FI861506A - Foerfarande foer framstaellning av 1,2-ditiolan-3-pentansyra (tioktsyra). - Google Patents
Foerfarande foer framstaellning av 1,2-ditiolan-3-pentansyra (tioktsyra). Download PDFInfo
- Publication number
- FI861506A FI861506A FI861506A FI861506A FI861506A FI 861506 A FI861506 A FI 861506A FI 861506 A FI861506 A FI 861506A FI 861506 A FI861506 A FI 861506A FI 861506 A FI861506 A FI 861506A
- Authority
- FI
- Finland
- Prior art keywords
- thioctsyra
- pentansyra
- ditiolan
- foerfarande foer
- foer framstaellning
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Mechanical Treatment Of Semiconductor (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19853512911 DE3512911A1 (de) | 1985-04-11 | 1985-04-11 | Verfahren zur herstellung von 1,2-dithiolan-3-pentansaeure (thioctsaeure) |
Publications (2)
Publication Number | Publication Date |
---|---|
FI861506A0 FI861506A0 (fi) | 1986-04-09 |
FI861506A true FI861506A (fi) | 1986-10-12 |
Family
ID=6267677
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI861506A FI861506A (fi) | 1985-04-11 | 1986-04-09 | Foerfarande foer framstaellning av 1,2-ditiolan-3-pentansyra (tioktsyra). |
Country Status (9)
Country | Link |
---|---|
US (3) | US4705867A (fi) |
EP (1) | EP0197407B1 (fi) |
JP (2) | JPS61236775A (fi) |
AT (1) | ATE47138T1 (fi) |
DD (1) | DD251750A5 (fi) |
DE (2) | DE3512911A1 (fi) |
ES (1) | ES8703451A1 (fi) |
FI (1) | FI861506A (fi) |
HU (1) | HUT40638A (fi) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3629116A1 (de) * | 1986-08-27 | 1988-03-10 | Asta Pharma Ag | Verfahren zur herstellung enantiomerenreiner r-(+)-(alpha)-liponsaeure und s-(-)-(alpha)-liponsaeure (thioctsaeure) sowie nonen- beziehungsweise mesylderivate als zwischenprodukte hierfuer |
EP0812590A3 (de) | 1989-11-09 | 1999-06-09 | ASTA Medica Aktiengesellschaft | Verwendung von R-Alpha-Liponsäure zur Zytoprotektion |
PT95827B (pt) * | 1989-11-09 | 1997-11-28 | Asta Medica Ag | Processo para a preparacao de composicoes farmaceuticas para combater retrovirus, contendo como ingredientes activos acidos carboxilicos com enxofre |
DE4037440A1 (de) * | 1990-11-24 | 1992-05-27 | Basf Ag | Verfahren zur herstellung von (6s)-6,8-dihydroxyoctansaeureestern |
DE4229914A1 (de) * | 1992-09-08 | 1994-03-10 | Basf Ag | Verbessertes Verfahren zur Herstellung von R/S-Ï-Liponsäure oder R/S-â-Liponsäure |
DE9213914U1 (de) * | 1992-10-15 | 1992-12-03 | Asta Medica AG, 6000 Frankfurt | Ampulle und Infusionslösung von Thioctsäure in Form der wasserlöslichen Salze der Thioctsäure |
EP0855396A1 (en) * | 1997-01-22 | 1998-07-29 | ASTA Medica Aktiengesellschaft | Thioctic acid metabolites and methods of use thereof |
US6197340B1 (en) | 1998-05-28 | 2001-03-06 | Medical Research Institute | Controlled release lipoic acid |
US20040259895A1 (en) * | 1998-05-28 | 2004-12-23 | Medical Research Institute | Oral formulation of lipid soluble thiamine and lipoic acid |
US20050085498A1 (en) * | 1998-05-28 | 2005-04-21 | Byrd Edward A. | Oral formulation of lipid soluble thiamine, lipoic acid, creatine derivative, and L-arginine alpha-ketoglutarate |
