PH25056A - 4,5,6-substituted-n-(substituted-phenyl)-2-pyrimidinamines - Google Patents
4,5,6-substituted-n-(substituted-phenyl)-2-pyrimidinaminesInfo
- Publication number
- PH25056A PH25056A PH34715A PH34715A PH25056A PH 25056 A PH25056 A PH 25056A PH 34715 A PH34715 A PH 34715A PH 34715 A PH34715 A PH 34715A PH 25056 A PH25056 A PH 25056A
- Authority
- PH
- Philippines
- Prior art keywords
- substituted
- pyrimidinamines
- phenyl
- disclosure describes
- describes novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Photoreceptors In Electrophotography (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81795186A | 1986-01-13 | 1986-01-13 |
Publications (1)
Publication Number | Publication Date |
---|---|
PH25056A true PH25056A (en) | 1991-01-28 |
Family
ID=25224278
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH34715A PH25056A (en) | 1986-01-13 | 1987-01-13 | 4,5,6-substituted-n-(substituted-phenyl)-2-pyrimidinamines |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0233461B2 (de) |
JP (1) | JPH0780857B2 (de) |
KR (1) | KR900004693B1 (de) |
AT (1) | ATE135699T1 (de) |
AU (2) | AU591223B2 (de) |
BR (1) | BR1100989A (de) |
CA (1) | CA1320201C (de) |
DE (1) | DE3751742T3 (de) |
DK (1) | DK171251B1 (de) |
ES (1) | ES2087056T3 (de) |
FI (1) | FI91150C (de) |
GR (1) | GR3019455T3 (de) |
HU (1) | HU198708B (de) |
IE (1) | IE74202B1 (de) |
NZ (1) | NZ218924A (de) |
PH (1) | PH25056A (de) |
SG (1) | SG47583A1 (de) |
ZA (1) | ZA87219B (de) |
Families Citing this family (78)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4966622A (en) * | 1988-04-12 | 1990-10-30 | Ciba-Geigy Corporation | N-phenyl-N-pyrimidin-2-ylureas |
FR2632521B1 (fr) * | 1988-06-10 | 1990-09-14 | Rhone Poulenc Sante | Nouveaux derives de la phenothiazine, leur preparation et les compositions pharmaceutiques qui les contiennent |
IE62023B1 (en) * | 1989-01-02 | 1994-12-14 | Boots Co Plc | Therapeutic agents |
GB8903592D0 (en) * | 1989-02-16 | 1989-04-05 | Boots Co Plc | Therapeutic agents |
IN172842B (de) * | 1990-05-17 | 1993-12-11 | Boots Pharmaceuticals Limited | |
CN1037346C (zh) * | 1990-06-29 | 1998-02-11 | 布茨公司 | 降血糖的脒类和胍类的制备方法 |
US5270319A (en) * | 1991-09-09 | 1993-12-14 | Warner-Lambert Company | 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents |
US5162328A (en) * | 1991-12-31 | 1992-11-10 | American Cyanamid Company | N-[3-[2-(1H-imidazol-1-yl)ethoxy]phenyl]-4-(2-thienyl)-2-pyrimidinamine and pharmacologically acceptable salts |
US5220025A (en) * | 1992-02-24 | 1993-06-15 | Warner-Lambert Company | 2-substituted amino-4, 6-di-tertiary-butyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents |
US5196431A (en) * | 1992-02-24 | 1993-03-23 | Warner-Lambert Company | 2-substituted amino-4, 6-di-tertiary-buthyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents |
