SE8601646D0 - Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof - Google Patents

Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof

Info

Publication number: SE8601646D0
Authority: SE; Sweden
Prior art keywords: epipodophyllotoxin; intermediates; processes; preparation; production
Prior art date: 1985-04-12

Application number

SE8601646A

Other languages

English (en)

Other versions

SE468768B (sv

SE8601646L (sv

Inventor

D M Vyas

P M Skonezny

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-04-12

Filing date

1986-04-11

Publication date

1986-04-11

1986-04-11 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1986-04-11 Publication of SE8601646D0 publication Critical patent/SE8601646D0/sv

1986-11-28 Publication of SE8601646L publication Critical patent/SE8601646L/sv

1993-03-15 Publication of SE468768B publication Critical patent/SE468768B/sv

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/353—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by isomerisation; by change of size of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/377—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds
- C07C62/32—Unsaturated compounds containing hydroxy or O-metal groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds
- C07C62/34—Unsaturated compounds containing ether groups, groups, groups, or groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Oil, Petroleum & Natural Gas (AREA)
Biotechnology (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

SE8601646A 1985-04-12 1986-04-11 Mellanprodukter foer framstaellning av epipodofyllotoxin och beslaektade foereningar och foerfaranden foer framstaellning daerav SE468768B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/722,932 US4644072A (en)	1985-04-12	1985-04-12	Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof

Publications (3)

Publication Number	Publication Date
SE8601646D0 true SE8601646D0 (sv)	1986-04-11
SE8601646L SE8601646L (sv)	1986-11-28
SE468768B SE468768B (sv)	1993-03-15

Family

ID=24904037

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
SE8601646A SE468768B (sv)	1985-04-12	1986-04-11	Mellanprodukter foer framstaellning av epipodofyllotoxin och beslaektade foereningar och foerfaranden foer framstaellning daerav
SE9202476A SE9202476A0 (sv)	1985-04-12	1992-08-28	Mellanprodukter för framställning av epipodofyllotoxin och besläktade föreningar och förfaranden för framställning och användning därav

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
SE9202476A SE9202476A0 (sv)	1985-04-12	1992-08-28	Mellanprodukter för framställning av epipodofyllotoxin och besläktade föreningar och förfaranden för framställning och användning därav

Country Status (33)

Country	Link
US (1)	US4644072A (sv)
JP (1)	JPS61238758A (sv)
KR (1)	KR900005624B1 (sv)
CN (2)	CN1021822C (sv)
AT (1)	ATA96986A (sv)
AU (6)	AU587021B2 (sv)
BE (1)	BE904587A (sv)
CA (1)	CA1275651C (sv)
CH (2)	CH669190A5 (sv)
CY (1)	CY1599A (sv)
DE (1)	DE3612278A1 (sv)
DK (2)	DK167986A (sv)
EG (1)	EG18077A (sv)
ES (2)	ES8802044A1 (sv)
FI (1)	FI861508A (sv)
FR (1)	FR2587335B1 (sv)
GB (1)	GB2176181B (sv)
GR (1)	GR860982B (sv)
HK (1)	HK53391A (sv)
HU (4)	HU198063B (sv)
IE (1)	IE59039B1 (sv)
IL (1)	IL78451A0 (sv)
IT (1)	IT1208593B (sv)
LU (1)	LU86392A1 (sv)
MY (1)	MY101618A (sv)
NL (1)	NL8600938A (sv)
PT (1)	PT82383B (sv)
RU (1)	RU1819265C (sv)
SE (2)	SE468768B (sv)
SG (1)	SG44791G (sv)
SU (1)	SU1547707A3 (sv)
YU (2)	YU44785B (sv)
ZA (1)	ZA862747B (sv)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4644072A (en) *	1985-04-12	1987-02-17	Bristol-Myers Company	Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
US5011948A (en) *	1985-04-12	1991-04-30	Bristol-Myers Company	Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
US5106996A (en) *	1985-12-05	1992-04-21	Bristol-Myers Company	Process for the preparation of podophyllotoxin
US5013851A (en) *	1985-12-05	1991-05-07	Bristol-Myers Company	Intermediates for the production of podophyllotoxin and related compounds
US4734512A (en) *	1985-12-05	1988-03-29	Bristol-Myers Company	Intermediates for the production of podophyllotoxin and related compounds and processes for the preparation and use thereof
US5840900A (en) *	1993-10-20	1998-11-24	Enzon, Inc.	High molecular weight polymer-based prodrugs
US5880131A (en) *	1993-10-20	1999-03-09	Enzon, Inc.	High molecular weight polymer-based prodrugs
US5605976A (en) *	1995-05-15	1997-02-25	Enzon, Inc.	Method of preparing polyalkylene oxide carboxylic acids
GB9422947D0 (en) *	1994-11-14	1995-01-04	Univ Salamanca	Immunosuppressive cyclolignan derivatives
ATE186054T1 (de) *	1995-06-30	1999-11-15	Cerbios Pharma Sa	Glykoside, deren zuckerfreie abbauprodukte und derivate derselben
US6051721A (en) *	1997-10-02	2000-04-18	The Board Of Regents Of The University Of Nebraska	Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis
EP2289549A3 (en)	1999-10-01	2011-06-15	Immunogen, Inc.	Immunoconjugates for treating cancer
JOP20190254A1 (ar)	2017-04-27	2019-10-27	Pharma Mar Sa	مركبات مضادة للأورام

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL6613143A (sv) *	1965-09-21	1967-03-22
US3716574A (en) *	1967-12-01	1973-02-13	Rayonier Inc	Pure crystalline plicatic acid tetrahydrate and the methyl ester thereof
US4122092A (en) *	1977-08-25	1978-10-24	University Of Rochester	Total synthesis of (±)-picropodophyllone and (±)-4'-demethylpicropodophyllone
US4294763A (en) *	1980-03-05	1981-10-13	University Of Rochester	Intermediates for the production of picropodophyllin and related compounds and processes for the preparation and use thereof
US4391982A (en) *	1980-03-05	1983-07-05	The University Of Rochester	Intermediates for the production of picropodophyllin and related compounds and processes for the preparation and use thereof
WO1986004062A1 (en) *	1984-12-28	1986-07-17	Conpharm Ab	Pharmaceutically active compound and a method for its preparation
NO170760C (no) *	1985-01-10	1992-12-02	Tanabe Seiyaku Co	Analogifremgangsmaate for fremstilling av terapeutisk aktive nafthalenderivater
US4644072A (en) *	1985-04-12	1987-02-17	Bristol-Myers Company	Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
US4734512A (en) *	1985-12-05	1988-03-29	Bristol-Myers Company	Intermediates for the production of podophyllotoxin and related compounds and processes for the preparation and use thereof

