RO69912A - Procede pour la preparation des tieno(1,5) benzodiazepines - Google Patents

Procede pour la preparation des tieno(1,5) benzodiazepines

Info

Publication number
RO69912A
RO69912A RO7584018A RO8401875A RO69912A RO 69912 A RO69912 A RO 69912A RO 7584018 A RO7584018 A RO 7584018A RO 8401875 A RO8401875 A RO 8401875A RO 69912 A RO69912 A RO 69912A
Authority
RO
Romania
Prior art keywords
tieno
benzodiazepines
preparation
Prior art date
Application number
RO7584018A
Other languages
English (en)
Romanian (ro)
Inventor
Jiban K Chakrabarti
David E Tupper
Original Assignee
Lilly Industries Ltd,Gb
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10459213&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RO69912(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Industries Ltd,Gb filed Critical Lilly Industries Ltd,Gb
Publication of RO69912A publication Critical patent/RO69912A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RO7584018A 1974-11-26 1975-11-25 Procede pour la preparation des tieno(1,5) benzodiazepines RO69912A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB51240/74A GB1533235A (en) 1974-11-26 1974-11-26 Benzodiazepine derivatives

Publications (1)

Publication Number Publication Date
RO69912A true RO69912A (fr) 1980-08-15

Family

ID=10459213

Family Applications (1)

Application Number Title Priority Date Filing Date
RO7584018A RO69912A (fr) 1974-11-26 1975-11-25 Procede pour la preparation des tieno(1,5) benzodiazepines

Country Status (30)

Country Link
JP (1) JPS6044314B2 (fr)
AR (1) AR221203A1 (fr)
AT (1) AT351547B (fr)
AU (1) AU506340B2 (fr)
BE (1) BE835932A (fr)
BG (1) BG29573A3 (fr)
CA (1) CA1075687A (fr)
CH (2) CH613455A5 (fr)
CS (1) CS236753B2 (fr)
DD (1) DD123343A5 (fr)
DE (1) DE2552403C2 (fr)
DK (1) DK146887C (fr)
ES (1) ES443011A1 (fr)
FR (1) FR2292479A1 (fr)
GB (1) GB1533235A (fr)
HK (1) HK58681A (fr)
HU (1) HU172493B (fr)
IE (1) IE42564B1 (fr)
IL (1) IL48502A (fr)
KE (1) KE3163A (fr)
MY (1) MY8200149A (fr)
NL (1) NL186088C (fr)
NZ (1) NZ179335A (fr)
PH (2) PH11669A (fr)
PL (1) PL100135B1 (fr)
RO (1) RO69912A (fr)
SE (2) SE421209B (fr)
SU (2) SU629879A3 (fr)
YU (1) YU298375A (fr)
ZA (1) ZA757344B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
GB8819059D0 (en) * 1988-08-11 1988-09-14 Lilly Industries Ltd Benzodiazepine compounds & their use as pharmaceuticals
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
PT582368E (pt) * 1992-05-29 2001-05-31 Lilly Co Eli Derivados de tienobenzodiazepina para o tratamento de doencas de cns
US6043358A (en) 1995-11-01 2000-03-28 Merck & Co., Inc. Hexahydro-5-imino-1,4-heteroazepine derivatives as inhibitors of nitric oxide synthases
JP3188715B2 (ja) * 1995-11-01 2001-07-16 メルク エンド カンパニー インコーポレーテッド 一酸化窒素シンターゼの阻害物質としてのヘキサヒドロ−5−イミノ−1,4−ヘテロアゼピン誘導体
WO1999011647A1 (fr) 1997-09-02 1999-03-11 Yoshitomi Pharmaceutical Industries, Ltd. Composes thiophene condenses et leur utilisation en medecine
PL199016B1 (pl) * 2002-06-20 2008-08-29 Adamed Sp Z Oo Sposób wytwarzania olanzapiny
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
DE10301923B3 (de) * 2003-01-17 2004-09-16 Krka Tovarna Zdravil, D.D. Verfahren und Zwischenprodukte zur Herstellung von Olanzapin
AR047461A1 (es) * 2004-01-27 2006-01-18 Synthon Bv Formacion, purificacion y uso de n-formilolanzapina
AR048272A1 (es) 2004-03-18 2006-04-12 Lek Pharmaceuticals Sintesis de 2 metil - 4- (4- metil -1- piperazinil) - 10 h- tieno ( 2,3-b) (1,5) benzodiazepina y sus sales, metodos para su preparacion, composiciones farmaceuticas que la contienen y su uso en la fabricacion de medicamentos para el tratamiento de enfermedades mentales.
CA2565683C (fr) * 2004-06-30 2013-04-02 Athersys, Inc. Derives d'azepine substitues utilises comme modulateurs des recepteurs de la serotonine
EP2292624A1 (fr) 2009-07-20 2011-03-09 LEK Pharmaceuticals d.d. Processus de purification d'olanzapine

