NO930738L - Nye cyklosporinger, fremgangsmaate for deres fremstilling og farmasoeytiske preparater derav - Google Patents

Nye cyklosporinger, fremgangsmaate for deres fremstilling og farmasoeytiske preparater derav

Info

Publication number
NO930738L
NO930738L NO93930738A NO930738A NO930738L NO 930738 L NO930738 L NO 930738L NO 93930738 A NO93930738 A NO 93930738A NO 930738 A NO930738 A NO 930738A NO 930738 L NO930738 L NO 930738L
Authority
NO
Norway
Prior art keywords
procedures
preparation
pharmaceutical preparations
new cycle
cycle tracks
Prior art date
Application number
NO93930738A
Other languages
English (en)
Other versions
NO930738D0 (no
NO310685B1 (no
Inventor
Johann J Boelsterli
Marcel K Eberle
Reto Naef
Trevor G Payne
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NO930738D0 publication Critical patent/NO930738D0/no
Publication of NO930738L publication Critical patent/NO930738L/no
Publication of NO310685B1 publication Critical patent/NO310685B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • C07K7/645Cyclosporins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Gasification And Melting Of Waste (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO19930738A 1992-03-02 1993-03-01 Nye cyklosporiner, fremgangsmåte for deres fremstilling, anvendelsen herav for fremstilling av medikamenter samtfarmasöytiske preparater inneholdende disse NO310685B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929204466A GB9204466D0 (en) 1992-03-02 1992-03-02 Improvements in or relating to organic compounds

Publications (3)

Publication Number Publication Date
NO930738D0 NO930738D0 (no) 1993-03-01
NO930738L true NO930738L (no) 1993-09-03
NO310685B1 NO310685B1 (no) 2001-08-13

Family

ID=10711333

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19930738A NO310685B1 (no) 1992-03-02 1993-03-01 Nye cyklosporiner, fremgangsmåte for deres fremstilling, anvendelsen herav for fremstilling av medikamenter samtfarmasöytiske preparater inneholdende disse

Country Status (26)

Country Link
US (1) US5643870A (no)
EP (1) EP0577544B1 (no)
JP (1) JP3382656B2 (no)
KR (1) KR100256988B1 (no)
CN (1) CN1037104C (no)
AT (1) ATE146484T1 (no)
AU (1) AU667072B2 (no)
CA (1) CA2090634C (no)
CZ (1) CZ285421B6 (no)
DE (1) DE69306670T2 (no)
DK (1) DK0577544T3 (no)
ES (1) ES2096262T3 (no)
FI (1) FI111729B (no)
GB (1) GB9204466D0 (no)
GR (1) GR3022539T3 (no)
HU (1) HU214028B (no)
IL (1) IL104891A (no)
MX (1) MX9301129A (no)
MY (1) MY106921A (no)
NO (1) NO310685B1 (no)
NZ (1) NZ247031A (no)
PL (1) PL174816B1 (no)
RU (1) RU2131883C1 (no)
SK (1) SK279529B6 (no)
TW (1) TW264472B (no)
ZA (1) ZA931491B (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639852A (en) * 1994-09-01 1997-06-17 Wisconsin Alumni Research Foundation Immunostimulatory agents
CN1130373C (zh) * 1996-09-13 2003-12-10 诺瓦蒂斯有限公司 [3'-脱氧-3'-氧代-MeBmt]'环孢菌素制备方法
US6517860B1 (en) 1996-12-31 2003-02-11 Quadrant Holdings Cambridge, Ltd. Methods and compositions for improved bioavailability of bioactive agents for mucosal delivery
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
ATE423130T1 (de) * 1997-10-08 2009-03-15 Isotechnika Inc Deuterierte cyclosporin-analoga und ihre verwendung als immunmodulierende agenzien
US6784156B2 (en) * 2001-03-05 2004-08-31 Enanta Pharmaceuticals, Inc. Cyclosporins for the treatment of respiratory diseases
US20030087813A1 (en) * 2001-10-12 2003-05-08 Or Yat Sun Cyclosporin analogs for the treatment of lung diseases
US6809077B2 (en) * 2001-10-12 2004-10-26 Enanta Pharmaceuticals, Inc. Cyclosporin analogs for the treatment of autoimmune diseases
ATE425178T1 (de) * 2001-10-19 2009-03-15 Isotechnika Inc Synthese von cyclosporinanalogen
US7012065B2 (en) * 2003-02-07 2006-03-14 Enanta Pharmaceuticals, Inc. Cyclosporins for the treatment of immune disorders
EP1603512A2 (en) * 2003-03-17 2005-12-14 Albany Molecular Research, Inc. Novel cyclosporins
US20040266669A1 (en) * 2003-06-20 2004-12-30 Wu Frank X. H. Cyclosporin derivatives for the treatment of immune disorders
JP2006014722A (ja) 2004-06-02 2006-01-19 Keio Gijuku 遺伝子マーカー及びその利用
JP2008514701A (ja) * 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド シクロスポリンアルキン類似体およびそれらの薬学的使用
JP2008514702A (ja) * 2004-09-29 2008-05-08 エーエムアール テクノロジー インコーポレイテッド 新規シクロスポリン類似体およびそれらの薬学的使用
US7361636B2 (en) * 2004-10-06 2008-04-22 Amr Technology, Inc. Cyclosporin alkynes and their utility as pharmaceutical agents
US7696167B2 (en) * 2004-11-22 2010-04-13 Astellas Pharma Inc. Cyclic peptide compound
US7696166B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US7696165B2 (en) * 2006-03-28 2010-04-13 Albany Molecular Research, Inc. Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
CA3014633C (en) 2007-10-08 2022-05-17 Aurinia Pharmaceuticals Inc. Ophthalmic compositions comprising calcineurin inhibitors or mtor inhibitors
AU2009276241A1 (en) * 2008-07-30 2010-02-04 Ciclofilin Pharmaceuticals Corp. Nonimmunosuppressive cyclosporine analogue molecules
ES2537385T3 (es) 2009-06-09 2015-06-08 Aurinia Pharmaceuticals Inc. Sistemas de suministro tópico para uso oftálmico
US20130267460A1 (en) * 2010-09-16 2013-10-10 The Johns Hopkins University Methods of Inhibiting Alphavirus Replication and Treating Alphavirus Infection
KR102305423B1 (ko) 2010-12-15 2021-09-27 콘트라빌 파마슈티컬스, 인코퍼레이티드 아미노산 1 및 3에서 변형된 사이클로스포린 유사체 분자
CN105076117B (zh) * 2014-10-31 2017-08-25 北京林业大学 一种种子抗老化剂及其制备方法
KR20170000243U (ko) 2015-07-09 2017-01-18 (주)하나피앤씨 배관연결용 플랜지 기구
US9981041B2 (en) * 2016-08-23 2018-05-29 Ira Jason Salzman Ophthalmic lubricating spray
US20190224275A1 (en) 2017-05-12 2019-07-25 Aurinia Pharmaceuticals Inc. Protocol for treatment of lupus nephritis

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2819094A1 (de) * 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
EP0194972B1 (en) * 1985-03-11 1992-07-29 Sandoz Ag Novel cyclosporins
US4649047A (en) * 1985-03-19 1987-03-10 University Of Georgia Research Foundation, Inc. Ophthalmic treatment by topical administration of cyclosporin
US4764503A (en) * 1986-11-19 1988-08-16 Sandoz Ltd. Novel cyclosporins
EP0283801A3 (en) * 1987-03-27 1990-05-30 Abbott Laboratories Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
US4798823A (en) * 1987-06-03 1989-01-17 Merck & Co., Inc. New cyclosporin analogs with modified "C-9 amino acids"
ES2059558T3 (es) * 1987-06-17 1994-11-16 Sandoz Ag Ciclosporins y su uso como productos farmaceuticos.
US4839342A (en) * 1987-09-03 1989-06-13 University Of Georgia Research Foundation, Inc. Method of increasing tear production by topical administration of cyclosporin
AU4958590A (en) * 1988-12-05 1990-07-10 Trustees Of Columbia University In The City Of New York, The Novel derivatives of cyclosporine a, antibodies directed thereto and uses thereof
US4996193A (en) * 1989-03-03 1991-02-26 The Regents Of The University Of California Combined topical and systemic method of administration of cyclosporine
GB8916901D0 (en) * 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
US5202310A (en) * 1990-06-06 1993-04-13 Levy Gary A Cyclosporine metabolites
ES2095926T5 (es) * 1990-11-02 2001-02-16 Novartis Ag Cyclosporins.

Also Published As

Publication number Publication date
RU2131883C1 (ru) 1999-06-20
JP3382656B2 (ja) 2003-03-04
ATE146484T1 (de) 1997-01-15
GB9204466D0 (en) 1992-04-15
CZ285421B6 (cs) 1999-08-11
CN1037104C (zh) 1998-01-21
DE69306670T2 (de) 1997-07-03
IL104891A0 (en) 1993-07-08
CA2090634A1 (en) 1993-09-03
US5643870A (en) 1997-07-01
KR100256988B1 (ko) 2000-05-15
NO930738D0 (no) 1993-03-01
SK14093A3 (en) 1993-10-06
NO310685B1 (no) 2001-08-13
TW264472B (no) 1995-12-01
AU667072B2 (en) 1996-03-07
HU214028B (en) 1997-12-29
CN1076453A (zh) 1993-09-22
NZ247031A (en) 1995-05-26
JPH07252296A (ja) 1995-10-03
MY106921A (en) 1995-08-30
EP0577544B1 (en) 1996-12-18
CZ30393A3 (en) 1994-02-16
EP0577544A1 (en) 1994-01-05
IL104891A (en) 1997-04-15
PL174816B1 (pl) 1998-09-30
ZA931491B (en) 1994-09-02
FI111729B (fi) 2003-09-15
SK279529B6 (sk) 1998-12-02
PL297902A1 (en) 1993-09-06
AU3387293A (en) 1993-09-09
HU9300418D0 (en) 1993-05-28
ES2096262T3 (es) 1997-03-01
KR930019692A (ko) 1993-10-18
FI930912A0 (fi) 1993-03-01
CA2090634C (en) 2005-12-13
DE69306670D1 (de) 1997-01-30
DK0577544T3 (da) 1997-04-01
FI930912A (fi) 1993-09-03
GR3022539T3 (en) 1997-05-31
HUT64567A (en) 1994-01-28
MX9301129A (es) 1994-07-29

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