US5521184A (en) * | 1992-04-03 | 1996-05-28 | Ciba-Geigy Corporation | Pyrimidine derivatives and processes for the preparation thereof |
TW225528B (de) * | 1992-04-03 | 1994-06-21 | Ciba Geigy Ag | |
GB9212673D0 (en) * | 1992-06-15 | 1992-07-29 | Celltech Ltd | Chemical compounds |
US5516775A (en) * | 1992-08-31 | 1996-05-14 | Ciba-Geigy Corporation | Further use of pyrimidine derivatives |
GB9222253D0 (en) * | 1992-10-23 | 1992-12-09 | Celltech Ltd | Chemical compounds |
GB9304919D0 (en) * | 1993-03-10 | 1993-04-28 | Celltech Ltd | Chemical compounds |
GB9304920D0 (en) * | 1993-03-10 | 1993-04-28 | Celltech Ltd | Chemical compounds |
US5612340A (en) * | 1993-10-01 | 1997-03-18 | Ciba-Geigy Corporation | Pyrimidineamine derivatives and processes for the preparation thereof |
ES2262137T3 (es) * | 1993-10-01 | 2006-11-16 | Novartis Ag | Derivados de pirimidinamina farmacologicamente activos y procedimientos para su preparacion. |
ATE208772T1 (de) * | 1993-10-01 | 2001-11-15 | Novartis Erfind Verwalt Gmbh | Pharmacologisch wirksame pyridinderivate und verfahren zu deren herstellung |
US5543520A (en) * | 1993-10-01 | 1996-08-06 | Ciba-Geigy Corporation | Pyrimidine derivatives |
GB9326600D0 (en) * | 1993-12-22 | 1994-03-02 | Celltech Ltd | Chemical compounds |
ATE260911T1 (de) * | 1993-12-22 | 2004-03-15 | Celltech R&D Ltd | Trisubstituierte phenyl-derivate, verfahren zu deren herstellung und deren verwendung als phosphodiesterase (typ iv) hemmstoffe |
US6245774B1 (en) | 1994-06-21 | 2001-06-12 | Celltech Therapeutics Limited | Tri-substituted phenyl or pyridine derivatives |
US5786354A (en) * | 1994-06-21 | 1998-07-28 | Celltech Therapeutics, Limited | Tri-substituted phenyl derivatives and processes for their preparation |
GB9412573D0 (en) * | 1994-06-22 | 1994-08-10 | Celltech Ltd | Chemical compounds |
GB9412571D0 (en) | 1994-06-22 | 1994-08-10 | Celltech Ltd | Chemical compounds |
GB9412672D0 (en) * | 1994-06-23 | 1994-08-10 | Celltech Ltd | Chemical compounds |
GB9523675D0 (en) | 1995-11-20 | 1996-01-24 | Celltech Therapeutics Ltd | Chemical compounds |
GB9526243D0 (en) * | 1995-12-21 | 1996-02-21 | Celltech Therapeutics Ltd | Chemical compounds |
GB9526246D0 (en) * | 1995-12-21 | 1996-02-21 | Celltech Therapeutics Ltd | Chemical compounds |
GB9526245D0 (en) * | 1995-12-21 | 1996-02-21 | Celltech Therapeutics Ltd | Chemical compounds |
ZA9610687B (en) | 1995-12-22 | 1997-09-29 | Smithkline Beecham Corp | Novel synthesis. |
WO1997033883A1 (en) | 1996-03-13 | 1997-09-18 | Smithkline Beecham Corporation | Novel pyrimidine compounds useful in treating cytokine mediated diseases |
GB9608435D0 (en) * | 1996-04-24 | 1996-06-26 | Celltech Therapeutics Ltd | Chemical compounds |
GB9619284D0 (en) * | 1996-09-16 | 1996-10-30 | Celltech Therapeutics Ltd | Chemical compounds |
GB9622363D0 (en) | 1996-10-28 | 1997-01-08 | Celltech Therapeutics Ltd | Chemical compounds |
