IN2013MU02611A - - Google Patents
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- IN2013MU02611A IN2013MU02611A IN2611MU2013A IN2013MU02611A IN 2013MU02611 A IN2013MU02611 A IN 2013MU02611A IN 2611MU2013 A IN2611MU2013 A IN 2611MU2013A IN 2013MU02611 A IN2013MU02611 A IN 2013MU02611A
- Authority
- IN
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- Prior art keywords
- compounds
- diseases
- inhibitors
- janus kinase
- present
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/056—Ortho-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/08—Bridged systems
Abstract
ABSTRACT “NOVEL COMPOUNDS AS INHIBITORS OF JANUS KINASE” The present invention relates to compounds of general formula (1) that are inhibitors of Janus Kinase (JAK), a family of tyrosine kinases that are involved in inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6 or interferons. In particular, the compound of the invention inhibits JAK1 and/or JAK2 and/or JAK3 sub families. The present invention also provides methods for the production of the compounds of the invention, pharmaceutical compositions comprising the compounds of the invention, their tautomeric forms, and their pharmaceutically acceptable salts.
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2611MU2013 IN2013MU02611A (en) | 2013-08-07 | 2014-08-06 | |
PCT/IN2014/000515 WO2015019365A1 (en) | 2013-08-07 | 2014-08-06 | N-cyanomethylamides as inhibitors of janus kinase |
PT147938997T PT3030561T (en) | 2013-08-07 | 2014-08-06 | N-cyanomethylamides as inhibitors of janus kinase |
ES14793899.7T ES2618072T3 (en) | 2013-08-07 | 2014-08-06 | N-Cyanomethylamides as Janus kinase inhibitors |
HUE14793899A HUE033448T2 (en) | 2013-08-07 | 2014-08-06 | N-cyanomethylamides as inhibitors of janus kinase |
TW103126910A TWI562990B (en) | 2013-08-07 | 2014-08-06 | Novel compounds as inhibitors of janus kinase |
EP14793899.7A EP3030561B1 (en) | 2013-08-07 | 2014-08-06 | N-cyanomethylamides as inhibitors of janus kinase |
US14/910,028 US9556148B2 (en) | 2013-08-07 | 2014-08-06 | N-cyanomethylamides as inhibitors of janus kinase |
PL14793899T PL3030561T3 (en) | 2013-08-07 | 2014-08-06 | N-cyanomethylamides as inhibitors of janus kinase |
JP2016517296A JP2016525071A (en) | 2013-08-07 | 2014-08-06 | N-cyanomethylamide as an inhibitor of Janus kinase |
KR1020167005187A KR101665301B1 (en) | 2013-08-07 | 2014-08-06 | N-cyanomethylamides as inhibitors of janus kinase |
CN201480054915.9A CN105612154A (en) | 2013-08-07 | 2014-08-06 | N-cyanomethylamides as inhibitors of Janus Kinase |
DK14793899.7T DK3030561T3 (en) | 2013-08-07 | 2014-08-06 | N-CYANOMETHYLAMIDES AS INHIBITORS OF JANUS KINASE |
ARP140102982A AR097282A1 (en) | 2013-08-07 | 2014-08-07 | COMPOUNDS AS INHIBITORS OF THE JANUS QUINASA |
HK16110100.8A HK1222386A1 (en) | 2013-08-07 | 2016-08-24 | N-cyanomethylamides as inhibitors of janus kinase n- |
HRP20170277TT HRP20170277T1 (en) | 2013-08-07 | 2017-02-21 | N-cyanomethylamides as inhibitors of janus kinase |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2611MU2013 IN2013MU02611A (en) | 2013-08-07 | 2014-08-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
IN2013MU02611A true IN2013MU02611A (en) | 2015-06-12 |
Family
ID=54199342
