PE20120585A1 - Forma cristalina del fosfato de dihidrogeno r)-3-(4-(2-(2-metiltetrazol-5-il) piridin-5-il)-3-fluorofensil)-5-hidroximetil oxazolidin-2-ona - Google Patents

Forma cristalina del fosfato de dihidrogeno r)-3-(4-(2-(2-metiltetrazol-5-il) piridin-5-il)-3-fluorofensil)-5-hidroximetil oxazolidin-2-ona

Info

Publication number
PE20120585A1
PE20120585A1 PE2011001433A PE2011001433A PE20120585A1 PE 20120585 A1 PE20120585 A1 PE 20120585A1 PE 2011001433 A PE2011001433 A PE 2011001433A PE 2011001433 A PE2011001433 A PE 2011001433A PE 20120585 A1 PE20120585 A1 PE 20120585A1
Authority
PE
Peru
Prior art keywords
hydroximethyl
methyltetrazole
oxazolidin
ona
pyridin
Prior art date
Application number
PE2011001433A
Other languages
English (en)
Inventor
Katharina Reichenbacher
Robert J Duguid
Jacqueline A Simson
Douglas Phillipson
Original Assignee
Trius Therapeutics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42289775&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20120585(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Trius Therapeutics filed Critical Trius Therapeutics
Publication of PE20120585A1 publication Critical patent/PE20120585A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids

Abstract

REFERIDA A UN COMPUESTO FOSFATO DE DI-HIDROGENO CRISTALINO, PURIFICADO (R)-3-(4-(2-(2-METILTETRAZOL-5-IL)PIRIDIN-5-IL)-3-FLUOROFENIL)-5-HIDROXIMETIL OXAZOLIDIN-2-ONA, CARACTERIZADO POR UNA PUREZA DE AL MENOS 96-97% EN PESO Y MUESTRA UN PATRON DSC CON PICOS ENDOTERMICOS DE APROXIMADAMENTE 255-258C. REFERIDA TAMBIEN A UNA COMPOSICION FARMACEUTICA. DICHO CRISTAL ES UTIL EN EL TRATAMIENTO DE INFECCIONES BACTERIALES
PE2011001433A 2009-02-03 2010-02-03 Forma cristalina del fosfato de dihidrogeno r)-3-(4-(2-(2-metiltetrazol-5-il) piridin-5-il)-3-fluorofensil)-5-hidroximetil oxazolidin-2-ona PE20120585A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14940209P 2009-02-03 2009-02-03

Publications (1)

Publication Number Publication Date
PE20120585A1 true PE20120585A1 (es) 2012-06-13

Family

ID=42289775

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2011001433A PE20120585A1 (es) 2009-02-03 2010-02-03 Forma cristalina del fosfato de dihidrogeno r)-3-(4-(2-(2-metiltetrazol-5-il) piridin-5-il)-3-fluorofensil)-5-hidroximetil oxazolidin-2-ona

Country Status (29)

Country Link
US (6) US8426389B2 (es)
EP (1) EP2393808B1 (es)
JP (1) JP5584705B2 (es)
KR (3) KR101739923B1 (es)
CN (2) CN107082790A (es)
AP (1) AP2987A (es)
AU (1) AU2010210627B2 (es)
BR (1) BRPI1008829A2 (es)
CA (1) CA2751392C (es)
CL (1) CL2011001855A1 (es)
CO (1) CO6620071A2 (es)
CR (1) CR20110464A (es)
CU (1) CU24089B1 (es)
DO (1) DOP2011000251A (es)
EC (1) ECSP11011285A (es)
ES (1) ES2734724T3 (es)
IL (1) IL214401B (es)
MA (1) MA33092B1 (es)
MX (2) MX2011008093A (es)
MY (1) MY156354A (es)
NZ (3) NZ594408A (es)
PE (1) PE20120585A1 (es)
PH (1) PH12014500092A1 (es)
RU (2) RU2011136537A (es)
SG (2) SG173497A1 (es)
TN (1) TN2011000381A1 (es)
UA (1) UA114068C2 (es)
WO (1) WO2010091131A1 (es)
ZA (2) ZA201106412B (es)

