SI2459702T1 - Gojišče celične kulture za izražanje adamts proteina - Google Patents

Gojišče celične kulture za izražanje adamts proteina

Info

Publication number: SI2459702T1
Authority: SI; Slovenia
Prior art keywords: culture medium; cell culture; protein expression; adamts protein; adamts
Prior art date: 2009-07-31

Application number

SI201031238A

Other languages

English (en)

Inventor

Leopold Grillberger

Alexandra Spenger

Meinhard Hasslacher

Rana Grillberger

Manfred Reiter

Original Assignee

Baxalta GmbH

Baxalta Incorporated

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-07-31

Filing date

2010-07-30

Publication date

2016-11-30

2010-07-30 Application filed by Baxalta GmbH, Baxalta Incorporated filed Critical Baxalta GmbH

2016-11-30 Publication of SI2459702T1 publication Critical patent/SI2459702T1/sl

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
- C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0684—Cells of the urinary tract or kidneys
- C12N5/0686—Kidney cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/24—Metalloendopeptidases (3.4.24)
- C12Y304/24087—ADAMTS13 endopeptidase (3.4.24.87)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
- C12N2500/14—Calcium; Ca chelators; Calcitonin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/22—Zinc; Zn chelators
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
- C12N2500/95—Protein-free medium and culture conditions
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/99—Serum-free medium
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Cell Biology (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Tropical Medicine & Parasitology (AREA)
Virology (AREA)

SI201031238A 2009-07-31 2010-07-30 Gojišče celične kulture za izražanje adamts proteina SI2459702T1 (sl)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US23047709P	2009-07-31	2009-07-31
EP10740810.6A EP2459702B1 (en)	2009-07-31	2010-07-30	Cell culture medium for adamts protein expression
PCT/US2010/044020 WO2011014838A1 (en)	2009-07-31	2010-07-30	Cell culture medium for adamts protein expression

Publications (1)

Publication Number	Publication Date
SI2459702T1 true SI2459702T1 (sl)	2016-11-30

Family

ID=42668009

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI201031238A SI2459702T1 (sl)	2009-07-31	2010-07-30	Gojišče celične kulture za izražanje adamts proteina

Country Status (22)

Country	Link
US (7)	US8313926B2 (sl)
EP (1)	EP2459702B1 (sl)
JP (5)	JP5451884B2 (sl)
KR (5)	KR101574056B1 (sl)
CN (2)	CN102549145B (sl)
AU (1)	AU2010278751B2 (sl)
BR (2)	BR122021005965B1 (sl)
CA (1)	CA2769361A1 (sl)
CO (1)	CO6501191A2 (sl)
EA (1)	EA023193B1 (sl)
ES (1)	ES2583258T3 (sl)
HK (1)	HK1171790A1 (sl)
HR (1)	HRP20160783T1 (sl)
HU (1)	HUE029110T2 (sl)
IN (1)	IN2012DN00801A (sl)
MX (2)	MX2012001261A (sl)
NZ (1)	NZ597727A (sl)
PL (1)	PL2459702T3 (sl)
PT (1)	PT2459702T (sl)
SG (1)	SG178194A1 (sl)
SI (1)	SI2459702T1 (sl)
WO (1)	WO2011014838A1 (sl)