1985
- 1985-04-12 US US06/722,932 patent/US4644072A/en not_active Expired - Fee Related
1986
- 1986-04-04 FR FR868604873A patent/FR2587335B1/fr not_active Expired - Fee Related
- 1986-04-08 IL IL78451A patent/IL78451A0/xx unknown
- 1986-04-09 FI FI861508A patent/FI861508A/fi not_active Application Discontinuation
- 1986-04-10 ES ES553868A patent/ES8802044A1/es not_active Expired
- 1986-04-10 EG EG197/86A patent/EG18077A/xx active
- 1986-04-11 AU AU55993/86A patent/AU587021B2/en not_active Ceased
- 1986-04-11 SE SE8601646A patent/SE468768B/sv not_active IP Right Cessation
- 1986-04-11 CH CH1455/86A patent/CH669190A5/de not_active IP Right Cessation
- 1986-04-11 CN CN86102404A patent/CN1021822C/zh not_active Expired - Fee Related
- 1986-04-11 HU HU863527A patent/HU198063B/hu not_active IP Right Cessation
- 1986-04-11 CH CH490/89A patent/CH672635A5/de not_active IP Right Cessation
- 1986-04-11 DE DE19863612278 patent/DE3612278A1/de not_active Ceased
- 1986-04-11 CA CA000506409A patent/CA1275651C/en not_active Expired - Fee Related
- 1986-04-11 IE IE95586A patent/IE59039B1/en not_active IP Right Cessation
- 1986-04-11 HU HU873238A patent/HU204044B/hu not_active IP Right Cessation
- 1986-04-11 ZA ZA862747A patent/ZA862747B/xx unknown
- 1986-04-11 LU LU86392A patent/LU86392A1/fr unknown
- 1986-04-11 KR KR1019860002773A patent/KR900005624B1/ko not_active IP Right Cessation
- 1986-04-11 JP JP61084008A patent/JPS61238758A/ja active Pending
- 1986-04-11 HU HU861538A patent/HU199846B/hu not_active IP Right Cessation
- 1986-04-11 BE BE0/216525A patent/BE904587A/fr not_active IP Right Cessation
- 1986-04-11 IT IT8620048A patent/IT1208593B/it active
- 1986-04-11 RU SU864027396A patent/RU1819265C/ru active
- 1986-04-11 HU HU883526A patent/HU201541B/hu not_active IP Right Cessation
- 1986-04-11 DK DK167986A patent/DK167986A/da not_active IP Right Cessation
- 1986-04-11 GB GB8608808A patent/GB2176181B/en not_active Expired
- 1986-04-14 YU YU594/86A patent/YU44785B/xx unknown
- 1986-04-14 AT AT0096986A patent/ATA96986A/de not_active Application Discontinuation
- 1986-04-14 GR GR860982A patent/GR860982B/el unknown
- 1986-04-14 NL NL8600938A patent/NL8600938A/nl not_active Application Discontinuation
- 1986-04-14 PT PT82383A patent/PT82383B/pt not_active IP Right Cessation
1987
- 1987-02-10 SU SU874028952A patent/SU1547707A3/ru active
- 1987-06-16 YU YU112487A patent/YU46212B/sh unknown
- 1987-10-01 MY MYPI87002724A patent/MY101618A/en unknown
- 1987-10-16 ES ES557772A patent/ES8900046A1/es not_active Expired
1989
- 1989-06-09 AU AU36286/89A patent/AU617184B2/en not_active Ceased
- 1989-06-09 AU AU36285/89A patent/AU617183B2/en not_active Ceased
- 1989-06-09 AU AU36288/89A patent/AU617185B2/en not_active Ceased
- 1989-06-09 AU AU36287/89A patent/AU607337B2/en not_active Ceased
- 1989-06-09 AU AU36284/89A patent/AU617182B2/en not_active Ceased
1991
- 1991-06-15 SG SG44791A patent/SG44791G/en unknown
- 1991-07-11 HK HK533/91A patent/HK53391A/xx unknown
- 1991-10-10 CN CN91109623A patent/CN1059520A/zh active Pending
1992
- 1992-04-03 CY CY1599A patent/CY1599A/xx unknown
- 1992-08-28 SE SE9202476A patent/SE9202476A0/sv unknown
1993
- 1993-10-18 DK DK117193A patent/DK117193A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
ATA96986A (de)	1994-05-15
EG18077A (en)	1991-08-30
AU3628589A (en)	1989-10-05
GB2176181A (en)	1986-12-17
YU59486A (en)	1988-02-29
AU617183B2 (en)	1991-11-21
SE9202476D0 (sv)	1992-08-28
CA1275651C (en)	1990-10-30
KR860008198A (ko)	1986-11-12
DK167986D0 (da)	1986-04-11
HU198063B (en)	1989-07-28
HU201541B (en)	1990-11-28
LU86392A1 (fr)	1986-11-05
IE860955L (en)	1986-10-12
IT1208593B (it)	1989-07-10
AU587021B2 (en)	1989-08-03
ES553868A0 (es)	1988-03-16
CN1059520A (zh)	1992-03-18
ES557772A0 (es)	1988-11-16
GB2176181B (en)	1989-06-28
HUT44773A (en)	1988-04-28
AU5599386A (en)	1986-10-16
GB8608808D0 (en)	1986-05-14
US4644072A (en)	1987-02-17
IT8620048A0 (it)	1986-04-11
DK117193D0 (da)	1993-10-18
PT82383A (en)	1986-05-01
FI861508A0 (fi)	1986-04-09
YU44785B (en)	1991-02-28
HK53391A (en)	1991-07-19
CH669190A5 (de)	1989-02-28
ES8802044A1 (es)	1988-03-16
FI861508A (fi)	1986-10-13
AU3628689A (en)	1989-10-05
YU46212B (sh)	1993-05-28
CH672635A5 (sv)	1989-12-15
PT82383B (pt)	1988-10-14
DK167986A (da)	1986-10-13
AU3628789A (en)	1989-10-05
MY101618A (en)	1991-12-17
BE904587A (fr)	1986-10-13
SG44791G (en)	1991-07-26
HU199846B (en)	1990-03-28
YU112487A (en)	1988-02-29
KR900005624B1 (ko)	1990-08-01
SE468768B (sv)	1993-03-15
AU607337B2 (en)	1991-02-28
RU1819265C (ru)	1993-05-30
SE9202476A0 (sv)	1992-08-28
HUT47071A (en)	1989-01-30
AU617185B2 (en)	1991-11-21
FR2587335A1 (fr)	1987-03-20
CY1599A (en)	1992-04-03
SE8601646L (sv)	1986-11-28
AU617184B2 (en)	1991-11-21
DE3612278A1 (de)	1986-10-16
ES8900046A1 (es)	1988-11-16
IE59039B1 (en)	1993-12-15
CN1021822C (zh)	1993-08-18
HUT47088A (en)	1989-01-30
HU204044B (en)	1991-11-28
SU1547707A3 (ru)	1990-02-28
AU617182B2 (en)	1991-11-21
CN86102404A (zh)	1986-12-03
FR2587335B1 (fr)	1990-09-14
AU3628889A (en)	1989-10-05
AU3628489A (en)	1989-10-05
JPS61238758A (ja)	1986-10-24
NL8600938A (nl)	1986-11-03
GR860982B (en)	1986-09-01
DK117193A (da)	1993-10-18
ZA862747B (en)	1986-11-26
IL78451A0 (en)	1986-08-31