GB9625184D0 (en) * | 1996-12-04 | 1997-01-22 | Celltech Therapeutics Ltd | Chemical compounds |
JP2001507349A (ja) | 1996-12-23 | 2001-06-05 | セルテック セラピューティックス リミテッド | 縮合多環式2−アミノピリミジン誘導体、それらの製造およびたんぱく質チロシンキナーゼ抑制因子としてのそれらの使用 |
GB9705361D0 (en) * | 1997-03-14 | 1997-04-30 | Celltech Therapeutics Ltd | Chemical compounds |
GB9713087D0 (en) * | 1997-06-20 | 1997-08-27 | Celltech Therapeutics Ltd | Chemical compounds |
JP2002528499A (ja) * | 1998-10-29 | 2002-09-03 | ブリストル−マイヤーズ スクイブ カンパニー | Impdh酵素のインヒビターであるアミノ核誘導化合物 |
US6239279B1 (en) | 1998-12-16 | 2001-05-29 | Smithkline Beecham Corporation | Synthesis for 4-aryl-5-pyrimidine imidazole substituted derivatives |
GB9914258D0 (en) | 1999-06-18 | 1999-08-18 | Celltech Therapeutics Ltd | Chemical compounds |
CA2383546A1 (en) | 1999-06-30 | 2001-01-04 | William H. Parsons | Src kinase inhibitor compounds |
US6329380B1 (en) | 1999-06-30 | 2001-12-11 | Merck & Co., Inc. | SRC kinase inhibitor compounds |
JP2003503354A (ja) | 1999-06-30 | 2003-01-28 | メルク エンド カムパニー インコーポレーテッド | Srcキナーゼ阻害剤化合物 |
GB9924862D0 (en) | 1999-10-20 | 1999-12-22 | Celltech Therapeutics Ltd | Chemical compounds |
WO2001060816A1 (en) * | 2000-02-17 | 2001-08-23 | Amgen Inc. | Kinase inhibitors |
CA2401748A1 (en) * | 2000-03-29 | 2001-10-04 | Cyclacel Limited | 2-substituted 4-heteroaryl-pyrimidines and their use in the treatment of proliferative disorders |
US7429599B2 (en) * | 2000-12-06 | 2008-09-30 | Signal Pharmaceuticals, Llc | Methods for treating or preventing an inflammatory or metabolic condition or inhibiting JNK |
US7122544B2 (en) * | 2000-12-06 | 2006-10-17 | Signal Pharmaceuticals, Llc | Anilinopyrimidine derivatives as IKK inhibitors and compositions and methods related thereto |
US7078410B2 (en) | 2001-02-20 | 2006-07-18 | Astrazeneca Ab | 2-arylamino-pyrimidines for the treatment of GSK3-related disorders |
GB0107901D0 (en) | 2001-03-29 | 2001-05-23 | Cyclacel Ltd | Anti-cancer compounds |
MXPA04002914A (es) | 2001-09-28 | 2005-06-20 | Cyclacel Ltd | N- (4- (4-metiltiazol-5-il)pirimidin-2-il) -n-fenilaminas como compuestos antiproliferativos. |
KR20040062557A (ko) * | 2001-11-01 | 2004-07-07 | 얀센 파마슈티카 엔.브이. | 글리코겐 신타제 키나제 3β 억제제로서의아미노벤즈아미드 유도체 |
EP1448556A1 (de) | 2001-11-01 | 2004-08-25 | Janssen Pharmaceutica N.V. | Heteroarylamine als inhibitoren der glycogensynthasekinase-3-beta (gsk3-inhibitoren) |
AR038368A1 (es) | 2002-02-01 | 2005-01-12 | Novartis Ag | Compuestos n-pirimidin-2-il-aminas sustituidas como inhibidores de ige, una composicion farmaceutica y el uso de dichos compuestos para la preparacion de un medicamento |
GB0222514D0 (en) | 2002-09-27 | 2002-11-06 | Novartis Ag | Organic compounds |
GB0229581D0 (en) * | 2002-12-19 | 2003-01-22 | Cyclacel Ltd | Use |
WO2006021803A2 (en) | 2004-08-27 | 2006-03-02 | Cyclacel Limited | Purine and pyrimidine cdk inhibitors and their use for the treatment of autoimmune diseases |
ES2397362T3 (es) | 2004-12-17 | 2013-03-06 | Amgen Inc. | Compuestos de aminopirimidina como inhibidores de PLK |
GB0500492D0 (en) * | 2005-01-11 | 2005-02-16 | Cyclacel Ltd | Compound |
GB0520958D0 (en) | 2005-10-14 | 2005-11-23 | Cyclacel Ltd | Compound |
JP2009519218A (ja) | 2005-11-03 | 2009-05-14 | エスジーエックス ファーマシューティカルズ、インコーポレイテッド | ピリミジニル−チオフェンキナーゼモジュレータ |
US20100048597A1 (en) * | 2006-12-22 | 2010-02-25 | Novartis Ag | Organic Compounds and Their Uses |
PT2200436E (pt) | 2007-09-04 | 2015-04-29 | Scripps Research Inst | Pirimidinilaminas substituídas como inibidoras da proteína quinase |
BRPI0906799A2 (pt) | 2008-01-11 | 2015-07-14 | Hoffmann La Roche | Moduladores para amiloide beta |
CA2713716A1 (en) * | 2008-02-22 | 2009-08-27 | F. Hoffmann-La Roche Ag | Modulators for amyloid beta |
WO2010040661A1 (en) | 2008-10-09 | 2010-04-15 | F. Hoffmann-La Roche Ag | Modulators for amyloid beta |
EP2355817A1 (de) | 2008-11-10 | 2011-08-17 | F. Hoffmann-La Roche AG | Heterozyklische gamma-secretase-modulatoren |
US8513242B2 (en) | 2008-12-12 | 2013-08-20 | Cystic Fibrosis Foundation Therapeutics, Inc. | Pyrimidine compounds and methods of making and using same |
US8486967B2 (en) | 2010-02-17 | 2013-07-16 | Hoffmann-La Roche Inc. | Heteroaryl substituted piperidines |
US8334292B1 (en) | 2010-06-14 | 2012-12-18 | Cystic Fibrosis Foundation Therapeutics, Inc. | Pyrimidine compounds and methods of making and using same |
WO2013035102A1 (en) | 2011-09-05 | 2013-03-14 | Natco Pharma Limited | Processes for the preparation of imatinib base and intermediates thereof |
RU2486180C1 (ru) * | 2011-11-02 | 2013-06-27 | Общество с ограниченной ответственностью "ТехноХим" (ООО "ТехноХим") | Способ получения 2-ариламино-4-гетарилпиримидинов |
WO2014055972A2 (en) * | 2012-10-05 | 2014-04-10 | The Regents Of The University Of California | A new chemical entity useful for treating various diseases |
CN114181199B (zh) * | 2020-09-15 | 2023-09-26 | 成都赜灵生物医药科技有限公司 | 2,4-二取代嘧啶衍生物及其制备方法和用途 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB735702A (en) * | 1952-03-18 | 1955-08-24 | Wellcome Found | Improvements in and relating to 2,4-diaminopyrimidines and methods of making the same |
US4512993A (en) * | 1983-07-25 | 1985-04-23 | Sterling Drug Inc. | 4(Or 5)-(pyridinyl)-2-pyrimidinamines and cardiotonic use thereof |
US4504482A (en) * | 1983-07-28 | 1985-03-12 | Sterling Drug Inc. | [5(or 4)-(Pyridinyl)-2-pyrimidinyl]ureas and cardiotonic use thereof |
GB8412184D0 (en) * | 1984-05-12 | 1984-06-20 | Fisons Plc | Biologically active nitrogen heterocycles |
EP0164204A1 (de) † | 1984-05-12 | 1985-12-11 | FISONS plc | Pharmazeutisch nützliche Pyrimidine |
