SI9200240A - New acylates from imidazole-5-carboxylic acid derivatives and process for their preparation and their use - Google Patents

New acylates from imidazole-5-carboxylic acid derivatives and process for their preparation and their use Download PDF

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Publication number
SI9200240A
SI9200240A SI9200240A SI9200240A SI9200240A SI 9200240 A SI9200240 A SI 9200240A SI 9200240 A SI9200240 A SI 9200240A SI 9200240 A SI9200240 A SI 9200240A SI 9200240 A SI9200240 A SI 9200240A
Authority
SI
Slovenia
Prior art keywords
compound
imidazole
formula
carboxylic acid
preparation
Prior art date
Application number
SI9200240A
Other languages
English (en)
Slovenian (sl)
Inventor
Dieter Binder
Josef Weinberger
Original Assignee
Chem Pharm Forsch Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Pharm Forsch Gmbh filed Critical Chem Pharm Forsch Gmbh
Publication of SI9200240A publication Critical patent/SI9200240A/sl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SI9200240A 1991-10-04 1992-10-02 New acylates from imidazole-5-carboxylic acid derivatives and process for their preparation and their use SI9200240A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0198791A AT398202B (de) 1991-10-04 1991-10-04 Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
SI9200240A true SI9200240A (en) 1993-06-30

Family

ID=3525398

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9200240A SI9200240A (en) 1991-10-04 1992-10-02 New acylates from imidazole-5-carboxylic acid derivatives and process for their preparation and their use

Country Status (22)

Country Link
US (1) US5298519A (sk)
EP (1) EP0535420A1 (sk)
JP (1) JP2544565B2 (sk)
CN (1) CN1032856C (sk)
AT (1) AT398202B (sk)
AU (1) AU649357B2 (sk)
CA (1) CA2079735A1 (sk)
CZ (1) CZ301992A3 (sk)
FI (1) FI924353A (sk)
HR (1) HRP920817A2 (sk)
HU (1) HUT62291A (sk)
IL (1) IL103329A (sk)
LV (1) LV10256B (sk)
MY (1) MY108350A (sk)
NO (1) NO923798L (sk)
NZ (1) NZ244320A (sk)
RU (1) RU2105764C1 (sk)
SI (1) SI9200240A (sk)
SK (1) SK301992A3 (sk)
TW (1) TW223073B (sk)
YU (1) YU48290B (sk)
ZA (1) ZA927205B (sk)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2105939B1 (es) * 1994-08-02 1998-07-01 Uriach & Cia Sa J Nuevos pirazoles con actividad antagonista de la angiotensina ii.
CN101024643A (zh) * 2006-02-20 2007-08-29 上海艾力斯医药科技有限公司 咪唑－5－羧酸类衍生物、制备方法及其应用
CN101195615B (zh) * 2006-12-06 2013-03-27 深圳市信立泰资产管理有限公司 咪唑-5-羧酸衍生物的盐、制备方法及其药物组合物
CA2671816C (en) * 2006-12-06 2012-06-05 Shanghai Allist Pharmaceutical., Inc. Salts of imidazole-5-carboxylic acid derivatives, a method for preparing same and pharmaceutical compositions comprising same
CN101214242A (zh) * 2007-01-05 2008-07-09 上海艾力斯医药科技有限公司 新的药用组合物
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
AU2008261102B2 (en) 2007-06-04 2013-11-28 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CN101317842A (zh) 2007-06-07 2008-12-10 上海艾力斯医药科技有限公司 一种咪唑-5-羧酸衍生物的治疗用途
CN101367795B (zh) * 2007-08-17 2012-05-02 上海艾力斯生物医药有限公司 一种咪唑-5-羧酸衍生物及其制备方法
CN101407511B (zh) * 2007-10-11 2013-01-09 上海艾力斯生物医药有限公司 一种结晶型的咪唑-5-羧酸衍生物
EP2328910B1 (en) 2008-06-04 2014-08-06 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP3241839B1 (en) 2008-07-16 2019-09-04 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN103012377A (zh) * 2011-09-27 2013-04-03 江苏艾力斯生物医药有限公司 一种咪唑-5-羧酸酯的重结晶方法
WO2014151206A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
BR112015030326A2 (pt) 2013-06-05 2017-08-29 Synergy Pharmaceuticals Inc Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1334092C (en) * 1986-07-11 1995-01-24 David John Carini Angiotensin ii receptor blocking imidazoles
US5064825A (en) * 1989-06-01 1991-11-12 Merck & Co., Inc. Angiotensin ii antagonists
WO1991000281A2 (en) * 1989-06-30 1991-01-10 E.I. Du Pont De Nemours And Company Fused-ring aryl substituted imidazoles
EP0411507B1 (en) * 1989-08-02 1994-10-26 Takeda Chemical Industries, Ltd. Pyrazole derivatives, their production and use
DE4132631A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Imidazolyl-propensaeurederivate
DE4132632A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Substituierte imidazolyl-propensaeurederivate
DE69329982T2 (de) * 1992-06-02 2001-09-27 Sankyo Co., Ltd. 4-Carboxyimidazolderivate als Angiotensin-II-Antagonisten und ihre therapeutische Verwendung

Also Published As

Publication number Publication date
HUT62291A (en) 1993-04-28
AT398202B (de) 1994-10-25
YU48290B (sh) 1998-05-15
JPH05310731A (ja) 1993-11-22
RU2105764C1 (ru) 1998-02-27
HU9203149D0 (en) 1992-12-28
FI924353A0 (fi) 1992-09-29
HRP920817A2 (en) 1996-08-31
FI924353A (fi) 1993-04-05
ATA198791A (de) 1994-02-15
IL103329A0 (en) 1993-03-15
NO923798L (no) 1993-04-05
IL103329A (en) 1996-10-31
ZA927205B (en) 1993-03-23
CN1071426A (zh) 1993-04-28
YU87592A (sh) 1995-10-03
CZ301992A3 (en) 1993-08-11
NZ244320A (en) 1995-01-27
JP2544565B2 (ja) 1996-10-16
EP0535420A1 (de) 1993-04-07
TW223073B (sk) 1994-05-01
AU2617692A (en) 1993-04-08
LV10256B (en) 1995-04-20
MY108350A (en) 1996-09-30
NO923798D0 (no) 1992-09-30
LV10256A (lv) 1994-10-20
CN1032856C (zh) 1996-09-25
CA2079735A1 (en) 1993-04-05
SK301992A3 (en) 1995-10-11
US5298519A (en) 1994-03-29
AU649357B2 (en) 1994-05-19

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