ATE272630T1 - Amidin-verbindungen - Google Patents

Amidin-verbindungen

Info

Publication number
ATE272630T1
ATE272630T1 AT99913608T AT99913608T ATE272630T1 AT E272630 T1 ATE272630 T1 AT E272630T1 AT 99913608 T AT99913608 T AT 99913608T AT 99913608 T AT99913608 T AT 99913608T AT E272630 T1 ATE272630 T1 AT E272630T1
Authority
AT
Austria
Prior art keywords
amidine compounds
amidine
compounds
Prior art date
Application number
AT99913608T
Other languages
English (en)
Inventor
Susumu Katoh
Katsuyuki Yokota
Mikio Hayashi
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Application granted granted Critical
Publication of ATE272630T1 publication Critical patent/ATE272630T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT99913608T 1998-04-10 1999-04-09 Amidin-verbindungen ATE272630T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP11623398 1998-04-10
JP23786998 1998-08-25
PCT/JP1999/001900 WO1999052895A1 (en) 1998-04-10 1999-04-09 Amidine compounds

Publications (1)

Publication Number Publication Date
ATE272630T1 true ATE272630T1 (de) 2004-08-15

Family

ID=26454606

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99913608T ATE272630T1 (de) 1998-04-10 1999-04-09 Amidin-verbindungen

Country Status (23)

Country Link
US (2) US6562828B1 (de)
EP (1) EP1070714B1 (de)
KR (1) KR100416111B1 (de)
CN (1) CN1305470A (de)
AR (1) AR015269A1 (de)
AT (1) ATE272630T1 (de)
AU (1) AU752588B2 (de)
BR (1) BR9910122A (de)
CA (1) CA2327488A1 (de)
CO (1) CO5021130A1 (de)
DE (1) DE69919149D1 (de)
HU (1) HUP0101137A3 (de)
ID (1) ID28266A (de)
IL (1) IL138899A0 (de)
NO (1) NO20005083L (de)
NZ (1) NZ508101A (de)
PE (1) PE20000422A1 (de)
PL (1) PL343424A1 (de)
RU (1) RU2201927C2 (de)
SG (1) SG74717A1 (de)
SK (1) SK15072000A3 (de)
TR (1) TR200002904T2 (de)
WO (1) WO1999052895A1 (de)