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SG178194A1 (en) *	2009-07-31	2012-03-29	Baxter Int	Cell culture medium for adamts protein expression
ES2761692T5 (es)	2010-07-08	2023-07-05	Takeda Pharmaceuticals Co	Método de producción de vWF recombinante de alto peso molecular en cultivo celular
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WO2014062535A1 (en)	2012-10-15	2014-04-24	Bristol-Myers Squibb Company	Mammalian cell culture processes for protein production
WO2014159831A1 (en)	2013-03-13	2014-10-02	Merck Sharp & Dohme Corp.	Adapted lepidopteran insect cells for the production of recombinant proteins
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AR095196A1 (es)	2013-03-15	2015-09-30	Regeneron Pharma	Medio de cultivo celular libre de suero
KR102418824B1 (ko) *	2013-10-14	2022-07-11	아레스 트레이딩 에스.아.	포유동물의 고성능 유가식 배양을 위한 신규 배지
KR102391259B1 (ko)	2014-06-04	2022-04-26	암젠 인크	포유류 세포 배양물을 회수하는 방법
KR101867134B1 (ko) *	2015-03-23	2018-06-12	한양대학교 산학협력단	포유류 세포를 이용하여 목적 물질을 고효율로 생산하기 위한 세포 배양 배지, 이를 이용한 세포 배양 방법 및 목적 물질의 생산 방법
BR112017024579A2 (pt) *	2015-05-22	2018-07-31	Dupont Nutrition Biosci Aps	acetolactato descarboxilase
TW202340452A (zh)	2015-08-04	2023-10-16	美商再生元醫藥公司	補充牛磺酸之細胞培養基及用法
CN116159130A (zh)	2016-08-04	2023-05-26	武田药品工业株式会社	使用adamts13治疗、改善和/或预防镰状细胞病、急性肺损伤和/或急性呼吸窘迫综合征中的血管阻塞危象
ES2948849T3 (es) *	2016-11-04	2023-09-20	Takeda Pharmaceuticals Co	Métodos de purificación de virus adenoasociado
SG11202009047TA (en) *	2018-03-16	2020-10-29	Genzyme Corp	Methods for improving cell viability in a production bioreactor
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MY190626A (en)	2019-12-06	2022-04-27	Regeneron Pharma	Anti-vegf protein compositions and methods for producing the same
WO2021198781A2 (en)	2020-04-02	2021-10-07	Takeda Pharmaceutical Company Limited	Adamts13 variant, compositions, and uses thereof
CN115835904A (zh)	2020-05-22	2023-03-21	武田药品工业有限公司	用于治疗和诊断冠状病毒疾病并发症的adamts13组合物和方法
CN111808822B (zh) *	2020-07-02	2024-01-12	北京百普赛斯生物科技股份有限公司	细胞培养用补料液及提高重组hek293细胞蛋白表达量的方法

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SG178194A1 (en) *	2009-07-31	2012-03-29	Baxter Int	Cell culture medium for adamts protein expression

2010
- 2010-07-30 SG SG2012006839A patent/SG178194A1/en unknown
- 2010-07-30 SI SI201031238A patent/SI2459702T1/sl unknown
- 2010-07-30 HU HUE10740810A patent/HUE029110T2/en unknown
- 2010-07-30 AU AU2010278751A patent/AU2010278751B2/en active Active
- 2010-07-30 US US12/847,999 patent/US8313926B2/en active Active
- 2010-07-30 JP JP2012523110A patent/JP5451884B2/ja active Active
- 2010-07-30 EA EA201270224A patent/EA023193B1/ru not_active IP Right Cessation
- 2010-07-30 KR KR1020157009715A patent/KR101574056B1/ko active IP Right Grant
- 2010-07-30 KR KR1020177018298A patent/KR101808496B1/ko active IP Right Grant
- 2010-07-30 WO PCT/US2010/044020 patent/WO2011014838A1/en active Application Filing
- 2010-07-30 CN CN201080042028.1A patent/CN102549145B/zh active Active
- 2010-07-30 KR KR1020157033595A patent/KR101756354B1/ko active IP Right Grant
- 2010-07-30 PL PL10740810.6T patent/PL2459702T3/pl unknown
- 2010-07-30 MX MX2012001261A patent/MX2012001261A/es active IP Right Grant
- 2010-07-30 BR BR122021005965-9A patent/BR122021005965B1/pt active IP Right Grant
- 2010-07-30 EP EP10740810.6A patent/EP2459702B1/en active Active
- 2010-07-30 IN IN801DEN2012 patent/IN2012DN00801A/en unknown
- 2010-07-30 PT PT107408106T patent/PT2459702T/pt unknown
- 2010-07-30 CN CN201510186244.8A patent/CN104962539B/zh active Active
- 2010-07-30 KR KR1020177035177A patent/KR101912552B1/ko active IP Right Grant
- 2010-07-30 BR BR112012002151-6A patent/BR112012002151B1/pt active IP Right Grant
- 2010-07-30 KR KR1020127005425A patent/KR101573972B1/ko active IP Right Grant
- 2010-07-30 ES ES10740810.6T patent/ES2583258T3/es active Active
- 2010-07-30 NZ NZ597727A patent/NZ597727A/xx unknown
- 2010-07-30 CA CA2769361A patent/CA2769361A1/en not_active Abandoned
2012
- 2012-01-27 MX MX2013009470A patent/MX344970B/es unknown
- 2012-02-27 CO CO12033821A patent/CO6501191A2/es unknown
- 2012-09-19 US US13/622,939 patent/US8759026B2/en active Active
- 2012-12-06 HK HK12112610.1A patent/HK1171790A1/zh unknown
2014
- 2014-05-13 US US14/276,819 patent/US9127265B2/en active Active
2015
- 2015-07-23 US US14/807,745 patent/US9441216B2/en active Active
2016
- 2016-05-06 JP JP2016093240A patent/JP6511007B2/ja active Active
- 2016-07-04 HR HRP20160783TT patent/HRP20160783T1/hr unknown
- 2016-08-09 US US15/232,626 patent/US10072254B2/en active Active
2018
- 2018-01-26 JP JP2018011373A patent/JP6567707B2/ja active Active
- 2018-09-08 US US16/125,688 patent/US10724024B2/en active Active
2019
- 2019-07-31 JP JP2019141485A patent/JP6883071B2/ja active Active
2020
- 2020-06-16 US US16/903,185 patent/US11254921B2/en active Active
2021
- 2021-05-07 JP JP2021079239A patent/JP7083059B2/ja active Active

