PT96411A - Processo para a preparacao de derivados de azaoxindole - Google Patents

Processo para a preparacao de derivados de azaoxindole

Info

Publication number
PT96411A
PT96411A PT96411A PT9641191A PT96411A PT 96411 A PT96411 A PT 96411A PT 96411 A PT96411 A PT 96411A PT 9641191 A PT9641191 A PT 9641191A PT 96411 A PT96411 A PT 96411A
Authority
PT
Portugal
Prior art keywords
preparing
azaoxindole
derivatives
azaoxindole derivatives
preparing azaoxindole
Prior art date
Application number
PT96411A
Other languages
English (en)
Other versions
PT96411B (pt
Inventor
Ralph P Robinson
Anthony Marfat
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT96411A publication Critical patent/PT96411A/pt
Publication of PT96411B publication Critical patent/PT96411B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT96411A 1990-01-05 1991-01-03 Processo para a preparacao de derivados de azaoxindole PT96411B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1990/000107 WO1991009598A1 (en) 1990-01-05 1990-01-05 Azaoxindole derivatives

Publications (2)

Publication Number Publication Date
PT96411A true PT96411A (pt) 1991-10-15
PT96411B PT96411B (pt) 1999-04-30

Family

ID=22220612

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96411A PT96411B (pt) 1990-01-05 1991-01-03 Processo para a preparacao de derivados de azaoxindole

Country Status (19)

Country Link
EP (1) EP0436333A3 (pt)
JP (1) JPH0826018B2 (pt)
KR (1) KR930005447B1 (pt)
CN (1) CN1031053C (pt)
AU (1) AU635593B2 (pt)
BR (1) BR9100046A (pt)
CA (1) CA2033531C (pt)
CS (1) CS991A2 (pt)
FI (1) FI922347A (pt)
IE (1) IE910022A1 (pt)
IL (1) IL96819A0 (pt)
MY (1) MY109722A (pt)
NO (1) NO922634L (pt)
NZ (1) NZ236582A (pt)
PL (2) PL165653B1 (pt)
PT (1) PT96411B (pt)
WO (1) WO1991009598A1 (pt)
YU (1) YU47728B (pt)
ZA (1) ZA9172B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL101860A0 (en) * 1991-05-31 1992-12-30 Ici Plc Heterocyclic derivatives
GB9226855D0 (en) * 1992-12-23 1993-02-17 Erba Carlo Spa Vinylene-azaindole derivatives and process for their preparation
FR2722195B1 (fr) * 1994-07-07 1996-08-23 Adir Nouveaux derives de 1,3-dihydro-2h-pyrrolo(2,3-b) pyridin-2-ones et oxazolo(4,5-b) pyridin-2(3h)-ones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5618819A (en) * 1994-07-07 1997-04-08 Adir Et Compagnie 1,3-dihydro-2H-pyrrolo[2,3-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-(3H)-one compounds
FR2722196B1 (fr) * 1994-07-07 1996-08-23 Adir Nouveaux derives amines de 1,3-dihydro-2h-pyrrolo(2,3-b) pyridin-2-ones et oxazolo(4,5-b) pyridin-2 (3h)-ones, leur procede de preparation et les compositions pharmaceutique qui les contiennent
US5939069A (en) 1996-08-23 1999-08-17 University Of Florida Materials and methods for detection and treatment of immune system dysfunctions
GB9718913D0 (en) 1997-09-05 1997-11-12 Glaxo Group Ltd Substituted oxindole derivatives
PT1157019E (pt) * 1998-12-17 2003-06-30 Hoffmann La Roche 4-alcenil (e alcinil) oxindolos como inibidores dequinases dependentes de ciclina em particular cdk2
KR20010101266A (ko) 1998-12-17 2001-11-14 프리돌린 클라우스너, 롤란드 비. 보레르 Ｊｎｋ 단백질 키나제의 억제제로서의 4-아릴옥신돌
AU767138B2 (en) 1998-12-17 2003-10-30 F. Hoffmann-La Roche Ag 4,5-pyrazinoxindoles as protein kinase inhibitors
US6153634A (en) 1998-12-17 2000-11-28 Hoffmann-La Roche Inc. 4,5-azolo-oxindoles
US6624171B1 (en) 1999-03-04 2003-09-23 Smithkline Beecham Corporation Substituted aza-oxindole derivatives
GB9904933D0 (en) 1999-03-04 1999-04-28 Glaxo Group Ltd Compounds
US6492398B1 (en) 1999-03-04 2002-12-10 Smithkline Beechman Corporation Thiazoloindolinone compounds
US6313310B1 (en) 1999-12-15 2001-11-06 Hoffmann-La Roche Inc. 4-and 5-alkynyloxindoles and 4-and 5-alkenyloxindoles
EP1244672B1 (en) 1999-12-21 2005-07-20 Sugen, Inc. 4-substituted 7-aza-indolin-2-ones and their use as protein kinase inhibitors
US6620818B1 (en) 2000-03-01 2003-09-16 Smithkline Beecham Corporation Method for reducing the severity of side effects of chemotherapy and/or radiation therapy
DE10053275A1 (de) * 2000-10-27 2002-05-02 Dresden Arzneimittel Neue 7-Azaindole, deren Verwendung als Inhibitoren der Phosphodiesterase 4 und Verfahren zu deren Herstellung
TWI262920B (en) 2000-10-27 2006-10-01 Elbion Ag New 7-azaindoles, their use as inhibitors of phosphodiesterase 4, and a method for synthesizing them
US7186745B2 (en) 2001-03-06 2007-03-06 Astrazeneca Ab Indolone derivatives having vascular damaging activity
JP2005534619A (ja) * 2002-03-28 2005-11-17 エーザイ株式会社 Ｃ−ｊｕｎｎ−末端キナーゼ阻害剤としてのアザインドール
WO2005121140A1 (en) 2004-06-09 2005-12-22 Glaxo Group Limited Pyrrolopyridine derivatives
WO2006042102A2 (en) * 2004-10-05 2006-04-20 Neurogen Corporation Pyrrolo-pyridine, pyrrolo-pyrimidine and related heterocyclic compounds
WO2009147476A1 (en) * 2008-06-02 2009-12-10 Matrix Laboratories Ltd. Novel pde inhibitors, pharmaceutical compositions containing them and processes for their preparation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4556672A (en) * 1984-03-19 1985-12-03 Pfizer Inc. 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents
US4569942A (en) * 1984-05-04 1986-02-11 Pfizer Inc. N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents
ATE67185T1 (de) * 1985-07-09 1991-09-15 Pfizer Substituierte oxindol-3-carboxamine als entzuendungshemmendes und schmerzstillendes mittel.
AU3776589A (en) * 1988-06-14 1990-01-12 Schering Corporation Heterobicyclic compounds having antiinflammatory activity

