NO752731L - - Google Patents

Info

Publication number
NO752731L
NO752731L NO752731A NO752731A NO752731L NO 752731 L NO752731 L NO 752731L NO 752731 A NO752731 A NO 752731A NO 752731 A NO752731 A NO 752731A NO 752731 L NO752731 L NO 752731L
Authority
NO
Norway
Application number
NO752731A
Other languages
Norwegian (no)
Other versions
NO143460C (no
NO143460B (no
Inventor
H Merz
A Langbein
G Walther
K Stockhaus
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of NO752731L publication Critical patent/NO752731L/no
Publication of NO143460B publication Critical patent/NO143460B/no
Publication of NO143460C publication Critical patent/NO143460C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO752731A 1974-08-05 1975-08-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzomorfaner. NO143460C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2437610A DE2437610A1 (de) 1974-08-05 1974-08-05 Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung

Publications (3)

Publication Number Publication Date
NO752731L true NO752731L (fi) 1976-02-06
NO143460B NO143460B (no) 1980-11-10
NO143460C NO143460C (no) 1981-02-18

Family

ID=5922448

Family Applications (1)

Application Number Title Priority Date Filing Date
NO752731A NO143460C (no) 1974-08-05 1975-08-04 Analogifremgangsmaate for fremstilling av terapeutisk aktive benzomorfaner.

Country Status (27)

Country Link
US (1) US3982005A (fi)
JP (1) JPS60358B2 (fi)
AT (1) AT348140B (fi)
BE (1) BE832099R (fi)
BG (3) BG25090A3 (fi)
CA (1) CA1049008A (fi)
CH (7) CH613963A5 (fi)
CS (1) CS189717B2 (fi)
DD (1) DD122685A5 (fi)
DE (1) DE2437610A1 (fi)
DK (1) DK138992C (fi)
ES (6) ES452765A1 (fi)
FI (1) FI63229C (fi)
FR (1) FR2320096A2 (fi)
GB (1) GB1513950A (fi)
HU (1) HU177952B (fi)
IE (1) IE42216B1 (fi)
IL (1) IL47860A (fi)
LU (1) LU73138A1 (fi)
NL (1) NL7509249A (fi)
NO (1) NO143460C (fi)
PH (1) PH13687A (fi)
PL (3) PL99819B1 (fi)
RO (3) RO67390A (fi)
SE (1) SE425392B (fi)
SU (3) SU591147A3 (fi)
ZA (1) ZA754997B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087532A (en) * 1974-03-09 1978-05-02 Boehringer Ingelheim Gmbh Analgesically useful 2-tetrahydrofurfuryl-5-lower alkyl-2-oxy-6,7-benzomorphans and salts thereof
GB1575009A (en) * 1976-06-21 1980-09-17 Acf Chemiefarma Nv 6,7-benzomorphan derivatives
DE2716687A1 (de) * 1977-04-15 1978-10-19 Boehringer Sohn Ingelheim 2'-hydroxy-2-(5-isoxazolylmethyl)-6,7benzomorphane, deren saeureadditionssalze und diese enthaltende arzneimittel
NL7804509A (nl) * 1978-04-26 1979-10-30 Acf Chemiefarma Nv Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan.
DE2828039A1 (de) * 1978-06-26 1980-01-10 Boehringer Sohn Ingelheim 2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
JPS5636521A (en) * 1979-08-31 1981-04-09 Shin Etsu Chem Co Ltd Production of alkenyloxy group-containing organopolysiloxane
ES2395081T3 (es) 2007-07-26 2013-02-08 Vitae Pharmaceuticals, Inc. Síntesis de inhibidores de la 11beta-hidroxiesteroide deshidrogenasa de tipo 1
EP2220048B1 (en) 2007-11-16 2017-01-25 Boehringer Ingelheim International GmbH Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
JP5490014B2 (ja) 2007-12-11 2014-05-14 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １１β−ヒドロキシステロイドデヒドロゲナーゼ１型の環状尿素阻害剤
TW200934490A (en) 2008-01-07 2009-08-16 Vitae Pharmaceuticals Inc Lactam inhibitors of 11 &abgr;-hydroxysteroid dehydrogenase 1
CA2712500A1 (en) 2008-01-24 2009-07-30 Vitae Pharmaceuticals, Inc. Cyclic carbazate and semicarbazide inhibitors of 11beta-hydroxysteroid dehydrogenase 1
EP2254872A2 (en) 2008-02-15 2010-12-01 Vitae Pharmaceuticals, Inc. Cycloalkyl lactame derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
CA2723034A1 (en) 2008-05-01 2009-11-05 Vitae Pharmaceuticals, Inc. Cyclic inhibitors of 11beta-hydroxysteroid dehydrogenase 1
CL2009001059A1 (es) 2008-05-01 2010-11-12 Boehringer Ingelheim Int Compuestos derivados de 1,3-oxazin-2-ona-3,6 sustituidos, inhibidores de la actividad de la 11-beta-hidroxiesteroide deshidrogenasa i; composicion farmaceutica que los comprende; utiles en el tratamiento de enfermedades tales como diabetes mellitus, entre otras.
AR071236A1 (es) 2008-05-01 2010-06-02 Vitae Pharmaceuticals Inc Inhibidores ciclicos de la 11beta-hidroxiesteroide deshidrogenasa 1
CL2009001151A1 (es) 2008-05-13 2010-08-13 Boehringer Ingelheim Int Compuestos derivados de acidos carbociclicos aliciclicos de benzomorfanos, procedimiento de preparacion, composicion farmaceutica, utiles para tratar enfermedades influenciadas por la inhibicion de la enzima 11beta-hidroxiesteroide deshidrogenasa, como trastornos metabolicos.
WO2010010157A2 (en) 2008-07-25 2010-01-28 Boehringer Ingelheim International Gmbh INHIBITORS OF 11beta-HYDROXYSTEROID DEHYDROGENASE 1
CN102119160B (zh) 2008-07-25 2014-11-05 贝林格尔·英格海姆国际有限公司 11β-羟基类固醇脱氢酶1的环状抑制剂
UA109255C2 (ru) 2009-04-30 2015-08-10 Берінгер Інгельхайм Інтернешнл Гмбх Циклические ингибиторы 11бета-гидроксистероиддегидрогеназы 1
JP5656986B2 (ja) 2009-06-11 2015-01-21 ヴァイティー ファーマシューティカルズ，インコーポレイテッド １，３−オキサジナン−２−オン構造に基づく１１β−ヒドロキシステロイドデヒドロゲナーゼ１の環状阻害剤
TWI531571B (zh) 2009-11-06 2016-05-01 維它藥物公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜芳基羰基衍生物
JP5860042B2 (ja) 2010-06-16 2016-02-16 ヴァイティー ファーマシューティカルズ，インコーポレイテッド 置換５、６及び７員複素環、そのような化合物を含有する医薬及びそれらの使用
TWI537258B (zh) 2010-11-05 2016-06-11 百靈佳殷格翰國際股份有限公司 六氫茚并吡啶及八氫苯并喹啉之芳基－及雜環芳基羰基衍生物
JP2014524438A (ja) 2011-08-17 2014-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング インデノピリジン誘導体
US20240002606A1 (en) 2020-11-26 2024-01-04 Shin-Etsu Chemical Co., Ltd. Room temperature curable organopolysiloxane composition, article, hydrolyzable organosilane compound and method for producing same
JPWO2023032745A1 (fi) 2021-09-03 2023-03-09

