US4419446A
(en)
|
1980-12-31 |
1983-12-06 |
The United States Of America As Represented By The Department Of Health And Human Services |
Recombinant DNA process utilizing a papilloma virus DNA as a vector
|
US4601978A
(en)
|
1982-11-24 |
1986-07-22 |
The Regents Of The University Of California |
Mammalian metallothionein promoter system
|
US4560655A
(en)
|
1982-12-16 |
1985-12-24 |
Immunex Corporation |
Serum-free cell culture medium and process for making same
|
US4657866A
(en)
|
1982-12-21 |
1987-04-14 |
Sudhir Kumar |
Serum-free, synthetic, completely chemically defined tissue culture media
|
US4767704A
(en)
|
1983-10-07 |
1988-08-30 |
Columbia University In The City Of New York |
Protein-free culture medium
|
US4965199A
(en)
|
1984-04-20 |
1990-10-23 |
Genentech, Inc. |
Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
|
GB8516415D0
(en)
|
1985-06-28 |
1985-07-31 |
Celltech Ltd |
Culture of animal cells
|
US4676980A
(en)
|
1985-09-23 |
1987-06-30 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Target specific cross-linked heteroantibodies
|
GB8601597D0
(en)
|
1986-01-23 |
1986-02-26 |
Wilson R H |
Nucleotide sequences
|
US4927762A
(en)
|
1986-04-01 |
1990-05-22 |
Cell Enterprises, Inc. |
Cell culture medium with antioxidant
|
EP0307434B2
(fr)
|
1987-03-18 |
1998-07-29 |
Scotgen Biopharmaceuticals, Inc. |
Anticorps alteres
|
US5770701A
(en)
|
1987-10-30 |
1998-06-23 |
American Cyanamid Company |
Process for preparing targeted forms of methyltrithio antitumor agents
|
US5606040A
(en)
|
1987-10-30 |
1997-02-25 |
American Cyanamid Company |
Antitumor and antibacterial substituted disulfide derivatives prepared from compounds possessing a methyl-trithio group
|
DE68925971T2
(de)
|
1988-09-23 |
1996-09-05 |
Cetus Oncology Corp |
Zellenzuchtmedium für erhöhtes zellenwachstum, zur erhöhung der langlebigkeit und expression der produkte
|
KR0184860B1
(ko)
|
1988-11-11 |
1999-04-01 |
메디칼 리써어치 카운실 |
단일영역 리간드와 이를 포함하는 수용체 및 이들의 제조방법과 이용(법)
|
US5089261A
(en)
|
1989-01-23 |
1992-02-18 |
Cetus Corporation |
Preparation of a polymer/interleukin-2 conjugate
|
SE509359C2
(sv)
|
1989-08-01 |
1999-01-18 |
Cemu Bioteknik Ab |
Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel
|
US5208020A
(en)
|
1989-10-25 |
1993-05-04 |
Immunogen Inc. |
Cytotoxic agents comprising maytansinoids and their therapeutic use
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
US6075181A
(en)
|
1990-01-12 |
2000-06-13 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
DE69120146T2
(de)
|
1990-01-12 |
1996-12-12 |
Cell Genesys Inc |
Erzeugung xenogener antikörper
|
US6150584A
(en)
|
1990-01-12 |
2000-11-21 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
US5891693A
(en)
|
1990-01-25 |
1999-04-06 |
Alusuisse Holdings A.G. |
Recombinant DNA methods vectors and host cells
|
EP0547163B1
(fr)
|
1990-08-29 |
2002-02-06 |
Centre Hospitalier Regional De Nantes |
Polyligands de proteine joints a un noyau de proteine stable
|
US5122469A
(en)
|
1990-10-03 |
1992-06-16 |
Genentech, Inc. |
Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins
|
US5508192A
(en)
|
1990-11-09 |
1996-04-16 |
Board Of Regents, The University Of Texas System |
