PT92728A - Processo para a preparacao de derivados de piperazinilo e de composicoes farmaceuticas que os contem - Google Patents

Processo para a preparacao de derivados de piperazinilo e de composicoes farmaceuticas que os contem

Info

Publication number
PT92728A
PT92728A PT92728A PT9272889A PT92728A PT 92728 A PT92728 A PT 92728A PT 92728 A PT92728 A PT 92728A PT 9272889 A PT9272889 A PT 9272889A PT 92728 A PT92728 A PT 92728A
Authority
PT
Portugal
Prior art keywords
pharmaceutical compositions
compositions containing
compounds
preparation
piperazinyl derivatives
Prior art date
Application number
PT92728A
Other languages
English (en)
Other versions
PT92728B (pt
Inventor
Jens Perregaard
John Willie Stenberg
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of PT92728A publication Critical patent/PT92728A/pt
Publication of PT92728B publication Critical patent/PT92728B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PT92728A 1988-12-28 1989-12-27 Processo para a preparacao de derivados de piperazinilo e de composicoes farmaceuticas que os contem PT92728B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888830312A GB8830312D0 (en) 1988-12-28 1988-12-28 Heterocyclic compounds

Publications (2)

Publication Number Publication Date
PT92728A true PT92728A (pt) 1990-06-29
PT92728B PT92728B (pt) 1995-12-29

Family

ID=10649223

Family Applications (1)

Application Number Title Priority Date Filing Date
PT92728A PT92728B (pt) 1988-12-28 1989-12-27 Processo para a preparacao de derivados de piperazinilo e de composicoes farmaceuticas que os contem

Country Status (17)

Country Link
US (1) US5002948A (pt)
EP (1) EP0376607B1 (pt)
JP (1) JP2895121B2 (pt)
AT (1) ATE102184T1 (pt)
AU (1) AU637991B2 (pt)
CA (1) CA2006356C (pt)
DE (1) DE68913487T2 (pt)
DK (1) DK169266B1 (pt)
ES (1) ES2062050T3 (pt)
FI (1) FI93005C (pt)
GB (1) GB8830312D0 (pt)
IE (1) IE62668B1 (pt)
IL (1) IL92990A (pt)
NO (1) NO174772C (pt)
NZ (1) NZ231855A (pt)
PT (1) PT92728B (pt)
ZA (1) ZA899960B (pt)

Families Citing this family (82)

