HU171662B - Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh apovinkaminola i ikh kislotnykh adduktov - Google Patents

Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh apovinkaminola i ikh kislotnykh adduktov

Info

Publication number
HU171662B
HU171662B HU75RI00000573A HURI000573A HU171662B HU 171662 B HU171662 B HU 171662B HU 75RI00000573 A HU75RI00000573 A HU 75RI00000573A HU RI000573 A HURI000573 A HU RI000573A HU 171662 B HU171662 B HU 171662B
Authority
HU
Hungary
Prior art keywords
apovincaminol
acid addition
addition salts
optically active
active derivatives
Prior art date
Application number
HU75RI00000573A
Other languages
English (en)
Inventor
Csaba Loerincz
Maria Bolyos
Kalman Szasz
Laszlo Szporny
Egon Karpati
Eva Palosi
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Priority to HU75RI00000573A priority Critical patent/HU171662B/hu
Priority to US05/703,207 priority patent/US4108996A/en
Priority to AT495876A priority patent/AT350736B/de
Priority to FR7621439A priority patent/FR2317930A1/fr
Priority to SE7608049A priority patent/SE423097B/xx
Priority to GB29501/76A priority patent/GB1525640A/en
Priority to BE168989A priority patent/BE844229A/xx
Priority to DE2632118A priority patent/DE2632118C3/de
Priority to JP51084514A priority patent/JPS5212199A/ja
Priority to PL1976191255A priority patent/PL100426B1/pl
Publication of HU171662B publication Critical patent/HU171662B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU75RI00000573A 1975-07-18 1975-07-18 Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh apovinkaminola i ikh kislotnykh adduktov HU171662B (hu)

Priority Applications (10)

Application Number Priority Date Filing Date Title
HU75RI00000573A HU171662B (hu) 1975-07-18 1975-07-18 Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh apovinkaminola i ikh kislotnykh adduktov
US05/703,207 US4108996A (en) 1975-07-18 1976-07-07 (-)-Apovincaminol lauric acid ester and cerebral vasodilatory composition thereof
AT495876A AT350736B (de) 1975-07-18 1976-07-07 Verfahren zur herstellung von neuen apovin- caminolestern
FR7621439A FR2317930A1 (fr) 1975-07-18 1976-07-13 Nouveaux derives d'apovincaminol, leur procede de preparation et leur application
SE7608049A SE423097B (sv) 1975-07-18 1976-07-14 Analogiforfarande for framstellning av apovinkaminoestrar
GB29501/76A GB1525640A (en) 1975-07-18 1976-07-15 Apovincaminol derivatives and a process for the preparation thereof
BE168989A BE844229A (fr) 1975-07-18 1976-07-16 Nouveaux derives d'apovincaminol leur procede de preparation et leur application
DE2632118A DE2632118C3 (de) 1975-07-18 1976-07-16 Apovincaminolester und Verfahren zu deren Herstellung und Arzneimittel
JP51084514A JPS5212199A (en) 1975-07-18 1976-07-17 Production of apobincaminol derivative and pharmaceutical preparation containig same
PL1976191255A PL100426B1 (pl) 1975-07-18 1976-07-17 Sposob wytwarzania estrow apowinkaminolu

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU75RI00000573A HU171662B (hu) 1975-07-18 1975-07-18 Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh apovinkaminola i ikh kislotnykh adduktov

Publications (1)

Publication Number Publication Date
HU171662B true HU171662B (hu) 1978-02-28

Family

ID=11000982

Family Applications (1)

Application Number Title Priority Date Filing Date
HU75RI00000573A HU171662B (hu) 1975-07-18 1975-07-18 Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh apovinkaminola i ikh kislotnykh adduktov

Country Status (10)

Country Link
US (1) US4108996A (hu)
JP (1) JPS5212199A (hu)
AT (1) AT350736B (hu)
BE (1) BE844229A (hu)
DE (1) DE2632118C3 (hu)
FR (1) FR2317930A1 (hu)
GB (1) GB1525640A (hu)
HU (1) HU171662B (hu)
PL (1) PL100426B1 (hu)
SE (1) SE423097B (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU177370B (en) * 1977-07-27 1981-09-28 Richter Gedeon Vegyeszet Process for producing new bracket-cross-bracket-vincaminol-esters
HU183323B (en) 1981-02-11 1984-04-28 Richter Gedeon Vegyeszet Process for producing 17,18-dihydro-apovincaminol-3-comma down comma aaove-4-comma down comma above-5-comma down comma aaove-trimethoxy-benzoate and acid additional salts thereof
HU183325B (en) * 1981-02-11 1984-04-28 Richter Gedeon Vegyeszet Process for preparing new apovincaminol-3',4',5'-trimethoxy-benzoates substituted with a nitro group
SE449863B (sv) * 1981-02-11 1987-05-25 Richter Gedeon Vegyeszet Apovinkaminolderivat, framstellning och farmaceutisk beredning derav
DE3479423D1 (en) * 1984-02-29 1989-09-21 Covex Sa Citrate of vinpocetine, and process for its preparation
HU192013B (en) * 1984-04-25 1987-04-28 Richter Gedeon Vegyeszet Process for production of new aporincavinol esther derivatives
RU2009103660A (ru) * 2006-07-07 2010-08-20 Тева Фармасьютикал Индастриес Лтд. (Il) Твердые фармацевтические композиции, включающие тадалафил и по меньшей мере один носитель
DE102007028869A1 (de) * 2007-06-22 2008-12-24 Ratiopharm Gmbh Verfahren zur Herstellung eines Arzneimittels enthaltend Tadalafil

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2035784A1 (en) * 1969-03-27 1970-12-24 Olivier Louisette Vincamine derivs with therapeutic propert- - ies
FR2108993A1 (en) 1970-10-28 1972-05-26 Forschag Vincamine alkaloid fraction - with sedative and vasoregulating effect
FR2117796A6 (en) * 1970-12-18 1972-07-28 Anvar Vincine derivs - used as antitussives, sedatives local anaesthetics and analgesics
BE790837A (fr) * 1971-11-03 1973-02-15 Richter Gedeon Vegeon Vegyesze Nouveaux esters alcaloides utiles comme vasodilatateurs cerebraux et leur procede de preparation
HU170888B (hu) * 1975-06-10 1977-09-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh eburnameninov

Also Published As

Publication number Publication date
PL100426B1 (pl) 1978-10-31
BE844229A (fr) 1976-11-16
US4108996A (en) 1978-08-22
JPS5639316B2 (hu) 1981-09-11
FR2317930B1 (hu) 1979-03-30
ATA495876A (de) 1978-11-15
DE2632118A1 (de) 1977-01-20
DE2632118C3 (de) 1979-12-13
JPS5212199A (en) 1977-01-29
SE423097B (sv) 1982-04-13
AT350736B (de) 1979-06-11
GB1525640A (en) 1978-09-20
DE2632118B2 (de) 1979-02-01
SE7608049L (sv) 1977-01-18
FR2317930A1 (fr) 1977-02-11

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee