PT2508521E - Dimaleato de um composto de aminocrotonilo e processo para a sua preparação - Google Patents
Dimaleato de um composto de aminocrotonilo e processo para a sua preparação Download PDFInfo
- Publication number
- PT2508521E PT2508521E PT121556625T PT12155662T PT2508521E PT 2508521 E PT2508521 E PT 2508521E PT 121556625 T PT121556625 T PT 121556625T PT 12155662 T PT12155662 T PT 12155662T PT 2508521 E PT2508521 E PT 2508521E
- Authority
- PT
- Portugal
- Prior art keywords
- dimaleat
- production
- compound
- amino
- amino crotonyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10349113A DE10349113A1 (de) | 2003-10-17 | 2003-10-17 | Verfahren zur Herstellung von Aminocrotonylverbindungen |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2508521E true PT2508521E (pt) | 2016-03-31 |
Family
ID=34428508
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT47659271T PT1678165E (pt) | 2003-10-17 | 2004-10-12 | Processo para a preparação de compostos de aminocrotonilo |
PT121556625T PT2508521E (pt) | 2003-10-17 | 2004-10-12 | Dimaleato de um composto de aminocrotonilo e processo para a sua preparação |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT47659271T PT1678165E (pt) | 2003-10-17 | 2004-10-12 | Processo para a preparação de compostos de aminocrotonilo |
Country Status (35)
Country | Link |
---|---|
US (2) | US20050085495A1 (pt) |
EP (2) | EP2508521B2 (pt) |
JP (2) | JP4594317B2 (pt) |
KR (2) | KR101282812B1 (pt) |
CN (2) | CN101402631A (pt) |
AR (1) | AR046118A1 (pt) |
AU (2) | AU2004281938B2 (pt) |
BR (2) | BRPI0415424B8 (pt) |
CA (2) | CA2759063C (pt) |
CY (2) | CY1114866T1 (pt) |
DE (1) | DE10349113A1 (pt) |
DK (2) | DK1678165T3 (pt) |
EA (1) | EA016624B1 (pt) |
EC (1) | ECSP066509A (pt) |
ES (2) | ES2440466T3 (pt) |
HK (1) | HK1095817A1 (pt) |
HR (2) | HRP20160246T4 (pt) |
HU (1) | HUE028254T2 (pt) |
IL (2) | IL174951A (pt) |
ME (1) | ME00341B (pt) |
MX (2) | MXPA06004076A (pt) |
MY (2) | MY155425A (pt) |
NO (2) | NO333971B1 (pt) |
NZ (2) | NZ583049A (pt) |
PE (2) | PE20050965A1 (pt) |
PL (2) | PL2508521T5 (pt) |
PT (2) | PT1678165E (pt) |
RS (3) | RS60563B1 (pt) |
SG (1) | SG139743A1 (pt) |
SI (2) | SI2508521T2 (pt) |
TW (2) | TWI348468B (pt) |
UA (2) | UA91006C2 (pt) |
UY (2) | UY28559A1 (pt) |
WO (1) | WO2005037824A2 (pt) |
ZA (1) | ZA200602234B (pt) |
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SK287010B6 (sk) | 1999-06-21 | 2009-09-07 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Bicyklické heterocyklické zlúčeniny, spôsob ich prípravy, farmaceutický prostriedok s ich obsahom a ich použitie |
US7019012B2 (en) * | 2000-12-20 | 2006-03-28 | Boehringer Ingelheim International Pharma Gmbh & Co. Kg | Quinazoline derivatives and pharmaceutical compositions containing them |
DE10221018A1 (de) * | 2002-05-11 | 2003-11-27 | Boehringer Ingelheim Pharma | Verwendung von Hemmern der EGFR-vermittelten Signaltransduktion zur Behandlung von gutartiger Prostatahyperplasie (BPH)/Prostatahypertrophie |
US20050043233A1 (en) * | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
DE10349113A1 (de) * | 2003-10-17 | 2005-05-12 | Boehringer Ingelheim Pharma | Verfahren zur Herstellung von Aminocrotonylverbindungen |
KR100832594B1 (ko) * | 2005-11-08 | 2008-05-27 | 한미약품 주식회사 | 다중저해제로서의 퀴나졸린 유도체 및 이의 제조방법 |
PL1948180T3 (pl) | 2005-11-11 | 2013-09-30 | Boehringer Ingelheim Int | Terapia skojarzona raka polegająca na podawaniu inhibitorów EGFR/HER2 |
WO2007054550A1 (en) * | 2005-11-11 | 2007-05-18 | Boehringer Ingelheim International Gmbh | Quinazoline derivatives for the treatment of cancer diseases |
CA2639936C (en) * | 2006-01-26 | 2014-06-17 | Boehringer Ingelheim International Gmbh | Process for preparing aminocrotonylamino-substituted quinazoline derivatives |
BRPI0717586A2 (pt) | 2006-09-18 | 2013-10-29 | Boehringer Ingelheim Int | Método para tratar câncer apresentando mutações do egfr |
PE20100252A1 (es) * | 2008-06-06 | 2010-04-12 | Boehringer Ingelheim Int | Nuevas formulaciones farmaceuticas solidas que comprenden dimaleato de 4-[(3-cloro-4-fluorofenil) amino]-6-{[4-(n,n-dimetilamino)-1-oxo-2-buten-1-il] amino}-7-((s)-tetrahidrofuran-3-iloxi)-quinazolina |
WO2010081817A1 (en) | 2009-01-14 | 2010-07-22 | Boehringer Ingelheim International Gmbh | Method for treating colorectal cancer |
CN105541836A (zh) | 2009-03-11 | 2016-05-04 | 奥克兰联合服务有限公司 | 激酶抑制剂的前药形式及其在治疗中的用途 |
WO2010130757A1 (en) | 2009-05-14 | 2010-11-18 | Boehringer Ingelheim International Gmbh | New combination therapy in treatment of oncological and fibrotic diseases |
CA2804190A1 (en) * | 2009-07-02 | 2011-01-06 | Newgen Therapeutics, Inc. | Phosphorus containing quinazoline compounds and methods of use |
WO2011003853A2 (en) | 2009-07-06 | 2011-01-13 | Boehringer Ingelheim International Gmbh | Process for drying of bibw2992, of its salts and of solid pharmaceutical formulations comprising this active ingredient |
JP2013512882A (ja) | 2009-12-07 | 2013-04-18 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | トリプルネガティブ乳癌の治療に使用するbibw2992 |
US20120107304A1 (en) * | 2010-04-27 | 2012-05-03 | Boehringer Ingelheim International Gmbh | Combination therapy in treatment of oncological and fibrotic diseases |
PL2608792T3 (pl) | 2010-08-26 | 2018-03-30 | Boehringer Ingelheim International Gmbh | Sposoby podawania inhibitora EGFR |
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KR20210106157A (ko) | 2020-02-20 | 2021-08-30 | 서울대학교산학협력단 | 알로페론을 포함하는 난소암 치료용 조성물 및 치료 보조제 |
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