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DE3923045A1 (de) * 1989-07-13 1991-01-17 Merck Patent Gmbh Indolderivate
DE69123090D1 (de) * 1990-07-06 1996-12-19 Yoshitomi Pharmaceutical Kondensierte Thiophenverbindungen und deren Verwendung
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
FR2670491B1 (fr) * 1990-12-14 1993-02-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant.
DE4101686A1 (de) * 1991-01-22 1992-07-23 Merck Patent Gmbh Indolderivate
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
DE4127849A1 (de) * 1991-08-22 1993-02-25 Merck Patent Gmbh Benzodioxanderivate
CA2084531A1 (en) * 1991-12-19 1993-06-20 David W. Smith Antimigraine 4-pyrimidinyl and pyridinyl derivatives of indol-3yl-alkyl piperazines
DK55192D0 (da) * 1992-04-28 1992-04-28 Lundbeck & Co As H 1-piperazino-1,2-dihydroindenderivater
FR2692264B1 (fr) * 1992-06-12 1994-08-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les contenant.
DK78692D0 (da) * 1992-06-12 1992-06-12 Lundbeck & Co As H Dimere piperidin- og piperazinderivater
ES2050623B1 (es) * 1992-11-06 1994-12-16 Merck Patent Gmbh Derivados de 1,4-benzodioxano.
DK148392D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocykliske forbindelser
WO1994014769A1 (en) * 1992-12-21 1994-07-07 Taisho Pharmaceutical Co., Ltd. N-substituted indole derivative
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RU2118322C1 (ru) * 1993-07-05 1998-08-27 Дюфар Интернэшнл Рисерч Б.В. 2,3-дигидро-1,4-бензодиокси-5-ил-пиперазиновые производные или их соли
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AR013206A1 (es) * 1997-07-25 2000-12-13 Lundbeck & Co As H Derivados indol y 2,3-dihidroindol, composiciones farmaceuticas que contienen estos compuestos y el uso de dichos compuestos para la preparacion de un medicamento para el tratamiento de desordenes sensibles a la inhibicion de la reabsorcion de serotonina y antagonismo de receptores 5-ht1a.
DE69819173T2 (de) * 1997-07-25 2004-04-15 H. Lundbeck A/S Indole und 2,3-dihydroindolderivate, ihre herstellung und verwendung
CA2327303A1 (en) * 1998-04-08 1999-10-14 American Home Products Corporation N-aryloxyethylamine derivatives for the treatment of depression
AR022303A1 (es) 1999-01-22 2002-09-04 Lundbeck & Co As H Derivados de piperidina, tetrahidropiridina y piperazina, su preparacion y utilizacion
KR100634039B1 (ko) * 1999-08-23 2006-10-17 솔베이 파마슈티칼스 비. 브이 신규한 페닐피페라진
IL150337A0 (en) * 1999-12-30 2002-12-01 Lundbeck & Co As H Phenylpiperazinyl derivatives
AR027134A1 (es) * 1999-12-30 2003-03-12 Lundbeck & Co As H Derivados de indol.
UA72948C2 (uk) * 1999-12-30 2005-05-16 Х. Луннбек А/С Заміщені похідні фенілпіперазину, фармацевтична композиція та спосіб лікування афективних або неврологічних захворювань і розладів
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AR032712A1 (es) 2001-02-21 2003-11-19 Solvay Pharm Bv Un mesilato de derivados de fenilpiperazina y composiciones farmaceuticas que lo contienen
US7041683B2 (en) 2001-04-24 2006-05-09 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 2,3-dihydro-1, 4-benzodiozan
US6559169B2 (en) 2001-04-24 2003-05-06 Wyeth Antidepressant azaheterocyclymethyl derivatives of 2,3-dihydro-1,4-benzodioxan
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CN102574787B (zh) * 2009-07-30 2014-12-31 新加坡国立大学 具有潜在的抗癌活性的小分子异戊二烯基半胱氨酸羧基甲基转移酶抑制剂
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CN106065018B (zh) * 2015-04-23 2020-04-21 广东东阳光药业有限公司 取代的吲哚化合物及其使用方法和用途
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Also Published As

Publication number Publication date
NZ231855A (en) 1992-02-25
GB8830312D0 (en) 1989-02-22
DK645689A (da) 1990-06-29
ES2062050T3 (es) 1994-12-16
IL92990A0 (en) 1990-09-17
DE68913487D1 (de) 1994-04-07
CA2006356C (en) 1999-09-14
NO895281L (no) 1990-06-29
DE68913487T2 (de) 1994-08-04
DK645689D0 (da) 1989-12-19
IE62668B1 (en) 1995-02-22
FI896300A0 (fi) 1989-12-28
US5002948A (en) 1991-03-26
CA2006356A1 (en) 1990-06-28
EP0376607B1 (en) 1994-03-02
EP0376607A1 (en) 1990-07-04
NO174772C (no) 1994-07-06
FI93005B (fi) 1994-10-31
JP2895121B2 (ja) 1999-05-24
PT92728B (pt) 1995-12-29
DK169266B1 (da) 1994-09-26
ZA899960B (en) 1990-11-28
NO174772B (no) 1994-03-28
IE893976L (en) 1990-06-13
IL92990A (en) 1995-01-24
FI93005C (fi) 1995-02-10
JPH02225460A (ja) 1990-09-07
ATE102184T1 (de) 1994-03-15
AU637991B2 (en) 1993-06-17
NO895281D0 (no) 1989-12-27
AU4719889A (en) 1990-07-05

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