US4725600A (en) † | 1984-07-13 | 1988-02-16 | Fujisawa Pharmaceutical Co., Ltd. | Pyrimidine compounds having activity as a cardiotonic anti-hypertensive cerebrovascular vasodilator and anti-platelet aggregation agent |
JPS62501632A (ja) * | 1985-02-05 | 1987-07-02 | ジ・アップジョン・カンパニ− | 4−置換−6−アリ−ルピリミジン化合物 |
US4711888A (en) * | 1985-07-24 | 1987-12-08 | Pfizer Inc. | Hydroxy and alkoxy pyrimidines |
-
1987
- 1987-01-12 ES ES87100277T patent/ES2087056T3/es not_active Expired - Lifetime
- 1987-01-12 SG SG1996002948A patent/SG47583A1/en unknown
- 1987-01-12 AT AT87100277T patent/ATE135699T1/de not_active IP Right Cessation
- 1987-01-12 EP EP87100277A patent/EP0233461B2/de not_active Expired - Lifetime
- 1987-01-12 DE DE3751742T patent/DE3751742T3/de not_active Expired - Fee Related
- 1987-01-13 FI FI870113A patent/FI91150C/fi not_active IP Right Cessation
- 1987-01-13 ZA ZA87219A patent/ZA87219B/xx unknown
- 1987-01-13 JP JP62005867A patent/JPH0780857B2/ja not_active Expired - Lifetime
- 1987-01-13 IE IE7487A patent/IE74202B1/en not_active IP Right Cessation
- 1987-01-13 DK DK015187A patent/DK171251B1/da not_active IP Right Cessation
- 1987-01-13 NZ NZ218924A patent/NZ218924A/en unknown
- 1987-01-13 AU AU67518/87A patent/AU591223B2/en not_active Ceased
- 1987-01-13 HU HU87100A patent/HU198708B/hu not_active IP Right Cessation
- 1987-01-13 CA CA000527173A patent/CA1320201C/en not_active Expired - Fee Related
- 1987-01-13 PH PH34715A patent/PH25056A/en unknown
- 1987-01-15 KR KR1019870000280A patent/KR900004693B1/ko not_active IP Right Cessation
-
1990
- 1990-02-28 AU AU50578/90A patent/AU621461B2/en not_active Ceased
-
1996
- 1996-03-29 GR GR950402384T patent/GR3019455T3/el unknown
-
1997
- 1997-05-14 BR BR1100989-6A patent/BR1100989A/pt active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
FI91150B (fi) | 1994-02-15 |
IE870074L (en) | 1987-07-13 |
DK15187A (da) | 1987-07-14 |
GR3019455T3 (en) | 1996-06-30 |
AU6751887A (en) | 1987-07-16 |
ZA87219B (en) | 1987-08-26 |
JPH0780857B2 (ja) | 1995-08-30 |
KR900004693B1 (ko) | 1990-07-02 |
AU5057890A (en) | 1990-07-26 |
IE74202B1 (en) | 1997-07-16 |
FI870113A (fi) | 1987-07-14 |
DE3751742T3 (de) | 2002-11-21 |
CA1320201C (en) | 1993-07-13 |
EP0233461B2 (de) | 2002-05-29 |
DE3751742T2 (de) | 1996-11-21 |
EP0233461B1 (de) | 1996-03-20 |
ATE135699T1 (de) | 1996-04-15 |
JPS62223177A (ja) | 1987-10-01 |
FI91150C (fi) | 1994-05-25 |
DK15187D0 (da) | 1987-01-13 |
DK171251B1 (da) | 1996-08-12 |
AU621461B2 (en) | 1992-03-12 |
ES2087056T3 (es) | 1996-07-16 |
NZ218924A (en) | 1990-04-26 |
FI870113A0 (fi) | 1987-01-13 |
EP0233461A3 (en) | 1988-05-25 |
EP0233461A2 (de) | 1987-08-26 |
HU198708B (en) | 1989-11-28 |
AU591223B2 (en) | 1989-11-30 |
KR870007154A (ko) | 1987-08-17 |
BR1100989A (pt) | 1999-11-09 |
SG47583A1 (en) | 1998-04-17 |
HUT43582A (en) | 1987-11-30 |
DE3751742D1 (de) | 1996-04-25 |
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