Bacterial host strains for producing proteolytically sensitive polypeptides
|
US5264365A
(en)
|
1990-11-09 |
1993-11-23 |
Board Of Regents, The University Of Texas System |
Protease-deficient bacterial strains for production of proteolytically sensitive polypeptides
|
US5650150A
(en)
|
1990-11-09 |
1997-07-22 |
Gillies; Stephen D. |
Recombinant antibody cytokine fusion proteins
|
US5571894A
(en)
|
1991-02-05 |
1996-11-05 |
Ciba-Geigy Corporation |
Recombinant antibodies specific for a growth factor receptor
|
US7018809B1
(en)
|
1991-09-19 |
2006-03-28 |
Genentech, Inc. |
Expression of functional antibody fragments
|
US5587458A
(en)
|
1991-10-07 |
1996-12-24 |
Aronex Pharmaceuticals, Inc. |
Anti-erbB-2 antibodies, combinations thereof, and therapeutic and diagnostic uses thereof
|
WO1993008829A1
(fr)
|
1991-11-04 |
1993-05-13 |
The Regents Of The University Of California |
Compositions induisant la destruction de cellules infectees par l'hiv
|
US5288931A
(en)
*
|
1991-12-06 |
1994-02-22 |
Genentech, Inc. |
Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
|
AU675929B2
(en)
|
1992-02-06 |
1997-02-27 |
Curis, Inc. |
Biosynthetic binding protein for cancer marker
|
WO1993022332A2
(fr)
|
1992-04-24 |
1993-11-11 |
Board Of Regents, The University Of Texas System |
Production recombinante de domaines semblables a l'immunoglobuline dans des cellules procaryotes
|
CA2149329C
(fr)
|
1992-11-13 |
2008-07-15 |
Darrell R. Anderson |
Utilisation d'anticorps hybrides et radioisotopiques diriges contre l'antigene de restriction de la differenciation des lymphocytes b humains pour le traitement du lymphome b
|
US5635483A
(en)
|
1992-12-03 |
1997-06-03 |
Arizona Board Of Regents Acting On Behalf Of Arizona State University |
Tumor inhibiting tetrapeptide bearing modified phenethyl amides
|
US5780588A
(en)
|
1993-01-26 |
1998-07-14 |
Arizona Board Of Regents |
Elucidation and synthesis of selected pentapeptides
|
JPH08511420A
(ja)
|
1993-06-16 |
1996-12-03 |
セルテック・セラピューテイクス・リミテッド |
抗 体
|
US5773001A
(en)
|
1994-06-03 |
1998-06-30 |
American Cyanamid Company |
Conjugates of methyltrithio antitumor agents and intermediates for their synthesis
|
US5639635A
(en)
|
1994-11-03 |
1997-06-17 |
Genentech, Inc. |
Process for bacterial production of polypeptides
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
US5641870A
(en)
|
1995-04-20 |
1997-06-24 |
Genentech, Inc. |
Low pH hydrophobic interaction chromatography for antibody purification
|
US5869046A
(en)
|
1995-04-14 |
1999-02-09 |
Genentech, Inc. |
Altered polypeptides with increased half-life
|
US5739277A
(en)
|
1995-04-14 |
1998-04-14 |
Genentech Inc. |
Altered polypeptides with increased half-life
|
US5714586A
(en)
|
1995-06-07 |
1998-02-03 |
American Cyanamid Company |
Methods for the preparation of monomeric calicheamicin derivative/carrier conjugates
|
US5712374A
(en)
|
1995-06-07 |
1998-01-27 |
American Cyanamid Company |
Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates
|
GB9603256D0
(en)
|
1996-02-16 |
1996-04-17 |
Wellcome Found |
Antibodies
|
AU2660397A
(en)
|
1996-04-05 |
1997-10-29 |
Board Of Regents, The University Of Texas System |