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US6350761B1 (en) 1999-07-30 2002-02-26 Berlex Laboratories, Inc. Benzenamine derivatives as anti-coagulants
US20020065303A1 (en) * 2000-02-01 2002-05-30 Bing-Yan Zhu Bivalent phenylene inhibitors of factor Xa
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WO2001072712A1 (en) * 2000-03-24 2001-10-04 Cor Therapeutics, Inc. ISOQUINOLONE INHIBITORS OF FACTOR Xa
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US20040229781A1 (en) * 2000-05-10 2004-11-18 Marks Andrew Robert Compounds and methods for treating and preventing exercise-induced cardiac arrhythmias
US20060293266A1 (en) * 2000-05-10 2006-12-28 The Trustees Of Columbia Phosphodiesterase 4D in the ryanodine receptor complex protects against heart failure
US20040048780A1 (en) * 2000-05-10 2004-03-11 The Trustees Of Columbia University In The City Of New York Method for treating and preventing cardiac arrhythmia
US7718644B2 (en) * 2004-01-22 2010-05-18 The Trustees Of Columbia University In The City Of New York Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof
US7879840B2 (en) * 2005-08-25 2011-02-01 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US6489125B1 (en) * 2000-05-10 2002-12-03 The Trustees Of Columbia University In The City Of New York Methods for identifying chemical compounds that inhibit dissociation of FKBP12.6 binding protein from type 2 ryanodine receptor
US8022058B2 (en) 2000-05-10 2011-09-20 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
EP1302462A4 (de) * 2000-07-17 2007-07-18 Takeda Pharmaceutical Sulfonderivate, verfahren zu ihrer herstellung und ihre verwendung
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US7544678B2 (en) * 2002-11-05 2009-06-09 The Trustees Of Columbia University In The City Of New York Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2)
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US7741341B2 (en) * 2003-05-19 2010-06-22 Sanofi-Aventis Deutschland Gmbh Benzimidazole-derivatives as factor Xa inhibitors
EP1479676A1 (de) * 2003-05-19 2004-11-24 Aventis Pharma Deutschland GmbH Benzimidazolderivate als Faktor Xa-Inhibitoren
US7378409B2 (en) 2003-08-21 2008-05-27 Bristol-Myers Squibb Company Substituted cycloalkylamine derivatives as modulators of chemokine receptor activity
JP4355917B2 (ja) 2003-10-29 2009-11-04 信越化学工業株式会社 含窒素有機化合物、レジスト材料及びパターン形成方法
US8710045B2 (en) * 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
DE102004016605A1 (de) * 2004-04-03 2005-10-20 Merck Patent Gmbh Thiocarbamoylproline
TWI396686B (zh) * 2004-05-21 2013-05-21 Takeda Pharmaceutical 環狀醯胺衍生物、以及其製品和用法
FR2870846B1 (fr) 2004-05-25 2006-08-04 Sanofi Synthelabo Derives de tetrahydroisoquinolylsulfonamides, leur preparation et leur utilisation en therapeutique
RU2391340C2 (ru) * 2004-08-11 2010-06-10 Киорин Фармасьютикал Ко., Лтд. Новое циклическое производное аминобензойной кислоты
JP4900238B2 (ja) 2005-02-02 2012-03-21 味の素株式会社 新規ベンズアミジン化合物
US20090036489A1 (en) * 2005-03-22 2009-02-05 Masahiro Nomura Novel Cyclic Aminophenylalkanoic Acid Derivative
US7709516B2 (en) * 2005-06-17 2010-05-04 Endorecherche, Inc. Helix 12 directed non-steroidal antiandrogens
US7704990B2 (en) * 2005-08-25 2010-04-27 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
EP1790646A1 (de) * 2005-11-24 2007-05-30 Sanofi-Aventis Isoquinolin- und Benzo[h]isoquinolinderivate, deren Herstellung und deren therapeutischen Verwendung als Antagonisten des Histamin-H3-Rezeptors .
US20080186971A1 (en) * 2007-02-02 2008-08-07 Tarari, Inc. Systems and methods for processing access control lists (acls) in network switches using regular expression matching logic
JPWO2010005087A1 (ja) 2008-07-11 2012-01-05 味の素株式会社 アミジン誘導体
AR080374A1 (es) 2010-03-05 2012-04-04 Sanofi Aventis Procedimiento para la preparcion de 2-(ciclohexilmetil)-n-(2-((2s)-1-metilpirrolidin-2-il) etil)- 1,2,3,4-tetrahidroisoquinolin-7- sulfonamida
KR101499696B1 (ko) * 2013-10-16 2015-03-09 한국식품연구원 젓갈 유래 엔테로코쿠스속 미생물 및 이를 이용하여 s-아데노실-l-메티오닌을 대량 생산하는 방법
CN103965113A (zh) * 2014-05-06 2014-08-06 四川大学 1-羟乙基-2-取代苯氧甲基苯并咪唑类化合物及其制备方法
BR112020004857A2 (pt) * 2017-10-04 2020-09-15 Japan Tobacco, Inc. composto heteroarila contendo hidrogênio, e uso farmacêutico do mesmo

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Also Published As

Publication number Publication date
US6562828B1 (en) 2003-05-13
EP1070714A4 (de) 2002-10-30
CA2327488A1 (en) 1999-10-21
HUP0101137A3 (en) 2003-03-28
AU752588B2 (en) 2002-09-26
SG74717A1 (en) 2000-08-22
BR9910122A (pt) 2001-10-16
PL343424A1 (en) 2001-08-13
NZ508101A (en) 2002-12-20
RU2201927C2 (ru) 2003-04-10
CN1305470A (zh) 2001-07-25
AR015269A1 (es) 2001-04-18
TR200002904T2 (tr) 2001-02-21
SK15072000A3 (sk) 2001-08-06
WO1999052895A1 (en) 1999-10-21
IL138899A0 (en) 2001-11-25
EP1070714A1 (de) 2001-01-24
NO20005083D0 (no) 2000-10-09
NO20005083L (no) 2000-12-08
AU3167799A (en) 1999-11-01
HUP0101137A2 (hu) 2001-10-28
KR20010042606A (ko) 2001-05-25
US20040006099A1 (en) 2004-01-08
EP1070714B1 (de) 2004-08-04
CO5021130A1 (es) 2001-03-27
PE20000422A1 (es) 2000-05-19
DE69919149D1 (de) 2004-09-09
KR100416111B1 (ko) 2004-01-31
EP1070714A9 (de) 2005-10-19
ID28266A (id) 2001-05-10

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