AR095196A1 - Medio de cultivo celular libre de suero - Google Patents

Medio de cultivo celular libre de suero

Info

Publication number
AR095196A1
AR095196A1 ARP140100803A ARP140100803A AR095196A1 AR 095196 A1 AR095196 A1 AR 095196A1 AR P140100803 A ARP140100803 A AR P140100803A AR P140100803 A ARP140100803 A AR P140100803A AR 095196 A1 AR095196 A1 AR 095196A1
Authority
AR
Argentina
Prior art keywords
serum free
free cell
cell cultivation
cultivation media
ornithine
Prior art date
Application number
ARP140100803A
Other languages
English (en)
Original Assignee
Regeneron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51528781&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR095196(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of AR095196A1 publication Critical patent/AR095196A1/es

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C—CHEMISTRY; METALLURGY
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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0031—Serum-free culture media
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0037—Serum-free medium, which may still contain naturally-sourced components
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0043—Medium free of human- or animal-derived components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/005—Protein-free medium
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
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    • C12N2500/05—Inorganic components
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    • C12N2500/24—Iron; Fe chelators; Transferrin
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    • C12N2500/00—Specific components of cell culture medium
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    • C12N2500/32—Amino acids
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/34—Sugars
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/46—Amines, e.g. putrescine
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    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production
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    • C12N2523/00—Culture process characterised by temperature

Abstract

La memoria descriptiva describe un medio de cultivo celular mejorado libre de suero animal, que puede usarse para la producción de una proteína de interés. La ornitina, o una combinación de ornitina y putrescina puede agregarse a medios libres de suero o medios definidos en forma química para mejorar la densidad de células viables, para reducir el tiempo de duplicación celular, y para aumentar la producción de una proteína de interés.
ARP140100803A 2013-03-15 2014-03-10 Medio de cultivo celular libre de suero AR095196A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361790136P 2013-03-15 2013-03-15

Publications (1)

Publication Number Publication Date
AR095196A1 true AR095196A1 (es) 2015-09-30

Family

ID=51528781

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP140100803A AR095196A1 (es) 2013-03-15 2014-03-10 Medio de cultivo celular libre de suero

Country Status (22)

Country Link
US (4) US20140273095A1 (es)
EP (4) EP4159841A1 (es)
JP (5) JP6781039B2 (es)
KR (5) KR102278316B1 (es)
CN (2) CN113481148A (es)
AR (1) AR095196A1 (es)
AU (4) AU2014227804B2 (es)
BR (2) BR122020021864B1 (es)
CA (3) CA2906768C (es)
DK (1) DK2970876T3 (es)
EA (3) EA202190326A3 (es)
ES (1) ES2682929T3 (es)
HK (1) HK1213289A1 (es)
HU (1) HUE040233T2 (es)
IL (5) IL281515B1 (es)
MX (3) MX357977B (es)
MY (1) MY175957A (es)
PL (1) PL2970876T3 (es)
PT (1) PT2970876T (es)
SG (3) SG11201507072TA (es)
TW (4) TWI629359B (es)
WO (1) WO2014144198A1 (es)

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