Methods for producing soluble, biologically-active disulfide bond-containing eukaryotic proteins in bacterial cells
|
US5834597A
(en)
|
1996-05-20 |
1998-11-10 |
Protein Design Labs, Inc. |
Mutated nonactivating IgG2 domains and anti CD3 antibodies incorporating the same
|
DE19701141C1
(de)
|
1997-01-16 |
1998-04-09 |
Hoechst Ag |
Genkonstrukte für durch Proteasen aktivierbare Wirksubstanzen
|
US6277375B1
(en)
|
1997-03-03 |
2001-08-21 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
US6083715A
(en)
|
1997-06-09 |
2000-07-04 |
Board Of Regents, The University Of Texas System |
Methods for producing heterologous disulfide bond-containing polypeptides in bacterial cells
|
DE69830315T2
(de)
|
1997-06-24 |
2006-02-02 |
Genentech Inc., San Francisco |
Galactosylierte glykoproteine enthaltende zusammensetzungen und verfahren zur deren herstellung
|
ATE419009T1
(de)
|
1997-10-31 |
2009-01-15 |
Genentech Inc |
Methoden und zusammensetzungen bestehend aus glykoprotein-glykoformen
|
ATE375365T1
(de)
|
1998-04-02 |
2007-10-15 |
Genentech Inc |
Antikörper varianten und fragmente davon
|
AU3657899A
(en)
|
1998-04-20 |
1999-11-08 |
James E. Bailey |
Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity
|
EP2275540B1
(fr)
|
1999-04-09 |
2016-03-23 |
Kyowa Hakko Kirin Co., Ltd. |
Procédé de contrôle de l'activité de molécule fonctionnelle immunologique
|
GB9912350D0
(en)
*
|
1999-05-26 |
1999-07-28 |
European Molecular Biology Lab Embl |
Modified cytokine
|
IT1306736B1
(it)
|
1999-10-29 |
2001-10-02 |
Benito Salmi |
Dispositivo di contenimento e distribuzione di palloni per tiri alvolo.
|
AU767394C
(en)
|
1999-12-29 |
2005-04-21 |
Immunogen, Inc. |
Cytotoxic agents comprising modified doxorubicins and daunorubicins and their therapeutic use
|
EP1276849A4
(fr)
|
2000-04-12 |
2004-06-09 |
Human Genome Sciences Inc |
Proteines fusionnees a de l'albumine
|
US20040014652A1
(en)
|
2000-06-01 |
2004-01-22 |
Andre Trouet |
Tumor activated prodrug compounds and methods of making and using the same
|
DE10045592A1
(de)
|
2000-09-15 |
2002-03-28 |
Klaus Pfizenmaier |
Ein Antikörper-TNF-TNF Inhibitor Fusionsprotein (TNF-Selektokin) als zielspezifisches Prozytokin zur Tumortherapie
|
US7064191B2
(en)
|
2000-10-06 |
2006-06-20 |
Kyowa Hakko Kogyo Co., Ltd. |
Process for purifying antibody
|
JP3523245B1
(ja)
|
2000-11-30 |
2004-04-26 |
メダレックス,インコーポレーテッド |
ヒト抗体作製用トランスジェニック染色体導入齧歯動物
|
EP2341060B1
(fr)
|
2000-12-12 |
2019-02-20 |
MedImmune, LLC |
Molecules a demi-vies longues, compositions et utilisations de celles-ci
|
US6942853B2
(en)
|
2001-01-09 |
2005-09-13 |
Queen Mary And Westfield College |
Latent fusion protein
|
CA2440582A1
(fr)
|
2001-03-09 |
2002-10-03 |
Dyax Corp. |
Groupes de liaison d'albumine serique
|
FI117667B
(fi)
*
|
2001-07-05 |
2007-01-15 |
Univ Zuerich |
Farmaseuttinen koostumus, joka soveltuu käytettäväksi ortopediassa ja hammaslääketieteessä
|
NZ592087A
(en)
|
2001-08-03 |
2012-11-30 |
Roche Glycart Ag |
Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
|
AU2002355955A1
(en)
|
2001-08-13 |
2003-03-03 |
University Of Southern California |
Interleukin-2 mutants with reduced toxicity
|
ES2326964T3
(es)
|
2001-10-25 |
2009-10-22 |
Genentech, Inc. |
Composiciones de glicoproteina.
|
EP2277889B1
(fr)
|
2001-12-21 |
2014-07-09 |
Human Genome Sciences, Inc. |
Protéines chimériques d'albumine et interféron beta
|
EP1463752A4
(fr)
|
2001-12-21 |
2005-07-13 |
Human Genome Sciences Inc |
Proteines de fusion d'albumine
|
US20040093621A1
(en)
|
2001-12-25 |
2004-05-13 |
Kyowa Hakko Kogyo Co., Ltd |
Antibody composition which specifically binds to CD20
|
US7691568B2
(en)
|
2002-04-09 |
2010-04-06 |
Kyowa Hakko Kirin Co., Ltd |
Antibody composition-containing medicament
|
AU2003236018A1
(en)
|
2002-04-09 |
2003-10-20 |
Kyowa Hakko Kirin Co., Ltd. |
METHOD OF ENHANCING ACTIVITY OF ANTIBODY COMPOSITION OF BINDING TO FcGamma RECEPTOR IIIa
|
AU2003236019A1
(en)
|
2002-04-09 |
2003-10-20 |
Kyowa Hakko Kirin Co., Ltd. |
Drug containing antibody composition appropriate for patient suffering from Fc Gamma RIIIa polymorphism
|
ATE503829T1
(de)
|
2002-04-09 |
2011-04-15 |
Kyowa Hakko Kirin Co Ltd |
Zelle mit erniedrigter oder deletierter aktivität eines am gdp-fucosetransport beteiligten proteins
|
CA2481837A1
(fr)
|
2002-04-09 |
2003-10-16 |
Kyowa Hakko Kogyo Co., Ltd. |
Procede de production de composition anticorps
|
ES2425013T3
(es)
*
|
2002-06-12 |
2013-10-10 |
Symphony Evolution, Inc. |
Inhibidores de ADAM-10 humana
|
AU2003265866A1
(en)
|
2002-09-03 |
2004-03-29 |
Vit Lauermann |
Targeted release
|
CN1703423A
(zh)
|
2002-10-14 |
2005-11-30 |
豪夫迈-罗氏公司 |
Il-15拮抗剂
|
US7361740B2
(en)
|
2002-10-15 |
2008-04-22 |
Pdl Biopharma, Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
JP2006524036A
(ja)
|
2002-11-08 |
2006-10-26 |
アブリンクス エン.ヴェー. |
腫瘍壊死因子αを標的とする単一ドメイン抗体およびその使用
|
DE60332957D1
(de)
|
2002-12-16 |
2010-07-22 |
Genentech Inc |
Immunoglobulinvarianten und deren verwendungen
|
TWI364295B
(en)
|
2002-12-26 |
2012-05-21 |
Mountain View Pharmaceuticals |
Polymer conjugates of cytokines, chemokines, growth factors, polypeptide hormones and antagonists thereof with preserved receptor-binding activity
|
WO2004090135A2
(fr)
|
2003-04-09 |
2004-10-21 |
Asterion Limited |
Polypeptides contenant du glycosylphosphatidylinositol
|
US20080241884A1
(en)
|
2003-10-08 |
2008-10-02 |
Kenya Shitara |
Fused Protein Composition
|
AU2004280065A1
(en)
|
2003-10-09 |
2005-04-21 |
Kyowa Hakko Kirin Co., Ltd. |
Process for producing antibody composition by using RNA inhibiting the function of alpha1,6-fucosyltransferase
|
KR101520209B1
(ko)
|
2003-11-06 |
2015-05-13 |
시애틀 지네틱스, 인크. |
리간드에 접합될 수 있는 모노메틸발린 화합물
|
JPWO2005053742A1
(ja)
|
2003-12-04 |
2007-06-28 |
協和醗酵工業株式会社 |
抗体組成物を含有する医薬
|
BRPI0507026A
(pt)
|
2004-02-09 |
2007-04-17 |
Human Genome Sciences Inc |
proteìnas de fusão de albumina
|
AU2004101073B4
(en)
|
2004-12-21 |
2005-08-18 |
Kerry William O'Hanlon |
A Beverage Container Holder
|
US10011858B2
(en)
|
2005-03-31 |
2018-07-03 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for producing polypeptides by regulating polypeptide association
|
WO2006110728A2
(fr)
|
2005-04-12 |
2006-10-19 |
The Uab Research Foundation |
Agregats de tegument immunogenes
|
US20070269422A1
(en)
|
2006-05-17 |
2007-11-22 |
Ablynx N.V. |
Serum albumin binding proteins with long half-lives
|
AU2007258609B2
(en)
|
2006-06-07 |
2013-01-24 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
US7939632B2
(en)
*
|
2006-06-14 |
2011-05-10 |
Csl Behring Gmbh |
Proteolytically cleavable fusion proteins with high molar specific activity
|
EP1867660A1
(fr)
|
2006-06-14 |
2007-12-19 |
CSL Behring GmbH |
Protéine de fusion qui peut être clivée protéolyticalement et qui contient un facteur de la coagulation sanguine
|
US20110252501A1
(en)
*
|
2006-08-17 |
2011-10-13 |
Monsanto Technology Llc |
Transgenic plants with enhanced agronomic traits
|
EP2068905A4
(fr)
|
2006-09-14 |
2009-12-30 |
Human Genome Sciences Inc |
Protéines de fusion d'albumine
|
ATE554859T1
(de)
|
2007-05-24 |
2012-05-15 |
Univ California |
Integrierte fluidische vorrichtungen mit magnetischer sortierung
|
US20090304719A1
(en)
|
2007-08-22 |
2009-12-10 |
Patrick Daugherty |
Activatable binding polypeptides and methods of identification and use thereof
|
JP2011512134A
(ja)
|
2008-02-19 |
2011-04-21 |
アステリオン・リミテッド |
修飾リンカー
|
US8575102B2
(en)
|
2008-08-01 |
2013-11-05 |
Nektar Therapeutics |
Conjugates having a releasable linkage
|
GB0815216D0
(en)
|
2008-08-21 |
2008-09-24 |
Asterion Ltd |
Interleukin
|
RU2636046C2
(ru)
|
2009-01-12 |
2017-11-17 |
Сайтомкс Терапьютикс, Инк |
Композиции модифицированных антител, способы их получения и применения
|
BRPI1011384A2
(pt)
|
2009-02-23 |
2016-03-15 |
Cytomx Therapeutics Inc |
pro-proteinas e seus metodos de uso
|
EP2456787A4
(fr)
|
2009-07-24 |
2013-01-30 |
Univ Leland Stanford Junior |
Compositions de cytokine et leurs méthodes d utilisation
|
US20130064788A1
(en)
|
2009-10-10 |
2013-03-14 |
Eleven Biotherapeutics, Inc. |
Il-17 family cytokine compositions and uses
|
US8734774B2
(en)
*
|
2010-04-02 |
2014-05-27 |
University Of Rochester |
Protease activated cytokines
|
CN106977608A
(zh)
|
2010-04-09 |
2017-07-25 |
阿尔布麦狄克斯公司 |
白蛋白衍生物和变体
|
WO2012054929A2
(fr)
|
2010-10-22 |
2012-04-26 |
Protox Therapeutics Corp. |
Utilisation d'albumine sérique humaine pour diminuer l'immunogénicité de protéines thérapeutiques
|
WO2012059486A1
(fr)
|
2010-11-01 |
2012-05-10 |
Novozymes Biopharma Dk A/S |
Variants d'albumine
|
LT2637694T
(lt)
|
2010-11-12 |
2021-05-25 |
Nektar Therapeutics |
Il-2 fragmento konjugatai ir polimeras
|
CU23923B1
(es)
|
2010-11-12 |
2013-07-31 |
Ct De Inmunología Molecular |
Polipéptidos derivados de la il-2 con actividad agonista
|
WO2012106615A1
(fr)
*
|
2011-02-03 |
2012-08-09 |
Xoma Technology Ltd. |
Procédés et matériaux pour améliorer l'expression d'une protéine fonctionnelle dans des bactéries
|
WO2013163631A2
(fr)
|
2012-04-27 |
2013-10-31 |
Cytomx Therapeutics, Inc. |
Anticorps activables liant le récepteur du facteur de croissance épidermique et leurs procédés d'utilisation
|
AU2013278075B2
(en)
|
2012-06-22 |
2018-05-17 |
Cytomx Therapeutics, Inc. |