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IN2611MU2013 IN2013MU02611A (en) | 2013-08-07 | 2014-08-06 |
Country Status (16)
Country | Link |
---|---|
US (1) | US9556148B2 (en) |
EP (1) | EP3030561B1 (en) |
JP (1) | JP2016525071A (en) |
KR (1) | KR101665301B1 (en) |
CN (1) | CN105612154A (en) |
AR (1) | AR097282A1 (en) |
DK (1) | DK3030561T3 (en) |
ES (1) | ES2618072T3 (en) |
HK (1) | HK1222386A1 (en) |
HR (1) | HRP20170277T1 (en) |
HU (1) | HUE033448T2 (en) |
IN (1) | IN2013MU02611A (en) |
PL (1) | PL3030561T3 (en) |
PT (1) | PT3030561T (en) |
TW (1) | TWI562990B (en) |
WO (1) | WO2015019365A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105801910A (en) * | 2016-06-01 | 2016-07-27 | 扬州兰都塑料科技有限公司 | Flame-retardant auxiliary for power cables |
US11034669B2 (en) | 2018-11-30 | 2021-06-15 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (32)
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IT1286302B1 (en) | 1996-04-10 | 1998-07-08 | Rotta Research Lab | CHINAZOLINE-4-AMINO-2- (PIPERIDINO-1-IL-4-SUBSTITUTED) WITH ANTI-HYPERTENSIVE ACTIVITY, PROCEDURE FOR THEIR PREPARATION AND USE |
ATE303987T1 (en) | 1999-05-24 | 2005-09-15 | Mitsubishi Pharma Corp | PHENOXYPROPYLAMIN DERIVATIVES |
GB0012240D0 (en) | 2000-05-19 | 2000-07-12 | Merck Sharp & Dohme | Therapeutic agents |
IL155443A0 (en) | 2000-11-02 | 2003-11-23 | Wyeth Corp | 1- aryl- or 1-alkylsulfonyl-heterocyclylbenzazoles as 5-hydroxytryptamine-6 ligands |
TW200407127A (en) | 2002-08-21 | 2004-05-16 | Astrazeneca Ab | Chemical compounds |
DE10250708A1 (en) | 2002-10-31 | 2004-05-19 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New alkyne compounds having MCH antagonist activity and medicaments containing these compounds |
ITMI20040954A1 (en) | 2004-05-12 | 2004-08-12 | Univ Degli Studi Milano | DERIVATIVES OF 3,6-DIAZABICICLO 3.1.I. HEPTANE WITH ANALGESIC ACTIVITY |
ES2427046T3 (en) | 2004-06-21 | 2013-10-28 | Galapagos N.V. | Methods and means for the treatment of osteoarthritis |
JP4624315B2 (en) | 2005-12-20 | 2011-02-02 | 株式会社リヒトラブ | Binding tool |
EP1979329A2 (en) | 2006-01-30 | 2008-10-15 | Exelixis, Inc. | 4-aryl-2-amino-pyrimidines or 4-aryl-2-aminoalkyl-pyrimidines as jak-2 modulators and methods of use |
EP2099454A4 (en) | 2006-11-17 | 2010-11-10 | Abbott Lab | Aminopyrrolidines as chemokine receptor antagonists |
PL2152701T3 (en) * | 2007-03-12 | 2016-10-31 | Phenyl amino pyrimidine compounds and uses thereof | |
EP2152079A4 (en) | 2007-06-04 | 2011-03-09 | Avila Therapeutics Inc | Heterocyclic compounds and uses thereof |
WO2009029998A1 (en) | 2007-09-06 | 2009-03-12 | Cytopia Research Pty Ltd | Retrometabolic compounds |
WO2009039257A1 (en) | 2007-09-19 | 2009-03-26 | Albemarle Corporation | Methods for production of 1,2,4-triazol-3-one |
US7989465B2 (en) | 2007-10-19 | 2011-08-02 | Avila Therapeutics, Inc. | 4,6-disubstituted pyrimidines useful as kinase inhibitors |
JP5600063B2 (en) | 2007-10-19 | 2014-10-01 | セルジーン アビロミクス リサーチ, インコーポレイテッド | Heteroaryl compounds and uses thereof |
WO2009103032A1 (en) * | 2008-02-15 | 2009-08-20 | Rigel Pharmaceuticals, Inc. | Pyrimidine-2-amine compounds and their use as inhibitors of jak kinases |
MY155639A (en) | 2008-04-16 | 2015-11-13 | Portola Pharm Inc | 2, 6-diamino-pyrimidin-5-yl-carboxamides as syk or jak kinases inhibitors |