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CN105837634B (zh) * 2015-01-30 2020-09-04 上海创诺制药有限公司 一种泰地唑胺磷酸酯结晶体及其制备方法
CN104592218B (zh) * 2015-02-13 2015-11-04 江苏欧信医药化工有限公司 一种泰地唑胺的合成方法
CN106146485B (zh) * 2015-04-01 2021-04-30 上海迪赛诺化学制药有限公司 一种制备泰地唑胺的方法及其得到的泰地唑胺结晶体
CN106146558A (zh) * 2015-04-10 2016-11-23 博瑞生物医药（苏州）股份有限公司 新的噁唑烷酮类化合物及其制备方法
CN106317114B (zh) * 2015-07-02 2018-11-20 南京优科制药有限公司 一种磷酸特地唑胺的制备方法
CN105085570B (zh) * 2015-09-12 2017-11-28 山东罗欣药业集团股份有限公司 一种磷酸特地唑胺化合物及其制备方法
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CN107121503B (zh) * 2017-03-14 2020-04-28 南京优科制药有限公司 一种磷酸特地唑胺及其有关物质的分析方法
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KR20110120311A (ko) 2011-11-03
PH12014500092B1 (en) 2014-12-01
ES2734724T3 (es) 2019-12-11
US8426389B2 (en) 2013-04-23
NZ712289A (en) 2017-03-31
MA33092B1 (fr) 2012-03-01
AU2010210627B2 (en) 2016-03-03
US9988406B2 (en) 2018-06-05
CA2751392A1 (en) 2010-08-12
NZ594408A (en) 2014-03-28
CU24089B1 (es) 2015-04-29
RU2655928C1 (ru) 2018-05-30
US20180244704A1 (en) 2018-08-30
ECSP11011285A (es) 2011-10-31
SG173497A1 (en) 2011-09-29
ZA201306536B (en) 2014-05-28
US20130310343A1 (en) 2013-11-21
CU20110155A7 (es) 2012-02-15
US20170275315A1 (en) 2017-09-28
AP2011005835A0 (en) 2011-08-31
US10065947B1 (en) 2018-09-04
EP2393808A1 (en) 2011-12-14
UA114068C2 (xx) 2017-04-25
BRPI1008829A2 (pt) 2016-03-15
US20160176905A1 (en) 2016-06-23
KR101918678B1 (ko) 2018-11-14
ZA201106412B (en) 2013-11-27
CA2751392C (en) 2017-03-28
US10442829B2 (en) 2019-10-15
KR101739923B1 (ko) 2017-05-25
US20180251482A1 (en) 2018-09-06
DOP2011000251A (es) 2011-11-15
MX2011008093A (es) 2011-11-29
SG10201500207QA (en) 2015-03-30
JP2012516894A (ja) 2012-07-26
CN107082790A (zh) 2017-08-22
TN2011000381A1 (en) 2013-03-27
MY156354A (en) 2016-02-15
KR20170135984A (ko) 2017-12-08
CR20110464A (es) 2016-07-20
AU2010210627A1 (en) 2011-08-25
IL214401A0 (en) 2011-09-27
PH12014500092A1 (en) 2014-12-01
US20100227839A1 (en) 2010-09-09
AP2987A (en) 2014-09-30
MX2020011773A (es) 2020-11-24
US9624250B2 (en) 2017-04-18
NZ620458A (en) 2015-10-30
JP5584705B2 (ja) 2014-09-03
WO2010091131A1 (en) 2010-08-12
IL214401B (en) 2021-03-25
CL2011001855A1 (es) 2011-11-11
CO6620071A2 (es) 2013-02-15
KR20170040371A (ko) 2017-04-12
RU2011136537A (ru) 2013-03-10
EP2393808B1 (en) 2019-05-08
CN102439006A (zh) 2012-05-02

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