Also Published As

Publication number	Publication date
JP6511007B2 (ja)	2019-05-08
KR101573972B1 (ko)	2015-12-02
EP2459702B1 (en)	2016-05-04
JP6883071B2 (ja)	2021-06-09
KR101756354B1 (ko)	2017-07-26
HUE029110T2 (en)	2017-02-28
CN104962539A (zh)	2015-10-07
HRP20160783T1 (hr)	2016-08-12
SG178194A1 (en)	2012-03-29
US8313926B2 (en)	2012-11-20
JP7083059B2 (ja)	2022-06-09
BR112012002151A2 (pt)	2020-03-03
KR101912552B1 (ko)	2018-10-26
US20140329294A1 (en)	2014-11-06
US10724024B2 (en)	2020-07-28
US11254921B2 (en)	2022-02-22
HK1171790A1 (zh)	2013-04-05
US9441216B2 (en)	2016-09-13
CA2769361A1 (en)	2011-02-03
IN2012DN00801A (sl)	2015-06-26
JP2019201661A (ja)	2019-11-28
US10072254B2 (en)	2018-09-11
WO2011014838A1 (en)	2011-02-03
JP2021112210A (ja)	2021-08-05
KR20170081747A (ko)	2017-07-12
CO6501191A2 (es)	2012-08-15
US20170051270A1 (en)	2017-02-23
KR101808496B1 (ko)	2017-12-12
US20130071906A1 (en)	2013-03-21
AU2010278751A1 (en)	2012-02-09
BR112012002151B1 (pt)	2021-07-06
MX2012001261A (es)	2012-05-22
CN102549145A (zh)	2012-07-04
PT2459702T (pt)	2016-08-02
US20190071660A1 (en)	2019-03-07
KR20120046301A (ko)	2012-05-09
JP5451884B2 (ja)	2014-03-26
EA023193B1 (ru)	2016-05-31
MX344970B (es)	2017-01-12
JP2013500724A (ja)	2013-01-10
EA201270224A1 (ru)	2012-09-28
KR20170140411A (ko)	2017-12-20
EP2459702A1 (en)	2012-06-06
JP2014061005A (ja)	2014-04-10
PL2459702T3 (pl)	2016-12-30
CN102549145B (zh)	2015-05-20
JP5936232B2 (ja)	2016-06-22
JP2016144471A (ja)	2016-08-12
US20150329848A1 (en)	2015-11-19
BR122021005965B1 (pt)	2022-01-25
JP6567707B2 (ja)	2019-08-28
US8759026B2 (en)	2014-06-24
KR20150138425A (ko)	2015-12-09
KR101574056B1 (ko)	2015-12-02
US20110086413A1 (en)	2011-04-14
NZ597727A (en)	2013-08-30
AU2010278751B2 (en)	2014-05-15
KR20150044981A (ko)	2015-04-27
ES2583258T3 (es)	2016-09-20
US20200308566A1 (en)	2020-10-01
CN104962539B (zh)	2019-09-17
JP2018093881A (ja)	2018-06-21
US9127265B2 (en)	2015-09-08

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