NO322825B1 - Kinazolinoner, syntese av slike, anvendelse av slike for fremstilling av medikamenter for behandling av proliferative sykdommer, farmasoytiske preparater inneholdende slike forbindelser samt anvendelse in vitro for a hemme KSP-kinase. - Google Patents

Kinazolinoner, syntese av slike, anvendelse av slike for fremstilling av medikamenter for behandling av proliferative sykdommer, farmasoytiske preparater inneholdende slike forbindelser samt anvendelse in vitro for a hemme KSP-kinase. Download PDF

Info

Publication number: NO322825B1
Authority: NO; Norway
Prior art keywords: hydrogen; benzyl; ksp; compounds; ethyl
Prior art date: 1999-10-27

Application number

NO20021907A

Other languages

English (en)

Norwegian (no)

Other versions

NO20021907L (no

NO20021907D0 (no

Inventor

Jeffrey T Finer

Gustav Bergnes

Bainian Feng

Whitney W Smith

John C Chabala

Original Assignee

Cytokinetics Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-27

Filing date

2002-04-23

Publication date

2006-12-11

2002-04-23 Application filed by Cytokinetics Inc filed Critical Cytokinetics Inc

2002-04-23 Publication of NO20021907D0 publication Critical patent/NO20021907D0/no

2002-06-07 Publication of NO20021907L publication Critical patent/NO20021907L/no

2006-12-11 Publication of NO322825B1 publication Critical patent/NO322825B1/no

Links

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Classifications

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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Paints Or Removers (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Investigating Or Analysing Biological Materials (AREA)
Medicines Containing Plant Substances (AREA)

NO20021907A 1999-10-27 2002-04-23 Kinazolinoner, syntese av slike, anvendelse av slike for fremstilling av medikamenter for behandling av proliferative sykdommer, farmasoytiske preparater inneholdende slike forbindelser samt anvendelse in vitro for a hemme KSP-kinase. NO322825B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US19825399P	1999-10-27	1999-10-27
US21310400P	2000-06-21	2000-06-21
PCT/US2000/029585 WO2001030768A1 (en)	1999-10-27	2000-10-26	Methods and compositions utilizing quinazolinones

Publications (3)

Publication Number	Publication Date
NO20021907D0 NO20021907D0 (no)	2002-04-23
NO20021907L NO20021907L (no)	2002-06-07
NO322825B1 true NO322825B1 (no)	2006-12-11

Family

ID=26893612

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Application Number	Title	Priority Date	Filing Date
NO20021907A NO322825B1 (no)	1999-10-27	2002-04-23	Kinazolinoner, syntese av slike, anvendelse av slike for fremstilling av medikamenter for behandling av proliferative sykdommer, farmasoytiske preparater inneholdende slike forbindelser samt anvendelse in vitro for a hemme KSP-kinase.

Country Status (19)

Country	Link
EP (2)	EP1226129B1 (ko)
JP (2)	JP2003512461A (ko)
KR (2)	KR20020062930A (ko)
CN (1)	CN100381428C (ko)
AT (1)	ATE327224T1 (ko)
AU (2)	AU774748B2 (ko)
BR (1)	BR0015110A (ko)
CA (1)	CA2388646C (ko)
CZ (1)	CZ20021428A3 (ko)
DE (1)	DE60028227T2 (ko)
ES (1)	ES2263501T3 (ko)
HK (1)	HK1045994A1 (ko)
HU (1)	HUP0203430A3 (ko)
IL (2)	IL149164A0 (ko)
MX (1)	MXPA02004162A (ko)
NO (1)	NO322825B1 (ko)
NZ (2)	NZ518480A (ko)
PL (1)	PL203998B1 (ko)
WO (1)	WO2001030768A1 (ko)

