SG10201407409WA - Inhibitors of jun n-terminal kinase - Google Patents

Inhibitors of jun n-terminal kinase

Info

Publication number
SG10201407409WA
SG10201407409WA SG10201407409WA SG10201407409WA SG10201407409WA SG 10201407409W A SG10201407409W A SG 10201407409WA SG 10201407409W A SG10201407409W A SG 10201407409WA SG 10201407409W A SG10201407409W A SG 10201407409WA SG 10201407409W A SG10201407409W A SG 10201407409WA
Authority
SG
Singapore
Prior art keywords
jun
inhibitors
present disclosure
terminal kinase
compounds
Prior art date
Application number
SG10201407409WA
Other languages
English (en)
Inventor
Hing L Sham
Andrei W Konradi
Roy K Hom
Gary D Probst
Simeon Bowers
Anh Truong
R Jeffrey Neitz
Jennifer Sealy
Gergely Toth
Original Assignee
Elan Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Pharm Inc filed Critical Elan Pharm Inc
Publication of SG10201407409WA publication Critical patent/SG10201407409WA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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