SI2018380T1 - CNS-aktivirani kondenzirani biciklično in heterociklično substituirani azabiciklični derivati alkanov - Google Patents

CNS-aktivirani kondenzirani biciklično in heterociklično substituirani azabiciklični derivati alkanov

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Publication number
SI2018380T1
SI2018380T1 SI200730810T SI200730810T SI2018380T1 SI 2018380 T1 SI2018380 T1 SI 2018380T1 SI 200730810 T SI200730810 T SI 200730810T SI 200730810 T SI200730810 T SI 200730810T SI 2018380 T1 SI2018380 T1 SI 2018380T1
Authority
SI
Slovenia
Prior art keywords
alkane derivatives
cns active
substituted azabicyclic
fused bicycloheterocycle
azabicyclic alkane
Prior art date
Application number
SI200730810T
Other languages
English (en)
Inventor
Jianguo Ji
Tao Li
Christopher L Lynch
Murali Gopalakrishnan
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of SI2018380T1 publication Critical patent/SI2018380T1/sl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/08—Diarylmethoxy radicals
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SI200730810T 2006-05-19 2007-05-15 CNS-aktivirani kondenzirani biciklično in heterociklično substituirani azabiciklični derivati alkanov SI2018380T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80219506P 2006-05-19 2006-05-19
EP07797473A EP2018380B1 (en) 2006-05-19 2007-05-15 Cns active fused bicycloheterocycle substituted azabicyclic alkane derivatives
PCT/US2007/068930 WO2007137030A2 (en) 2006-05-19 2007-05-15 Cns active fused bicycloheterocycle substituted azabicyclic alkane derivatives

Publications (1)

Publication Number Publication Date
SI2018380T1 true SI2018380T1 (sl) 2012-02-29

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SI200730810T SI2018380T1 (sl) 2006-05-19 2007-05-15 CNS-aktivirani kondenzirani biciklično in heterociklično substituirani azabiciklični derivati alkanov

Country Status (30)

Country Link
US (2) US7872017B2 (sl)
EP (2) EP2018380B1 (sl)
JP (3) JP5420398B2 (sl)
KR (1) KR20090018972A (sl)
CN (2) CN102516241B (sl)
AT (1) ATE529423T1 (sl)
AU (1) AU2007253950B2 (sl)
BR (1) BRPI0711588A2 (sl)
CA (1) CA2647830C (sl)
CY (1) CY1112531T1 (sl)
DK (1) DK2018380T3 (sl)
EC (1) ECSP088918A (sl)
ES (2) ES2373792T3 (sl)
GT (1) GT200800248A (sl)
HK (1) HK1122569A1 (sl)
HR (1) HRP20110917T1 (sl)
IL (1) IL195234A0 (sl)
MX (1) MX2008014672A (sl)
MY (1) MY147661A (sl)
NO (1) NO20085153L (sl)
NZ (2) NZ589784A (sl)
PL (1) PL2018380T3 (sl)
PT (1) PT2018380E (sl)
RS (1) RS52062B (sl)
RU (2) RU2437884C2 (sl)
SI (1) SI2018380T1 (sl)
TW (1) TWI343385B (sl)
UA (1) UA92083C2 (sl)
WO (1) WO2007137030A2 (sl)
ZA (2) ZA200810687B (sl)

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