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE582575A (fi) * 1958-09-22
US3700734A (en) * 1969-01-23 1972-10-24 Merck & Co Inc 2{40 -hydroxy-2,3,5-trimethyl-6,7-benzomorphan
DE2105743C3 (de) * 1971-02-08 1979-11-29 Boehringer Sohn Ingelheim 2-(Furylmethyl)- a -5,9-dialkyl -6,7benzomorphane, Verfahren zu ihrer Herstellung und deren Verwendung
CS166801B2 (fi) * 1971-02-08 1976-03-29 Boehringer Sohn Ingelheim
DE2200596A1 (de) * 1972-01-07 1973-07-12 Boehringer Sohn Ingelheim N-(furyl-methyl)-2'-hydroxy-5-phenyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung
DE2217420C3 (de) * 1972-04-12 1981-03-12 C.H. Boehringer Sohn, 6507 Ingelheim N-Thienylmethyl-Heterocyclen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zubereitungen
DE2229695A1 (de) * 1972-06-19 1974-01-31 Boehringer Sohn Ingelheim 2-(heteroaryl-methyl)-5,9 beta-dialkyl6,7-benzomorphane, deren saeureadditionssalze sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
US3982005A (en) 1976-09-21
CH616421A5 (fi) 1980-03-31
AT348140B (de) 1979-01-25
IE42216L (en) 1976-02-05
ZA754997B (en) 1977-04-27
LU73138A1 (fi) 1977-04-13
SU587859A3 (ru) 1978-01-05
JPS60358B2 (ja) 1985-01-07
HU177952B (en) 1982-02-28
CS189717B2 (en) 1979-04-30
CA1049008A (en) 1979-02-20
DE2437610A1 (de) 1976-02-26
IE42216B1 (en) 1980-07-02
PH13687A (en) 1980-09-01
RO67390A (ro) 1981-06-30
AU8364675A (en) 1977-02-10
RO72736A (ro) 1982-09-09
SE425392B (sv) 1982-09-27
PL99816B1 (pl) 1978-08-31
NL7509249A (nl) 1976-02-09
IL47860A (en) 1979-01-31
CH615679A5 (fi) 1980-02-15
CH615677A5 (fi) 1980-02-15
ATA523775A (de) 1978-06-15
CH616420A5 (fi) 1980-03-31
NO143460C (no) 1981-02-18
DK352875A (da) 1976-02-06
BE832099R (fr) 1976-02-04
JPS5139673A (en) 1976-04-02
DD122685A5 (fi) 1976-10-20
NO143460B (no) 1980-11-10
DK138992B (da) 1978-11-27
FR2320096B2 (fi) 1978-09-01
ES452764A1 (es) 1977-10-16
SU587858A3 (ru) 1978-01-05
DK138992C (da) 1979-04-30
SE7508789L (sv) 1976-02-10
BG25088A3 (en) 1978-07-12
ES452763A1 (es) 1977-10-01
FI63229C (fi) 1983-05-10
IL47860A0 (en) 1975-11-25
ES452767A1 (es) 1977-10-01
BG25090A3 (en) 1978-07-12
PL99819B1 (pl) 1978-08-31
CH615678A5 (fi) 1980-02-15
FI752211A (fi) 1976-02-06
ES452768A1 (es) 1977-10-01
ES452766A1 (es) 1977-10-01
RO72735A (ro) 1982-09-09
PL99838B1 (pl) 1978-08-31
ES452765A1 (es) 1977-10-16
GB1513950A (en) 1978-06-14
FI63229B (fi) 1983-01-31
CH615680A5 (fi) 1980-02-15
CH613963A5 (fi) 1979-10-31
FR2320096A2 (fr) 1977-03-04
BG25089A3 (en) 1978-07-12
SU591147A3 (ru) 1978-01-30

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