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US7230000B1 (en)	1999-10-27	2007-06-12	Cytokinetics, Incorporated	Methods and compositions utilizing quinazolinones
US6545004B1 (en) *	1999-10-27	2003-04-08	Cytokinetics, Inc.	Methods and compositions utilizing quinazolinones
US7671200B2 (en)	1999-10-27	2010-03-02	Cytokinetics, Inc.	Quinazolinone KSP inhibitors
US8852937B2 (en)	2000-03-30	2014-10-07	Curis, Inc.	Small organic molecule regulators of cell proliferation
US7115653B2 (en)	2000-03-30	2006-10-03	Curis, Inc.	Small organic molecule regulators of cell proliferation
US6667300B2 (en)	2000-04-25	2003-12-23	Icos Corporation	Inhibitors of human phosphatidylinositol 3-kinase delta
JP4259877B2 (ja) *	2000-12-11	2009-04-30	アムジエン・インコーポレーテツド	Ｃｘｃｒ３アンタゴニスト
US6992082B2 (en)	2001-01-19	2006-01-31	Cytokinetics, Inc.	Phenothiazine kinesin inhibitors
US6900214B2 (en)	2001-03-29	2005-05-31	Bristol-Myers Squibb Company	Cyano-substituted dihydropyrimidine compounds and their use to treat diseases
US6809102B2 (en)	2001-03-29	2004-10-26	Bristol-Myers Squibb Company	Cyano-substituted dihydropyrimidine compounds and their use to treat diseases
US6794379B2 (en)	2001-06-06	2004-09-21	Tularik Inc.	CXCR3 antagonists
OA12624A (en)	2001-06-22	2006-06-12	Pfizer Prod Inc	Pharmaceutical compositions comprising low-solubility and/or acid-sensitive drugs and neutralized acidic polymers.
WO2003020279A2 (en) *	2001-09-05	2003-03-13	Minerva Biotechnologies Corporation	Compositions and methods of treatment of cancer
US7060705B2 (en)	2001-11-07	2006-06-13	Merck & Co., Inc.	Mitotic kinesin inhibitors
AU2002366103A1 (en)	2001-11-19	2003-06-10	Iconix Pharmaceuticals, Inc.	Modulators of rho c activity
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DE60028227T2 (de)	2007-03-29
WO2001030768A9 (en)	2002-08-15
PL354891A1 (en)	2004-03-22
CA2388646A1 (en)	2001-05-03
NO20021907L (no)	2002-06-07
AU1439801A (en)	2001-05-08
CZ20021428A3 (cs)	2002-11-13
PL203998B1 (pl)	2009-11-30
NZ530074A (en)	2005-03-24
ES2263501T3 (es)	2006-12-16
CN1413198A (zh)	2003-04-23
AU774748B2 (en)	2004-07-08
MXPA02004162A (es)	2003-08-20
IL149164A (en)	2007-05-15
AU2004218601A1 (en)	2004-10-28
JP2003512461A (ja)	2003-04-02
DE60028227D1 (de)	2006-06-29
CA2388646C (en)	2009-01-27
NO20021907D0 (no)	2002-04-23
HUP0203430A3 (en)	2003-07-28
KR20050049562A (ko)	2005-05-25
HK1045994A1 (en)	2002-12-20
JP2003048881A (ja)	2003-02-21
CN100381428C (zh)	2008-04-16
EP1226129B1 (en)	2006-05-24
EP1686120A3 (en)	2007-05-30
NZ518480A (en)	2004-02-27
ATE327224T1 (de)	2006-06-15
BR0015110A (pt)	2002-07-02
JP4116332B2 (ja)	2008-07-09
WO2001030768A1 (en)	2001-05-03
KR20020062930A (ko)	2002-07-31
IL149164A0 (en)	2002-11-10
HUP0203430A2 (en)	2003-05-28
EP1226129A1 (en)	2002-07-31
EP1686120A2 (en)	2006-08-02

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Publication	Publication Date	Title
NO322825B1 (no)	2006-12-11	Kinazolinoner, syntese av slike, anvendelse av slike for fremstilling av medikamenter for behandling av proliferative sykdommer, farmasoytiske preparater inneholdende slike forbindelser samt anvendelse in vitro for a hemme KSP-kinase.
NO324440B1 (no)	2007-10-15	Kinazolinoner, anvendelse av disse forbindelsene som medikament og i farmasoytiske preparater, anvendelse av disse forbindelsene for fremstilling av medikamenter for behandling av sykdommer og en in vitro metode for a hemme KSP-kinesin basert pa slike forbindelser
US7230000B1 (en)	2007-06-12	Methods and compositions utilizing quinazolinones
US8008311B2 (en)	2011-08-30	Methods and compostions utilizing quinazolinones
AU2001259270A1 (en)	2002-03-21	Methods and compositions utilizing quinazolinones
ZA200210133B (en)	2003-06-17	Methods and compositions utilizing quinazolinones.