SK281143B6 - Chimérická monoklonálna protilátka, expresné vektory a farmaceutický prostriedok - Google Patents

Chimérická monoklonálna protilátka, expresné vektory a farmaceutický prostriedok Download PDF

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Publication number
SK281143B6
SK281143B6 SK360-99A SK36099A SK281143B6 SK 281143 B6 SK281143 B6 SK 281143B6 SK 36099 A SK36099 A SK 36099A SK 281143 B6 SK281143 B6 SK 281143B6
Authority
SK
Slovakia
Prior art keywords
human
antibody
regions
region
antibodies
Prior art date
Application number
SK360-99A
Other languages
English (en)
Slovak (sk)
Inventor
Mary M. Bendig
Cathrine A. Kettleborough
Jos Saldanha
Original Assignee
Merck Patent Gesellschaft Mit Beschr�Nkter Haftung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gesellschaft Mit Beschr�Nkter Haftung filed Critical Merck Patent Gesellschaft Mit Beschr�Nkter Haftung
Publication of SK281143B6 publication Critical patent/SK281143B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/867—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody produced via recombinant dna technology

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SK360-99A 1991-03-06 1992-03-04 Chimérická monoklonálna protilátka, expresné vektory a farmaceutický prostriedok SK281143B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP91103389 1991-03-06
PCT/EP1992/000480 WO1992015683A1 (en) 1991-03-06 1992-03-04 Humanized and chimeric monoclonal antibodies

Publications (1)

Publication Number Publication Date
SK281143B6 true SK281143B6 (sk) 2000-12-11

Family

ID=8206486

Family Applications (2)

Application Number Title Priority Date Filing Date
SK360-99A SK281143B6 (sk) 1991-03-06 1992-03-04 Chimérická monoklonálna protilátka, expresné vektory a farmaceutický prostriedok
SK3327-92A SK281142B6 (sk) 1991-03-06 1992-03-04 Humanizovaná monoklonálna protilátka, expresné vektory a farmaceutický prostriedok

Family Applications After (1)

Application Number Title Priority Date Filing Date
SK3327-92A SK281142B6 (sk) 1991-03-06 1992-03-04 Humanizovaná monoklonálna protilátka, expresné vektory a farmaceutický prostriedok

Country Status (19)

Country Link
US (1) US5558864A (de)
EP (2) EP0531472B1 (de)
JP (1) JP3854306B2 (de)
KR (1) KR100240308B1 (de)
AT (1) ATE247168T1 (de)
AU (1) AU658396B2 (de)
CA (1) CA2082160C (de)
CZ (2) CZ282603B6 (de)
DE (1) DE69233153T2 (de)
DK (1) DK0531472T3 (de)
ES (1) ES2204890T3 (de)
HU (1) HU219537B (de)
IE (1) IE920705A1 (de)
MX (1) MX9201016A (de)
PT (1) PT100195B (de)
SK (2) SK281143B6 (de)
TW (1) TW222279B (de)
WO (1) WO1992015683A1 (de)
ZA (1) ZA921661B (de)

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