RS20050724A - Human antibodies specific for interleukin 15(il-15) - Google Patents

Human antibodies specific for interleukin 15(il-15)

Info

Publication number
RS20050724A
RS20050724A YUP-2005/0724A YUP20050724A RS20050724A RS 20050724 A RS20050724 A RS 20050724A YU P20050724 A YUP20050724 A YU P20050724A RS 20050724 A RS20050724 A RS 20050724A
Authority
RS
Serbia
Prior art keywords
human
human antibodies
antibodies
interleukin
antibodies specific
Prior art date
Application number
YUP-2005/0724A
Other languages
English (en)
Serbian (sr)
Inventor
Jan Van De Winkel
Marcus Antonius Van Dijk
Janine Schuurman
Armout Gerritsen
Ole Baadsgaard
Jorgen Petersen
Original Assignee
Genmab A/S.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/374,932 external-priority patent/US7329405B2/en
Priority claimed from US10/379,741 external-priority patent/US7247304B2/en
Application filed by Genmab A/S., filed Critical Genmab A/S.,
Publication of RS20050724A publication Critical patent/RS20050724A/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
YUP-2005/0724A 2003-02-26 2004-02-25 Human antibodies specific for interleukin 15(il-15) RS20050724A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/374,932 US7329405B2 (en) 2001-08-23 2003-02-26 Human antibodies specific for interleukin 15 (IL-15)
US10/379,741 US7247304B2 (en) 2001-08-23 2003-03-05 Methods of treating using anti-IL-15 antibodies
PCT/IB2004/000484 WO2004076620A2 (en) 2003-02-26 2004-02-25 Human antibodies specific for interleukin 15 (il-15)

Publications (1)

Publication Number Publication Date
RS20050724A true RS20050724A (en) 2007-11-15

Family

ID=36770634

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-2005/0724A RS20050724A (en) 2003-02-26 2004-02-25 Human antibodies specific for interleukin 15(il-15)

Country Status (6)

Country Link
JP (1) JP4892335B2 (es)
CN (1) CN1780856A (es)
AR (1) AR043405A1 (es)
EA (1) EA015897B1 (es)
RS (1) RS20050724A (es)
ZA (1) ZA200506724B (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2690825C (en) 2007-05-11 2019-02-12 Altor Bioscience Corporation Fusion molecules and il-15 variants
US11053299B2 (en) 2010-09-21 2021-07-06 Immunity Bio, Inc. Superkine
KR20140020228A (ko) 2010-09-21 2014-02-18 알토 바이오사이언스 코포레이션 다량체성 아이엘 15 용해성 융합 분자 및 그의 제조 및 사용 방법
CN102250243B (zh) * 2011-07-01 2013-08-28 华绍炳 抗白细胞介素-15抗体
US9925247B2 (en) 2014-06-30 2018-03-27 Altor Bioscience Corporation IL-15-based molecules and methods of use thereof
EP2963057A1 (en) * 2014-07-02 2016-01-06 Calypso Biotech SA Antibodies to IL-15
BR112018076287A2 (pt) * 2016-06-15 2019-03-26 Amgen Inc. métodos e composições para o tratamento de doença celíaca, sensibilidade ao glúten não celíaca e doença celíaca refratária
SG11201903306SA (en) 2016-10-21 2019-05-30 Altor Bioscience Corp Multimeric il-15-based molecules
AR110414A1 (es) * 2016-12-21 2019-03-27 Cephalon Inc Anticuerpos que se unen específicamente a il-15 humana y usos de estos
US20220354097A1 (en) * 2019-12-25 2022-11-10 Gempharmatech Co., Ltd. Il-15 humanized mouse model and use thereof
CN114377133A (zh) * 2022-01-20 2022-04-22 山东大学 靶向肾脏cd8+trm形成与活化在肾小球损伤中的应用
CN115362984B (zh) * 2022-07-07 2024-01-16 成都中医药大学 一种小鼠自身免疫性甲状腺炎模型的构建方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795966A (en) * 1995-02-22 1998-08-18 Immunex Corp Antagonists of interleukin-15
GB9814892D0 (en) * 1998-07-10 1998-09-09 Kennedy Rheumatology Inst Treatment of celiac disease
AU6689700A (en) * 1999-07-06 2001-01-22 Silvia Bulfone-Paus Method of treating psoriasis with il-15 antagonist
AU2002332628B2 (en) * 2001-08-23 2007-07-26 Genmab A/S Human antibodies specific for interleukin 15 (IL-15)

Also Published As

Publication number Publication date
JP4892335B2 (ja) 2012-03-07
EA015897B1 (ru) 2011-12-30
CN1780856A (zh) 2006-05-31
AR043405A1 (es) 2005-07-27
ZA200506724B (en) 2007-03-28
EA200501362A1 (ru) 2006-02-24
JP2007528348A (ja) 2007-10-11

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