CA2728893C (en) | 2008-04-16 | 2017-03-14 | Portola Pharmaceuticals, Inc. | Inhibitors of syk protein kinase |
DK2361248T3 (en) | 2008-06-27 | 2019-01-14 | Celgene Car Llc | Heteroberl compounds and uses thereof |
CA2736258C (en) | 2008-09-23 | 2016-11-29 | Rigel Pharmaceuticals, Inc. | Tricyclic carbamate jak inhibitors |
US8268851B2 (en) | 2008-12-23 | 2012-09-18 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the JAK pathway |
WO2010078369A2 (en) | 2008-12-30 | 2010-07-08 | Rigel Pharmaceuticals, Inc. | Pyrimidinediamine kinase inhibitors |
PE20150621A1 (en) | 2009-01-23 | 2015-05-07 | Rigel Pharmaceuticals Inc | DERIVATIVES OF 2,4-DIAMINE-PYRIMIDINE N2, N4-DISUSTITUTED AS JAK3 INHIBITORS |
TW201040162A (en) | 2009-05-06 | 2010-11-16 | Portola Pharm Inc | Inhibitors of JAK |
EP2438067B1 (en) | 2009-06-05 | 2015-08-26 | Boehringer Ingelheim International GmbH | Spirolactams as cgrp-antagonists |
MX337849B (en) | 2009-07-28 | 2016-03-09 | Rigel Pharmaceuticals Inc | Compositions and methods for inhibition of the jak pathway. |
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WO2013139717A1 (en) | 2012-03-19 | 2013-09-26 | Smardtv S.A. | A cicam system for processing multiple programme transport streams |
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2014
- 2014-08-06 WO PCT/IN2014/000515 patent/WO2015019365A1/en active Application Filing
- 2014-08-06 IN IN2611MU2013 patent/IN2013MU02611A/en unknown
- 2014-08-06 KR KR1020167005187A patent/KR101665301B1/en active IP Right Grant
- 2014-08-06 ES ES14793899.7T patent/ES2618072T3/en active Active
- 2014-08-06 EP EP14793899.7A patent/EP3030561B1/en active Active
- 2014-08-06 US US14/910,028 patent/US9556148B2/en not_active Expired - Fee Related
- 2014-08-06 DK DK14793899.7T patent/DK3030561T3/en active
- 2014-08-06 PL PL14793899T patent/PL3030561T3/en unknown
- 2014-08-06 TW TW103126910A patent/TWI562990B/en not_active IP Right Cessation
- 2014-08-06 CN CN201480054915.9A patent/CN105612154A/en active Pending
- 2014-08-06 PT PT147938997T patent/PT3030561T/en unknown
- 2014-08-06 HU HUE14793899A patent/HUE033448T2/en unknown
- 2014-08-06 JP JP2016517296A patent/JP2016525071A/en not_active Ceased
- 2014-08-07 AR ARP140102982A patent/AR097282A1/en unknown
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2016
- 2016-08-24 HK HK16110100.8A patent/HK1222386A1/en unknown
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2017
- 2017-02-21 HR HRP20170277TT patent/HRP20170277T1/en unknown
Also Published As
Publication number | Publication date |
---|---|
US9556148B2 (en) | 2017-01-31 |
CN105612154A (en) | 2016-05-25 |
TWI562990B (en) | 2016-12-21 |
PT3030561T (en) | 2017-03-23 |
AR097282A1 (en) | 2016-03-02 |
DK3030561T3 (en) | 2017-03-27 |
WO2015019365A1 (en) | 2015-02-12 |
EP3030561A1 (en) | 2016-06-15 |
ES2618072T3 (en) | 2017-06-20 |
EP3030561B1 (en) | 2017-01-11 |
US20160176849A1 (en) | 2016-06-23 |
KR20160030580A (en) | 2016-03-18 |
TW201518290A (en) | 2015-05-16 |
KR101665301B1 (en) | 2016-10-11 |
HK1222386A1 (en) | 2017-06-30 |
WO2015019365A8 (en) | 2016-02-18 |
JP2016525071A (en) | 2016-08-22 |
PL3030561T3 (en) | 2017-08-31 |
HUE033448T2 (en) | 2017-11-28 |
HRP20170277T1 (en) | 2017-05-19 |
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