NO20091244L - Adenosinderivater som A2A reseptoragonister - Google Patents

Adenosinderivater som A2A reseptoragonister

Info

Publication number
NO20091244L
NO20091244L NO20091244A NO20091244A NO20091244L NO 20091244 L NO20091244 L NO 20091244L NO 20091244 A NO20091244 A NO 20091244A NO 20091244 A NO20091244 A NO 20091244A NO 20091244 L NO20091244 L NO 20091244L
Authority
NO
Norway
Prior art keywords
receptor agonists
adenosine derivatives
stereoisomers
compounds
pharmaceutically acceptable
Prior art date
Application number
NO20091244A
Other languages
English (en)
Inventor
Roger John Taylor
Robin Alec Fairhurst
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of NO20091244L publication Critical patent/NO20091244L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

En forbindelse med formel (I), eller stereoisomerer eller farmasøytisk akseptable salter derav, (I) eller stereoisomerer eller farmasøytisk akseptable salter derav, hvori A, Ui, U2, Rla, Rlb, R2 og R3 har betydningene indikert i beskrivelsen, er anvendelige for behandling av tilstander mediert av aktivering av adenosin A2A reseptoren, særlig inflammatoriske eller obstruktive luftveissykdommer. Farmasøytiske sammensetninger som inneholder forbindelsene og en fremgangsmåte for fremstilling av forbindelser er også beskrevet.
NO20091244A 2006-09-14 2009-03-25 Adenosinderivater som A2A reseptoragonister NO20091244L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06120706A EP1903044A1 (en) 2006-09-14 2006-09-14 Adenosine Derivatives as A2A Receptor Agonists
PCT/EP2007/059666 WO2008031875A1 (en) 2006-09-14 2007-09-13 Adenosine derivatives as a2a receptor agonists

Publications (1)

Publication Number Publication Date
NO20091244L true NO20091244L (no) 2009-04-07

Family

ID=37622170

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20091244A NO20091244L (no) 2006-09-14 2009-03-25 Adenosinderivater som A2A reseptoragonister

Country Status (31)

Country Link
US (1) US8188100B2 (no)
EP (2) EP1903044A1 (no)
JP (1) JP2010503639A (no)
KR (1) KR20090040386A (no)
CN (1) CN101511831B (no)
AR (1) AR062768A1 (no)
AT (1) ATE481404T1 (no)
AU (1) AU2007296227A1 (no)
BR (1) BRPI0716936A2 (no)
CA (1) CA2662104A1 (no)
CL (1) CL2007002658A1 (no)
CR (1) CR10621A (no)
CY (1) CY1110990T1 (no)
DE (1) DE602007009272D1 (no)
DK (1) DK2066669T3 (no)
ES (1) ES2353141T3 (no)
HK (1) HK1131392A1 (no)
HR (1) HRP20100694T1 (no)
IL (1) IL197153A0 (no)
MA (1) MA30722B1 (no)
MX (1) MX2009002811A (no)
NO (1) NO20091244L (no)
PE (1) PE20081151A1 (no)
PL (1) PL2066669T3 (no)
PT (1) PT2066669E (no)
RU (1) RU2009113668A (no)
SI (1) SI2066669T1 (no)
TN (1) TN2009000084A1 (no)
TW (1) TW200821324A (no)
WO (1) WO2008031875A1 (no)
ZA (1) ZA200901036B (no)

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US8188100B2 (en) 2012-05-29
TW200821324A (en) 2008-05-16
CR10621A (es) 2009-03-27
ZA200901036B (en) 2010-01-27
CN101511831B (zh) 2012-04-25
AR062768A1 (es) 2008-12-03
HRP20100694T1 (hr) 2011-01-31
EP2066669A1 (en) 2009-06-10
DK2066669T3 (da) 2011-01-10
WO2008031875A1 (en) 2008-03-20
DE602007009272D1 (de) 2010-10-28
PT2066669E (pt) 2010-12-17
IL197153A0 (en) 2009-11-18
RU2009113668A (ru) 2010-10-20
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JP2010503639A (ja) 2010-02-04
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US20090325967A1 (en) 2009-12-31
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CA2662104A1 (en) 2008-03-20
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KR20090040386A (ko) 2009-04-23
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ATE481404T1 (de) 2010-10-15
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SI2066669T1 (sl) 2011-01-31

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