Anti-jagged 1/Jagged 2 cross-reactive antibodies, activatable anti-Jagged antibodies and methods of use thereof
|
WO2013192546A1
(fr)
|
2012-06-22 |
2013-12-27 |
Cytomx Therapeutics, Inc. |
Anticorps activables ayant des fragments stériques ne se liant pas et leurs procédés d'utilisation
|
IN2015KN00329A
(fr)
|
2012-08-09 |
2015-07-10 |
Univ Leland Stanford Junior |
|
EP2882844B1
(fr)
|
2012-08-10 |
2018-10-03 |
Cytomx Therapeutics Inc. |
Systèmes résistant aux protéases pour présentation de polypeptides, leurs procédés de préparation et utilisation
|
WO2014052462A2
(fr)
|
2012-09-25 |
2014-04-03 |
Cytomx Therapeutics, Inc. |
Anticorps activables qui se lient au récepteur d'interleukine-6 et procédés d'utilisation de ces derniers
|
WO2014100014A1
(fr)
|
2012-12-17 |
2014-06-26 |
The Board Of Trustees Of The Leland Stanford Junior University |
Super-complexes 2 avec anticorps pour une amélioration de la thérapie par il-2
|
JP6605957B2
(ja)
|
2013-01-04 |
2019-11-13 |
シトムクス セラピューティクス,インコーポレイティド |
生体系におけるプロテアーゼ活性を検出するための組成物及び方法
|
WO2014120555A1
(fr)
|
2013-01-31 |
2014-08-07 |
The Regents Of The University Of California |
Anticorps spécifiques pour l'activateur de plasminogène de type urokinase et procédés d'utilisation de ceux-ci
|
WO2014165093A2
(fr)
|
2013-03-13 |
2014-10-09 |
Bristol-Myers Squibb Company |
Domaines d'échafaudage à base de fibronectine liés à une sérum albumine ou fragment se liant à celle-ci
|
US9517276B2
(en)
|
2013-06-04 |
2016-12-13 |
Cytomx Therapeutics, Inc. |
Compositions and methods for conjugating activatable antibodies
|
HRP20220553T1
(hr)
|
2013-07-25 |
2022-06-10 |
Cytomx Therapeutics Inc. |
Polispecifična protutijela, polispecifična protutijela koja se mogu aktivirati i postupci uporabe navedenih protutijela
|
CA3214529A1
(fr)
|
2013-09-25 |
2015-04-02 |
Cytomx Therapeutics, Inc. |
Substrats pour metalloproteinases matricielles et autres fragments clivables et leurs procedes d'utilisation
|
US9540440B2
(en)
|
2013-10-30 |
2017-01-10 |
Cytomx Therapeutics, Inc. |
Activatable antibodies that bind epidermal growth factor receptor and methods of use thereof
|
WO2015089283A1
(fr)
|
2013-12-11 |
2015-06-18 |
Cytomx Therapeutics, Inc. |
Anticorps qui se lient à des anticorps activables et leurs procédés d'utilisation
|
AU2015210862B2
(en)
|
2014-01-31 |
2020-04-23 |
Cytomx Therapeutics, Inc |
Matriptase and u-plasminogen activator substrates and other cleavable moieties and methods of use thereof
|
IL247320B
(en)
|
2014-02-21 |
2022-09-01 |
Nektar Therapeutics |
Use of selective il-2r beta agonists in combination with antibodies against ctla-4 or pd-1 for cancer treatment
|
US10150802B2
(en)
|
2014-04-24 |
2018-12-11 |
The Board Of Trustees Of The Leland Stanford Junior University |
Superagonists, partial agonists and antagonists of interleukin-2
|
WO2016014974A2
(fr)
|
2014-07-25 |
2016-01-28 |
Cytomx Therapeutics, Inc. |
Anticorps anti-cd3, anticorps anti-cd3 activables, anticorps anti-cd3 multispécifiques, anticorps anti-cd3 activables multispécifiques et procédés d'utilisation de ces anticorps
|
MA41374A
(fr)
|
2015-01-20 |
2017-11-28 |
Cytomx Therapeutics Inc |
Substrats clivables par métalloprotéase matricielle et clivables par sérine protéase et procédés d'utilisation de ceux-ci
|
SG11201707383PA
(en)
|
2015-03-13 |
2017-10-30 |
Cytomx Therapeutics Inc |
Anti-pdl1 antibodies, activatable anti-pdl1 antibodies, and methods of use thereof
|
EP3292149B1
(fr)
|
2015-05-04 |
2021-12-01 |
CytomX Therapeutics, Inc. |
Anticorps anti-cd71 activables, et leurs méthodes d'utilisation
|
AU2016258988A1
(en)
|
2015-05-04 |
2017-12-07 |
Cytomx Therapeutics, Inc |
Anti-ITGa3 antibodies, activatable anti-ITGa3 antibodies, and methods of use thereof
|
CA2984948A1
(fr)
|
2015-05-04 |
2016-11-10 |
Cytomx Therapeutics, Inc. |
Anticorps anti-cd166, anticorps anti-cd166 activables, et leurs procedes d'utilisation
|
IL293719B2
(en)
|
2015-05-21 |
2023-07-01 |
Harpoon Therapeutics Inc |
Trispecific binding proteins and methods of use
|
WO2016200645A1
(fr)
|
2015-06-12 |
2016-12-15 |
Tianxin Wang |
Procédés pour la modification de protéines dans des applications pharmaceutiques
|
KR20180040138A
(ko)
|
2015-07-13 |
2018-04-19 |
싸이톰스 테라퓨틱스, 인크. |
항pd-1 항체, 활성화 가능한 항pd-1 항체, 및 이들의 사용 방법
|
MA43816A
(fr)
|
2016-03-08 |
2018-11-28 |
Maverick Therapeutics Inc |
Protéines de liaison inductibles et méthodes d'utilisation
|
US10100106B2
(en)
|
2016-05-20 |
2018-10-16 |
Harpoon Therapeutics, Inc. |
Single domain serum albumin binding protein
|
US20190225702A1
(en)
|
2016-10-14 |
2019-07-25 |
Harpoon Therapeutics, Inc. |
Innate immune cell trispecific binding proteins and methods of use
|
AU2017342559B2
(en)
|
2016-10-14 |
2022-03-24 |
Xencor, Inc. |
Bispecific heterodimeric fusion proteins containing IL-15/IL-15Ralpha Fc-fusion proteins and PD-1 antibody fragments
|
PE20191131A1
(es)
|
2016-11-03 |
2019-09-02 |
Bristol Myers Squibb Co |
Anticuerpos anti antigeno 4 del linfocito t citotoxico (ctla-4) activables y sus usos
|
WO2018136725A1
(fr)
|
2017-01-19 |
2018-07-26 |
Harpoon Therapeutics, Inc. |
Protéines de liaison inductibles pour les cellules immunitaires innées et méthodes d'utilisation
|
EP3589662A4
(fr)
|
2017-02-28 |
2020-12-30 |
Harpoon Therapeutics, Inc. |
Protéine monovalente inductible de fixation d' antigène
|
CN110366421A
(zh)
|
2017-03-01 |
2019-10-22 |
尼克塔治疗公司 |
使用白介素-2受体α,β选择性激动剂与过继性细胞转移疗法的组合的免疫***治疗方法
|
AU2018231127A1
(en)
|
2017-03-09 |
2019-09-19 |
Cytomx Therapeutics, Inc. |
CD147 antibodies, activatable CD147 antibodies, and methods of making and use thereof
|
KR20190141760A
(ko)
|
2017-05-02 |
2019-12-24 |
넥타르 테라퓨틱스 |
면역 요법적 종양 치료 방법
|
EP3619234A4
(fr)
*
|
2017-05-03 |
2021-05-26 |
Harpoon Therapeutics, Inc. |
Compositions et méthodes pour thérapies par cellules adoptives
|
MX2019013621A
(es)
|
2017-05-15 |
2020-01-13 |
Nektar Therapeutics |
Agonistas del receptor de interleuquina-15 de accion prolongada y composiciones y metodos inmunoterapeuticos relacionados.