Also Published As

Publication number Publication date
BG29573A3 (en) 1980-12-12
HU172493B (hu) 1978-09-28
SE7812194L (sv) 1978-11-27
DD123343A5 (fr) 1976-12-12
AU8685875A (en) 1977-05-26
CH613454A5 (en) 1979-09-28
NZ179335A (en) 1978-11-13
IL48502A (en) 1980-01-31
DE2552403C2 (de) 1986-06-19
DK524175A (da) 1976-05-27
AT351547B (de) 1979-07-25
JPS5176296A (en) 1976-07-01
ZA757344B (en) 1976-11-24
DK146887C (da) 1984-07-09
SU626702A3 (ru) 1978-09-30
CS236753B2 (en) 1985-05-15
SE429045B (sv) 1983-08-08
IE42564L (en) 1976-05-26
KE3163A (en) 1981-10-16
FR2292479A1 (fr) 1976-06-25
CH613455A5 (en) 1979-09-28
DK146887B (da) 1984-01-30
PH24534A (en) 1990-08-03
ES443011A1 (es) 1977-07-01
JPS6044314B2 (ja) 1985-10-02
SU629879A3 (ru) 1978-10-25
AU506340B2 (en) 1979-12-20
IE42564B1 (en) 1980-09-10
IL48502A0 (en) 1976-01-30
CA1075687A (fr) 1980-04-15
HK58681A (en) 1981-12-04
MY8200149A (en) 1982-12-31
PL100135B1 (pl) 1978-09-30
NL186088C (nl) 1990-09-17
BE835932A (fr) 1976-05-25
YU298375A (en) 1982-10-31
ATA898275A (de) 1979-01-15
SE7513185L (sv) 1976-05-27
PH11669A (en) 1978-05-19
SE421209B (sv) 1981-12-07
AR221203A1 (es) 1981-01-15
NL7513833A (nl) 1976-05-31
DE2552403A1 (de) 1976-08-12
FR2292479B1 (fr) 1978-07-28
NL186088B (nl) 1990-04-17
GB1533235A (en) 1978-11-22

Similar Documents

Publication Publication Date Title
RO72736A (fr) Procede pour la preparation des 2-tetrahydrofurfuryle-6,7-benzomorphanes-5,9-beta-disubstitus
RO70051A (fr) Procede pour la preparation des 2-tetra-hydrofurfurile-6,7-benzomorphanes
RO68142A (fr) Procede pour la preparation des 4-phenylpyperidines
RO65454A (fr) Procede pour la preparation des calcones substituees
RO69608A (fr) Procede pour la preparation des 1,2-benzisothiazole-3-ones
RO69912A (fr) Procede pour la preparation des tieno(1,5) benzodiazepines
RO68145A (fr) Procede pour la preparation des 3,4-dihydro-2h-1,2-benzothiazincarboxamides
BE838823A (fr) Procede pour la preparation de 1,2,5-dihydroxycholecalciferol
RO66914A (fr) Procede pour la preparation des pyrido-benzodiazepinones
RO64606A (fr) Procede pour la preparation des 6-methylergolines-8,8-disubstituees
RO67193A (fr) Procede pour la preparation du 2,2,6,6-tetramethyle-4-piperydone
RO63021A (fr) Procede pour la preparation des 3-fluorcephalosporines
RO64281A (fr) Procede pour la preparation des 6-methyle-8-methylergolines substituees
RO76667A (fr) Procede pour la preparation des 2,4-dialkyamino-6-chlore-5-triazines
FR2303798A1 (fr) Procede pour la preparation de (3r, 3'r)-zeaxanthene
RO68749A (fr) Procede pour la preparation des 2-amidoimidazoles
BE826343A (fr) Procede de preparation de s-triazolo(3,4- bbenzothiazoles
RO66020A (fr) Procede pour la preparation des 3-pyperazinoisoquinolines
RO70232A (fr) Procede pour la preparation des 4-pyrazolile-4h-1,2,4-triazolile
RO72516A (fr) Procede pour la preparation des quinoxalin-1,4-dioxydes
BE809494A (fr) Procede pour la preparation de 1,4-dioxanne
RO68650A (fr) Procede pour la preparation des imidazole-(1,2-a)-procede pour la preparation des imidazole-(1,2-a)ss-triazines -triazines
BE835855A (fr) Procede de preparation de nouvelles 7,7 -diphenyl - hexahydro - 1,4 - oxazepines
BE833733A (fr) Procede pour la preparation d'agglomeres
FR2283150A1 (fr) Procede pour la preparation d'hydroxy-11b alkyl-18 oestranes