SK284881B6 - Syntetické polysacharidy, spôsob ich prípravy a farmaceutické kompozície s ich obsahom - Google Patents

Syntetické polysacharidy, spôsob ich prípravy a farmaceutické kompozície s ich obsahom Download PDF

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Publication number
SK284881B6
SK284881B6 SK53-99A SK5399A SK284881B6 SK 284881 B6 SK284881 B6 SK 284881B6 SK 5399 A SK5399 A SK 5399A SK 284881 B6 SK284881 B6 SK 284881B6
Authority
SK
Slovakia
Prior art keywords
methyl
glucopyranosyl
sulfo
tri
mmol
Prior art date
Application number
SK53-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK5399A3 (en
Inventor
Pierre Alexandre Driguez
Philippe Duchaussoy
Jean-Marc Herbert
Maurice Petitou
Boeckel Constant Van
Peter Grootenhuis
Cornelia Dreef-Tromp
Johannes Basten
Original Assignee
Sanofi - Aventis
Akzo Nobel N. V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi - Aventis, Akzo Nobel N. V. filed Critical Sanofi - Aventis
Publication of SK5399A3 publication Critical patent/SK5399A3/sk
Publication of SK284881B6 publication Critical patent/SK284881B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
SK53-99A 1996-07-19 1997-07-18 Syntetické polysacharidy, spôsob ich prípravy a farmaceutické kompozície s ich obsahom SK284881B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9609116A FR2751334B1 (fr) 1996-07-19 1996-07-19 Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
PCT/FR1997/001344 WO1998003554A1 (fr) 1996-07-19 1997-07-18 Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
SK5399A3 SK5399A3 (en) 2000-05-16
SK284881B6 true SK284881B6 (sk) 2006-02-02

Family

ID=9494266

Family Applications (1)

Application Number Title Priority Date Filing Date
SK53-99A SK284881B6 (sk) 1996-07-19 1997-07-18 Syntetické polysacharidy, spôsob ich prípravy a farmaceutické kompozície s ich obsahom

Country Status (36)