US6905707B2 (en) * | 1998-05-28 | 2005-06-14 | Medical Research Institute | Controlled release arginine alpha ketoglutarate |
US6191162B1 (en) | 1998-05-28 | 2001-02-20 | Medical Research Institute | Method of reducing serum glucose levels |
WO2000024734A1 (en) * | 1998-10-26 | 2000-05-04 | The Research Foundation Of State University Of New York | Lipoic acid derivatives and their use in treatment of disease |
US6664287B2 (en) * | 2000-03-15 | 2003-12-16 | Bethesda Pharmaceuticals, Inc. | Antioxidants |
US20070272320A1 (en) * | 2006-05-24 | 2007-11-29 | James Roberson | Reusable duct wrap |
WO2008131114A2 (en) * | 2007-04-18 | 2008-10-30 | Cornerstone Pharmaceuticals, Inc. | Pharmaceutical formulations containing lipoic acid derivatives |
BRPI0810660A2 (pt) | 2007-04-18 | 2014-10-07 | Cornerstone Pharmaceuticals Inc | Derivados do ácido lipóico |
US8263653B2 (en) | 2007-04-18 | 2012-09-11 | Cornerstone Pharmaceuticals, Inc. | Pharmaceutical formulations containing lipoic acid derivatives |
WO2010065069A2 (en) * | 2008-12-01 | 2010-06-10 | In Vasc Therapeutics, Inc. | Compositions comprising renin-angiotensin aldosterone system inhibitors and lipoic acid compounds, and the use thereof for the treatment of renin-angiotensin aldosterone system related disorders |
ES2747702T3 (es) | 2014-06-19 | 2020-03-11 | Rafael Pharmaceuticals Inc | Compuestos farmacéuticos |
WO2015195070A1 (en) | 2014-06-19 | 2015-12-23 | Robert Shorr | Pharmaceutical compounds |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB762575A (en) * | 1952-04-24 | 1956-11-28 | American Cyanamid Co | Omega [3-(1,2-dithiolanyl)] aliphatic acids, salts and esters and the preparation thereof |
US2752373A (en) * | 1952-12-10 | 1956-06-26 | Du Pont | Process for preparing 6, 8-dithiooctanoic acid |
US2752374A (en) * | 1952-12-10 | 1956-06-26 | Du Pont | Preparation of acids having thiol groups on the ultimate and antepenultimate carbons from the carboxyl |
US2828321A (en) * | 1953-10-19 | 1958-03-25 | American Cyanamid Co | Keto aliphatic acid esters and method of preparing the same |
US2828322A (en) * | 1953-10-19 | 1958-03-25 | American Cyanamid Co | Hydroxy thioaliphatic acids and methods of preparing the same |
US2809978A (en) * | 1953-12-04 | 1957-10-15 | Merck & Co Inc | Intermediates useful in the synthesis of alpha-lipoic acid |
US3002011A (en) * | 1953-12-04 | 1961-09-26 | Merck & Co Inc | Intermediates and processes for producing alpha-lipoic acid |
US2853497A (en) * | 1953-12-04 | 1958-09-23 | Merck & Co Inc | 6, 8-bis (hydrocarbon substituted mercapto) 5-hydroxycaprylic acids and delta-lactones thereof |
US3049549A (en) * | 1954-03-22 | 1962-08-14 | Research Corp | Lipoic acid and derivatives |
US2789991A (en) * | 1954-05-20 | 1957-04-23 | American Cyanamid Co | Substituted disulfones |
US2792406A (en) * | 1954-06-01 | 1957-05-14 | Du Pont | Process of preparing alpha-lipoic acid using dichlorooctanoate and metal disulfide |
US2980716A (en) * | 1954-06-11 | 1961-04-18 | Research Corp | Method for preparing 6, 8-dihalooctanoic esters |
US2975198A (en) * | 1954-07-08 | 1961-03-14 | Research Corp | Lipoic acid intermediates |
