2007-04-13 | 2008-10-17 | Fourtillan Snc | Derives de 4,5,11,11a-tetrahydro-1h,6h-oxazolo[3',4': 1,6] pyrido[3,4-b]indol-3-one et leur utilisation en therapeutique. |
EP2240481A1 (de) | 2008-01-11 | 2010-10-20 | Albany Molecular Research, Inc. | (1-azinon)-substituierte pyridoindole als mch-antagonisten |
US20120283282A1 (en) * | 2009-06-18 | 2012-11-08 | Arleen Rifkind | Photoproducts of Tryptophan, Their Synthesis and Uses Thereof |
US9073925B2 (en) | 2009-07-01 | 2015-07-07 | Albany Molecular Research, Inc. | Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof |
WO2011003012A1 (en) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof |
US8637501B2 (en) | 2009-07-01 | 2014-01-28 | Albany Molecular Research, Inc. | Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine MCH-1 antagonists, methods of making, and use thereof |
US8629158B2 (en) | 2009-07-01 | 2014-01-14 | Albany Molecular Research, Inc. | Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof |
US8993765B2 (en) | 2010-12-21 | 2015-03-31 | Albany Molecular Research, Inc. | Tetrahydro-azacarboline MCH-1 antagonists, methods of making, and uses thereof |
WO2012088038A2 (en) | 2010-12-21 | 2012-06-28 | Albany Molecular Research, Inc. | Piperazinone-substituted tetrahydro-carboline mch-1 antagonists, methods of making, and uses thereof |
US9789126B2 (en) | 2012-12-21 | 2017-10-17 | Mayo Foundation For Medical Education And Research | Methods and materials for treating calcific aortic valve stenosis |
CN105764903B (zh) | 2013-11-22 | 2018-09-18 | 法玛克亚公司 | 四环自分泌运动因子抑制剂 |
PL3071561T3 (pl) | 2013-11-22 | 2021-11-08 | Sabre Therapeutics Llc | Związki inhibitora autotaksyny |
KR101895698B1 (ko) * | 2014-01-23 | 2018-09-05 | 아사히 가세이 가부시키가이샤 | 점접착제 조성물 및 점접착성 테이프 |
US10632104B2 (en) | 2015-05-27 | 2020-04-28 | Sabre Therapeutics Llc | Autotaxin inhibitors and uses thereof |
FI130627B (en) | 2021-03-31 | 2023-12-18 | Equinorm Ltd | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8420969D0 (en) * | 1984-08-17 | 1984-09-19 | Tanabe Seiyaku Co | Tetrahydro-beta-carboline derivative |
EP0357122A3 (de) | 1988-08-29 | 1991-10-23 | Duphar International Research B.V | Verwendung von Beta-Carbolinen und deren bio-isosterischen Benzofuran- und Benzothiophenanalogen zur Herstellung eines Arzneimittels mit cytostatischer Wirkung |
US5622960A (en) * | 1992-04-14 | 1997-04-22 | The United States Of America As Represented By The Department Of Health And Human Services | Topoisomerase II inhibitors and therapeutic uses therefor |
GB9514473D0 (en) | 1995-07-14 | 1995-09-13 | Glaxo Lab Sa | Chemical compounds |
-
2001
- 2001-09-17 CA CA002423312A patent/CA2423312A1/en not_active Abandoned
- 2001-09-17 AT AT01981804T patent/ATE332903T1/de not_active IP Right Cessation
- 2001-09-17 EP EP01981804A patent/EP1335923B1/de not_active Expired - Lifetime
- 2001-09-17 ES ES01981804T patent/ES2267831T3/es not_active Expired - Lifetime
- 2001-09-17 DE DE60121461T patent/DE60121461T2/de not_active Expired - Lifetime
- 2001-09-17 AU AU2002213421A patent/AU2002213421A1/en not_active Abandoned
- 2001-09-17 WO PCT/US2001/042175 patent/WO2002028865A2/en active IP Right Grant
- 2001-09-17 MX MXPA03002911A patent/MXPA03002911A/es active IP Right Grant
- 2001-09-17 JP JP2002532448A patent/JP4246488B2/ja not_active Expired - Fee Related
- 2001-09-17 US US10/363,528 patent/US6858620B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2423312A1 (en) | 2002-04-11 |
JP2004511448A (ja) | 2004-04-15 |
JP4246488B2 (ja) | 2009-04-02 |
WO2002028865A3 (en) | 2003-02-27 |
US20040082787A1 (en) | 2004-04-29 |
DE60121461T2 (de) | 2007-02-08 |
MXPA03002911A (es) | 2003-09-10 |
US6858620B2 (en) | 2005-02-22 |
AU2002213421A1 (en) | 2002-04-15 |
EP1335923A2 (de) | 2003-08-20 |
ES2267831T3 (es) | 2007-03-16 |
EP1335923B1 (de) | 2006-07-12 |
WO2002028865A2 (en) | 2002-04-11 |
ATE332903T1 (de) | 2006-08-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |