NO20090224L - Anti-IL-6 monoklonale antistoffer og anvendelser derav - Google Patents

Anti-IL-6 monoklonale antistoffer og anvendelser derav

Info

Publication number
NO20090224L
NO20090224L NO20090224A NO20090224A NO20090224L NO 20090224 L NO20090224 L NO 20090224L NO 20090224 A NO20090224 A NO 20090224A NO 20090224 A NO20090224 A NO 20090224A NO 20090224 L NO20090224 L NO 20090224L
Authority
NO
Norway
Prior art keywords
monoclonal antibodies
amino acid
well
region selected
regions
Prior art date
Application number
NO20090224A
Other languages
English (en)
Norwegian (no)
Inventor
Ernest S Smith
Wei Wang
Original Assignee
Vaccinex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaccinex Inc filed Critical Vaccinex Inc
Publication of NO20090224L publication Critical patent/NO20090224L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
NO20090224A 2006-08-03 2009-01-15 Anti-IL-6 monoklonale antistoffer og anvendelser derav NO20090224L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83510706P 2006-08-03 2006-08-03
PCT/US2007/017337 WO2008019061A2 (fr) 2006-08-03 2007-08-03 Anticorps monoclonaux anti-il-6 et leurs utilisations

Publications (1)

Publication Number Publication Date
NO20090224L true NO20090224L (no) 2009-03-31

Family

ID=39033490

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20090224A NO20090224L (no) 2006-08-03 2009-01-15 Anti-IL-6 monoklonale antistoffer og anvendelser derav

Country Status (17)

Country Link
US (1) US7919095B2 (fr)
EP (1) EP2064241B1 (fr)
JP (1) JP2009545319A (fr)
KR (1) KR101479537B1 (fr)
CN (1) CN101563365B (fr)
AU (1) AU2007282023B2 (fr)
BR (1) BRPI0715115A2 (fr)
CA (1) CA2657763C (fr)
CO (1) CO6150192A2 (fr)
CR (1) CR10563A (fr)
EA (1) EA200900037A1 (fr)
IL (1) IL196550A0 (fr)
MA (1) MA30653B1 (fr)
MX (1) MX2009001110A (fr)
NO (1) NO20090224L (fr)
WO (1) WO2008019061A2 (fr)
ZA (1) ZA200900514B (fr)

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US8404235B2 (en) 2007-05-21 2013-03-26 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
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US7906117B2 (en) 2007-05-21 2011-03-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat cachexia, weakness, fatigue, and/or fever
EP2297202B1 (fr) 2008-05-13 2016-01-13 NovImmune SA Anticorps anti-il-6/il-6r et procédés d'utilisation
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US9212223B2 (en) 2008-11-25 2015-12-15 Alderbio Holdings Llc Antagonists of IL-6 to prevent or treat thrombosis
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US8420089B2 (en) 2008-11-25 2013-04-16 Alderbio Holdings Llc Antagonists of IL-6 to raise albumin and/or lower CRP
US8337847B2 (en) 2008-11-25 2012-12-25 Alderbio Holdings Llc Methods of treating anemia using anti-IL-6 antibodies
JP5913103B2 (ja) 2009-09-14 2016-04-27 ザ リージェンツ オブ ザ ユニバーシティ オブ コロラド，ア ボディー コーポレイトＴＨＥ ＲＥＧＥＮＴＳ ＯＦ ＴＨＥ ＵＮＩＶＥＲＳＩＴＹ ＯＦ ＣＯＬＯＲＡＤＯ，ａ ｂｏｄｙ ｃｏｒｐｏｒａｔｅ 酵母ベースの免疫療法組成物を含む組合せ物及び被験者のスクリーニング方法
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CN114375205A (zh) 2019-06-20 2022-04-19 武田药品工业株式会社 用基于病毒的基因疗法进行治疗的方法
CN112279913B (zh) * 2020-10-30 2022-05-03 上海百英生物科技有限公司 一种抗人il-6单克隆抗体及应用
JP2023551542A (ja) 2020-11-30 2023-12-08 エニグマ バイオインテリジェンス，インコーポレイテッド アルツハイマー病の非侵襲的評価
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Also Published As

Publication number Publication date
CA2657763C (fr) 2016-05-31
CR10563A (es) 2009-04-14
US20080075726A1 (en) 2008-03-27
KR20090039801A (ko) 2009-04-22
MA30653B1 (fr) 2009-08-03
CA2657763A1 (fr) 2008-02-14
WO2008019061A2 (fr) 2008-02-14
MX2009001110A (es) 2009-05-11
WO2008019061A3 (fr) 2008-10-09
CO6150192A2 (es) 2010-04-20
ZA200900514B (en) 2010-04-28
IL196550A0 (en) 2011-08-01
EP2064241A2 (fr) 2009-06-03
CN101563365B (zh) 2012-10-31
BRPI0715115A2 (pt) 2013-06-04
AU2007282023A1 (en) 2008-02-14
US7919095B2 (en) 2011-04-05
KR101479537B1 (ko) 2015-01-07
EP2064241B1 (fr) 2015-10-07
EA200900037A1 (ru) 2009-10-30
AU2007282023B2 (en) 2012-09-13
JP2009545319A (ja) 2009-12-24
CN101563365A (zh) 2009-10-21

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