Legal Events

Date

Code

Title

Description

1995-01-31

NUG

Patent has lapsed

Ref document number: 8601646-6

Effective date: 19941110

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Publication	Publication Date	Title
FI852974A0 (fi)	1985-08-01	Nya n-hydroxylgruppen skyddande grupper och framstaellningsfoerfarande foer 3-acylamino-1-hydroxi-2-azetidinoner.
MX5680E (es)	1983-12-08	Procedimiento para la preparacion de 2-(2-alcoxietil)-2'-hidroxi-6,7-benzomorfanos
SE8601646D0 (sv)	1986-04-11	Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
FI861506A (fi)	1986-10-12	Foerfarande foer framstaellning av 1,2-ditiolan-3-pentansyra (tioktsyra).
ES2000604A6 (es)	1988-03-01	Un procedimiento para preparar aril-piperidin esteres
PT81122B (pt)	1988-01-22	Processo para a preparacao de derivados de benzil-ftalazinona substituidos
FI875596A (fi)	1988-06-24	Foerfarande foer framstaellning av tienyletylaminer och aeven ditienyletylaminer.
DE60235365D1 (de)	2010-04-01	Verfahren zur herstellung von 7-amino-syn-3,5-dihydroxyheptansäurederivaten und zwischenverbindungen diesesverfahrens und deren herestellung
SE9101482D0 (sv)	1991-05-16	Foerfarande foer framstaellning av mellanprodukter anvaendbara foer syntes av bensotiazepiner
ES544753A0 (es)	1986-09-16	Un procedimiento para la preparacion de carbapenems.
NO871575D0 (no)	1987-04-14	Fremgangsmaate for fremstilling av 1,5-benztiazepinderivater.
PT80791A (fr)	1985-08-01	Procede de preparation de nouvelles phenyl-naphtiridines utiles notamment comme medicaments anti-ulceres
ES8106703A1 (es)	1981-08-01	Un procedimiento de preparacion de una 7-acilindolin-2-ona
PT85635A (en)	1987-10-01	Process for the preparation of 2-cyano-2-alkoximino-acetamides having a fungicidal effect and of intermediates
DK222087A (da)	1987-04-30	Aeny fremgangsmaade til fremstilling af kemiske for-bindelserae
DE3469527D1 (en)	1988-04-07	Nortropine derivative, process for its preparation and its use
DE59406704D1 (de)	1998-09-24	Verfahren zur Herstellung von gegebenenfalls 2-substituierten 5-Chlorimidazol-4-carbaldehyden
FI904033A0 (fi)	1990-08-15	Nya 1,3-oxaziner.
ES2001701A6 (es)	1988-06-01	Un metodo para preparar compuesto de benzoilurea
DK0555283T3 (da)	1995-07-03	Mellemprodukter ved fremstillingen af 4,5-difluoranthranilinsyre
FI863897A (fi)	1988-03-27	Kemiskt foerfarande.