PL3534885T3 - Inhibitory farnezylotransferazy do zastosowania w leczeniu nowotworu - Google Patents

Inhibitory farnezylotransferazy do zastosowania w leczeniu nowotworu

Info

Publication number
PL3534885T3
PL3534885T3 PL17842428T PL17842428T PL3534885T3 PL 3534885 T3 PL3534885 T3 PL 3534885T3 PL 17842428 T PL17842428 T PL 17842428T PL 17842428 T PL17842428 T PL 17842428T PL 3534885 T3 PL3534885 T3 PL 3534885T3
Authority
PL
Poland
Prior art keywords
treating cancer
farnesyltransferase inhibitors
farnesyltransferase
inhibitors
cancer
Prior art date
Application number
PL17842428T
Other languages
English (en)
Inventor
Antonio Gualberto
Catherine Rose Scholz
Original Assignee
Kura Oncology, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kura Oncology, Inc. filed Critical Kura Oncology, Inc.
Publication of PL3534885T3 publication Critical patent/PL3534885T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2531/00—Reactions of nucleic acids characterised by
    • C12Q2531/10—Reactions of nucleic acids characterised by the purpose being amplify/increase the copy number of target nucleic acid
    • C12Q2531/113—PCR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
PL17842428T 2016-11-03 2017-11-02 Inhibitory farnezylotransferazy do zastosowania w leczeniu nowotworu PL3534885T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662417044P 2016-11-03 2016-11-03
PCT/US2017/059686 WO2018085518A2 (en) 2016-11-03 2017-11-02 Methods of treating cancer patients with farnesyltransferase inhibitors
EP17842428.9A EP3534885B1 (en) 2016-11-03 2017-11-02 Farnesyltransferase inhibitors for use in treating cancer

Publications (1)

Publication Number Publication Date
PL3534885T3 true PL3534885T3 (pl) 2021-11-15

Family

ID=61249690

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17842428T PL3534885T3 (pl) 2016-11-03 2017-11-02 Inhibitory farnezylotransferazy do zastosowania w leczeniu nowotworu

Country Status (26)

Country Link
US (2) US11124839B2 (pl)
EP (2) EP3838275A1 (pl)
JP (1) JP2019534290A (pl)
KR (1) KR20190082247A (pl)
CN (1) CN110325212B (pl)
AR (1) AR110031A1 (pl)
AU (1) AU2017353838A1 (pl)
BR (1) BR112019009000A2 (pl)
CA (1) CA3042747A1 (pl)
DK (1) DK3534885T3 (pl)
EA (1) EA201991091A1 (pl)
ES (1) ES2863730T3 (pl)
HR (1) HRP20210544T1 (pl)
HU (1) HUE053927T2 (pl)
IL (1) IL266182A (pl)
LT (1) LT3534885T (pl)
MX (1) MX2019005065A (pl)
MY (1) MY190861A (pl)
PH (1) PH12019500927A1 (pl)
PL (1) PL3534885T3 (pl)
PT (1) PT3534885T (pl)
RS (1) RS61745B1 (pl)
SG (1) SG11201903786UA (pl)
SI (1) SI3534885T1 (pl)
TW (1) TW201818965A (pl)
WO (1) WO2018085518A2 (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3640345T (pt) 2015-08-17 2021-12-29 Kura Oncology Inc Métodos de tratamento de doentes com cancro usando inibidores da farnesiltransferase
MX2019005065A (es) 2016-11-03 2019-08-21 Kura Oncology Inc Metodos de tratamiento de pacientes con cancer con inhibidores de farnesiltransferasa.
TW202016316A (zh) * 2018-06-19 2020-05-01 日商武田藥品工業股份有限公司 癌症治療方法
EP3873469A2 (en) * 2018-11-01 2021-09-08 Kura Oncology, Inc. Methods of treating cancer with farnesyltransferase inhibitors
AU2019403379A1 (en) * 2018-12-21 2021-07-15 Kura Oncology, Inc. Therapies for squamous cell carcinomas
SG11202110472WA (en) * 2019-03-29 2021-10-28 Kura Oncology Inc Methods of treating squamous cell carcinomas with farnesyltransferase inhibitors
US20220401436A1 (en) * 2019-11-08 2022-12-22 INSERM (Institute National de la Santé et de la Recherche Médicale) Methods for the treatment of cancers that have acquired resistance to kinase inhibitors

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BR112019009000A2 (pt) 2019-07-16
CN110325212B (zh) 2022-03-22
CN110325212A (zh) 2019-10-11
HUE053927T2 (hu) 2021-07-28
EA201991091A1 (ru) 2019-11-29
EP3838275A1 (en) 2021-06-23
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US20180187266A1 (en) 2018-07-05
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US20210381063A1 (en) 2021-12-09
PT3534885T (pt) 2021-04-13
SI3534885T1 (sl) 2021-08-31
HRP20210544T1 (hr) 2021-08-20
EP3534885B1 (en) 2021-01-20
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