US3033882A (en) * | 1958-04-17 | 1962-05-08 | Rech S Et Propagande Scient | Octanoic esters and processes for their preparation and utilization |
US3223712A (en) * | 1960-07-18 | 1965-12-14 | Yamanouchi Pharma Co Ltd | Synthesis of thioctic acid and thioctic acid amide |
-
1985
- 1985-04-11 DE DE19853512911 patent/DE3512911A1/de not_active Withdrawn
-
1986
- 1986-03-22 EP EP86103974A patent/EP0197407B1/de not_active Expired
- 1986-03-22 DE DE8686103974T patent/DE3666226D1/de not_active Expired
- 1986-03-22 AT AT86103974T patent/ATE47138T1/de not_active IP Right Cessation
- 1986-04-04 US US06/848,212 patent/US4705867A/en not_active Expired - Lifetime
- 1986-04-09 FI FI861506A patent/FI861506A/fi not_active IP Right Cessation
- 1986-04-09 JP JP61080291A patent/JPS61236775A/ja active Granted
- 1986-04-09 DD DD86288945A patent/DD251750A5/de unknown
- 1986-04-10 ES ES553850A patent/ES8703451A1/es not_active Expired
- 1986-04-10 HU HU861516A patent/HUT40638A/hu unknown
-
1987
- 1987-07-15 US US07/073,820 patent/US4800044A/en not_active Expired - Lifetime
- 1987-07-15 US US07/073,584 patent/US4966732A/en not_active Expired - Lifetime
- 1987-11-20 JP JP62292234A patent/JPS63183558A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPH0351702B2 (fi) | 1991-08-07 |
DE3666226D1 (en) | 1989-11-16 |
US4966732A (en) | 1990-10-30 |
US4705867A (en) | 1987-11-10 |
JPS61236775A (ja) | 1986-10-22 |
DD251750A5 (de) | 1987-11-25 |
ES553850A0 (es) | 1987-02-16 |
ATE47138T1 (de) | 1989-10-15 |
ES8703451A1 (es) | 1987-02-16 |
US4800044A (en) | 1989-01-24 |
EP0197407A3 (en) | 1987-09-02 |
JPS63183558A (ja) | 1988-07-28 |
EP0197407A2 (de) | 1986-10-15 |
DE3512911A1 (de) | 1986-10-16 |
JPH0348188B2 (fi) | 1991-07-23 |
EP0197407B1 (de) | 1989-10-11 |
HUT40638A (en) | 1987-01-28 |
FI861506A0 (fi) | 1986-04-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI861506A0 (fi) | Foerfarande foer framstaellning av 1,2-ditiolan-3-pentansyra (tioktsyra). | |
AU537414B2 (en) | Pyroglutamic acid derivatives | |
FI852974L (fi) | Nya n-hydroxylgruppen skyddande grupper och framstaellningsfoerfarande foer 3-acylamino-1-hydroxi-2-azetidinoner. | |
FI875059A (fi) | Foereningar. | |
ES2061432T3 (es) | Nuevas amidas de acido acrilico. | |
GR69233B (fi) | ||
GB8630702D0 (en) | Quinoline compound | |
ES2031892T3 (es) | Agentes antialergicos y antiinflamatorios. | |
AU1395283A (en) | 1-carboxyalkanoylindoline-2-carboxylic acid esters | |
ATE86860T1 (de) | Praeparat gegen ulcus. | |
DK113183D0 (da) | Kroneetherforbindelser, deres fremstilling og anvendelse | |
ES8705853A1 (es) | Un procedimiento para la produccion de derivados de benzoilurea | |
FI842112A (fi) | Foerfarande foer framstaellning av -karbolin-3-karboxylsyraderivat. | |
GR3005920T3 (fi) | ||
HK64691A (en) | Anticonvulsant agents | |
ES464483A1 (es) | Procedimiento para la obtencion de ortoaminoacetofenonas. | |
IL75430A (en) | Pineapple ketone carbonate derivatives and their use as flavoring agents | |
ATE36536T1 (de) | Phosphoroimidate. | |
ES8703421A1 (es) | Procedimiento para preparar derivados de pirrolidindiona. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM | Patent lapsed |
Owner name: DEGUSSA AKTIENGESELLSCHAFT |