Country Link
US (1) US6534481B1 (id)
EP (1) EP0912613B1 (id)
JP (1) JP3345020B2 (id)
KR (1) KR100311857B1 (id)
CN (1) CN1200003C (id)
AR (1) AR008068A1 (id)
AT (1) ATE224917T1 (id)
AU (1) AU726679B2 (id)
BR (1) BR9710739B1 (id)
CA (1) CA2261597C (id)
CZ (1) CZ301009B6 (id)
DE (1) DE69715866T2 (id)
DK (1) DK0912613T3 (id)
EE (1) EE03929B1 (id)
ES (1) ES2184123T3 (id)
FR (1) FR2751334B1 (id)
HK (1) HK1019757A1 (id)
HU (1) HU223691B1 (id)
ID (1) ID20604A (id)
IL (2) IL128018A0 (id)
IS (1) IS1968B (id)
MY (1) MY124548A (id)
NO (1) NO319682B1 (id)
NZ (1) NZ333721A (id)
PL (1) PL190397B1 (id)
PT (1) PT912613E (id)
RU (1) RU2167163C2 (id)
SA (1) SA99200037B1 (id)
SI (1) SI0912613T1 (id)
SK (1) SK284881B6 (id)
TR (1) TR199900114T2 (id)
TW (1) TW520376B (id)
UA (1) UA61921C2 (id)
WO (1) WO1998003554A1 (id)
YU (1) YU49247B (id)
ZA (1) ZA976340B (id)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2773801B1 (fr) 1998-01-19 2000-05-12 Sanofi Sa Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
US7138531B2 (en) * 2001-10-15 2006-11-21 Kemin Pharma B.V.B.A. Preparation and use of carbohydrate-based bicyclic ring structures with antimicrobial and cytostatic activity
EP1574516A1 (en) * 2004-03-05 2005-09-14 Sanofi-Aventis Antithrombotic compound
US7563780B1 (en) * 2004-06-18 2009-07-21 Advanced Cardiovascular Systems, Inc. Heparin prodrugs and drug delivery stents formed therefrom
FR2874924B1 (fr) * 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) * 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) * 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
IL181431A0 (en) * 2007-02-19 2007-07-04 Micha Shemer Fruit juice and puree with a lowered amount of available sugars
CN101874035B (zh) 2007-10-16 2014-12-03 普罗吉恩制药有限公司 新的硫酸化寡糖衍生物
CN102046781A (zh) 2008-05-30 2011-05-04 动量制药公司 糖结构以及制造和使用此类结构的方法
FR2935386B1 (fr) * 2008-08-26 2010-09-10 Sanofi Aventis Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine
EP3666786A1 (en) * 2009-07-31 2020-06-17 Reliable Biopharmaceutical Corporation Process for preparing fondaparinux sodium and intermediates useful in the synthesis thereof
FR2949114B1 (fr) 2009-08-14 2011-08-26 Sanofi Aventis OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2949115B1 (fr) 2009-08-14 2012-11-02 Sanofi Aventis OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
KR101682466B1 (ko) * 2010-02-01 2016-12-05 롯데정밀화학 주식회사 아세틸화 셀룰로오스 에테르 및 이를 포함하는 물품
JP2013537181A (ja) 2010-09-10 2013-09-30 サノフイ 抗血栓活性及び改善された代謝安定性を有するビオチン化多糖類
FR2970969B1 (fr) 2011-01-27 2013-10-18 Sanofi Aventis Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique
CN109134555B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途
CN109134554B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途
CN109134553B (zh) * 2017-06-15 2021-09-28 南京正大天晴制药有限公司 抗凝血的五糖类化合物及其制备方法和医药用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4801583A (en) 1982-01-15 1989-01-31 Choay S.A. Oligosaccharides and their biological applications
EP0300099A1 (en) 1987-07-20 1989-01-25 Akzo N.V. New pentasaccharides
US5378829A (en) 1990-04-23 1995-01-03 Akzo N.V. Sulfated glycosaminoglycanoid derivatives of the heparin and heparan sulfate type
US5382570A (en) 1990-04-23 1995-01-17 Akzo, N.V. Sulfated glycosaminoglycanoid derivatives of the dermatan sulfate and chondroitin sulfate type
IL102758A (en) 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
FR2704226B1 (fr) 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
ES2147216T3 (es) 1993-09-01 2000-09-01 Akzo Nobel Nv Bisconjugados que comprenden dos sacaridos y un grupo de union.
FR2749849B1 (fr) * 1996-06-14 1998-09-04 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
YU49247B (sh) 2004-12-31
UA61921C2 (uk) 2003-12-15
WO1998003554A1 (fr) 1998-01-29
US6534481B1 (en) 2003-03-18
SI0912613T1 (en) 2003-04-30
KR20000067909A (ko) 2000-11-25
CZ16099A3 (cs) 1999-06-16
HU223691B1 (hu) 2004-12-28
SK5399A3 (en) 2000-05-16
CN1228785A (zh) 1999-09-15
NZ333721A (en) 2000-08-25
ES2184123T3 (es) 2003-04-01
NO990215L (no) 1999-03-18
AU726679B2 (en) 2000-11-16
IL128018A0 (en) 1999-11-30
SA99200037B1 (ar) 2006-08-23
EP0912613A1 (fr) 1999-05-06
ATE224917T1 (de) 2002-10-15
CA2261597C (fr) 2004-12-14
NO319682B1 (no) 2005-09-05
NO990215D0 (no) 1999-01-18
EE03929B1 (et) 2002-12-16
BR9710739A (pt) 1999-08-17
KR100311857B1 (ko) 2001-11-14
YU1999A (sh) 2000-03-21
BR9710739B1 (pt) 2008-11-18
IS4945A (is) 1999-01-18
CZ301009B6 (cs) 2009-10-14
ZA976340B (en) 1999-01-22
TW520376B (en) 2003-02-11
RU2167163C2 (ru) 2001-05-20
FR2751334A1 (fr) 1998-01-23
IL128018A (en) 2007-10-31
JP3345020B2 (ja) 2002-11-18
EP0912613B1 (fr) 2002-09-25
FR2751334B1 (fr) 1998-10-16
JP2000500807A (ja) 2000-01-25
PL331259A1 (en) 1999-07-05
IS1968B (is) 2004-12-15
EE9900015A (et) 1999-08-16
HUP9902287A1 (hu) 1999-10-28
DE69715866T2 (de) 2003-05-28
CN1200003C (zh) 2005-05-04
MY124548A (en) 2006-06-30
DE69715866D1 (de) 2002-10-31
HUP9902287A3 (en) 2001-09-28
CA2261597A1 (fr) 1998-01-29
HK1019757A1 (en) 2000-02-25
DK0912613T3 (da) 2003-01-27
TR199900114T2 (xx) 1999-03-22
PT912613E (pt) 2003-01-31
AU3774797A (en) 1998-02-10
AR008068A1 (es) 1999-12-09
ID20604A (id) 1999-01-21
PL190397B1 (pl) 2005-12-30

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Legal Events

Date Code Title Description
MK4A Patent expired

Expiry date: 20170718