Also Published As

Publication number Publication date
FI922347A0 (fi) 1992-05-22
NO922634D0 (no) 1992-07-03
YU791A (sh) 1994-01-20
WO1991009598A1 (en) 1991-07-11
PL288598A1 (en) 1991-12-02
BR9100046A (pt) 1991-10-22
YU47728B (sh) 1996-01-08
PT96411B (pt) 1999-04-30
ZA9172B (en) 1992-10-28
NZ236582A (en) 1993-10-26
FI922347A (fi) 1992-05-22
AU635593B2 (en) 1993-03-25
IL96819A0 (en) 1991-09-16
KR930005447B1 (ko) 1993-06-22
JPH04210981A (ja) 1992-08-03
CA2033531A1 (en) 1991-07-06
CS991A2 (en) 1991-09-15
PL166512B1 (pl) 1995-05-31
IE910022A1 (en) 1991-07-17
KR910014375A (ko) 1991-08-31
EP0436333A3 (en) 1992-05-27
EP0436333A2 (en) 1991-07-10
CN1031053C (zh) 1996-02-21
CA2033531C (en) 1998-06-23
PL165653B1 (pl) 1995-01-31
MY109722A (en) 1997-05-31
AU6860691A (en) 1992-03-05
JPH0826018B2 (ja) 1996-03-13
NO922634L (no) 1992-07-03
CN1053065A (zh) 1991-07-17

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910531

FG3A Patent granted, date of granting

Effective date: 19990127

MM3A Annulment or lapse

Effective date: 20060727