|
BR112019025188A2
(pt)
|
2017-06-01 |
2020-06-23 |
Cytomx Therapeutics, Inc. |
Anticorpos anti-pdl1 ativáveis e métodos de uso dos mesmos
|
EP3641829A4
(fr)
|
2017-06-20 |
2021-04-21 |
The Board of Regents of The University of Texas System |
Promédicament d'interféron pour le traitement du cancer
|
EA202090247A1
(ru)
|
2017-07-14 |
2020-05-12 |
Цитомкс Терапьютикс, Инк. |
Антитела против cd166 и их применения
|
JP2020530554A
(ja)
|
2017-07-20 |
2020-10-22 |
シートムエックス セラピューティクス,インコーポレイテッド |
活性化抗体の特性を定性的および/または定量的に分析する方法およびその使用
|
EP3668548A2
(fr)
|
2017-08-17 |
2020-06-24 |
Nektar Therapeutics |
Méthode immunothérapeutique de traitement de tumeur
|
MX2020002198A
(es)
|
2017-08-30 |
2020-07-20 |
Cytomx Therapeutics Inc |
Anticuerpos anti-cd166 activables y métodos de uso de los mismos.
|
PE20212205A1
(es)
*
|
2017-09-08 |
2021-11-18 |
Maverick Therapeutics Inc |
Proteinas de union condicionalmente activadas restringidas
|
CN111315773A
(zh)
*
|
2017-09-08 |
2020-06-19 |
马弗里克治疗公司 |
含有Fc区的条件性活化的结合部分
|
JP7438106B2
(ja)
|
2017-10-14 |
2024-02-26 |
シートムエックス セラピューティクス,インコーポレイテッド |
抗体、活性化可能抗体、二重特異性抗体、および二重特異性活性化可能抗体ならびにその使用方法
|
EP3706770A4
(fr)
|
2017-11-07 |
2021-10-27 |
Nektar Therapeutics |
Polyimmunothérapies pour le traitement du cancer
|
JP2021515599A
(ja)
|
2018-03-09 |
2021-06-24 |
アスクジーン・ファーマ・インコーポレイテッドAskGene Pharma, Inc. |
新規のサイトカインプロドラッグ
|
CU24554B1
(es)
|
2018-05-07 |
2021-11-04 |
Ct Inmunologia Molecular |
Proteínas de fusión compuestas por una muteína de interleucina 2 e interferón tipo 1
|
ES2955511T3
(es)
*
|
2018-05-14 |
2023-12-04 |
Werewolf Therapeutics Inc |
Polipéptidos de interleucina 2 activables y métodos de uso de los mismos
|
JP2021524756A
(ja)
|
2018-05-14 |
2021-09-16 |
ウェアウルフ セラピューティクス, インコーポレイテッド |
活性化可能なサイトカインポリペプチド及びその使用方法
|
KR20210038548A
(ko)
|
2018-06-22 |
2021-04-07 |
큐진 인크. |
사이토카인-기반 생체활성 약물 및 이의 사용 방법
|
JP2022502088A
(ja)
|
2018-09-27 |
2022-01-11 |
エクシリオ デベロップメント, インコーポレイテッド |
マスクされたサイトカインポリペプチド
|
KR20220020879A
(ko)
|
2019-06-12 |
2022-02-21 |
에스크진 파마, 아이엔씨. |
새로운 il-15 프로드럭 및 이를 사용하는 방법
|
EP4004026A4
(fr)
|
2019-07-25 |
2023-11-15 |
Trutino Biosciences Inc. |
Promédicaments à base de cytokine d'il-2 comprenant un lieur clivable
|
US20220306714A1
(en)
|
2019-08-12 |
2022-09-29 |
AskGene Pharma, Inc. |
Il-2 fusion proteins that preferentially bind il-2ralpha
|
JP2023520517A
(ja)
|
2020-04-01 |
2023-05-17 |
エクシリオ デベロップメント, インコーポレイテッド |
マスクされたil-2サイトカイン及びその切断産物
|
TW202204386A
(zh)
|
2020-04-01 |
2022-02-01 |
美商艾希利歐發展股份有限公司 |
經遮蔽之il-12細胞激素及其裂解產物
|
BR112022019789A2
(pt)
|
2020-04-01 |
2022-11-16 |
Xilio Dev Inc |
Citocinas il-15 mascaradas, produtos de clivagem, ácido nucleico, vetor, célula hospedeira, composição, composição farmacêutica, kit e métodos de produção de uma citocina il-15 mascarada e de tratamento ou prevenção de câncer
|